• acetyl-glutamyl-glutamyl-methyoxylglutaminylarginyl-arginylamide ( Argireline

) 在細胞外藉由影響
鈣離子調控的胞吐作用（ Calcium-dependent exocytosis ）所需的蛋白質生成，進而 抑制神經介質
的釋放 。藉由 減少肌肉收縮而減少細紋和皺紋
• SNARE complex 是膜上蛋白質調控神經胞吐作用的
核心，因為此一複合物會導致（ Catecholamine ）的
釋放，如果 Catecholamine 釋放太多就會導致皺紋以
及細紋的形成；所以此類的胜肽就是抑制 SNARE complex 生成

• EGF : Epidermal Growth Factor 表皮細胞生
長因子
– 刺激老化皮膚細胞再活化
– 刺激表皮細胞生長
– 刺激其他活細胞激素分泌
– 刺激纖維母細胞分泌膠原蛋白
及彈力蛋白
– 刺激受傷組織血管增生，加速
癒合
– 傷口癒合過程中防止疤痕形成
– 抗皺
• FGF: Fibroblast Growth Factor 纖維母細胞
生長因子
– 皮膚再生
– 刺激膠原蛋白及彈力蛋白合成
– 刺激纖維母細胞生長
– 刺激老化組織再生以及傷口癒
合
– 刺激表皮細胞生長及移動
– 刺激毛髮生長，防止白頭髮形
成
– 刺激玻尿酸合成
•
IGF: Insulin like Growth Factor 類胰島
素生長因子
– 扮演與生長荷爾蒙相同功能
– 刺激骨骼、肌肉及神經再生
– 刺激受傷組織血管增生
– 減緩腦下垂體老化
– 刺激玻尿酸合成
– 刺激毛髮生長並預防落髮
•
VEGF : Vascular Endothelial Growth
Factor 血管內皮細胞生長因子
– 血管內皮細胞生長因子是強力新
血管生長因子
– 刺激血管細胞增生
– 刺激血管細胞移動
• TGF-β3 : Transforming Growth Factor-
β3
– 多功能的細胞激素
– 刺激細胞繁殖、生長及分化
– 去除疤痕的形成
– 協助傷口癒合

•
– Titanium dioxide 、 Zinc oxide 、 Iron oxide
– Mica and other metal oxide
•
– Liposome and ethosome
– Nanosome and micelle
– Fullerene
•
– Mask containing chitin/chitosan fiber

Lindsay Elkins, Contributing Editor, December 2008
•
•

1. Unilever
2. L ’ Or é al
3. Henkel
4. Kao
5. Reckitt Benckiser
6. Beiersdorf
7. Shiseido
8. LVMH
9. Lion
10. Chanel
11. Yves Rocher
12. Natura
13. GlaxoSmithKline
14. AmorePacific
15. Kos é
2008
United Kingdom
France
Germany
Japan
United Kingdom
Germany
Japan
France
Japan
France
France
Brazil
United Kingdom
Korea
Japan
$25.48 billion
$23.3 billion
$9.75 billion
$9.6 billion
$9.42 billion
$6.38 billion
$6.35 billion
$3.74 billion
$2.65 billion
$2.5 billion
$2.41 billion
$2.2 billion
$2.1 billion
$1.78 billion
$1.58 billion

16. Clarins
17. Oriflame
18. LG
19. Puig
20. Pierre Fabre
21. YSL Beaut é
22. Pola
23. PZ Cussons
24. The Bolton Group
25. Sunstar
26. The Colomer Group
27. Mandom
28. Lornamead
29. Menard
30. Fancl
2008
France
Sweden
Korea
Spain
France
The Netherlands
Japan
United Kingdom
The Netherlands
Japan
Spain
Japan
United Kingdom
Japan
Japan
$1.38 billion
$1.37 billion
$1.26 billion
$1.21 billion
$1.0 billion
$889 million
$878 million
$828 million
$739 million
$637 million
$598 million
$556 million
$537 million
$521 million
$430 million

• Major Products:
– Personal care—Axe/Lynx, Rexona/Sure and Degree deodorants; Dove, Caress, Lux and Lifebuoy soaps;
Pond’s and Vaseline skin care products; Organics,
Salon Selectives, SunSilk, Suave and ThermaSilk hair care products; Close-up and Signal oral care products.
Household —Ala, All, Omo/Persil and Surf laundry detergents; Comfort and Snuggle fabric softeners;
Sunlight dish detergent, Domestos bleach, Cif cleaners.
• New Products:
– Vaseline Cocoa Butter range, Clear anti-dandruff shampoo, Domestos Zero Limescale bleach.

