NURS 2410 Unit 1 Nancy Pares, RN, MSN Metro Community College Ethical decision making model • Context – Who is involved, what is the setting – What other information is needed – What personal beliefs of the nurse may impact the situation • Clarification of the issues – What are the ethical issues – Who should decide the issue • Identification of alternatives and potential outcomes Decision making cont • Ethical reasoning – What ethical theories have bearing on the situation – Should some theories be given greater weight in the decision making process – What legal or social constraints are factors – What obligations might be present in the role of the nurse Decision making model cont • Resolution – What is the best action in this situation – What strategy should be used to carry out this action • Evaluation – What were the outcomes – Should this same action be used in the future for similar dilemmas Figure 1–1 Individualized education for childbearing couples is one of the prime responsibilities of the maternal-newborn nurse. Maternal-Newborn Nursing Roles • • • • • Professional Nurse Certified Registered Nurse Nurse Practitioner Clinical Nurse Specialist Certified Nurse Midwife Figure 1–4 A certified nurse-midwife confers with her client. SOURCE: Photographer, Jenny Thomas Factors Contributing to Family Values • • • • Religion and social beliefs Presence and influence of the extended family Socialization within the ethnic group Communication patterns Factors Contributing to Family Values (cont’d) • Beliefs and understanding about health and illness • Permissible physical contact with strangers • Education Legal Issues • Standards of care: – Minimum criteria for competent, proficient, delivery of nursing care • Institutional policies • Ethical implications Legal Issues (cont’d) • Scope of practice: – Defined by state’s Nurse Practice Act – Identifies parameters within which nurses may practice • Laws Negligence • • • • There was a duty to provide care. The duty was breached. Injury occurred. The breach of duty caused the injury (proximate cause). Maternal-Child Issues • Divergence between rights of mother and rights of fetus: – Mother may refuse fetal intervention. – Fetal intervention may be forced on mother. • Fetal research: – Therapeutic vs. non-therapeutic Figure 1–5 A collaborative relationship between nurse and physician contributes to excellent client care. SOURCE: Photographer, Elena Dorfman Maternal-Child Issues • Intrauterine fetal surgery: – Therapy for anomalies incompatible with life – Health of the mother and fetus is at risk – Surrogate, frozen embryo, – Female circumcision Maternal-Child Issues • Abortion – Can be performed until point of viability – After viability, if mother’s health in jeopardy • Nursing role – Have right to refuse to assist – Responsible for ensuring a qualified replacement is available Maternal-Child Issues • • • • • Infertility Human stem cells Cord blood Maternal refusal for c/del Maternal refusal for fetal surgery Standards of Care • Womens’ health standards by Association of Women’s Health, Obstetric and Neonatal Nurses (AWHONN) • State Boards • Individual facilities policy Practicing Safety • • • • • • • A holistic interpersonal approach Adequate documentation Communication Updated and realistic policies and procedures Appropriate delegation Question deviations from the standar Follow chain of command Benefits of Evidence-Based Practice • Transforms research findings into clinical practice: – Efficiency improvement – Better outcomes – Quality improvement Cell Division • Mitosis: – Exact copies of original cell • Meiosis: – Production of new organism • Deletion Genetic terms – Loss of chromosome material • Translocation – Misplacement • Nondisjunction – Chromosomes don’t separate correctly • Karotype – Chromosomal make up of an individual Mosaicism two or more genetically different cell populations in an individual Figure 11–2 Comparison of mitosis and meiosis. Mitosis • • • • • Interphase Prophase Metaphase Anaphase Telophase Meiosis • First division: – Chromosomes replicate, pair, and exchange information. – Chromosome pairs separate, and cell divides. • Second division: – Chromatids separate and move to opposite poles. – Cells divide, forming four daughter cells. Oogenesis • • • • • Ovary gives rise to oogonial cells. Cells develop into oocytes. Meiosis begins and stops before birth. Cell division resumes at puberty. Development