The ACUTE ABDOMEN Simon Lau Mike Bozin The Acute Abdomen: an acute change in the condition of the intra abdominal organs Usually related to inflammation or infection Demands IMMEDIATE and accurate diagnosis (but this does not always correlate with the need for an operation) Abdominal Pain One of the most frequent presentations to EDs Most are self limiting Some are not! Case 1 27yo female presents with 1d of abdominal pain Associated with: Anorexia Nausea, no vomiting Some diarrhoea Visceral vs Parietal Visceral Pain: Related to stretching of the walls of hollow viscera, or the capsules of solid ones Dull Poorly localised but usually central Visceral vs Parietal Pain Parietal Pain Origin anywhere in the abdominal wall from the skin to the parietal peritoneum Intense Well localised Transition from Visceral to Parietal Initial visceral pain irritates parietal peritoneum, causing parietal pain wherever they are in contact Cont Case 1 Abdominal Pain: Initially midline/umbilical Over 24/24 transitioned to the RIF Severe, constant Applied Anatomy What anatomical structures reside in the Right Iliac Fossa? (in a girl) The Right Iliac Fossa Caecum Appendix Ileocaecal junction/valve Right Ovary/Fallopian tube Right Ureter Examination HR110 BP95/70 O2: 98% 4LNP RR20 T37.8⁰C Abdo Ex: RIF tenderness Percussion tenderness Rovsing Sign PR: nil blood, nil melena Investigations FBE: 120/15.2/214 neut 11.2 UEC: 140/4.3 Cr 64 eGFR >90 INR: 1.0 β-HCG: neg Urinalysis: NAD Imaging??? DDx? Acute Appendicitis Inflammation of the appendix, usually secondary to obstruction of the appendiceal lumen Alvarado Score Complications of untreated appendicitis? Perforation and peritonitis Appendiceal abscess Other DDx’s GIT: Diverticulitis Bowel obstruction Volvulus/strangulation Cx of hernias Gynaecological: Ectopic pregnancy Adnexal torsion Urological: Pyelonephritis Renal stones Testicular torsion Vascular: Ischaemic colitis Case 2 46yo male presents with 12hrs of worsening abdominal pain Moderate in severity Initially colicky but now constant Located in the RUQ with radiation to the tip of the right shoulder Associated with nausea and vomiting and fevers Applied Anatomy What structures are found in the RUQ? The Right Upper Quadrant Liver Gall Bladder Biliary Tree Pancreas Stomach Duodenum Right kidney Examination HR: 115 BP: 120/70 RR: 19 O2: 99% 2L NP T: 38.1⁰C Abdo Ex: Tender RUQ with some (voluntary) guarding Murphy’s sign positive Investigations FBE: 123/13.9/285 neut 10.2 UEC: normal LFTs: bilirubin, GGT and ALP elevated Imaging?? DDx? Cholecystitis Inflammation of the gallbladder, most commonly from obstruction of the cystic duct Cf with choleduocholithiasis and cholangitis and biliary colic Cont Cholecystitis Imaging: US Abdo or CT A/P Treatment IV resus Analgesia Abx Laproscopic cholecystectomy Other DDx’s? Hepatobiliary: Choleduocholithiasis Cholangitis Pancreatitis GIT: Perforated peptic/duodenal ulcer Gastritis/GORD Urological: Pyelonephritis Renal stones Case 3 87yo male presents to the ED with sudden onset abdominal pain Severe and constant Initially developed in the LIF but quickly became widespread Associated with one large passage of bloody diarrhoea Cont Case 3 PMHx: IHD – AMI 2yrs ago with PCI T2DM – OHG only AF – warfarinised recently PVD – Fem-Pop Bypass Graft 4yrs ago Nil history of abdominal surgery Meds: Warfarin, β-blocker, ACE-I, metformin, aspirin, statin Active smoker 4-5 cigarettes per day, 40+ PYH Examination HR: 130, BP: 90/60, O2: 99% 2LNP, RR: 17, T: 