IAEA Standard Syllabus Course on Radiation Protection in Diagnostic and Interventional Radiology RADIATION PROTECTION IN DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY L 0. Principles of Radiation Protection and Motivation for the Course IAEA International Atomic Energy Agency Introduction • Subject matter motivation for radioprotection and quality assurance in diagnostic and interventional radiology • Give an overview of different contributions of radiation exposure, the principles of radiation protection • Specifity of the medical exposure IAEA Introduction to Radiation Protection in Diagnostic Radiology 2 Is there RADIATION in this room? IAEA Introduction to Radiation Protection in Diagnostic Radiology 3 Radiation - We live with Natural Radiation: Cosmic rays, radiation within our body, in food we eat, water we drink, house we live in, lawn, building material etc. Human Body: K-40, Ra-226, Ra-228 e.g. a man with 70 kg wt. 140 gm of K 140 x 0.012%= 0.0168 gm of K-40 0.1 Ci of K-40 24,000 photons emitted/min (T1/2 of K-40 = 1.3 billion yrs) IAEA Introduction to Radiation Protection in Diagnostic Radiology 4 K-40 Estimate for Lean Body Mass • Body weight = Fat + lean body mass • K-40 directly related to lean body mass • Whole body counter used IAEA Introduction to Radiation Protection in Diagnostic Radiology 5 Radiation - We live with Earth: Top 1m of 0.1 acre garden =1200 kg of K of which K-40 =1.28 Kg = +3.6 Kg of Th + 1 Kg Ur μGy/yr New Delhi, India 700 Bangalore, India 825 Bombay, India 424 Kerala, India (in narrow Coastal strip) 4000 Ramsar, Iran 10000 Guarapari, Brazil 8760 IAEA Introduction to Radiation Protection in Diagnostic Radiology 6 Radiation - We live with Food Radioactive levels (Bq/kg) Daily intake (g/d) Rice Wheat Pulses Ra-226 Th-228 Pb-210 K-40 150 270 60 0.126 0.296 0.233 0.267 0.270 0.093 0.133 0.133 0.115 62.4 142.2 397.0 Other Vegetables 70 0.126 0.167 -- 135.2 Leafy Vegetables 15 0.267 0.326 -- 89.1 Milk 90 -- -- -- 38.1 1370 0.067 0.089 0.063 65.0 Composite Diet IAEA Dose equivalent=0.315 mSv/yr Total dose from Natural sources = 1.0 to 3.0 mSv/yr Introduction to Radiation Protection in Diagnostic Radiology 8 Radiation from Natural Sources • Normally 1-3 mSv/year • In areas of high background, 3-13 mSv/year IAEA Introduction to Radiation Protection in Diagnostic Radiology 9 DO WE NEED RADIATION PROTECTION ? IAEA Introduction to Radiation Protection in Diagnostic Radiology 10 Drinking Hot Coffee Excess Temperature = 60º - 37 = 23º 1 sip = 3ml 3x 23 = 69 calories IAEA Introduction to Radiation Protection in Diagnostic Radiology 11 Lethal Dose= 4Gy LD 50/60 = 4 Gy For man of 70 kg Energy absorbed = 4 x 70 = 280 Joules = 280/418= 67 calories = 1 sip IAEA Introduction to Radiation Protection in Diagnostic Radiology 12 IAEA Introduction to Radiation Protection in Diagnostic Radiology 14 SO WE NEED RADIATION PROTECTION IAEA Introduction to Radiation Protection in Diagnostic Radiology 15 Radiation We live with 1-3 mSv Can kill 4000 mSv Where to stop, where is the safe point? What are the effects of radiation? IAEA Introduction to Radiation Protection in Diagnostic Radiology 16 What can radiation do? Death Cancer Skin Burns Cataract Infertility Genetic effects IAEA Introduction to Radiation Protection in Diagnostic Radiology 17 CAN X RAYS CAUSE DEATH? IAEA Introduction to Radiation Protection in Diagnostic Radiology 18 Effect Deterministic effects Cataract infertility erythema epilation Dose 500 mSv cataract 150 mSv for sterility (temporary-males) 2500 mSv for ovarian IAEA Introduction to Radiation Protection in Diagnostic Radiology 19 OBJECTIVES OF RADIATION PROTECTION • PREVENTION of deterministic effect • LIMITING the probability of stochastic effect