of Graafian follicle. Spermatogenesis • Production of sperm • First meiotic division: – Primary spermatocyte replicates and divides. • Second meiotic division: – Secondary spermatocytes replicate and divide. • Produce four spermatids. Figure 11–3 Gametogenesis involves meiosis within the ovary and testis. A, During meiosis, each oogonium produces a single haploid ovum once some cytoplasm moves into the polar bodies. B, Each spermatogonium, in contrast, produces four haploid spermatozoa. Fertilization • • • • Uniting sperm and ovum form a zygote Ova are fertile for 12 to 24 hours Sperm are fertile for 72 hours Takes place in the ampulla of fallopian tube Changes in Sperm • Capacitation: – Removal of plasma membrane and glycoprotein coat – Loss of seminal plasma proteins • Acrosomal reaction: – Release of enzymes – Allows entry through corona radiata Figure 11–4 Sperm penetration of an ovum. A, The sequential steps of oocyte penetration by a sperm are depicted moving from top to bottom. B, Scanning electron micrograph of human sperm surrounding a human oocyte (750οΎ—). The smaller spherical cells are granulosa cells of the corona radiata. SOURCE: Used with permission from Nilsson, L. (1990). A child is born. New York: Dell Publishing. After Sperm Entry • Zone pellucida blocks additional sperm from entering • Secondary oocyte completes second meiotic division – Forms nucleus of ovum • Nuclei of ovum and sperm unite • Membranes disappear • Chromosomes pair up Twins • Fraternal: two ova and two sperm • Identical: single fertilized ovum - Originate at different stages Pre-embryonic • Cleavage • Blastomeres form morula • Blastocyst: - develops into embryonic disc and amnion • Trophoblast: - develops into chorion Implantation • Occurs 7 to 10 days after fertilization • Blastocyst burrows into endometrium • Endometrium is now called decidua Embryonic Development • Primary germ layers: – Ectoderm – Mesoderm – Endoderm Placenta • Metabolic and nutrient exchange • Maternal portion: – Decidua • Fetal portion: – Chorionic villi • Fetal surface covered by amnion Placental Development • Chorionic villi form spaces in decidua basalis • Spaces fill with maternal blood. • Chorionic villi differentiate: – Syncytium: outer layer – Cytotrophoblast: inner layer • Anchoring villi form septa Figure 11–13 Longitudinal section of placental villus. Spaces formed in the maternal decidua are filled with maternal blood; chorionic villi proliferate into these maternal blood-filled spaces and differentiate into a syncytium layer and a cytotrophoblast layer. Umbilical Cord • Body stalk fuses with embryonic portion of the placenta • Provides circulatory pathway from chorionic villi to embryo: – One vein • Delivers oxygenated blood to fetus: – Two arteries Figure 11–14 Vascular arrangement of the placenta. Arrows indicate the direction of blood flow. Maternal blood flows through the uterine arteries to the intervillous spaces of the placenta and returns through the uterine veins to maternal circulation. Fetal blood flows through the umbilical arteries into the villous capillaries of the placenta and returns through the umbilical vein to the fetal circulation. Placental Functions • • • • • Nutrition Excretion Fetal respiration Production of fetal nutrients Production of hormones Fetal Development: Week 4 • • • • • • Beginning development of GI tract Heart is developing Somites develop—beginning vertebrae Heart is beating and circulating blood Eyes and nose begin to form Arm and leg buds are present Fetal Development: Week 6 • • • • • Trachea is developed Liver produces blood cells Trunk is straighter Digits develop Tail begins to recede Fetal Development: Week 12 • • • • • • Eyelids are closed Tooth buds appear Fetal heart tones can be heard Genitals are well-differentiated Urine is produced Spontaneous movement occurs Fetal Development: Week 16 • • • • • • Lanugo begins to develop Blood vessels are clearly developed Active movements are present Fetus makes sucking motions Swallows amniotic fluid Produces meconium Fetal Development: Week 20 • • • • Subcutaneous brown fat appears Quickening is felt by mother Nipples appear over mammary glands Fetal heartbeat is heard by fetoscope Fetal Development: Week 24 • Eyes are structurally complete • Vernix caseosa covers skin • Alveoli are beginning to form Fetal Development: Week 28 • Testes begin to descend • Lungs are structurally mature Fetal Development: Week 32 • Rhythmic breathing movements • Ability to partially control temperature • Bones are fully developed but soft and flexible Fetal Development: Week 36 • Increase in subcutaneous fat • Lanugo begins to disappear Fetal Development: Week 38 • Skin appears polished • Lanugo has disappeared except in upper arms and shoulders • Hair is now coarse and approximately 1 inch in length • Fetus is flexed Factors Influencing Development • • • • Quality of sperm or ovum Genetic code Adequacy of intrauterine environment Teratogens Essential Components of Fertility: Female • • • • Favorable cervical mucus Clear passage between cervix and tubes Patent tubes with normal motility Ovulation and release of ova Essential Components of Fertility: Female (cont’d) • No obstruction between ovary and tubes • Endometrial preparation • Adequate reproductive hormones Essential Components of Fertility: Male • • • • Normal semen analysis Unobstructed genital tract Normal genital tract secretions Ejaculated spermatozoa deposited at the cervix Preliminary Investigation of Infertility • • • • • Ovulation Cervix Uterine structures Tubal patency Semen analysis Figure 12–2 Sequence of events in a normal reproductive cycle showing the relationship of hormone levels to events in the ovarian and endometrial cycles. Treatment of Infertility Problems • Ovulatory: – Pharmacologic treatment – Donor oocytes • Cervical: – THI, IVF, GIFT Treatment of Infertility Problems (cont’d) • Uterine/Tubal: – IVF, GIFT – Donor oocytes or gestational carrier • Sperm: – THI, IVF, GIFT – Micromanipulation Figure 12–8 Assisted reproductive techniques. Physiologic and Psychological Effects • • • • • • Marriage may be stressed Relationship affected by intrusiveness Guilt Frustration Anger Shame Physiologic and Psychological Effects (cont’d) • Loss of control • Feelings of reduced competency and defectiveness • Loss of status and ambiguity as a couple • A sense of social stigma • Stress on the personal and sexual relationship • A strained relationship with healthcare providers Nursing Management of Infertility • Counselor • Educator • Advocate Indications for Preconceptual Genetic Testing • Maternal age 35 or over • Family history: – Known or suspected Mendelian genetic disorder – Birth defects and/or mental retardation Indications for Preconceptual Genetic Testing (cont’d) • Previous pregnancies: – Previous child with chromosomal anomaly – Previous child with metabolic disorder – Two or more first trimester spontaneous abortions Indications for Preconceptual Genetic Testing (cont’d) • Parental genetics: – Couples with a balanced translocation – Couples who are carriers for a metabolic disorder • Abnormal MSAFP • Women with teratogenic risk Autosomal Dominant Disorders • • • • • Multigenerational 50% chance of passing on the gene Males and females equally affected Varying degrees of presentation Diseases – Achondroplasia – Marfans – Neurofibromotosis • Achondroplasia – Most common dwarfism, lifespan and IQ WNL • Marfans – Connective tissue disorder, triad of ocular, skeletal and CV alterations • Neurofibromotosis (Von Recklinhausen) – Soft tumor development of peripheral nerves Figure 12–19 Autosomal dominant pedigree. One parent is affected. Statistically, 50% of offspring will be affected, regardless of sex. Autosomal Recessive Disorders • • • • Carrier parents 25% chance of passing on abnormal gene 25% chance of an affected child If child is clinically normal, 50% chance child is carrier • Males and females equally affected • Diseases: CF, Sickle Cell, PKU, Tay Sachs Figure 12–20 Autosomal recessive pedigree. Both parents are carriers. Statistically, 25% of offspring will be affected, regardless of sex. X-linked Recessive Disorders • No male-to-male transmission • 50% chance carrier mother will pass the abnormal gene to sons (affected) • 50% chance carrier mother will pass the abnormal gene to daughters (carrier) • Diseases: Hemophilia A, Duchennes MD, Trisomies, Klinefelters, Turner’s Cri du chat, Fragile X Figure 12–21 X-linked recessive pedigree. The mother is the carrier. Statistically, 50% of male offspring will be affected, and 50% of female offspring will be carriers. Genetic Testing • • • • • Genetic ultrasound Genetic amniocentesis Chorionic villus sampling Percutaneous umbilical blood sampling MSAFP Figure 12–22 A, Genetic amniocentesis for prenatal diagnosis is done at 14 to 16 weeks’ gestation. B, Chorionic villus sampling is