Warm-Up / EOC Prep 1. The triplet code of bases for RNA may be represented by all of the following except — A. CGG B. CGT C. CGU D. CGA 2. Which of these will complete the mRNA strand matched to DNA? A. AUG B. CAG C. GUC D. UAC Announcements • Today & Tomorrow- Review • Wednesday- EXAM 2 Mitosis vs. Meiosis Review Notes • The cell cycle is a series of cellular growth and division in the life of the cell. • Stages: • 1. G1-first growth, cell undergoes normal activities and grows fast • 2. S-Synthesis-DNA is copied (replicated) • 3. G2-second growth, prepare for mitosis • 4. M-Mitosis-division of the nucleus • 5. Cytokinesis-division of the cytoplasm • The cell cycle is regulated by proteins. W/o this regulation it may result in cancer, the uncontrolled growth of cells • Mitosis is a form of asexual reproduction. Mitosis includes one division that produces two cells that are identical to one another and to the parent. There is no crossing over and no variation created because the cells are identical. • Mitosis includes four phases: • 1. Prophase-chromosomes become visible and the spindle forms • 2. Metaphase-chromosomes move to the center of the cell and line up along the equator • 3. Anaphase-centromeres divide and the two chromatids move to opposite poles attached to spindle fibers • 4. Telophase-nuclear envelope forms around the chromosomes at each pole, the chromosomes uncoil, and the spindle dissolves • Meiosis is a form of sexual reproduction. Meiosis includes two divisions that produce four cells that are different from one another and to the parent. There is crossing over and variation created because the cells are different. • MEIOSIS CUTS THE CHROMOSOME NUMBER IN HALF! • Meiosis includes eight phases: • Prophase I-crossing over occurs-chromosomes become visible and the spindle forms • Metaphase I-chromosomes move to the center of the cell and line up along the equator • Anaphase I-centromeres divide and the two chomosomes move to opposite poles attached to spindle fibers • Telophase I-nuclear envelope forms around the chromosomes at each pole, the chromosomes uncoil, and the spindle dissolves • • • • Prophase II Metaphse II Anaphse II Telophase II • The spindle fibers are the hairs that pull the chromosomes apart. These spindle fibers are made by organelles called centrioles. Chromosomes (DNA wrapped in proteins) are made up of two identical sister chromatids. These chromatids are held together at the center by the centromere. • Cytokinesis, or the division of cytoplasm, follows mitosis to split the cells in half. Cytokinesis in animals occurs by pinching the cytoplasm, while cytokinesis in plants occurs by forming a cell plate between the two nuclei. This cells plate will later become the cell wall. Mitosis Meiosis Asexual or Sexual? Asexual Sexual Number of divisions 1 2 Number of cells formed 2 4 Identical or different from parent Crossing over? Identical different No Yes Genetic variation? No Yes • Combining the sperm and egg together is called fertilization. A fertilized egg is called a zygote. • Fertilization: Sperm+Egg = zygote • The gametes (reproductive cells-sperm and egg) are formed during gametogenesis. • Four sperm are produced during spermatogenesis and one egg and three polar bodies are produced during oogenesis. • Write: • Gametogenesis: forms gametes (egg/sperm) – Spermatogenesis-> 4 sperm – Oogenesis-> 1 egg + 3 polar bodies • The chromosome number must be cut in half to make the sperm and egg haploid (N) cells. All other body cells are diploid (2N) because they contain a full set of chromosomes. • Haploid (N) half the chromosome #, sex cells • Diploid (2N) full chromosome #, body cells • There are 23 pairs of chromosomes-46 in total. Each pair is made up of one chromosome from mom and one from dad. • Examples: • a frog cell starts meiosis with 30 chromosomes, how many will be in the gametes? 15 • A liver cell starts mitosis with 40 chromosomes, how many will be in each of the daughter cells? 40 Review • When does crossing over occur? • Prophase I of meiosis • In which stage of mitosis do the chromosomes line up at the equator? • Metaphase • How many cell divisions and cells are produced in meiosis? • 2 cell divisions-four cells produced • If an organisms has 40 chromosomes in their body, how many are found in the gametes? • 20 • If 10 chromosomes are found in the body cells, how many are found in the gametes? • 5 • Mit/Mei/CC Worksheet Genetics Review Questions • 10 minutes- complete them on your own first • 10 minutes- discuss with your table partner and decide on an answer • 5 minutes- which ones were hard and why? • BINGO • Clean-up • Cool-Down • Study hard tonight