BENIGN PAROXYSMAL POSITIONAL VERTIGO WASEEM WATAD Basic Anatomy BPPV Barany 1921 Dix-Hallpike 1952 – important features of nystagmus Abnormal sensation of motion elicited by certain critical positions Provocative position nystagmus At least 20% of vertigo Underestimated BPPV … Subclassification : scc post/lat/ant/bilat Pathophysiology : – Canalithiasis – cupulolithiasis Pathophysiology Pathophysiology (cont.) Cupulolithiasis : – Harold Schuknecht 1962 – Densities (otocania) adherent to cupula of crista ampullaris – Basophilic particles -1969 Canalithiasis : – John Epley – 1980 – Densities free floating in canal portion – Parnes , McClure – 1991 found particles in post SCC BPPV ... Frequency : 10-64/100000 Sex : 64% women Age : older population ( 51-57) younger than 35 – head trauma. History : – – – – sudden days-weeks occassionally months -years episodes. Physical : – neurological examination – normal – except – Dix-Hallpike pathognomonic BPPV … Nystagmus : characterization and types – RT / LT , vertical / horizontal , changing – Tortional = Rotational – clockwise / counterclockwise – Geotropic- toward the earth – Ageotropic – opposite BPPV … Classic post SCC – geotropic rotatory nystagmus Horizontal SCC – purely horizontal nystagmus Non-fatiguing nystagmus – cupulolithiasis > canalithiasis Classic BPPV Involved the POST SCC – Geotropic NG with affected ear down – Rotatory , fast phase toward the undermost ear – Latency – few seconds – Duration – limited < 20 seconds – Reversal upon return upright position – Response decline upon repetitive provocation Lat. SCC PPV Most common atypical BPPV 3-9% of cases Consequence of Epley maneuver Horizontal purely nystagmus Cupulolithiasis rather than canalithiasis Modified Epley / lampert maneuver … Lat. SCC PPV Ant. SCC PPV Rare – 2% Down-beating /torsional NG for the opposite ear on Dix-Hallpike maneuver BPPV - Causes Predisposing factors : – Inactivity – Acute alcoholism – Major surgery – CNS disease Causes ( cont. ) Idiopathic – 39% Ear disease – 29% – OM – 9% – Vestibular neuritis – 7% – Menier’s dis – 7% – Otosclerosis – 4% – Sudden SNHL – 2% Trauma – 21% Causes ( cont. ) Trauma – 21% CNS diseases – 11% Acustic neuroma – 2% Cervical vertigo – 2% BPPV - D.D Menier’s disease Inner ear concussion Alcohol intoxication Labyrinthitis Vascular loop syndrome Post. Fossa lesions : acustic neuroma , meningioma Central origion : stroke , MS , cerebellar degeneration Vertibral artery insuffeciency Cervical vertigo BPPV - Treatment Watchful waiting Vestibular suppressant medications Vestibular rehabilitation Canalith repositioning Surgery care – – – – Labyrinthectomy Post. Canal occlusion Singula neurectomy Transtympanic aminpglycoside application Trials about BPPV General Labeled benign paroxysmal positional vertigo is not always benign Evaluation of the effectiveness of canalith reepositioning procedurs – CRP Several studies … Trials … Blakely – 1994 : – 50% improvement in the control and CRP group !! ( 2-3 months) Lynn – 1995 : – Randomized-controlled : 89% negative DH in CRP group , 27% in the control group John Li (1995) : Trials… John Li (1995) : – Comparison CRP / CRP + mastoid oscillation and control – Modified Epley maneuver – Use of colar and head elevation after CRP – No spontaneous resolution within aweek – 60% symptoms improvement in CRP group – 92% symptoms improvement in CRP +mastoid oscilation and 70% negative DH Trials… R. steenerson –1996 : – Comparison of CRP and vestibular habituation training – Tow approaches are effective in symptomatic relief ( 3 months) – CRP faster relief and fewer treatments Trials … K. Yimatae (2003) – Randomized-controoled – Modified Epley maneuver, no mastoid oscillator and no instructions after the maneuver – Subjective and objective weekly follow-up – CRP group – 76% negative DH, 48% control group – CRP group – 96% symptoms improvement , 90% control group – Non-cured patients need > 6 procedures in 2 weeks , should considering liberatory maneuver Elderly population and BPPV S. Angeli – 2003 : – Effectiveness of CRP and VR – Modified Epley : Elderly comorbidities : degenerative osteoarthritis disease , CVA , peripheral neuropathy, cognitive and autonomic dysfunctions S/E of CRP – neck torsion and extension result in vertibrobasilar artery insufficiency, strain on the spine column, dislodged carotid a. emboli Avoid liberatory maneuver – 64% CRP group – negative DH after a month – Overall 77% with CRP and VR CRP Meta-Analysis B. Woodworth - 2004 CRP - First line of treatment – Non-invasive – Easy to perform in the office – No need to expensive instrumentations – Repeat maneuver if needed – Potential to provide rapid relief of vertigo Meta - Analysis 9 randomized-controlled trials Symptoms resolution and elimination of positive Dix-Hallpike test CRP more effective than control ( x5 ) Untreated patients - symptoms improvements with time but positive DH So Resolution of vertigo – avoidance of provocative positions CRP – Epley maneuver CRP – Semont maneuver Mastoid oscillator Brandt-Daroff Exsercise Lampert maneuver- Lat. SCC BPPV Vestibular rehabilitaions Complications of CRP Failure – 25% (12%-56) Recurrence – 13% in 6 months Side effects – Nausea – Vomiting – Fainting – Sweating Worse vertigo – LAT SCC PPV THANK YOU …