Spring, 2013
CHEM 109. General, Organic, and Biological Chemistry for Nursing, 4T, 3 credits
Instructor: Dr. Mallory Cortez
Office: 133 Beauregard
Phone: 985-448-4167
Email: mallory.cortez@nicholls.edu
Course Meeting: 4MW: Mon/Wed 10:45 pm-12:05 pm
Room: 165 Beauregard
Office Hours: Mon/Wed 12:05 pm – 1:05 pm
Tues/Thurs 9:00 am-11:00 am; 2:30 pm-3:30 pm
Friday
10:00am-12:00 pm
Whenever I am in the office you are welcome to come in and ask questions.
Course Description: Chem 109. General, Organic, and Biological Chemistry for Nursing . 3-3-0. Nondevelopmental Mathematics placement. General, Organic, and Biological Chemistry for Nursing will
place an emphasis is on broad aspects of general, organic, and biochemistry necessary for the
comprehension of biological processes occurring within the human body. A one-semester course
designed for students in various health related programs – nursing, dietetics, etc. Degree credit will not
be given for both CHEM 109 and 208, or 435. Basic computer knowledge is required for students
enrolled in this course. (40.0599)
PREREQUISITES: Non-developmental mathematics placement
REQUIRED TEXTS AND OTHER MATERIALS:
1) General, Organic, and Biochemistry , 2nd edition by Frost, Deal, & Timberlake (ISBN 978-0-3219-
4506-8) or (ISBN 978-0-3218-0263-7) plus Mastering Chemistry
2) IClicker2
GENERAL EDUCATION STUDENT LEARNING OUTCOMES:
CHEM 109, as a course specially designed for nursing students, fulfills three hours of general education
requirements in the area of the natural sciences and is this designed to enable students to meet the
following broad outcome for all natural sciences:
Goal: Upon completion of the undergraduate curriculum, students will be able to comprehend and to
apply the basic principles of science and methods of scientific inquiry.
Students will be able to
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4.
Differentiate among facts, laws, theories, and hypotheses
Define major concepts, principles, and fundamental theories in at least one area of science
Demonstrate an understanding of the basic terminology in at least one area of science
Formulate a hypothesis, given a simple problem or questions, and design a valid experiment to
test it
5. Make informed decisions on contemporary consumer or social issues demanding scientific
literacy
For further explanation of the learning objectives associated with this goal, go to
http://www.nicholls.edu/gened/goals_objectives.html.
STUDENT OUTCOME OBJECTIVES: This one semester course is designed to introduce students to the general
principles of chemistry geared to the allied health major including organic chemistry and biochemistry.
The principles fall into the four main areas of:
1. Measurement and Mathematical Concepts (MMC)
2. Molecular Structures (MS)
3. Solution and Acid/Base Chemistry (ABC)
4. Biochemistry (BC)
Upon successful completion of this course, the student should be able to:
 Classify different forms of matter. Distinguish physical and chemical properties. Identify and
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describe the properties of metals and nonmetals (MS).
Measuring items and applying rules for significant figures correctly (MMC).
Convert English to metric units of measurement, and vice-versa. Perform simple dosage
calculations through unit conversions (MMC).
Explain the basic relationships of gas pressure, temperature, volume, and amount. Apply
Boyle’s Law and Charles’ Law (MMC).
Identify the number of subatomic particles present in atoms and ions. Distinguish between
isotopes and ions by the number of subatomic particles present. Distinguish Mass Number
from Atomic Mass (MS).
Identify specific charges on ions. Distinguish and name ionic and binary covalent
compounds. Identify the number of valence electrons in the main group elements (MS).
Determine the molecular shapes of carbon, nitrogen, and oxygen in a covalent compound.
Determine the polarity of the covalent bond and a covalent compound (MS).
Distinguish representatives of organic compounds (including Lewis, condensed, skeletal, 3-D
ball, and stick structures). Define structural isomer (MS).
Recognize organic families and hydrocarbon functional groups (MS).
Distinguish isomers of organic compounds as structural, cis/trans, enatiomers, and
diastereomers. Identify chiral centers in organic molecules (MS).
Identify a carbohydrate by its molecular formula and functional groups. Distinguish the
simple sugars by structure and function (BC).
Determine the ring structure of a linear monosaccharide. Recognize and name a glycosidic
linkage. Identify the products of the following reactions for carbohydrates: condensation,
hydrolysis, oxidation and reduction. Describe what is a reducing sugar (BC).
Describe the structure and function of complex carbohydrates, and identify the
corresponding glycosidic linkages (BC).
