Biochemistry of Cells Chapter 2.3 1 Nucleic Acids 2 We will discuss Nucleic Acids more next semester when we study Genetics! Nucleic Acids DNA 3 Nucleic Acids Contains Hydrogen, Oxygen, Nitrogen, Carbon, and Phosphorus Are Polymers assembled from individual monomers known as nucleotides Nucleotides consist of 3 parts 5-carbon sugar phosphate group nitrogenous base Copyright Cmassengale 4 Nucleotide – Nucleic acid monomer 5 Nucleic Acids Store hereditary information Contain information for making all the body’s proteins Two types exist DNA RNA 6 Nucleic Acids DNA contains deoxyribose sugar RNA contains ribose sugar 7 Bases Each DNA nucleotide has one of the following bases: –Adenine (A) Thymine (T) Cytosine (C) –Guanine (G) –Thymine (T) –Cytosine (C) Adenine (A) Guanine (G) 8 Nucleic Acids - DNA 9 Nucleotide Monomers Form long chains called DNA Backbone Nucleotide Nucleotides are joined by sugars & phosphates on the side Bases DNA strand 10 DNA Two strands of DNA join together to form a double helix Double helix 11 12 RNA – Ribonucleic Acid Nitrogenous base (A,G,C, or U) Ribose sugar has an extra –OH or hydroxyl group It has the base uracil (U) instead of thymine (T) Uracil Phosphate group Sugar (ribose) Copyright Cmassengale 13 ATP – Cellular Energy •ATP is used by cells for energy •Adenosine triphosphate •Made of a nucleotide with 3 phosphate groups Copyright Cmassengale 14 ATP – Cellular Energy • Energy is stored in the chemical bonds of ATP • The last 2 phosphate bonds are HIGH ENERGY • Breaking the last phosphate bond • releases energy for cellular work and produces ADP and a free phosphate ADP (adenosine Diphosphate) can be rejoined to the free phosphate to make more ATP 15 Summary of Key Concepts 16 Macromolecules 17 Macromolecules 18 End Summarize your notes 19