Substrates for respiration. Starch and glycogen, other sugar molecules, amino acids and fats. Starch and glycogen are broken down to glucose for use as a respiratory substrate. Other sugar molecules can be converted to glucose or glycolysis intermediates for use as respiratory substrates. Respiratory substrates Carbohydrates Starch (storage carbohydrate in plants) and glycogen (storage carbohydrate in animals) are both complex molecules composed of glucose sub-units. They act as respiratory substrates since they can be broken down to glucose which is then used in respiration. Starch Maltose Glycogen Glucose Sucrose Fructose Other sugars like maltose and sucrose can be converted to glucose or intermediates in glycolysis and used as respiratory substrates Pyruvate Proteins can be broken down to amino acids and converted to intermediates of glycolysis and the citric acid cycle for use as respiratory substrates. Proteins Proteins in the diet are digested to their component amino acids. Excess amino acids undergo deamination in the liver. Deamination forms the waste product urea and also forms intermediates in the respiration reactions. These intermediates act as respiratory substrates in the pathway Glucose Diagram illustrates how some amino acid products enter the respiratory pathway and need not be memorised Amino acids e.g. alanine Protein urea Amino acids Pyruvate Acetyl coenzyme A e.g. leucine urea Amino acids e.g. aspartic acid intermediate urea Citric acid cycle Fats can also be broken down to intermediates of glycolysis and the citric acid cycle. Fats Fat is digested to glycerol and fatty acids. When used in respiration, glycerol is converted to an intermediate in the glycolysis pathway. Fatty acids are changed into acetyl coenzyme A Glucose Glycerol Diagram illustrates where glycerol and fatty acids enter the respiratory pathway and need not be memorised intermediate Fat Pyruvate Fatty acids Acetyl coenzyme A Citric acid cycle