FURTHER PARTICULARS
Department/School:
Radiopharmacist
Wolfson Brain Imaging Centre, Department of Clinical
Neurosciences
Grade/Salary/Role Type:
Grade 7/ £27,854 - £36,298 /Academic-related role
Responsible for:
Senior Laboratory Technician
Post title:
Responsible to:
Laboratory Manager
Role Purpose
The overall duties of the role holder are the preparation, formulation and dispensing of
radiopharmaceuticals for PET imaging studies, along with ensuring good Radiopharmacy practice,
and involvement in the management of the GMP radiochemistry laboratories.
More detailed information is provided under the Role Description
[Insert Department] Organisational Chart
(See section 3 of the guidance notes)
Chairman of the Wolfson Brain Imaging Centre
Director of PET Chemistry
10-15 other researchers
Laboratory Manager
Head of Quality
Control
Cyclotron
Engineer
Research
Associate
Senior Research
Associate
X
% time
Key duties and responsibilities
1
spent/
frequency
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
Perform scheduled radiosynthesis and QC of standard
25
radiopharmaceuticals labelled either with O-15, C-11 and F-18 for PET
imaging studies at the Wolfson Brain Imaging Centre and external groups.
This will also involve radionuclide productions with the cyclotron
Assuring that the formulation and specification of the
5
radiopharmaceuticals for imaging studies meet the requirements of the
British Pharmacopeia
Deputy and supporting the Production/Laboratory Manager in scheduling
and co-coordinating the preparation of PET radiopharmaceuticals with
regard to the requirements of the PET imaging programmes, internal and
external. This will involve interacting with a wide range of staff including,
radiographers, clinical staff, administrative staff and scientists.
Deputy and supporting the Production/Laboratory Manager in the
management and maintenance of the WBIC radiochemistry laboratories.
In particular to the requirements for good manufacturing practice.
Involvement in establishing, maintaining and monitoring procedures for
good manufacturing practice (GMP) in relation to the pharmaceutical
aspects of manufacturing, dispensing, quality control and supply of
radiopharmaceuticals.
To advice WBIC staff and researchers in the establishment of
specifications and formulation for new PET radiopharmaceuticals for
human use.
Liaise closely with Addenbrooke’s pharmacy and radio pharmacy staff in
the pharmaceutical aspects of GMP for the production of
Radiopharmaceuticals
Provide support to the Production manager in internal and external audits.
10
In conjunction with relevant personnel, to develop safe procedures for the
production and manipulation of radiopharmaceuticals that comply with
Radiation Protection Requirements including acting on the results of staff
radiation doses from working in the Radiochemistry area.
Involvement in PET studies, including providing the PET imaging staff
radiochemical, scientific and technical input for the study design, results
interpretation and publications.
Assist in the maintenance and operation of documented procedures in the
QPulse document management system.
Training established and new staff and students, in particular in
pharmaceutical aspects in the preparation of radiopharmaceuticals
Radioprotection duties.
1
10
5
3
2
1
1
1
8
10
To provide appropriate service on the premises, facilities and equipment
2
used in the preparation and quality control of radiopharmaceuticals
To provide pharmaceutical advice on the storage, formulation and stability 5
of radiopharmaceuticals
To advice on aseptic techniques used in radiopharmaceutical production. 5
2
17
18
19
Responsible for Pharmaceutical advice on the procurement of starting
materials.
Advise on National European Guidelines
5
1
The Head of Section may also from time to time require the post holder to
perform other duties appropriate to the grade of the post.
Person profile
Essential knowledge, skills and experience required for role
Education &
qualifications
Specialist knowledge &
skills
Interpersonal &
communication skills
Relevant experience
BSc in Chemistry , Pharmacy or related subjects
Registration with the Royal Pharmaceutical Society of Great Britain

Ability to be able to work in a multidisciplinary team involving
clinical staff, radiographers, physicists and biologists.

Ability to assimilate a working knowledge of areas outside of
their core competency.

Ability to adhere to statutory health and safety guidelines
pertaining to a chemistry laboratory including radiation.

Good oral communication skills

Excellent writing skills, in particular the ability to write complex
scientific documents.

Flexible working to meet time lines and clinical time points.

Experience in PET radiopharmaceuticals.

Aseptic radiopharmaceutical techniques.

