Membrane Transport Membrane Transport What are some substances commonly transported across membranes? Membrane Transport What are the three mechanisms used to move solute molecules across the membrane? Simple Diffusion What is involved in this transport process? What can cross the plasma membrane via simple diffusion? Simple Diffusion How does osmosis differ from simple diffusion? Simple Diffusion What are the major factors that influence diffusion across a membrane? Simple Diffusion What specifically determines the rate of simple diffusion? vinward = PΔS P = permeability coefficient ΔS = concentration gradient Simple Diffusion What is the partition coefficient and how does it affect diffusion? Facilitated Diffusion How is facilitated diffusion different from simple diffusion? Facilitated Diffusion What do we know about transporters? What is the difference between a transporter or carrier protein and a channel protein? Facilitated Diffusion Facilitated Diffusion In what ways do transporters resemble enzymes? What kinds of molecules are transported via facilitated diffusion? Facilitated Diffusion What do we specifically know about the transport of glucose in red blood cells? Facilitated Diffusion What is the difference between ion channels, porins and aquaporins? Active Transport How is active transport similar to and different from facilitated diffusion? Active Transport What is the difference between direct and indirect active transport? Active Transport How can we calculate the energy needed to transport uncharged molecules across a membrane? ΔG = RT ln [S]inside/[S]outside free energy need to transport molecules from outside to inside of membrane Active Transport If the solute being transported has a charge how does that affect the energy requirement? ΔG = RT ln [S]inside/[S]outside + zFVm z = charge on ion F = 23,062 cal/mol-V (Faraday constant) Vm = membrane potential – in volts Sum of concentration & charge gradients = electrochemical gradient Active Transport What are the four types of transport ATPases? Active Transport What do we currently know about the sodium-potassium pump? Active Transport Active Transport Why is this sodium-potassium pump so important for animal cells? Active Transport Why is the Na+/glucose symporter an example of indirect active transport? Active Transport Active Transport What does the bacteriodopsin pump do and where is it found? Active Transport