Utah P41 Renewal Site Visit 2015 Introduction Schedule Start End Dur Topic 8:00 8:15 15 Shuttle to Campus 8:15 8:30 15 Continental Breakfast 8:30 8:40 10 Motivation and Goals of the Center 8:40 8:50 10 Comments and Feedback 8:50 9:00 10 Image Processing and Geometric Analysis 9:00 9:10 10 Comments and Feedback 9:10 9:20 10 Visualization 9:20 9:30 10 Comments and Feedback 9:30 9:40 10 Simulation and Estimation 9:40 9:50 10 Comments and Feedback 9:50 10:00 10 Collaboration and Service 10:00 10:10 10 Comments and Feedback 10:10 10:25 15 Break 10:25 10:35 10 Infrastructure 10:35 10:45 10 Comments and Feedback 10:45 10:55 10 Training, Dissemination, and Administration 10:55 11:05 10 Comments and Feedback 11:05 12:05 60 Posters and Demos 12:05 13:05 60 Lunch 13:05 13:10 5 DBP Intro 13:10 13:20 10 Comments and Feedback 13:20 13:30 10 DBP Example: Microscopy 13:30 13:40 10 DBP Example: Cardiac Arrhythmias 13:40 13:50 10 DBP Example: Biomechanics and Blood Flow 13:50 14:00 10 DBP Example: Neural Modulation 14:00 14:20 20 Comments and Feedback 14:20 15:00 40 Exec Meeting 15:00 16:00 60 Discussion with PIs 17:30 19:30 120 Optional Pub DInner Introduction Presenter(s) EAB Members EAB Members Chris J EAB Members Ross EAB Members Chris J (Chuck Hansen) EAB Members Dana (Rob and Chris Butson) EAB Members Rob EAB Members All Liz EAB Members Greg EAB Members All Rob EAB Members Liz/Rob for Rai Winslow, PhD Rob for Nassir Marrouche, MD Ross for Jeff Weiss, PhD Chris B for Kelly Foote, MD EAB Members EAB Members All Center Strategy Introduction Center History Introduction Center for Bioelectric Field Modeling, Simulation and Visualization established in 1999. Renewed as the Center for Integrative Biomedical Computing (CIBC) established in October 2005. Submitted Renewal in September 2009 (end date is July 31, 2010) Renewed until July 31, 2015 Center Moves to NIGMS in 2012 New Program Officer – Fred Friedman Center Renewal Proposal – September 25, 2014 Center Renewal Site Visit – February 18, 2015 Center Impact Introduction NIH/NCRR Center Awarded for 3 years. Sept, 1999 NIH/NCRR Center Renewal for 3 years. Sept, 2002 46 Publications First Workshop map3d v3.0 - 6.2 BioPSE/SCIRun v1.0.0 - v1.6.0 NIH/NCRR CIBC Renewal for 5 years Feb. 2005 49 Publications Second Workshop map3d v6.4 - 6.5 BioPSE/SCIRun v1.20.0 First release: BioFEM BioTensor BioImage NIH/NCRR CIBC Renewal for 5 years, July 2010 159 Publications 5 Workshops BioPSE/SCIRun v1.20.0 - v4.2 BioFEM BioTensor BioImage New BioMesh3D map3d v6.4 - 6.5 ImageVis3D v1.0 Seg3D v1.12 ShapeWorks 2015 132 Publications 13 Workshops NIH/BTR Portal BioPSE/SCIRun v4.2 - v4.7 SCIRun v5.0 alpha BioMesh3D BioMesh3D Client v1.0 BrainStimulator Forward/Inverse Toolkit map3d v7.1 ImageVis3D v2.0.1 - v3.1 Seg3D v2.15 ShapeWorks v0.3.0 - v1.2 Cleaver v2.0 Research Impact Introduction Software – Downloads >165,000 Total&downloads Downloads&in&2014 44,531&(since&2004) 3,372 44,436&(since&2007) 5,724 27,077&(since&2008) 4,981 Mobile&(App&Store)&&40,795& (since&2009) 7,040 7,799 790 3,625&(since&2009) 475&(w/o&NITRC&dowloads) Introduction Software Wikipedia Pages Introduction Software Videos Introduction http://vimeo.com/85177018 CIBC Software Development Introduction Training Impact: Since 2005 Postdoctoral Fellows: Introduction • Jeroen Sinstra—Research Staff Scientist, Numira Biosciences, Inc. • Xavier Tricoche—Associate Professor, Computer Science, Purdue University • Jens Krueger—Professor of Computing Science, University of Duisberg • Josh Levine—Assistant Professor of Computing Science, Clemson University • Erik Anderson—Research Scientist, EGI Graduate Students—Ph.D.: • • • • • • • • • • • • • • Seok Lew—Massachusetts General Hospital, Dept. of Radiology Fangxiang Jiao – TGS Burak Erem – Postdoc, Boston Children’s Hospital Suyash Awaite - Assistant Professor in the Department of Computer Science and Engineering at the Indian Institute of Technology, Bombay. Dafang Wang – Post Doctoral Fellow, Johns Hopkins University Sarah Geneser—Post Doctoral Fellow, Stanford University Alireza Ghodrati—Biomedian LLC Saeed Babaeizadeh—Phillips Medical Miriah Meyer—Post Doctoral Fellow, Harvard University, Assistant Professor of Computer Science and SCI Institute Jason Shepherd—Sandia National Laboratory Chris Butson—Associate Professor, University of Utah Sila