done at 8 to 10 weeks, and the cells are karyotyped within 48 to 72 hours. Nurse’s Role • • • • Educate about tests Provide support Refer for counseling Resource during and after counseling Alcohol Use in Pregnancy • Maternal effects: – Malnutrition – Bone-marrow suppression – Increased incidence of infections – Liver disease • Neonatal effects: – Fetal alcohol spectrum disorders (FASD) Figure 19–2 Percentages of pregnant females ages 15 to 44 reporting past month alcohol use, by trimester, 2003–2004. SOURCE: Substance Abuse and Mental Health Services Administration (SAMHSA). (2005). Results from the 2004 National Survey on Drug Use and Health: National Findings. Office of Applied Studies, NSDUH Series H-28 DHHS Publication No. SMA 05-4062. Rockville, MD: Author. Cocaine Use in Pregnancy: Maternal Effects • • • • • Seizures and hallucinations Pulmonary edema Respiratory failure Cardiac problems Spontaneous first trimester abortion, abruptio placentae, intrauterine growth restriction (IUGR), preterm birth, and stillbirth Cocaine Use in Pregnancy: Fetal Effects • Decreased birth weight and head circumference • Feeding difficulties • Neonatal effects from breast milk: – Extreme irritability – Vomiting and diarrhea – Dilated pupils and apnea Heroin Use in Pregnancy • Maternal effects: – Poor nutrition and iron-deficiency anemia – Preeclampsia-eclampsia – Breech position – Abnormal placental implantation – Abruptio placentae – Preterm labor Heroin Use in Pregnancy (cont’d) • Maternal effects: – Premature rupture of the membranes (PROM) – Meconium staining – Higher incidence of STIs and HIV • Fetal effects: – IUGR – Withdrawal symptoms after birth Substance Use in Pregnancy: Maternal Effects • Marijuana: difficult to evaluate, no known teratogenic effects • PCP - maternal overdose or a psychotic response • MDMA (Ecstasy) - long-term impaired memory and learning Figure 19–1 Percentages of females ages 15 to 44 reporting past month use of any illicit drugs, by pregnancy status and age, 2003–2004. SOURCE: Substance Abuse and Mental Health Services Administration (SAMHSA). (2005). Results from the 2004 National Survey on Drug Use and Health: National Findings. Office of Applied Studies, NSDUH Series H-28 DHHS Publication No. SMA 05-4062. Rockville, MD: Author. Pathology of Diabetes Mellitus (DM) • Endocrine disorder of carbohydrate metabolism • Results from inadequate production or utilization of insulin • Cellular and extracellular dehydration • Breakdown of fats and proteins for energy Gestational Diabetes (GDM) • Carbohydrate intolerance of variable severity • Causes: – An unidentified preexistent disease – The effect of pregnancy on a compensated metabolic abnormality – A consequence of altered metabolism from changing hormonal levels Effect of Pregnancy on Carbohydrate Metabolism • Early pregnancy: – Increased insulin production and tissue sensitivity • Second half of pregnancy: – Increased peripheral resistance to insulin Maternal Risks with DM • • • • • Hydramnios Preeclampsia-eclampsia Ketoacidosis Dystocia Increased susceptibility to infections Fetal and Neonatal Risks with DM • • • • • • Perinatal mortality Congenital anomalies Macrosomia IUGR RDS Polycythemia Fetal and Neonatal Risks with DM (cont’d) • Hyperbilirubinemia • Hypocalcemia Screening for DM in Pregnancy • Assess risk at first visit: – Low risk - screen at 24 to 28 weeks – High risk - screen as early as feasible Risk Factors • Age over 40 • Family history of diabetes in a first-degree relative • Prior macrosomic, malformed, or stillborn infant • Obesity • Hypertension • Glucosuria Screening Tests • One-hour glucose tolerance test: – Level greater than 130-140 mg/dl requires further testing • 3-hour glucose tolerance test: – GDM diagnosed if 2 levels are exceeded Treatment Goals • Maintain a physiologic equilibrium of insulin availability and glucose utilization • Ensure an optimally healthy mother and newborn • Treatment: – Diet therapy and exercise – Glucose monitoring – Insulin therapy Figure 19–4 The nurse teaches the pregnant woman with gestational diabetes mellitus how to do home glucose monitoring. SOURCE: Photographer, Jenny Thomas. Fetal Assessment • • • • • AFP Fetal activity monitoring NST Biophysical profile Ultrasound Nursing Management • Assessment of glucose • Nutrition counseling • Education about the disease process and management • Education about glucose monitoring and insulin administration • Assessment of the fetus • Support Iron-deficiency Anemia • Maternal complications: – Susceptible to infection – May tire easily – Increased chance of preeclampsia and postpartal hemorrhage – Tolerates poorly even minimal blood loss during birth Iron-deficiency Anemia (cont’d) • Fetal complications: – Low birth weight – Prematurity – Stillbirth – Neonatal death Iron Deficiency Anemia (cont’d) • Prevention and treatment: – Prevention - at least 27 mg of iron daily – Treatment - 60-120 mg of iron daily Folate Deficiency • Maternal complications: – Nausea, vomiting, and anorexia • Fetal complications: – Neural tube defects • Prevention - 4 mg folic acid daily • Treatment - 1 mg folic acid daily plus iron supplements Sickle Cell Anemia • Maternal complications: – Vaso-occlusive crisis – Infections – Congestive heart failure – Renal failure Sickle Cell Anemia (cont’d) • Fetal complications include fetal death, prematurity, and IUGR. • Treatment: – Folic acid – Prompt treatment of infections – Prompt treatment of vaso-occlusive crisis Thalassemia • Treatment: – Folic acid – Transfusion – Chelation HIV in Pregnancy • Asymptomatic women - pregnancy has no effect • Symptomatic with low CD4 count - pregnancy accelerates the disease • Zidovudine (ZDV) therapy diminishes risk of transmission to fetus • Transmitted through breast milk • Half of all neonatal infections occurs during labor and birth HIV in Pregnancy: Maternal Risks • • • • Intrapartal or postpartal hemorrhage Postpartal infection Poor wound healing Infections of the genitourinary tract HIV Effects on Fetus • Infants will often have a positive antibody titer • Infected infants are usually asymptomatic but are likely to be: – Premature – Low birth weight – Small for gestational age (SGA) Treatment During Pregnancy • Counsel about implications of diagnosis on pregnancy: – Antiretroviral therapy – Fetal testing – Cesarean birth Cardiac Disorders in Pregnancy • • • • • Congenital heart disease Marfan syndrome Peripartum cardiomyopathy Eisenmenger syndrome Mitral valve prolapse Less Common Medical Conditions in Pregnancy • • • • • • Rheumatoid arthritis Epilepsy Hepatitis B Hyperthyroidism Hypothyroidism Maternal phenylketonuria Less Common Medical Conditions in Pregnancy (cont’d) • Multiple sclerosis • Systemic lupus erythematosus • Tuberculosis Chapter 20 Pregnancy at Risk: Gestational Onset Spontaneous Abortion • • • • Threatened abortion Imminent abortion Incomplete abortion Complete abortion Figure 20–1 Types of spontaneous abortion. A, Threatened. The cervix is not dilated, and the placenta is still attached to the uterine wall, but some bleeding occurs. B, Imminent. The placenta has separated from the uterine wall, the cervix has dilated, and the amount of bleeding has increased. C, Incomplete. The embryo/fetus has passed out of the uterus; however, the placenta remains. Figure 20–1 (continued) Types of spontaneous abortion. A, Threatened. The cervix is not dilated, and the placenta is still attached to the uterine wall, but some bleeding occurs. B, Imminent. The placenta has separated from the uterine wall, the cervix has dilated, and the amount of bleeding has increased. C, Incomplete. The embryo/fetus has passed out of the uterus; however, the placenta remains. Figure 20–1 (continued) Types of spontaneous abortion. A, Threatened. The cervix is not dilated, and the placenta is still attached to the uterine wall, but some bleeding occurs. B, Imminent. The placenta has separated from the uterine wall, the cervix has dilated, and the amount of bleeding has increased. C, Incomplete. The embryo/fetus has passed out of the uterus; however, the placenta remains. Spontaneous Abortion (cont’d) • Missed abortion • Recurrent pregnancy loss • Septic abortion Spontaneous Abortion: Treatment • • • • Bed rest Abstinence from coitus D&C or suction evacuation Rh immune globulin Spontaneous Abortion: Nursing Care • Assess the amount and appearance of any vaginal bleeding • Monitor the woman’s vital signs and degree of discomfort • Assess need for Rh immune globulin. • Assess fetal heart rate • Assess the responses and coping of the woman and her family Ectopic Pregnancy: Risk Factors • • • • • • Tubal damage Previous pelvic or tubal surgery Endometriosis Previous ectopic pregnancy Presence of an IUD High levels of progesterone Ectopic Pregnancy: Risk Factors (cont’d) • • • • • Congenital anomalies of the tube Use of ovulation-inducing drugs