Microbiology 1 (MICR V01)
Summer 2010
Sec. 50284
Lecture: Dr. Marta D. de Jesus (Ph.D.)
TuWTh 3:00 - 5:50 PM (SCI-313)
Lab: Prof. Eden Bellenson
TuWTh 12:00 - 2:50 PM (SCI-311)
Please pick up all handouts.
Introduction
What is MICR V01?
Nuts & bolts
Roll
Syllabus
Comments
Helps & Hints
College Website
http://www.venturacollege.edu
Your District Website:
http://my.vcccd.edu
Course Syllabus
A. COURSE DESCRIPTION
B. METHOD OF INSTRUCTION
C. STUDENT LEARNING OBJECTIVES
D. COURSE OBJECTIVES
E. COURSE TOPICS/UNITS
F. CORE COMPETENCIES
G. TEXTBOOK(S) AND REQUIRED SUPPLIES
Who is this class for?
Nursing: RN and beyond (BSN, MSN, PhD)
other pre-health: PharmD, OD, PA, etc. (possibly
DVM)
other interests (bioengineering, chemical
engineering, biotechnology, etc.)
Note: not usually recommended for MD or DO (not
accepted as units by medical schools in general) or
Microbiology majors.
Pre-requisites for Microbiology
CHEM V20 & V20L/V30 or V30 L/V 01 & V01L (requires beg. algebra) AND
PHSO V01 (requires ANAT V01 which requires BIOLV 01 & V01L) or BIOL V04
What topics did you get from those courses that you will use here?
Scientific method Metric system & conversions Subatomic particles, periodic
table, element descriptions , chemical symbols & formulas
Acids, bases/alkalis
& buffers
Basic microscopy Prokaryotic & eukaryotic cells (plant & animal) Cell division
Biological molecules (carbohydrates, lipids, proteins, nucleic acids)
Basic enzyme function DNA replication, RNA transcription & protein synthesis
Glycolysis, aerobic respiration, photosynthesis
Basic taxonomy
Human anatomy & physiology (including an intro to the immune system)
If you don’t remember or are shaky on a number of these, this class
will be very difficult.
Textbook
Also available:
1) CD-ROM & access to
microbiologyplace
website (comes with
new texts or go to
publisher website to
purchase)
2) Study Guide
(optional)
Course Syllabus
H. GRADING PLAN (p3)
(lecture %).75 + (lab %).25 = final %
Guaranteed grades
90-100% -> A
80-89% -> B
70-79% -> C
60-69% -> D
Below -> F
Course Syllabus
I. COURSE COMPONENT SPECIFICS
Quizzes: 10% (daily)
Lecture Tests: 40% (weekly)
Lecture Final: 25%
Please sit in the front half of the classroom for these
Lab: 25%
For Tests:
883
For Quizzes:
815
For Final Exam:
886
Course Syllabus
J. CLASSROOM RULES OF CONDUCT
http://www.venturacollege.edu/honesty/
1) Academic Dishonesty
2) Disruption/Obstruction of class
K. Some of the On-Campus Student Help
pg 29 & 49 Sched. Of Classes
http://www.assist.org
L. EMERGENCY PROCEDURES
Course Syllabus
M. Other miscellaneous helps
DISCLAIMER
Bloom’s Taxonomy (types of questions on college exams) p7
N. PLANNED SCHEDULE
AFFIDAVIT & Student Information Sheet - due tomorrow
Introduction
What is MICR V01?
Nuts & bolts
Roll
Syllabus
Comments
Helps & Hints
Learning preferences/styles - 4 popular models
VA(R)K
(sensory)
Sternberg
Kolb
So what works? Everyone can/does use these different modes
Dale’s
Cone of
Experiencethe more
you’re
involved,
the more
you get
Guaranteed: S+Q+3R+P
Method of Studying
Survey
Question
Read
Recite
Review
Hitch?
Practice
Introduction
What is Microbiology?
Microbes are:
1. small
Microbes are:
1. small
Microbes are:
1. small
16,600x
(when image is
2 in x 2 in)
Microbes are:
1. small
2. ubiquitous
Microbes are:
1. small
2. ubiquitous
3. ecologically important
Microbes are:
1. small
2. ubiquitous
3. ecologically important
4. medically important
antibiotics
trypanosomes
Microbes are:
1. small
2. ubiquitous
3. ecologically
important
4. medically
important
5. economically
important
Microbes are:
1. small
2. ubiquitous
3. ecologically important
4. medically important
5. economically important
6. often beneficial
probiotics
bioremediation
(algology)
(All kingdoms
except plants)
(More general: protistology)
(molecular biology)
& microbial ecology
What is Science?
sciens (Latin)
1. process/method
What is Science?
sciens (Latin)
1. process/method
2. information
What is not Science? examples
Art
Literature
Philosophy
Theology/Religion
(and some subjects are in between…)
Scientific Method
In every experiment should have 2 groups:
experimental
control
In lab, sometimes have 2 kinds of controls:
positive
negative
Big Moments in the History of Microbiology
A. Diseases & microbes
1. ancient explanations, transmission
2. fermentation
3. spontaneous generation disproved (Aristotle, Redi, Needham,
Spallanzani, Pasteur)
4. (in)famous diseases
a. Plague of Athens (430-25 B.C.E)
b. Black Plague (1348- outbreaks until 16th Cent. )
c. syphilis (~1500?)
d. Spanish Flu (1918)
e. HIV -> AIDS (late 20th Cent.-?)
People from text (before 1850)
Robert Hooke (1665)
Antoni von Leeuwenhoek (1674)
Francesco Redi (1668)
Carolus Linnaeus (= Carl von Linne; 1735)
John Needham (1745)
Lazzaro Spallanzani (1765)
Edward Jenner (1789)
Theodor Schwann & Matthei Schleiden (1839)
Ignaz Semmelweiss (1844)
After ~1855: Golden Age of Microbiology (some say 1857-1914)
Florence Nightingale (1854-6)
Walter Reed (1900)
John Snow (1854)
Paul Ehrlich (1908)
Rudolf Virchow (1858)
Emil von Behring & Shibasaburo Kitasato
*Louis Pasteur (1857)*
Albert Kluyver & C. B. van Niel
Sergei Winogradsky (1885-8)
Alexander Fleming (1928)
Eduard Buchner (1897)
Gerhard Domagk (1935)
Joseph Lister (1865) Oswald Avery/Colin MacLeod/Maclyn McCarty (1944)
*Robert Koch (1876)*
George Beadle & Edward Tatum (1958)
Charles Laveran (1880)
Linus Pauling (1965)
Christian Gram (1884)
Carl Woese (1977)
Julius Richard Petri (1887)
Dmitri Iwanoski (1892)
Martinus Beijerink (1898)
http://www.microbeworld.org/index.php?option=com_conte
nt&view=category&layout=blog&id=64&Itemid=61
The 1950’s: electron microscopes
TEM
SEM
Emerging & re-emerging infectious diseases (EIDs)
http://www.niaid.nih.gov/topics/emerging/pages/list.aspx
Are we in the 2nd Golden Age of Microbiology?
Many say “yes”
- Most of modern biotechnology uses microbiology or
techniques first developed with microbes.
- We know more about microbes now than ever before &
the information is accelerating…
Example: We now know the entire DNA coding for more than
many different bacterial species & more are being added all the
time.
The first bacteria to be completely DNA sequenced was Haemophilus
influenzae (1995, after many years of work). We now have labs that
complete equivalent work in a few months (note: making a vaccine or
drug takes far, far longer).