 Draw fatty acid salts in water, a “micelle”. Describe the difference between a saturated
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versus an unsaturated fatty acid. Draw a triglyceride, and identify its functional groups.
Distinguish between a fat and an oil.
Distinguish the structural differences between a triglyceride and a phospholipid. Identify the
function of phospholipids. Draw a phospholipid bilayer (BC).
Determine the direction of the flow of water across a membrane in osmosis and diffusion
(ABC). Distinguish the three main mechanisms of transport across a biological membrane
(BC).
Distinguish between a solution and a suspension. Distinguish solutions as electrolyte, nonelectrolyte, or weak electrolyte (ABC).
Calculate the concentration of a solution. Describe how you would make an aqueous
solution of a known concentration using a solid solute or concentrated stock solution (ABC).
Identify and learn how to name the strong acids and bases. Identify an acid, base, conjugate
acid and conjugate base. Write conjugate acid-base reactions. Write a balanced
neutralization reaction (ABC).
Predict the strength of a weak acid from its Ka, or the pKa. Determine the acidity of a
solution from the pH scale. Calculate the pH of a solution from its hydronium ion
concentration and vice-versa (ABC).
Explain how buffering works, and the components that make up a buffer. Apply
LeChatelier’s principle to the bicarbonate buffer system (ABC).
Determine the predominant species present in aqueous solution for the functional groups
amine and carboxylic acid, found in amino acids, at a given pH (BC).
Draw the general structure of an amino acid in zwitterion form. Identify the functional
groups: amide, thiol, aromatic, and disulfide. Classify the amino acids by R- group polarity
and charge (BC).
Describe the levels of structure and various functions of proteins (BC).
Establish whether a chemical reaction is exothermic or endothermic, by using a reaction free
energy diagram. Apply the factors that affect enzyme activity to a given situation.
Distinguish between competitive and noncompetitive types of inhibition (BC).
Identify parts of a nucleotide and a nucleic acid. Distinguish purines and pyrimidines.
Identify the structure and function of the nucleic acids DNA and RNA. Provide the
complementary strand for a given strand of DNA showing the 5’ and 3’ ends (BC).
COURSE CONTENT:
Chapter 1: Chemistry Basics-Matter and Measurement
Chapter 2: Atoms and Radioactivity
Chapter 3: Compounds-Putting Particles Together
Chapter 4: Introduction to Organic Compounds
Chapter 5: Chemical Reactions
Chapter 6: Carbohydrates-Life’s Sweet Molecules
Chapter 7: What’s the Attraction? State Changes, Solubility, and Lipids
Chapter 8: Solution Chemistry-How Sweet Is Your Tea?
Chapter 9: Acids, Bases, and Buffers in the Body
Chapter 10: Proteins-Workers of the Cell
Chapter 11: Nucleic Acids-Big Molecules with a Big Role
Chapter 12: Food as Fuel-A Metabolic Overview
Homework: Homework will be given for each chapter in Mastering Chemistry and will be available at
the beginning of each chapter. The due date will be two days after finishing the chapter. Homework will
not be graded, but points will be given for completion. It is your responsibility to make sure that you
understand the homework. If you have problem doing the homework, please see me so that I can help
you. No late homework will be accepted after the due date. The purpose of homework is to help you
practice and prepare for the exam. The total points for each homework assignment will be 5 points.
Quizzes: Quizzes will be given on Mastering Chemistry for each chapter or with the iclicker2 in class.
Due dates for quizzes will be announced in class. Quizzes will be 10 pts each. The lowest three quiz
grades will be dropped. The purpose of these quizzes is to keep students up to date on the materials as
well as prepare students for the tests. No make-ups given for quizzes.
Bonus Points:
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30 points will be given for attendance and participation. See details below under
attendance. Iclickers will also be used in throughout the power points for extra points.
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Points will also be given with iclicker2 questions during the lecture
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Tutorials on Mastering Chemistry will also be worth bonus points
Exams: 4 exams and 1 comprehensive Final exam will be given. One exam, with the exception of the
finale exam, may be dropped. Each exam will be given after finishing 3 chapters.
Review Sessions: Review sessions will be given before every test to discuss problems and assignments.
The time for these sessions will be announced.
Grading: The grading will be as follows
Item
Total Points
Homework
60
Quizzes
90
Exams
400
Final Exam
200
METHOD OF EVALUATION: The grades earned will be as follows
90%-100% A
80%-89% B
65%-79% C
55%-64% D
MAKE-UP POLICY: Make-up exams for excused absences will be given on the last day of class only. This is
the only opportunity to take a make-up exam. Other assignments will not be accepted late.