Good range of aseptic/manufacturing experience

Desirable would be knowledge of UK and EU GMP/GLP
regulations

A clear understanding of the unique aspects pertaining to
radiation safety and GMP for the synthesis of PET radiotracers
Summary of Terms & Conditions
Location:
Limit of Tenure:
Wolfson Brain Imaging Centre, Cambridge Biomedical Campus,
Addenbrooke’s Hospital, Cambridge CB2 0QQ
12 months.
Annual Leave:
Full time employees are entitled to annual paid leave of 6.6 weeks (or
33 days) for those working full time, plus public holidays. The leave year
runs from 1st October – 30th September.
Hours of work:
This appointment is full-time.
Pension:
The Universities Superannuation Scheme is a national scheme for
employees on academic, research and academic related scales of pay
which covers all the pre-1992 Universities and a number of other
educational and research bodies. Universities Superannuation Scheme
(USS)
3
Probation:
6 months
HOW TO APPLY
Applicants should submit a CV, a covering letter outlining suitability for the role and a
CHRIS/6 form (parts 1 and 3 only; each part in separate documents).
A CHRIS/6 form can be downloaded: http://www.admin.cam.ac.uk/offices/hr/forms/chris6/ or
requested in hard copy from the recruiting department.
Mrs Heather Carlyon is responsible for recruitment to this position and can be contacted by
email: enquiries@wbic.cam.ac.uk or by telephone: 01223 331823.
Application documents can either be emailed to enquiries@wbic.cam.ac.uk or posted to Mrs
H Carlyon, Wolfson Brain Imaging Centre, University of Cambridge, Box 65 Addenbrooke’s
Hospital, Cambridge CB2 0QQ and should be received by 5pm on the closing date.
For additional guidance and information, applicants can contact the HR Business Manager
who is responsible for the department they are applying to via
hrenquiries@admin.cam.ac.uk .
ADDITIONAL INFORMATION
Position: [insert full position title]
School: Clinical Medicine
Wolfson Brain Imaging Centre, Department of Clinical Neurosciences
The Wolfson Brain Imaging Centre (WBIC) PET Chemistry group is part of the Department of
Clinical Neuroscience and undertakes the preparation of PET radiopharmaceuticals for imaging
studies in man and preclinical. Due to the short-half lives of the radiopharmaceuticals they have to
be made locally and are produced at a state-of -the art of radiochemistry facility on the Cambridge
Biomedical Campus. The group and facility have been accredited by the Medicine and Healthcare
Regulatory Agency as a manufacturing site for medicines and investigational new products for
human use. In addition to supplying radiopharmaceuticals for studies at the WBIC the groups also
supplies the Addenbrooke’s Trust PET-CT service and other imaging groups in the south-east.
School of Clinical Medicine
The School of Clinical Medicine at the University of Cambridge (‘the Clinical School’) is one of the
UK’s leading medical schools. Its strength is built on close relationships with pre-clinical science
4
and translational partnerships with NHS organisations.
Organisation of the School
The School of Clinical Medicine comprises 12 formal Departments (Clinical Biochemistry,
Haematology, Medical Genetics, Medicine – including Anaesthesia and Clinical Pharmacology –
Obstetrics and Gynaecology, Oncology, Paediatrics, Public Health and Primary Care, Psychiatry,
Radiology, Surgery and Clinical Neurosciences) which map onto service delivery within the
University Hospital and undergraduate and postgraduate clinical teaching.
Alongside departments, the School maintains a number of cross-departmental institutes to bring
together researchers with cognate interest. At present, there are three institutes: Cambridge
Institute for Medical Research; Institute of Metabolic Science and Institute of Public Health with a
fourth planned (in Cardio-Respiratory Medical Research).
Excellence in Partnership
The Clinical School is a member of Cambridge University Health Partners, a partnership between
the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust (the main
acute trust for Cambridge), Papworth Hospital NHS Foundation Trust (a specialist Cardio-Thoracic
Trust) and the Cambridge and Peterborough NHS Foundation Trust (the regional Trust responsible
for Mental Health).
Cambridge University Health Partners is based on the Cambridge Biomedical Campus at
Addenbrooke’s Hospital. This campus hosts activities from all four of the partners and is the main
physical site for two of them. It also hosts institutes and units run by other bodies which make major
contributions to the richness of the environment. These include the Medical Research Council,
Cancer Research UK and GlaxoSmithKline. Together, the partners are intending to double the size
of the Cambridge Biomedical Campus by 2020. New developments will include additional clinical
space to accommodate expansion and improvement of healthcare; including the relocation of
