None-urgent eye problems David Kinshuck, associate specialist David Kinshuck, Good Hope Hospital, None-urgent eye problems …working in pairs, (1 minute) write down • Common conditions • Rarer & serious conditions Draw an eye and name the parts…working in pairs, (30 s) : • parts • Parts relevant to conditions www.websightmd.com www.websightmd.com Aqueous flow Chronic eye conditions Adults cataracts Armd...age-related macular degeneration Glaucoma Diabetic retinopathy Others (retinal vein occlusion, inherited retina, corneal etc) children Squints Watery eye Cataracts Glaucoma rarer Cataracts Symptoms How to examine Operation refraction Cataracts symptoms, in pairs • ? • ? • ? • ? Cataracts symptoms Glare Misty vision Blurred vision Cannot see distances/faces Cataracts...symptoms....blurred Cataracts...symptoms....glare Examining for cataract…red reflex Looking through ophthalmoscope, check red reflex from 10 cm, focusing on iris rim ‘white’ reflex ?retinoblastoma www.occhioallaretina.it/Immagini/leucocoria.JPG http://oftalmologo.bravepages.com/Leucocoria%201.jpg Cataracts...operation Link http://www.goodhopeeyeclinic.org.uk/eye cataractpatient.html Cataracts...refraction...in pairs, which is myopia etc Cataracts...refraction – Emmetropia.. no dist. specs – Hypermetropia, small eyes – Myopia – High myopia Presbyopia...need reading spectacles, >45y Retina – Diabetic retinopathy – Retinal vein occlusion – Armd...age-related macular degeneration – Others • retinal vein occlusion • inherited retina (eg retinal pigmentosa) Diabetic retinopathy, in pairs, 45 seconds • What are the disease processes • What one chemical in particular mediates these processes (and we can block its effect) • What does laser do http://medweb.bham.ac.uk/easdec/dmret.html http://medweb.bham.ac.uk/easdec/mechanism animation.htm Diabetic retinopathy Diabetic retinopathy • dot and blot • ischaemic areas • VEGF • leakage • new vessels Diabetic retinopathy • dot and blot • ischaemic areas • VEGF • leakage • new vessels Diabetic retinopathy Diabetic retinopathy Diabetic retinopathy http://reference.medscape.com/features/slideshow/retina Diabetic retinopathy, in pairs, how do you prevent, 30s Diabetic retinopathy, in pairs, how do you prevent, 30s • Prevent diabetes…exercise, weight, low glycaemic index foods • Screen for diabetes…everyone >40y, high risk if lower (lifestyle/family etc), • HbA1c >6.5% = diabetes • HbA1c 6.0-6.5% = pre-diabetes • Control diabetes HbA1c <6.5-75, BP <130/80, statin, ARB • Screen diabetic patients for retinopathy • etc Diabetic retinopathy • • • • • HbA1c Blood pressure Smoking Lipids Duration of ‘high’ HbA1c similar for BP/smoking/lipids Retinal vein occlusion 7 highs • • • • • cigarettes Cholesterol Blood pressure Glucose Viscosity – Myeloma – White cells Macula..in pairs, 1 minute • • • • What do you know about armd Symptoms Types etc Macular Central visual changes suggest macula disease: Eye casualty same week Central vision OCT optical coherence tomogram … wet ARMD http://www.goodhopee yeclinic.org.uk/images /lucentis.html Dry, ‘geographic atrophy’ Areas of atrophy enlarge over a couple of years, seriously reducing central vision Glaucoma, in pairs, explain with diagram, 1 min Glaucoma, mechanism • Aqueous produced in ciliary body (carbonic anhydrase enzyme) • Flows into >anterior chamber, >through trabecular >meshwork, >canal of schlemm, >episcleral veins • > otherwise pressure Glaucoma, loss of visual field • Visual loss over years • 2/3 chronic glaucoma has a high pressure…pressure is detected by whom • A • B patient optometrist Glaucoma, loss of visual field • Visual loss over years • 2/3 chronic glaucoma has a high pressure…pressure is detected by whom • A • B patient optometrist Glaucoma, in pairs, which normal eye, 30s A B http://www.goodhopeeyeclinic.org.uk/glaucomacase3.htm Glaucoma, in pairs, which normal eye, 30s 1. Vessels deviated nasally 2. Pale central area with cribriform pits 3. thin rim 4. Other minor changes http://www.goodhopeeyeclinic.org.uk/glaucomacase3.htm Glaucoma, lowering pressure • Laser trabecular meshwork • Drops – Prostaglandin