Kurugol - Postdoc at BWH Josh Cates—Research Staff CARMA Darrell Swenson – L3 Training Impact (Cont.) Introduction Graduate Students—M.S.: • • • • • • Anastasia Mironova—Conoco Phillips Lee Roy Myers—Instructor, Eastern Wyoming College P.J. Hawkes—Medical School, University of Utah J.R. Blackham—Apple Computer Andrew Keely—Nuance Communications Jaume Coll Font – Ph.D. student at NEU (CIBC Supported) Undergraduate Students: • McKay Davis—Makai Ocean Engineering, Waimanalo, Hawaii • Zachary Warnock—Medical School, University of Utah • Lindsey Healy—Graduate Student, Bioengineering, Univ. of Utah • Patrick Rasch • Anatoliy Zharkikh • Cory Shirts Summary of Center Impact Assessment Introduction - Technology development/algorithms • Papers published • Citations to papers - Software/dissemination • New software products • Software releases • Downloads and citations/acknowledgements - Scientific Impact • Scientific results from DBPs (enabled by TRD) • Training- Graduate students/fellows- Tutorials and workshops - Mechanisms - Weekly CIBC Executive Meetings - Weekly Software Design and Evaluation Meetings - Annual External Advisory Board Meetings Center Vision Introduction Center Vision Introduction Center Vision Introduction Biomedical Research Clusters Introduction Driving Biological Partners Introduction Microscopy and Small Scale Imaging: Rai Winslow, PhD, John’s Hopkins University, Microscopy and Small Scale Imaging: Gabrielle Kardon, PhD, University of Utah, Biomechanics and Blood Flow: Alison Marsden, PhD, University of California, San Diego, Biomechanics and Blood Flow: Jeffrey Weiss PhD, Andrew Anderson PhD, University of Utah, Statistical and Biomechanical Analysis of Hip Dysplasia Driving Biological Partners Introduction Neuromodulation and Brain Source Localization, Don Tucker, PhD, University of Oregon and EGI Neuromodulation and Brain Source Localization, Michael Okun, MD and Kelly Foote, MD, University of Florida Cardiac Arrhythmias and Ischemia: Natalia Trayanova, PhD, John’s Hopkins University, Simulation of Cardiac Deļ¬brillation Cardiac Arrhythmias and Ischemia: Nassir Marrouche MD, University of Utah, Imagebased Management of Atrial Fibrillation Center Impact Introduction SINCE OUR LAST RENEWAL IN 2009: NIH/NIGMS CIBC Renewal, 2009 Software Impact • Over 15,000 downloads of SCIRun, (all from outside the Center and our affiliate institutions) • Over 15,000 downloads of Seg3D, • Over 7000 downloads of the CIBC data sets. • Over 23,800 downloads of ImageVis3D and ImageVis3D Mobile. (Average 250% increase in software downloads) Publication Impact • Over 300 papers published by scientists outside the Center referencing CIBC software (33% increase) • Center members have authored over 140 publications related to biomedical computing in a wide range of technical and biomedical journals and conference proceedings. 2015 Schedule Start End Dur Topic 8:00 8:15 15 Shuttle to Campus 8:15 8:30 15 Continental Breakfast 8:30 8:40 10 Motivation and Goals of the Center 8:40 8:50 10 Comments and Feedback 8:50 9:00 10 Image Processing and Geometric Analysis 9:00 9:10 10 Comments and Feedback 9:10 9:20 10 Visualization 9:20 9:30 10 Comments and Feedback 9:30 9:40 10 Simulation and Estimation 9:40 9:50 10 Comments and Feedback 9:50 10:00 10 Collaboration and Service 10:00 10:10 10 Comments and Feedback 10:10 10:25 15 Break 10:25 10:35 10 Infrastructure 10:35 10:45 10 Comments and Feedback 10:45 10:55 10 Training, Dissemination, and Administration 10:55 11:05 10 Comments and Feedback 11:05 12:05 60 Posters and Demos 12:05 13:05 60 Lunch 13:05 13:10 5 DBP Intro 13:10 13:20 10 Comments and Feedback 13:20 13:30 10 DBP Example: Microscopy 13:30 13:40 10 DBP Example: Cardiac Arrhythmias 13:40 13:50 10 DBP Example: Biomechanics and Blood Flow 13:50 14:00 10 DBP Example: Neural Modulation 14:00 14:20 20 Comments and Feedback 14:20 15:00 40 Exec Meeting 15:00 16:00 60 Discussion with PIs 17:30 19:30 120 Optional Pub DInner Introduction Presenter(s) EAB Members EAB Members Chris J EAB Members Ross EAB Members Chris J (Chuck Hansen) EAB Members Dana (Rob and Chris Butson) EAB Members Rob EAB Members All Liz EAB Members Greg EAB Members All Rob EAB Members Liz/Rob for Rai Winslow, PhD Rob for Nassir Marrouche, MD Ross for Jeff Weiss, PhD Chris B for Kelly Foote, MD EAB Members EAB Members All