Papworth Hospital, new research space associated with the clinical developments and a
commercial biomedical science park.
University of Cambridge
The University of Cambridge (http://www.cam.ac.uk/ ) is one of the world’s leading universities with
an outstanding reputation for academic achievement and research. The University comprises 31
Colleges and more than 150 departments, faculties, schools and other institutions plus a central
administration function.
Unified Administrative Service (UAS) is the university’s central administrative function. Offices of
UAS are listed here http://www.admin.cam.ac.uk/offices/ .
For maps of all university sites please follow this link: http://www.cam.ac.uk/map/ .
Benefits of working at University of Cambridge
5
There is a range of information which you may find helpful on the University’s website:
http://www.jobs.cam.ac.uk/ . This includes applying for posts, working at the University and living in
Cambridge.
To find out more about the financial, personal and recreational benefits of working at the University
of Cambridge, click on headings on final page of this document to visit current university web
pages.
Pre-employment checks required
All applicants are legally required to demonstrate the right to work/permission to work in the
UK. The requirement for any higher level pre-employment checks is dependent on the role.
Any offer of employment will be conditional upon the satisfactory outcome of these checks
and whether an outcome is satisfactory will be determined by the University.
Pre-employment checks required for this post are evidence of right to work in the UK and an
occupational health clearance.
Equal Opportunities Information
The University of Cambridge is committed to a policy and practice which require that entry
into employment with the University and progression within employment be determined only
by personal merit and by the application of criteria which are related to the duties of each
particular appointment and the relevant stipend or salary structure. No applicant for an
appointment in the University, or member of staff once appointed, will be treated less
favourably than another on the grounds of sex, (including gender reassignment), marital
status, race, ethnic or national origin, colour, or disability. If any employee considers that he
or she is suffering from unequal treatment on grounds of sex (including gender
reassignment), marital status, race, ethnic or national origin, colour, or disability, he or she
may make a complaint which will be dealt with through the agreed procedures for dealing
with grievances.
6
Information if you have a Disability
The University welcomes applications from individuals with disabilities. Our recruitment and
selection procedures follow best practice and comply with disability legislation.
The University is committed to ensuring that applicants with disabilities receive fair
treatment throughout the recruitment process. Adjustments will be made, wherever
reasonable to do so, to enable applicants to compete to the best of their ability and, if
successful, to assist them during their employment.
We encourage applicants to declare their disabilities in order that any special arrangements,
particularly for the selection process, can be accommodated. Applicants or employees can
declare a disability at any time.
Applicants wishing to discuss with or inform the University of any special arrangements
connected with their disability can contact, at any point in the recruitment process, [insert
name] who is responsible for recruitment to this position. [insert name] can be contacted by
email at [insert email] or by telephone on [insert phone number]
For additional guidance and information, applicants can contact the HR Business Manager
who is responsible for the department they are applying to via
hrenquiries@admin.cam.ac.uk .
7
CAMBRIDGE



Cambridge Festival of
Ideas
Cambridge Science
Festival
Open Cambridge
RELOCATION
ASSISTANCE
EMPLOYEE
BENEFITS



Relocation Expenses
Accommodation Service
Newcomers service
TRAVEL TO WORK
FAMILY-FRIENDLY








Childcare
Leave/Flexible working
Career breaks
Nurseries/Play schemes
HEALTH
CAMBRIDGE
BIOMEDICAL CAMPUS




CAMBens Cycle/Cars
Travel to Work Loan
Trains – season ticket
Uni4 bus discount




Frank Lee Leisure/Sports
Centre
Shops/Restaurants
On-site accommodation
Parking Facilities
Health Cash Plans
BUPA/Dental Discount
Eye Test
Occupational Health
TRAINING &
DEVELOPMENT
CAREERS



Study/Sabbatical Leave
Unpaid Leave
Careers Service

Institute for Continuing
Education
Personal Development
Language Centre


RECREATION




WELLBEING




Mentoring
Counselling Service
Chaplaincy
Disability Resources
FINANCIAL




CAMBens discounts
Payroll giving
Shared Equity Scheme
Contribution Rewards
University Sports
University Social Club
College Entry
Local Attractions