Primary infertility Smoking Advanced maternal age Ectopic Pregnancy: Treatment • Methotrexate • Surgery Figure 20–2 Various implantation sites in ectopic pregnancy. The most common site is within the fallopian tube, hence the name “tubal pregnancy.” Ectopic Pregnancy: Nursing Care • Assess the appearance and amount of vaginal bleeding • Monitors vital signs • Assess the woman’s emotional status and coping abilities • Evaluate the couple’s informational needs. • Provide post-operative care Gestational Trophoblastic Disease: Symptoms • • • • Vaginal bleeding Anemia Passing of hydropic vesicles Uterine enlargement greater than expected for gestational age • Absence of fetal heart sounds • Elevated hCG Gestational Trophoblastic Disease: Symptoms • Low levels of MSAFP • Hyperemesis gravidarum • Preeclampsia Gestational Trophoblastic Disease: Treatment • D&C • Possible hysterectomy • Careful follow-up Figure 20–3 Hydatidiform mole. A common sign is vaginal bleeding, often brownish (the characteristic “prune juice” appearance) but sometimes bright red. In this figure, some of the hydropic vessels are being passed. This occurrence is diagnostic for hydatidiform mole. Gestational Trophoblastic Disease: Nursing Care • • • • Monitor vital signs Monitor vaginal bleeding Assess abdominal pain Assess the woman’s emotional state and coping ability Bleeding Disorders • Placenta previa - placenta is improperly implanted in the lower uterine segment • Abruptio placentae - premature separation of a normally implanted placenta from the uterine wall Cervical Incompetence: Treatment • • • • • • Serial cervical ultrasound assessments Bed rest Progesterone supplementation Antibiotics Anti-inflammatory drugs Cerclage procedures Figure 20–4 A cerclage or purse-string suture is inserted in the cervix to prevent preterm cervical dilatation and pregnancy loss. After placement, the string is tightened and secured anteriorly. Hyperemesis Gravidarum: Treatment • • • • Control vomiting Correct dehydration Restore electrolyte balance Maintain adequate nutrition Hyperemesis Gravidarum: Nursing Care • Assess the amount and character of further emesis • Assess intake and output and weight. • Assess fetal heart rate • Assess maternal vital signs • Observe for evidence of jaundice or bleeding • Assess the woman’s emotional state Nursing Care of Clients with PROM • • • • • • Determine duration of PROM Assess gestational age Observe for signs and symptoms of infection Assess hydration status Assess fetal status Assess childbirth preparation and coping Nursing Clients with PROM (cont’d) • Encourage resting on left side • Provide comfort measures • Provide education Nursing Care of Clients with Preterm Labor • Identify risk for preterm labor • Assess change in risk status for preterm labor • Assess educational needs of the woman and her loved ones • Assess the woman’s responses to medical and nursing intervention • Teach about the importance of recognizing the onset of labor Signs and Symptoms of Preterm Labor • Uterine contractions occurring every 10 minutes or less • Mild menstrual like cramps felt low in the adbomen • Constant or intermittent feeling of pelvic pressure • Rupture of membranes • Low, dull backache, which may be constant or intermittent Signs and Symptoms of Preterm Labor (cont’d) • A change in vaginal discharge • Abdominal cramping with or without diarrhea Classification of Hypertension in Pregnancy • Preeclampsia-eclampsia • Chronic hypertension • Chronic hypertension with superimposed preeclampsia • Gestational hypertension Characteristics of Preeclampsia • • • • • Maternal vasospasm Decreased perfusion to virtually all organs Decrease in plasma volume Activation of the coagulation cascade Alterations in glomerular capillary endothelium • Edema Characteristics of Preeclampsia (cont’d) • • • • Increased viscosity of the blood Hyperreflexia Headache Subcapsular hematoma of the liver Figure 20–7 A, In a normal pregnancy, the passive quality of the spiral arteries permits increased blood flow to the placenta. B, In preeclampsia, vasoconstriction of the myometrial segment of the spiral arteries occurs. Figure 20–7 (continued) A, In a normal pregnancy, the passive quality of the spiral arteries permits increased blood flow to the placenta. B, In preeclampsia, vasoconstriction of the myometrial segment of the spiral arteries occurs. Hypertensive Effects on Fetus • • • • Small for gestational age Fetal