• Types of hairs Hair – Lanugo – fine, nonpigmented, downy hairs that cover the body of the fetus – Vellus hairs – short, fine, pale hairs barely visible to the naked eye – Terminal hairs – long, coarse, heavily pigmented hairs • Hair color is determined by the amount and type of melanin. Skin Glands • Recall from Chapter 4 that glands are epithelial cells that secrete a substance. • Sebaceous (oil) glands are connected to hair follicles. – They secrete an oily substance called sebum which does 2 important things: • Prevents dehydration of hair and skin • Inhibits growth of certain bacteria Skin Glands • In addition to oil glands, there are 2 types of skin sweat glands (also called sudoriferous glands). Both are simple, coiled tubular glands. – Eccrine sweat glands are the most numerous. They secrete a watery solution (600 ml per day) that helps to cool the body and eliminates small amounts of waste. – Apocrine sweat glands are located mainly in the skin of the axilla, groin, areolae, and bearded facial regions of adult males. They secrete a slightly viscous sweat. Skin Glands • Eccrine sweat glands release sweat in response to an emotional stress such as fear or embarrassment. This type of sweating is referred to as emotional sweating or a “cold sweat”. • The secretory portion of apocrine sweat glands is located mostly in the subcutaneous layer, and the excretory duct opens into hair follicles, with sweat secreted during emotional stress and sexual excitement. – Much of body odor is due to apocrine sweat. Skin Glands • Ceruminous glands are modified sweat glands located in the ear canal. – Along with nearby sebaceous glands, they are involved in producing a waxy secretion called cerumen (earwax) which provides a sticky barrier that prevents entry of foreign bodies into the ear canal. Nails • Nails are composed of hard, keratinized epidermal cells located over the dorsal surfaces of the ends of fingers and toes. • Nail structures include: – Free edge – Transparent nail body (plate) with a whitish lunula at its base – Nail root embedded in a fold of skin Nails Anatomy Overview: Interactive Animation • The Integument and Disease Resistance You must be connected to the internet to run this animation Maintaining Homeostasis Skin damage sets in motion a sequence of events that repairs the skin to its normal (or near-normal) structure and function. Wound Healing • Two kinds of wound-healing processes can occur, depending on the depth of the injury. – Epidermal wound healing occurs following superficial wounds that affect only the epidermis. • Return to normal function is the rule. – Deep wound healing occurs when an injury extends to the dermis and subcutaneous layer. • Loss of some function and development of scar tissue is the rule. Wound Healing We will observe similar attempts at homeostasis in all the organ systems we study for the remainder of the year. Wound Healing We will observe similar attempts at homeostasis in all the organ systems we study for the remainder of the year. Burns • A burn is tissue damage caused by excessive heat, electricity, radioactivity, or corrosive chemicals that denature (break down) the proteins in the skin cells. – Burns destroy some of the skin's important contributions to homeostasis—protection against microbial invasion and desiccation, and thermoregulation. • Burns are graded according to their severity. Burns • A first-degree burn involves only the epidermis – It is characterized by mild pain and erythema (redness) but no blisters and skin functions remain intact. Burns • A second-degree burn destroys the epidermis and part of the dermis - some skin functions are lost. – Redness, blister formation, edema, and pain result. Burns • A third-degree burn is a full-thickness burn (destroys the epidermis, dermis, and subcutaneous layer). – Most skin functions are lost, and the region is numb because sensory nerve endings have been destroyed. Burns • According to the American Burn Association's classification of burn injury, a major burn includes: o – 3 burns over 10% of body surface area; or o – 2 burns over 25% of body surface area; or o – Any 3 burns on the face, hands, feet, or perineum (which includes the anal and urogenital regions) • When the burn area exceeds 70%, more than half the victims die. Burns • A quick means for estimating the surface area affected by a burn in an adult is the rule of nines: – Count 9% if both the anterior and posterior surfaces of the head and neck are affected. – Count 9% for both the anterior and posterior surfaces of each upper limb (total of 18% for both upper limbs). – Count four times nine or 36% for both the anterior and posterior surfaces of the trunk, including the buttocks. – Count 9% for the anterior and 9% for the posterior surfaces of each lower limb as far up as the buttocks (total of 36% for both lower limbs). Burns Development of the Integumentary System • The epidermis develops from the ectoderm. – Nails, hair, and skin glands are epidermal derivatives. • The dermis develops from the mesoderm. Aging • The integumentary system changes with age: – Wrinkles develop. – Dehydration and cracking occurs. – Sweat production increases. – An increase in the numbers of functional melanocytes results in gray hair and atypical skin pigmentation. – Subcutaneous fat is lost, and there is a general decrease in skin thickness. – Nails may also become more brittle. Aging • With age, there is also an increased susceptibility to pathological conditions (as demonstrated by this decubitus ulcer). – These type of pressure ulcers (“bed sores”) are an all-to-common occurrence in nursing homes. End of Chapter 5 Copyright 2012 John Wiley & Sons, Inc. All rights reserved. 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