37.9⁰C Looks flat/sick. Unwilling to move much. Drowsy Abdo Ex: Abdominal guarding and rigidity Investigations FBE: 75/15.2/246 neut 11.2 UEC: 150/3.2 Cr 265 eGFR 30 (baseline Cr 125) LFTs: normal Coags: INR 1.6 ABG: pH 7.29 pCO2 29 HCO3 19 lactate 5.2 AXR: dilated oedematous bowel loops DDx? Use Applied Anatomy! Descending and Sigmoid Colon Ureter Left Ovary/Fallopian Tube Treatment: IV resuscitation Blood Cultures and Abx NGT, IDC Vit K (IV) to reverse INR Consent for urgent laparotomy + washout +/- proceed (eg Hartman’s). Consider need for intraoperative Angiogram Hartman’s Procedure Lets go back to Case 1 27yo female presents with 1d of abdominal pain Abdominal Pain: Initially midline/umbilical Over 24/24 transitioned to the RIF Severe, constant Further Hx: LMP 8 weeks ago No PV bleding Smoker Hx of chlamydia Previous laparoscopic surgery for endometriosis O/E Pain 2/10 after 10mg morphine IV Obs: HR110 BP95/70 O2: 98% 4LNP RR20 T37.8⁰C Abdominal examination as above What else do you need to do? ALL FEMALE PATIENTS OF REPRODUCTIVE AGE ARE PREGNANT UNTIL PROVEN OTHERWISE - b-HCG! Speculum examination and bimanual examination O&G Differentials Obstetric Non-Obstetric Gynaecological Early Pregnancy - Ectopic pregnancy - Miscarriage Late Pregnancy - Placental abruption - Uterine rupture - Labour / PPROM - Braxton-Hicks - HELLP - Acute fatty liver - Choramnionitis - Symphysis pubis dysfunction - Round ligament pain - Fibroid degeneration - - Ovarian torsion - PID - Ruptured ovarian cyst - Endometriosis - Adenomyosis - Mittelschmertz Appendicitis Pyelonephritis UTI GORD Constipation Pancreatitis Renal colic Cholecystitis Bowel obstruction Diverticulitis IBD Trauma / Assault Medical causes (pneumonia, DKA) ACUTE ABDOMEN + POSITIVE PREGNANCY = ECTOPIC until proven otherwise.. Risk factors for Ectopic pregnancy Smoking Clomiphene IUD PID Previous ectopic pregnancy Adhesions Pelvic and tubal surgery Endometriosis Pelvic masses Chromosomal abnormalities Investigation Cultures: urine B-HCG Bloods: FBE, UEC, LFT, G+H, COAG, Serum B-HCG, Serum progesterone Serum B-HCG >1500 I/U should see gestational sac Serum B-HCG > 10,000 should see heart beat Serum B-HCG should double every 48 hours Imaging: Transvaginal ultrasound Scopic: Diagnostic laparoscopy FIRST RESUSCITATITE, then.. IF PATIENT IS UNSTABLE DESPITE RESUSITATION URGENT LAPAROTOMY IS INDICATED Management Medical: ONLY if fulfill criteria Methotrexate Anti-D if mum Rh-ve Follow up Contraception for 3 months as methotrexate teratogenic! Surgical: Anti-D if mum Rh-ve Diagnostic Laparoscopy if patient is haemodynamically stable Laparotomy if patient unstable Salpingectomy or Salpingotomy Management Ovarian Torsion Torsion of ovary on its vascular, tubal and ligamentous pedicle (adnexal torsion) Results in ischaemia and eventual infarction if not relieved GYNAECOLOGICAL EMERGENCY Risk factors: Ovarian mass Cyst More common in reproductive age Sudden onset lower quadrant visceral pain Radiate to flank or inner thigh N+V Can sometimes develop slowly Tender lower quadrant Adnexal tenderness on bimanual examination +/- palpable mass Investigation and Management B-HCG to rule out ectopic pregnancy! WCC – tubo-ovarian abscess Urinalysis Doppler Ultrasound >50% sensitivity for torsion, but arterial flow does not rule out Absence of arterial flow high predictive value Laparoscopy / laparotomy +/- salpingo-oophorectomy Ovarian Torsion Other Differentials NOT TO MISS ΑAA Testicular torsion AMI Lower lobe pneumonia Questions???