ATTENDANCE POLICY: It is highly recommended that you attend class every day. Promptness is expected. I
will give 30 points extra credit for attendance and participation. A student who misses 1 to 2 classes will
earn 20 points, 3 to 4 classes will earn 10 points, 5 to 6 classes will earn 5 points, and missing 7 or more
classes will result in no extra points. A sign in sheet will be available at the beginning of the class. It is
the student’s responsibility to sign that they attended the class.
ACADEMIC HONESTY POLICY: Any student found cheating will be subject to the penalties as stated in the
Student Code of Conduct handbook; including but not limited to a score of zero on exam, expulsion from
the class or expulsion from the University.
SEMESTER WITHDRAWALS: The last day to withdraw from the class with a “W” is November 5th 2013.
ACADEMIC DISABILITIES POLICY: If you have a documented disability that requires assistance, you will need
to register with the Office of Disability Services for coordination of your academic accommodations. The
Office of Disability Services is located in Peltier Hall, Room 100-A. The phone number is (985) 448-4430
(TDD 449-7002).
CLASS DISRUPTIONS: Are not tolerated. The use of cell phones, pager and/or any other electronic personal
devise in class is prohibited. Any infractions will result in the dismissal from class.
ACADEMIC GRIEVANCES: The proper procedure for filing grade appeals or grievances related to academic
matters is listed in Section 5 of the Code of Student Conduct and at the following link:
http://www.nicholls.edu/documents/student_life/code_of_conduct.pdf.
ASSISTANCE WITH STUDYING AND ASSIGMENTS
The Tutoring Center at 143 Peltier Hall. Call 985-448-4100, email: tutoring@nicholls.edu, or
visit http://www.nicholls.edu/academic-enhancement/
The Writing Center at 144 Peltier Hall. Call 985-448-4100, email: tutoring@nicholls.edu, or
visit http://www.nicholls.edu/academic-enhancement/
Online Tutoring through Moodle. Look for the Brainfuse log-in link on the home
page,http://moodle2.nicholls.edu/moodle/
CONTINUED LEARNING FOLLOWING AN EXTREME EMERGENCY:
In order to make continued learning possible following an extreme emergency, students are responsible
for:
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Reading regular emergency notifications on the NSU website;
Knowing how to use and access Blackboard/moodle;
Being familiar with emergency guidelines;
Evacuating textbooks and other course materials;
Knowing their moodle student login and password;
Contacting faculty regarding their intentions for completing the course.
Faculty are responsible for:
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The development in the use of the moodle software;
Having a plan for continuing their courses using only Blackboard and email;
Continuing their course in whatever way suits the completion of the course best, and being
creative in the continuation of these courses;
Making adjustments or compensations to a student’s progress in special programs with labs,
clinical sequences or the like only in the immediate semester following the emergency.
Note: This is not a binding contract. This syllabus is subject to change throughout the course.
Tentative Schedule:
Date
Aug. 19
Topic
University Closed
Date
Aug. 21
Topic
Introduction
The Scientific Approach
Ch. 1.1 Classifying Matter
Ch. 1.2 Elements, Compounds,
and the Periodic table
Ch. 1.3 Math Counts
Ch. 1.4 Matter: “Stuff”
Aug. 26
Ch. 1.5 Measuring Matter
Ch. 1.6 How Matter Changes
Ch. 2.1 Atoms and their
Components
Chapter 2.2. Atomic Number
and Mass Number
Ch. 2.3 Isotopes and Atomic
Mass
Ch. 2.4 Radioactivity and
Radioisotopes
Aug. 28
Sept. 2
Labor Day, No Class
Sept. 4
Sept. 9
Homework Ch. 2 Due
Quiz 3
Review For Exam 1
Ch. 4.1 Alkanes
Ch. 4.2 Structure of Organic
Compounds
Ch. 4.3 Families of Organic
Compounds
Ch. 4.4 Nomenclature
Sept. 11
Exam 1 Chapters 1, 2, and 3
Homework Ch. 3 Due
Sept. 17
Ch. 4.4 Nomenclature
Ch. 4.5 Isomerism in Organic
Compounds
Ch. 5.1 Thermodynamics
Ch.5.2 Chem. Reactions:
Kinetics
Sept. 23
Quiz 4
Ch. 5.3 Overview of Chem.