HOW? Up to what point? IAEA Introduction to Radiation Protection in Diagnostic Radiology 20 Optimization • Optimization balances diagnostic image quality with dose to the patient. • High dose >> High image quality • Low dose may imply low image quality • However, there are a range of doses where image quality is clinically acceptable– want to be in that range IAEA Introduction to Radiation Protection in Diagnostic Radiology 21 Optimizaiton • Optimization is not ALARA • A certain amount of radiation is needed to provide the clinical image quality necessary for diagnostic purposes IAEA Introduction to Radiation Protection in Diagnostic Radiology 22 Which Exposure is Optimum? 6.0 mGy 1.5 mGy IAEA 3.0 mGy 0.6 mGy Little difference in noise between 6 and 3 mGy, therefore 6 mGy is too high. 0.6 mGy too noisy. Optimum between 1.5 and 3.0 mGy. Introduction to Radiation Protection in Diagnostic Radiology 23 OPTIMIZATION principle To what extent OPTIMIZATION ? Over-stretching OPTIMIZA …………………… TION IAEA Introduction to Radiation Protection in Diagnostic Radiology 24 Features of some epidemiological studies of radiation-induced cancer risks Life Span Study (LSS) of Japanese atomic bomb survivors Parameter (Shimizu et al) Massachusetts Ankylosing tuberculosis patients Spondylitis given chest Study (ASS) fluoroscopies (Weiss et al) (Boice et al) Children in Israel irradiated for ringworm of the scalp (Ron et al) UK National Registry for Radiation Workers (Kendall et al) Population 75991 14109 size (with DS86 doses) 2573 10834 95217 Period of 5-55 years Up to over follow-up following exposure 50 years (mean 25.2 years) Up to over 50 years Up to 32 years Up to 40 years (mean 30 years) (mean 26 years) Under 15 to over 40 0-15 years Ranges of: (a) ages at All exposure (b) sexes Similar numbers of males and females © ethnic Japanese groups Setting in War which exposure IAEA was received Virtually all 15 years 83.5% male 18-64 years Female Similar number of 92% male males and females Western (UK) Western (N. American) African and Asian Western (UK) Medical:ther- Medical:diagnostic Medical:therapy Occupational apy for nonfor non-malignant malignant disease Introduction to Radiation Protection in Diagnostic Radiology disease 25 Features of some epidemiological studies of radiation-induced cancer risks (cont.) Parameter Range of organs irradiated Life Span Study (LSS) of Japanese atomic bomb survivors (Shimizu et al) Massachusetts Ankylosing tuberculosis patients Spondylitis given chest Study (ASS) fluoroscopies (Weiss et al) (Boice et al) Children in Israel irradiated for ringworm of the scalp (Ron et al) All All (but mainly those in proximity to spine mainly brain, bone marrow, thyroid, skin and breast All Brain, thyroid & skin doses: individual basis Individual whole-body external doses Brain: 0-6 Gy (mean 1.5 Gy) Thyroid:0-0.5 Gy (mean 0.09 Gy) High Mainly 0-0.5 Sv (mean 0.034 Sv) Low Low-LET Mainly low-LET Mainly breast & lung Availability Organ doses: Mean organ Organ doses: of dose individual basis doses: indiv. Individual basis estimates only for red bone marrow at present Range dose Mainly 0-4 Gy Mainly 0-20 Gy Mainly 0-3 Gy Dose rate High Radiation Quality Mainly low-LET Low-LET IAEA High High, but highly fractionated Low-LET Introduction to Radiation Protection in Diagnostic Radiology UK National Registry for Radiation Workers (Kendall et al) 26 Dose Limits (ICRP 60) Effective dose Annual equivalent dose to • Lens of eye • Skin • Hands & Feet Occupational Public 20 mSv/yr averaged* over 5 yrs. 1 mSv in a yr 150 mSv1 500 mSv 500 mSv 15 mSv 50 mSv * with further provision that dose in any single yr > 30 mSv (AERB) and =50 mSv (ICRP) N.B.: M.P.D. 1931 = 500 mSv, 1947=150 mSv, 1977=50 mSv & in 1990=20 mSvICRP 1In a statement (Statement on Tissue Reactions Approved by the Commission on April 21, 2011) proposed a limit of 20 mSv/yr, averaged over 5 years, not exceeding 50 mSv at any single year . IAEA Introduction to Radiation Protection in Diagnostic Radiology 27 Changes in Dose Limit (ICRP) (Safe levels) mSv 500 400 300 200 100 0 1931 IAEA 1947 1977 1990 Year Introduction to Radiation Protection in Diagnostic Radiology 28 WHAT IS BASIS FOR DOSE LIMITS? IAEA Introduction to Radiation Protection in Diagnostic Radiology 29 Epidemiological studies have proven that there is an increased risk for cancer following exposure to radiation IAEA Introduction to Radiation Protection in Diagnostic Radiology 30 WHY REDUCTION IN DOSE LIMITS? IAEA Introduction to Radiation Protection in Diagnostic Radiology 31 PRINCIPLES OF RADIATION PROTECTION IAEA Introduction to Radiation Protection in Diagnostic Radiology 32 1. Justification of practices 2. Optimization of protection by keeping exposure as low as reasonably achievable 3. Dose limits for occupational IAEA Introduction to Radiation Protection in Diagnostic Radiology 33 HOW TO APPLY THESE PRINCIPLES IN DIAGNOSTIC RADIOLOGY? IAEA Introduction to Radiation Protection in Diagnostic Radiology 34 RADIOGRAPHY How much time one works with radiation? IAEA Introduction to Radiation Protection in Diagnostic Radiology 35 Radiation ON Time Workload=100 exposures/day CxR = 50x50 m sec = 2500 = 2.5 LS = 50x800 m sec = 40000=40s Total time = 45 sec/day Not greater than 1 min/day IAEA Introduction to Radiation Protection in Diagnostic Radiology 36 Staff Doses Dose limit ICRP = 20 mSv/yr. Radiography work 0.1 mS/yr. i.e. 1/200th of dose limit IAEA Introduction to Radiation Protection in Diagnostic Radiology 37 Radiation Doses in Radiological Exam. (as multiple of chest X ray) mSv .05 0.15 0.49 0.92 1.0 1.22 1.4 1.5 1.7 2.15 2.59 3.0 3.61 3.67 3.8 4.0 4.36 6.0 6.8 7.13 7.69 9.0 Relative Dose Received Arm, head,ankle & foot (1) Head & Neck (3) Head CT (10) Thoracic Spine (18) Mammography, Cystography (20) Pelvis (24) Abdomen, Hip, Upper & lower femur (28) Ba Swallow (30) Obsteric abdomen (34) Lumbo-sacral area (43) Cholangiography (52) Lumber Myelography (60) Lower abdomen CT male (72) Upper Abdomen CT (73) Ba Meal (76) Angio-head, Angio-peripheral (80) Urography (87) Angio-abdominal (120) Chest CT (136) Lower Abd. CT fem. (142) Ba enema (154) Lymphan. (180) 0 IAEA 50 100 number of chest X rays 150 Introduction to Radiation Protection in Diagnostic Radiology 200 38 IS IT POSSIBLE TO GET DETERMINISTIC EFFECTS IN RADIOGRAPHIC WORK ? For staff, for patient..?? IAEA Introduction to Radiation Protection in Diagnostic Radiology 39 Radiography Risk of Death Skin burn Infertility Cataract Cancer Genetic effect Staff No No No No U U Patient No No No No U U Public No No No No U U U: unlikely IAEA Introduction to Radiation Protection in Diagnostic Radiology 40 FLUOROSCOPY AND CT IAEA Introduction to Radiation Protection in Diagnostic Radiology 41 Fluoroscopy and CT Barium study: 3-6 min/pt x 8 patients/d =40 min/d ANGIOGRAPHY • Diagnostic = 50 min/d • Therapeutic = 2-5 hr/d CT = 10-45 min/d IAEA Introduction to Radiation Protection in Diagnostic Radiology 42 Fluoroscopy (excl. inv angio) Risk of Death Skin burn Infertility Cataract Cancer Genetic effect Staff No No No No U U Patient No No No No U U Public No No No No U U U: unlikely IAEA Introduction to Radiation Protection in Diagnostic Radiology 43 Summary 1. 2. 3. 4. 5. 6. Radiation we live with Radiation that can be lethal Radiation effects Dose limits Principles of protection Application of protection principles in diagnostic radiology IAEA Introduction to Radiation Protection in Diagnostic Radiology 44