inhibitors – Carbonic anhydrase inhibitor – Betablockers • tablets – Carbonic anhydrase inhibitor • surgery Glaucoma, quiz • Patient detects glaucoma Y N Glaucoma, quiz • Are there symptoms early Y N Glaucoma, quiz • Examining the eye – Cupped disc Y N Glaucoma, quiz • Examining the eye – Raised pressure 66% Y N Glaucoma, quiz – Examine angle at onset Y N Glaucoma, quiz – Visual field Y N Glaucoma, other types – Yearly checks stable Y N Glaucoma, quiz • Patient detects glaucoma • Are there symptoms early • Examining the eye – Cupped disc – Raised pressure 66% – Examine angle at onset – Visual field – Yearly checks N N Y Y Y Y Y Glaucoma, other types • Low tension • Narrow angle http://www.goodhopeeyeclinic.org.uk/pi.html • Genetic – Many conditions – congenital baby • Secondary surgery/trauma/steroids Glaucoma, – Congenital (www.nature.com/eye) Loss of sight over weeks/days/hours • Retinal detachment, with flashes/floaters • Ischaemic optic neuropathy (older patients) (%GCA with GCA symptoms) • With pain on movement & reduced colour (red) vision: optic neuritis (younger patients) Retinal detachment 1. Vitreous gel liquifies (floaters) 2. May pull retina if attached (flashes) 3. Causes a hole 4. Fluid enters hole 5. Retina peels off (more floaters, vision affected) 6. Dilate pupil, with careful look usually obvious, refer same day Eye & major trauma Visual acuity T 6/60 NC 6/36 EN 6/24 OTNC 6/18 LOXEW 6/12 TYURNG 6/9 TYURNG TYURNG 6/6 6/5 Visual fields paper paper Pupils • Pupils (needs Flash player installed) Some helpful eye examination ‘pearls’ • Pressing on the eye will detect high pressure (acute glaucoma) • Won’t detect slightly high pressure chronic glaucoma • DILATE PUPILS to examine the eye if risk of detachment...cannot exclude detachment otherwise • Optometrists can check for chronic disease Children, chronic disease • Rare – Cataracts – Glaucoma – Lots • Common – – – – watery eyes (lacrimal sac abscess/mucocoel) Squints Allergic eye disease Children, chronic disease---watery eyes Children, squint Children, squint • Convergent • Divergent • vertical Children, squint, issues • Amblyopia – important to know this, as may spend lots of time looking for the cause of poor sight – Initially amblyopia need patching • Squint surgery • Binocular vision • amblyopia without squint may be refractive, cataract, etc Children, cover test • http://www.youtube.com/watch?v=yyIAdl49Lg In pairs...what is this? 3rd nerve palsy 3rd nerve palsy 3rd nerve palsy Other chronic eye diseases • • • • • • • • • • • • TED...thyroid eye disease Lid entropian/ectropian Trichiasis Eyelid tumours Watery eyes..epiphora Blocked naso-lacrimal duct Diplopia/squint Dry eyes Corneal diseases Optic atrophy, alcohol, smoking, B12 genetic Orbital/optic nerve tumours In pairs...what is this? 3rd nerve palsy www.patient.co.uk..thyroid eye disease 3rd nerve palsy www.patient.co.uk..thyroid eye disease 3rd nerve palsy Auto-immune +thyroid damage >> TRH receptors on muscles and fat in orbit Low TSH and smoking increase TRH receptors >> fat muscles swell >> exophthalmos + optic nerve compression In pairs...what is this? 3rd nerve palsy In pairs...what is this? nhs.uk 3rd nerve palsy In pairs...what is this? cosmeticsurg.com 3rd nerve palsy Dry eye • link • Mild forms very common, not serious, troublesome • Very dry, and dry mouth, ?Sjogrens • Very severe dry extremely uncommon: corneal melts and perforates..severe autoimmune disease Corneal disease • Lots of uncommon corneal diseases • In poor countries, trachoma >> corneal scarring • http://www.goodhopeeyeclinic.org.uk/fuchs .html • Dry eye trachoma Dry eyes http://www.goodhopeeyeclinic.org.uk/dryeye.html Dry eyes http://www.d ryeye.org/im ages/colorba r.jpg Fuchs corneal dystrophy etc •http://www.goodhopeeyeclinic.org.uk/fuchs.html •Keratoconus Optic atrophy • Low B12 • Secondary to retinal artery occlusion or ION • Tobacco alcohol amblyopia (vitamin B deficiency) Retinal dystrophy • http://geneticpeople.com/?tag=retinitispigmentosa Summary, go round the room 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. . . . . . . . . . . . . . . . . .