ADULT ECHOCARDIOGRAPHY Lesson Seven The Mitral Valve Harry H. Holdorf PhD, MPA, RDMS, RVT, LRT, N.P. Mitral Stenosis • Etiology – Rheumatic (commissarial fusion – most common) – Congenital (rare-Parachute) – Acquired (mitral annular calcification (MAC) – Prosthetic valve dysfunction Parachute Mitral Valve (single papillary muscle) • The insertion of mitral chordae tendineae into a single papillary muscle is: – Parachute mitral valve Pathophysiology • Diffuse leaflet thickening, scarring, contraction, commissural fusion and chordae shortening and fusion • Associated mitral regurgitation may be present • Increased left atrial pressure causes LA dilatation • Long-standing obstruction leads to pulmonary hypertension (RV & RA enlargement) • Decrease in cardiac output • Acute rheumatic fever: betahemolytic strep, Polyarthritis, fever, subcutaneous nodules, carditis, and a rash (45% develop MS) • Increased risk for endocarditis Physical Signs (MS) • Diastolic murmur (rumble with opening snap • Atrial fibrillation is common • CHF symptoms (dyspnea, fatigue, orthopnea, peripheral edema • Hemoptysis (bloody sputum) • ECHO – Thickened MV leaflets with decreased mobility – Tethered MV leaflet tips (“hockey-stick” presentation) – Left atrial enlargement – Signs of pulmonary hypertension in advanced cases – Planimeter valve area in parasternal SAX view – RV and RA enlargement • NOTES: – Longstanding MS does NOT lead to: Left ventricular dilatation – MS murmur = low frequency “Diastolic rumble” with an opening SNAP!! – Know “hockey-stick” presentation (goes with rheumatic MS) – Patients with mitral stenosis often develop atrial fibrillation – Which cardiac valve is the second most common to be affected by rheumatic heart disease? Aortic • MS patients become very symptomatic with A-fib. • Might lose 50% of diastolic filling since they are very dependent on atrial contraction. • AHA/ACC Guidelines for Mitral Stenosis severity: MVA (cm sq.) – Mild >1.5 – Moderate1.0 – 1.5 – Severe <1.0 Supportive findings – Pulm. Artery pressure (mmHg) • Mild < 30 • Moderate 30 - 50 • Severe > 50 Mitral Stenosis 2D Severe doming • Doppler – Increased velocity and turbulence across the mitral valve – Use pressure half-time for valve area – Mitral regurgitation may be present – Measure mean trans-valvular gradient Mitral valve area Normal 4-5 cm sq. Mild >1.5 cm sq. Mod 1.5 – I cm sq. Sev <1 cm sq. NOTE: with atrial fibrillation, mitral stenosis velocity calculations are best performed: averaged over 5-10 beats Mitral pressure half-time • Mitral valve area: – To calculate mitral valve area: • MVA (cm sq.) = 220/pressure half time • 220 is the empirical number – Given a mitral pressure halftime of 400 msec, what would the area be? – 220/400 = .5 Mitral valve half-time… Deceleration time End of Lesson Seven NEXT: THE TRICUSPID VALVE