• Major Products:
– L’Oréal Paris, Garnier, Maybelline New York, SoftSheen Carson.
– L’Oréal Professionnel, Kérastase, Redken, Matrix, Mizani,
Pureology Luxury —Lancôme, Biotherm, Helena Rubinstein,
Kiehl’s, Shu Uemura, Giorgio Armani, Parfums Cacharel, Ralph
Lauren Fragrances, Paloma Picasso, Parfums Guy Laroche,
Diesel, Victor & Rolf, Yue-Sai. Active Cosmetics —Vichy, La
RochePosay, Skinceuticals, Sanoflore. L’Oréal’s operations also include The Body Shop and Galderma, and 50% stakes in Le Club des Créateurs de Beauté and Laboratoires Innéov.
• New Products:
– L’Oréal Professionnel Color Supreme, L’Oréal Professionnel
Homme Cover 5 grey hair cover, L’Oréal Paris Glam Shine,
Derma Genesis/Skin Genesis, Lancôme Rénergie Morpholift Rare line, L’Oréal Professionnel Age Densiforce, La Roche-Posay
Substiane anti-aging replenishing care, Maybelline Define-A-Lash,
Lancôme Virtuose mascara, Shu Uemura Art of Hair, Mizani Butter
Blend.

• Major Products:
– Laundry and home care sold under brands such as Persil, Purex,
Dixan, Vernal, Mir Colueurs, Pril, Bref, Spee Weißer, Riese and
Somat. Cosmetics and toiletry brands include Schwarzkopf, Fa,
Right Guard, Dial, Igora, Palette, Gliss, Kur, Schauma, Taft,
Theramed and Diadermine.
• New Products:
– Laundry— Purex Natural Elements, Persil 20 ° C formulation;
– Hair care— Palette Golden Gloss Browns, Gliss Kur Oil Nutritive,
Schuama Kiwi Glanz, Taft Volume Power, Drei Wetter Taft
Sensitive, BlondMe
– Personal care— Fa Naturals shower gel and deodorant, Dial
Yogurt; Skin care —Diadermine AgeExcellium
– Oral care—Theramed 2-in-1 freshness, Theramed Titan Fresh.

• Major Products:
– Household products, personal care products and color cosmetics.
• New Products:
– Sofina beauté, Sofina Primavista base makeup,
Asience hair care (relaunched globally), Megurism steam eye mask, Attack Biogel liquid laundry detergent, Men’s Biore line (relaunched in Japan).

• Major Products:
– Surface care— Cillit Bang, Lysol, Dettol, Harpic.
– Fabric care— Calgon, Vanish, Resolve, Spray ‘n
Wash, Woolite.
– Dishwashing— Finish, Electrasol
– Home care– Airwik, Mortein
– Health and Personal care— Veet, Dettols, Clearasil.
• New Products:
– Cillit Bang Grease & Floor, Dettol Herbal soap and shower gel, Veet Pump Pack, Mortein with Dettol,
Mortein Naturgard range, Airwick Freshmatic Mini.

• Major Products:
– Skin care, beauty care and toiletries sold under brand names that include Nivea, Eucerin, La Prairie, Slek,
Labello, 8x4, Florena.
• New Products:
– Nivea Diamond Gloss hair products; Nivea My
Silhouette body shaping gel; Nivea for Men Extreme
Comfort; Nivea For Men whitening oil control (India);
Nivea for Men DNAge anti-wrinkle moisturizer; Nivea
Good-Bye Cellulite dietary supplement capsules (U.S. only); Eucerin Hyaluron-Filler eye care.

