Date: January 4, 2016 Aim #38: How do our cells carry out aerobic cellular respiration? Do Now: Warm-Up Notebook Date Title of Activity Page # 1/4 Concept: Photosynthesis & Respiration 70 HW: 1) Cornell Notes Chapter 9-1 (Chemical Pathways) pages 221225 2) Quest- Respiration (60 point test)- next Tuesday (period 5), Wednesday (period 1&7) 3) Plant Packet (follow calendar of suggested deadlines!!) Date: January 5, 2016 Aim #38: How do our cells carry out aerobic cellular respiration? Do Now: Warm-Up Notebook Date Title of Activity 1/5 Overview of Respiration Page # 71 HW: 1) Cornell Notes Chapter 9-1 (Chemical Pathways) pages 221225 due Wednesday 2) Quest- Respiration (60 point test)- next Tuesday (period 5), Wednesday (period 1&7) 3) Plant Packet (follow calendar of suggested deadlines!!) Crash Course ATP & Cellular Respiration https://www.youtube.com/watch?v=00jbG_cfGuQ Aim #38: How do our cells carry out aerobic cellular respiration? 1) What is the formula for cellular respiration? C6H12O6 + 6O2 6CO2 + 6H2O + 38ATP 2) Let’s not forget the Big Picture: ATP P P + + Energy + ADP + Energy Cell Respiration Cell Activities 3) Cell Respiration Involves OxidationReduction Reactions This involves the transfer of H+ ions and electrons from one compound to another Every time H+ and its electrons are transferred, energy is also transferred Oxidation-Reduction Reactions 4) Oxidation vs. Reduction Oxidation: Reduction: 1)A process that releases energy 1)A process that consumes energy 2)An atom loses electrons 2) An atom gains electrons 3) A substance loses H+ 4)LEO- lose electrons oxidation 3) A substance gains H+ 4) GER- gain electrons reduction NAD+ & FAD+ In cells, there are special compounds that help carry Hydrogen and their electrons from one compound to another. **The Hydrogen and electrons are both sources of energy. These structures help enzymes work, so they are known as coenzymes 5) What is NAD+ and NADH? Compounds transfer electrons and Hydrogens to NAD+ during cell respiration forming NADH. NADH will be utilized later on in cellular respiration to create more ATP molecules Cell Respiration & Burning are types of Oxidation ENERGY 1)Single reaction 2)Occurs at high temps. 3)No enzymes required 4)Aerobic- must have O2 1)Series of reactions 2)Occurs at body temp 3)Involves enzymes 4)May be aerobic or anaerobic 6) Structure of the Mitochondria 1) 2 Membranes (inner & outer) 2)Matrix- thick fluid on the inside of the inner Membrane 3) Intermembrane Space- the space between the 2 membranes. ** Many of the enzymes & other molecules are involved in respiration are built into the inner membrane. Date: January 6, 2016 Aim #38: How do our cells carry out aerobic cellular respiration? Do Now: Warm-Up Notebook Date Title of Activity 1/6 The Mitochondria 1/6 Glycolysis **2 Warm-Ups Today** Page # 72 73 HW: 1) Cornell Notes Chapter 9-2 (Krebs Cycle & ETC) pages 226-232 due Friday 2) Quest- Respiration (60 point test)- next Tuesday (period 5), Wednesday (period 1&7) 3) Plant Packet (follow calendar of suggested deadlines!!) The Steps of Aerobic Cellular Respiration 1. Glycolysis (same as anaerobic respiration) 2. Acetyl CoA Formation 3. Krebs Cycle 4. Electron Transport Chain (ETC) 7) Stage 1: Glycolysis Glucose + 2ATP + 2NAD+ 2 Pyruvate + 2NADH + 4ATP Where does Glycolysis take place? Cytoplasm Stage 1: Glycolysis Glucose + 2ATP + 2NAD+ 2 Pyruvate + 2NADH + 4ATP 3 Carbon Pyruvate 6 Carbon Structure ** Initial investment of energy to break Glucose (2 ATP) 3 Carbon Pyruvate Glycolysis Summary: 1)It takes place in the cytoplasm 2)It requires an input of 2 ATP molecules 3)It creates 4 ATP molecules (net gain of 2) 4)It creates two NADH molecules 5) The 2 pyruvates still hold most of the energy of the original glucose molecule 6) It does not require oxygen!!!!! 8) Stage 2: Acetyl CoA Formation • takes place in the Matrix of the mitochondria • Pyruvate created during glycolysis now diffuses into the mitochondrion. • It will now be converted into a twocarbon compound called Acetyl CoA • Continuing the oxidation of the organic molecule Pyruvate + CoA+ NAD+ Acetyl CoA + 2NADH + 2CO2 Stage 2: Acetyl CoA Formation 9) Stage 3: Krebs Cycle • Takes place in the matrix of mitochondria • AKA: citric acid cycle • Acetyl CoA created during step 2 now enters the Krebs Cycle • Complete oxidation of the organic molecule to carbon dioxide 2 Acetyl-CoA 4 CO2 + 6NADH + 2FADH2 + 2 ATP Summary of Krebs Cycle: 1)Takes place in the mitochondrial matrix 2) Produces 6 NADH molecules 3)Produces 2 FADH2 molecules 4) Produces 4 CO2 5) Each glucose molecule sends 2 acetyl-CoA through the cycle 6) Produces only 2 ATP molecules for each glucose 10) Stage 4: Electron Transport Chain Takes place on inner folds of mitochondria (cristae) NADH & FADH2 are electron carriers which transfer their electrons to a succession of membrane proteins on the inner membrane of the mitochondria NADH 3ATPs FADH2 2ATPs Cytochromes This process releases energy and helps form ATP molecules Stage 4: Electron Transport Chain ** Notice that the final acceptor of the electrons & Hydrogen is Oxygen. Oxygen is a very strong “electron grabber” Hydrogen ions (H+) then combine with the negative charged oxygen atoms to form water ** This process produces 34 ATP molecules 11) Oxidative Phosphorylation: • AKA chemiosmosis • Actual mechanism by which ATP is produced • It uses the energy stored in the proton gradient to power the synthesis of ATP • Depends on enzyme ATP synthetase • As protons move through the ATP synthetase channel, part of the molecule turns and attaches phosphates to ADP molecules, forming molecules of ATP. Summary of Cellular Respiration Summary of Cell Respiration: Stage Location Products Glycolysis Cytoplasm Acetyl CoA Formation Mitochondrial Matrix Mitochondrial Matrix 4 ATP (2 Net), 2 NADH, 2 pyruvate 2 NADH, 2 CO2 2 ATP, 6 NADH, 2 FADH2, 4CO2 34 ATP, H2O Krebs Cycle ETC / OP Inner Membrane Aerobic Total Energy Gain • Glycolysis: 2 ATP • Pyruvic Acid Breakdown: 0 ATP • Kreb’s Cycle: 2 ATP • Electron Transport Chain: • Total: 34 ATP 38 ATP Aerobic Cellular Respiration General Summary Energy Materials used Materials produced Time frame Location Importance Chemical bonds in glucose ATP Glucose, oxygen, water ATP, carbon dioxide, and water 24/7 Mitochondria Provides energy for life functions Amoeba Sisters Cellular Respiration & Mighty Mitochondria https://www.youtube.com/watch?v=4Eo7JtRA7lg