hypoxia Death related to abruption Prematurity Home Management • Monitoring for signs and symptoms of worsening condition • Fetal movement counts • Frequent rest in the left lateral position • Monitoring of blood pressure, weight, and urine protein daily • NST • Laboratory testing Management of Severe Preeclampsia • • • • • • Bed rest High-protein, moderate-sodium diet Treatment with magnesium sulfate Corticosteroids Fluid and electrolyte replacement Antihypertensive therapy Signs and Symptoms of Eclampsia • • • • • • Scotomata Blurred vision Epigastric pain Vomiting Persistent or severe headache Neurologic hyperactivity Signs and Symptoms of Eclampsia (cont’d) • Pulmonary edema • Cyanosis Management of Eclampsia • • • • • • Assess characteristics of seizure Assess status of the fetus Assess for signs of placental abruption Maintain airway and oxygenation Position on side to avoid aspiration Suction to keep the airway clear Management of Eclampsia (cont’d) • To prevent injury, raise padded side rails • Administer magnesium sulfate Rh Incompatibility • • • • • Rh – mother, Rh + fetus Maternal IgG antibodies produced Hemolysis of fetal red blood cells Rapid production of erythroblasts Hyperbilirubinemia Figure 20–10 Rh alloimmunization sequence. A, Rh-positive father and Rh-negative mother. B, Pregnancy with Rh-positive fetus. Some Rhpositive blood enters the mother’s blood. C, As the placenta separates, the mother is further exposed to the Rh-positive blood. D, The mother is sensitized to the Rh-positive blood; anti-Rh-positive antibodies (triangles) are formed. E, In subsequent pregnancies with an Rh-positive fetus, Rh-positive red blood cells are attacked by the anti-Rh-positive maternal antibodies, causing hemolysis of red blood cells in the fetus. Administration of Rh Immune Globulin • • • • • After birth of an Rh+ infant After spontaneous or induced abortion After ectopic pregnancy After invasive procedures during pregnancy After maternal trauma ABO Incompatibility • Mom is type O • Infant is type A or B • Maternal serum antibodies are present in serum • Hemolysis of fetal red blood cells Surgery During Pregnancy • Incidence of spontaneous abortion is increased in first trimester • Insert nasogastric tube prior to surgery • Insert indwelling catheter • Encourage patient to use support stockings • Assess fetal heart tones • Position to maximize utero-placental circulation Trauma During Pregnancy • Greater volume of blood loss before signs of shock • More susceptible to hypoxemia with apnea • Increased risk of thrombosis • DIC • Traumatic separation of placenta • Premature labor Battering During Pregnancy • • • • • • Psychological distress Loss of pregnancy Preterm labor Low-birth-weight infants Fetal death Increased risk of STIs Perinatal Infections • • • • • • Toxoplasmosis Rubella Cytomegalovirus Herpes simplex virus Group B streptococcus Human B-19 parvovirus Fetal Risks: Toxoplasmosis • • • • • Retinochoroiditis Convulsions Coma Microcephaly Hydrocephalus Fetal Risks: Rubella • Congenital cataracts • Sensorineural deafness • Congenital heart defects Fetal Risks: Chlamydia • • • • • • Neurologic complications Anemia Hyperbilirubinemia Thrombocytopenia Hepatosplenomegaly SGA Fetal Risks: Herpes • Preterm labor • Intrauterine growth restriction • Neonatal infection Fetal Risks: GBS • • • • • Respiratory distress or pneumonia Apnea Shock Meningitis Long-term neurologic complications Fetal Risks: Human B-19 Parvovirus • Spontaneous abortion • Fetal hydrops • Stillbirth Resources • HELLP Syndrome Society This website offers information on HELLP syndrome and patient support. It also promotes research to assist prevention and treatment of this disease. • Preeclampsia The Preeclampsia Foundation is a nonprofit organization dedicated to funding research, raising public awareness, and providing support and education to patients diagnosed with preeclampsia. Resources • Group B Streptococcal Infection The CDC offers guidelines for providing care to the patient with group B strep and professional resources. • Bleeding Disorders in Pregnancy OBGYN.net provides an ultrasound image collection of bleeding disorders in pregnancy. Resources • Herpes in Pregnancy Herpes.com provides information about how herpes affects pregnancy. • Gestational Trophoblastic Disease The American Cancer Society provides information about gestational trophoblastic disease including symptoms, detection, and