• Major Products:
– Skin care, color cosmetics, sun care, fragrances, hair care and toiletries. Major brands include Shiseido, Carita, Decleor, IPSA,
Ettusais, D’icila Parfums Issey Miyake, Parfums Jean Paul
Gaultier, Parfums Narciso Rodriguez, Nars, Cle de Peau Beaute
Za, Parfums Serge Lutens, Urara and Supreme Aupres.
• New Products:
– Clé de Peau Beauté La Crèmes, Revital, Aqua Label skin care,
Acne& skin lightening series, Uno men’s skin care, Tsubaki
Golden Repair hair care, Urara Makeup, Shiseido BOP intensive skin collective program, Shiseido Zen fragrance (relaunch).

• Major Products:
– Fragrances and cosmetic sold under brands such as Christian Dior,
Guerlain, Givenchy, Kenzo, Acqua di Parma, Parfums Loewe, Benefit,
Fresh and Makeup Forever. LVMH also owns Sephora, the beauty products retailer.
• New Products:
– Dior— Fahrenheit 32 for men, Midnight Poison Addict Shine fragrances,
Capture L’ Ore de Vie, Diorskin foundation, Backstage.
– Guerlain— L’Instant Magic, Eau de Shalimar, Aqua Allegoria Figue Iris and
Aqua Allegoria Laurier Réglisse, Cruel Gardénia, Cherry Blossom delight,
My Insolence.
– Parfums Givenchy— Organza Jasmin 2007, Very Irresistible Rosa
Damascena 2007, Amarige Mimosa 2007, Vetyver, Rouge Interdit lipstick.
– Parfums Kenzo— Tokyo by Kenzo for men, Vintage Edition.
– Benefit— Love Your Look, That Gal face brightening primer.
– Makeup Forever— Aqua Eyes waterproof eyeliners.
– Acqua de Parma— Colonia Intensa.
– Parfums Loewe— Quizas, Quizas Quizas. Fendi Palazzo and Pucci Vivara fragrances.

• Major Products:
– Oral care (toothpastes, toothbrushes mouthwashes, breath fresheners, dental needs); beauty care (shampoos, conditioners, treatments, hair styling products, men’s hair care, soap, body washes, skin care, antiperspirants and deodorants); fabric care (laundry detergents and additives, bleaches, fabric softeners); home care (dishwashing detergents, disinfectants, household cleaners, kitchen-related products) and insecticides.
• New Products:
– Household— Soflan with Fragrance and Deodorant fabric softener, Top
Kaori Tsuzuku chamomile-scented liquid laundry detergent with fabric softener, Look O2 Cleaner (joint product with Henkel), Charmy gelbased dishwasher cleaner/detergent.
– Oral care— Dentor Systema EX Extra Herb, Medish oral care gum.
– Personal care— Ban Deodorant Mist, Ban Refresh Powder Sheets,
Bathology skin care, Pro Tec Head men’s hair care.

• Major Products:
– Skin care, color cosmetics and fine fragrances.
• New Products:
– Skin care— Sublimage Essential Regenerating Cream,
Hydramax + Active moisture tinted lotion SPF 15
– Color cosmetics— Facettes d’or nail color; Robertson
Boulevard limited edition nail collection
– Fragrance— Allure pour Homme Edition
Blanche, Chance Eau Fraîche, Allure Homme Sport
Cologne Sport, No. 5 Eau Première.

• Major Products:
– Skin care, cosmetics and fine fragrances marketed under the brand names of Yves Rocher, Daniel
Jouvance, Dr. Pierre Ricaud and Kiotis.
• New Products:
– Fragrance— Naturelle, Comme une évidence Homme.
– Personal care— Plaisirs Nature Kiwi eau de toilette and shower gel
– Skin care— Culture Bio.

• Major Products:
– Natura Ekos, Natura Tododia, Natura Chronos,
Natura Mamãe e Bebê, Natura Diversa, Natura Amor
América.
• New Products:
– Natura Amor América, Natura Naturé, Natura Tododia,
Natura Diversa Hidratação Prolongada, Natura
Chronos Politensor de Soja, Natura Aguas, Natura
Fixplant, Natura Faces, Natura Mamãe e Bebe,
Natura Ekos Cacau, Natura Homem Chromo, Natura
Erva Doce Hidratante Facial, Natura Crer Para Ver
Bolsa Amiga do Meio Ambiente.