Reactions
Ch. 5.4 Oxidation and
Reduction
Ch. 5.5 Organic Reactions:
Condensation and Hydrolysis
Ch. 5.6 Organic Addition
Reactions to Alkenes
Sept. 25
Homework Ch. 4 Due
Ch. 6.1 Classes of
Carbohydrates
Ch. 6.2 Functional Groups in
Monosaccharides
Ch. 6.3 Stereochemistry in
Monosaccharides
Sept. 30
Quiz 5
Ch. 6.4 Reactions of
Monosaccharides
6.5 Disaccharides
6.6 Polysaccharides
6.7 Carbohydrates and Blood
Oct. 3
Homework Ch. 5 Due
Quiz 6
Review for Exam 2
Sept. 16
Quiz 1
Ch. 2.5 Nuclear Equations and
Radioactive Decay
Ch. 2.6 Radiation Units and
Half-Lives
Ch. 2.7 Medical Applications
for Radioisotopes
Ch. 3.1 Electron
Arrangements and the Octete
Rule
Ch. 3.2 In search of an Octet,
Part 1: Ion Formation
Homework Ch. 1 Due
Quiz 2
Ch. 3.3 Ionic CompoundsElectron Give and Take
Ch. 3.4 In Search of an Octet,
Part 2: Covalent Bonding
Ch. 3.5 TheMole
Ch. 3.6 Getting Covalent
Compounds into Shape
Ch. 3.7 Electronegativity and
Molecular Polarity
Oct. 7
EXAM 2
Chapters 4,5, and 6
Homework Ch. 6 Due
Oct. 9
Oct. 14
Ch.7.5 Dietary Lipids and
Trans Fats
Ch. 7.6 Attractive Forces and
the Cell Membrane
Ch. 8.1 Solutions are Mixes
Ch. 8.2 Formation of
Solutions
Ch. 8.3 Chem. Equations for
Solution Formation
Quiz 8
Homework Ch. 7 Due
Ch. 9.1 Acids and BasesDefinitions
Ch. 9.2 Strong Acids and
Bases
Ch. 9.3 Chem Equilibrium
Ch. 9.4 Weak Acids and Bases
Ch. 9.5 pH and the pH Scale
Quiz 9
Review Exam 3
Oct. 16
Nov. 4
Oct. 21
Ch. 7.1 Types of Attractive
Forces
Ch. 7.2 Liquids and Solids
Ch. 7.3 Attractive Forces and
Solubility
Ch. 7.4 Gases
Quiz 7
Ch. 8.4 Concentrations
Ch. 8.5 Dilution
Ch. 8.6 Osmosis and Diffusion
Ch. 8.7 Transport across Cell
Membrane
Oct. 23
Last Day to drop with a W
Homework Ch. 8 Due
Ch. 9.6 pKa
Ch. 9.7 Amino Acids
Ch. 9.8 Buffers and Blood
Oct. 30
EXAM 3
Chapters 7,8, and 9
Ch. 10.1 Amino Acids
Ch. 10.2 Protein Formation
Ch. 10.3 3-D Structure of
Proteins
Ch. 10.4 Denaturation for
Proteins
Ch. 10.5 Protein Functions
Nov. 6
Nov. 11
Quiz 10
Ch. 11.5 Genetic Code and
Protein Synthesis
Ch. 11.6 Genetic Mutations
Ch. 11.7 Viruses
Ch. 11.8 Recombinant DNA
Technology
Nov. 13
Nov. 18
Homework Ch. 11 Due
Ch. 12.6 Electron Transport
and Oxidative
Phosphorylation
Ch. 12.7 ATP Production
Ch. 12.8 Other Fuel Choices
Review for Exam 4
Nov. 20
Ch. 10.6 Enzymes
Ch. 10.7 Factors that Affect
Enzyme Activity
Ch. 11.1 Components of
Nucleic Acids
Ch. 11.2 Nucleic Acid
Formation
Ch. 11.3 DNA
Ch. 11.4 RNA and Protein
Synthesis
Quiz 11
Homework Ch. 10 Due
Ch. 12.1 Metabolism
Ch. 12.2 Metabolically
Relevant Nucleotides
Ch. 12.3 Digestion
Ch. 12.4 Glycolysis
Ch. 12.5 The Citric Acid Cycle
Quiz 12
Homework Ch. 12 Due
Exam 4
Oct. 28
Nov. 25
Dec. 2
Dec. 9
Thanksgiving
Review for Final
FINALS
4MW: 1pm-3pm
Nov.27
Dec. 4
Dec. 11
Thanksgiving
Finals
May 16
(THURSDAY)
Grades Due 9:00 am