•
– Toothpaste and mouthwash— Aquafresh, Dr.
Best, Macleans, Odol, Odol Med 2, Polident,
Polygrip, Sensodyne
– Denture care— Polident, Polygrip, Corega.
•
– Aquafresh iso-active foaming gel

• Major Products:
– Skin care and makeup— Laneige, Iope, Mamonde,
Innisfree, Hera, Lirikos.
– Fragrances— Lolita, Lempika, Castel Bajac, Espoir.
• New Products:
– Sulwhasoo su Essence, ioPE Whitegen RXC, V=B
Yeginseng, premium makeup from Laneige, Happy
Bath Blue Spa Essential Body Cleanser.

•
– Skin care, cosmetics and toiletries.
•
– Junkisui skin care.

•
– Skin care, fine fragrance, color cosmetics and sun care sold under brand names such as
Clarins, Thierry Mugler, Azzaro, Stella
Cadente and My Blend.
•
– My Blend customizable skin care

• Major Products:
– Skin care, fragrances, color cosmetics, toiletries and accessories.
• New Products:
– Enigma and Radiant Lights fragrances, Optimals
Radiance Glow self tanner, Lift Expert, Perfect Body,
Lash Extreme, Royal Velvet Intensive Revitalizing
Cloth Mask. Also, Diamond Musk, Silky Kiss lipstick,
Diamond Cellular Anti-aging cream and
Dermoprofessional Bio-Peeling Kit (all in September).

• Major Products:
– Household— laundry and dishwasher detergent, fabric softener, kitchen cleaners.
– Personal care— toothpaste, shampoo, soap, baby care, skin care, color cosmetics and toiletries.
• New Products:
– su:m 37 fermented cosmetics, Borrowing Earth household products.

• Major Products:
– Fragrances— Adolofo Dominguez, Agatha Ruíz de la Prada,
Ague Brava, Anouk, Antonio Banderas, Barbie, Carmen Sevilla,
Don Algodon, Maja, Mango, Massimo Dutti, Pachá, Quorom,
Roasiro Flores, Sportman, Victori & Lucchino, Zara, Boston Man,
1916, Antonio Miro, Azur de Puig, Brummel, Eau d’Ete, Equinox,
Farala, Springfield, Yacht Man Blue, Zinnia.
– Personal Care— Payot, Dennenes, Heno de Pravia, Lactovit,
Vitese, Kinesia, Maja, Agua Lavanda Puig, Maderas, Misslyn,
Nelia, VF.
• New Products:
– Blue Seduction for Women

• Major Products:
– Skin care and hair care products sold under the
Avéne, Ducray, Pierre Fabric Dermatologie, Klorane,
Galénic and Réne Furterer banners.
• Comments:
– Pierre Fabre’s Dermo-Cosmetics unit earmarks 5% of its sales for research projects, which are conducted at its centers in Vigoulet-Auzil and Saint-Jacques
Hospital in Toulouse. Research conducted in
Toulouse is made possible through an agreement between the Pierre Fabre group, the local university hospital and Toulouse University.

• Major Brands:
– Fragrances, cosmetics and skin care products. Brands include
Yves Saint Laurent, Roger & Gallet, Stella McCartney, Alexander
McQueen, Boucheron and Ermenegildo Zegna.
• New Products
– Fragrance— Yves Saint Laurent Elle, Paris Nuit de Fete, Paris
Pont des Amours, Opium Poesie de Chine Eaux d’Orient,
L’Homme Yves Saint Laurent Eau d’Été 2008, Elle Yves Saint
Laurent summer fragrance 2008, Cinéma Scénario d’été, Baby
Doll Magic; Ermenegildo Zegna Z Zegna Fresh; Stella
McCartney Stella Sheer 2008.
– Cosmetics—LipTwins.

• Major Products:
– Skin Care— Alvita, Whitissimo, Day + Day Vitax,
Botanex, 1/f, Plenna, Polissima, BA, Signs Solution
28 Carats, Signs Solution Wrinkle Shot, Evangile
– Cosmetics— Whitissimo, Silfique, Vivoke, Aniak,
Maquifard, Super Suncare, Southern Call
– Body Care— Feel & Heal; Hair Care—Idea Style,
Simfree Hair Color
– Men’s Care— Galantom, GR Shot S.
• New Products:
– Whitissimo base makeup.

• Major Products:
– Personal care products sold under brands including
Imperial Leather, Joy, Cussons Kids, Premier, Carex,
Baby, Luksja, Makler, Sweet Seventeen, Venus Hair,
Original Source. Household product brands including
Morning Fresh, Elephant, E, Radiant, Robb, Duck and
Minerva.
• New Products:
– Imperial Leather SkinBliss.

• Major Products:
– Laundry care products—Omino Bianco, Merito, Nibro
– Bathroom/kitchen care and cleaners—WC Net, Fornet, Last, Dubro,
Solivaisselle
– Surface & Floor Care—Carolin, SMAC, Overlay, Vetril, WC Eend
– Household soap products—Cyclon, D’orn. Personal Care—Neutro Roberts,
Borotalco, Rogé Cavaillès, Sanogyl, Somatoline, Roberts Fragrance,
Acque Alle Rose Robert, Citrosil, Botot, Wetties, Soapy, Silx
– Beauty—Collistar skin care, makeup, hair care.
• New Products:
– Collistar—Long Lasting Color Line and Nourishment and Lustre Lines for hair care, Body Energizing Treatment for men, Global Anti-Age Protection
Tanning Face Cream SPF 30-50+, Supertanning Moisturizing Dry Oil SPF
15, Sun Effect Make-Up line, Topgloss Stick Reflex, Magnifica Patch-
Lifting-Dermal Filling Repairing Face and Neck Mask, Perfecta Active Neck and Décolleté Cream, Magic Drops self-tanning concentrate, Brightening
Touch highlighting concealer, Eye Contour Lifting Treatment for men,
Perfect Adherence Shaving Foam, Moisturizing Soothing Sensitive Skins,
Perfect Adherence Shaving Foam, Moisturizing Softening Tough Beards,
Extreme Supermascara, Anti-Time 360 ° for Men. Rogé Cavaillès—
Dermatological Deo-Care deodorant.

•
– Oral care and beauty care products.

• Major Products:
– Hair and nail care products.
– Professional— Revlon Professional, Intercosmo, Modern
Organic Products, American Crew, D:FI, Creative Nail, Tigi
– Consumer— Fermodyl, Fixpray, Floïd, Geniol, Lanofil,
Llongueras, Natural Honey, Revlon Flex, ZP11
– Cosmetics— BioPoint, Burberry (license), Gatineau (license),
Revlon (license); St DuPont (license), Ultima II (license)
– Multicultural— African Pride, Arosci, Creme of Nature, Fabu-
Laxor, Revlon Realistics, Special Feeling.
• New Products:
– Crème of Nature—Red Clover and Aloe Daily Breakage Relief and Jojoba & Olive Oil Moisture Active Deep Conditioning treatment; African Pride —Miracle Deep Conditioning No Lye
Relaxer System with Healing & Hydrating African Herbs.

•
– Men’s toiletries—Gatsby and Lucido and
Women’s toiletries—Lucido L, Produce, Pixy and Simplity.

• Major Products:
– Hair care— Aqua Net, Finesse, Harmony, Lypsyl,
Vosene.
– Cosmetics and skin care— CD, Handsan, Tura.
Fragrance and bath —Woods of Windsor, Yardley.
– Oral Care– Brilliant, Rapid White.
• New Products:
– Vosene new shampoo range, Finesse revitalizing shampoo, LypSyl Beeswax lip balm.

•
– Skin care, cosmetics and fragrances.

•
– Cosmetics and skin care products sold under the Attenir, Fancl and Nicostar banners.
•
– Fancl Sunguard SPF 30.