treatment. Resources • Hyperemesis Education and Research Organization This site provides a wealth of information and support to patients suffering with hyperemesis gravidarum and healthcare professional information as well. The site is well researched and offers information written by medical professionals. • Preterm Labor Sidelines.org is a site provided to support those experiencing a high-risk pregnancy. Nurse’s Role in Pain Relief • Support decision for pharmaceutical pain relief • Offer alternative therapies if pharmaceuticals not desired • Support changes in decision • Educate about options • Reassure that accepting medication for pain is not failure Systemic Analgesia Common indications for medications Systemic Analgesia • Goal is to provide maximum pain relief with minimal risk • Alteration in maternal state affects fetus Administration of Systemic Analgesia • • • • • When woman is uncomfortable Well-established labor pattern Contractions occurring regularly Significant duration of contractions Moderate to strong intensity Maternal Assessments • • • • The woman is willing to receive medication Vital signs are stable Contraindications are not present Knowledge of other medications being administered Fetal Assessments • • • • Fetal heart rate between 110 and 160 bpm Reactive nonstress test Short-term variability is present Long-term variability is average Assessment of Labor Progress • • • • Contraction pattern Cervical dilatation Fetal presenting part Station of the fetal presenting part Nursing Considerations • Record the drug name, dose, route, site on EFM strip and chart • Record the woman’s blood pressure and pulse (before and after) on the EFM strip and chart • Safety precautions – Raising the side rails – Assessment of the FHR Sedatives • Use: early latent phase • Purpose: relaxation and sleep • Common medications - Seconal and Ambien H1-receptor antagonists • Use - Early latent phase • Purpose - Sedative, antiemetic • Common medications - Phenergan, Vistaril, Bendadryl Narcotics • Use: active phase • Purpose - pain management • Common medications - Stadol, Nubain, Demerol • Narcotic antagonist - Narcan Regional Anesthesia • Temporary and reversible loss of sensation • Prevents initiation and transmission of nerve impulses • Types – Epidural – Spinal – Combined epidural-spinal Epidural: Advantages • Produces good analgesia • Woman is fully awake during labor and birth • Continuous technique allows different blocking for each stage of labor • Dose of anesthetic agent can be adjusted Epidural: Disadvantages • • • • • • Maternal hypotension Postdural puncture seizures Meningitis Cardiorespiratory arrest Vertigo Onset of analgesia may not occur for up to 30 minutes Spinal Block: Advantages • • • • Immediate onset of anesthesia Relative ease of administration Smaller drug volume Maternal compartmentalization of the drug Spinal Block: Disadvantages • High incidence of hypotension • Greater potential for fetal hypoxia • Uterine tone is maintained, making intrauterine manipulation difficult • Short acting Combined Spinal-Epidural: Advantages • Spinal agent has a faster onset • Medication can be added to increase the effectiveness • Preserves motor functioning • Most drugs are used in low dose Combined Spinal-Epidural: Disadvantages • Higher incidence of nausea and pruritus Pudendal • Perineal anesthesia for the second stage of labor, birth, and episiotomy repair • Advantages are ease of administration and absence of maternal hypotension • Urge to bear down may be decreased Figure 25–7 A, Pudendal block by the transvaginal approach. B, Area of perineum affected by pudendal block. Figure 25–7 (continued) A, Pudendal block by the transvaginal approach. B, Area of perineum affected by pudendal block. Local • Used for episiotomy repair • Advantage is that it involves the least amount of anesthetic agent • The major disadvantage is that large amounts of solution must be used Nursing Management: Prior to Administration • • • • Assess maternal and fetal status Assess labor progress Start an IV and administer preload Help woman into position Nursing Management: After Administration • • • • • • Monitor maternal and fetal vital signs Assess for hypotension Tale corrective measures for hypotension Administer antiemetics as needed Monitor respiratory rate Assess bladder and catheterize if unable to void Complications of Epidural Anesthesia • Toxic reactions – Unintentional placement of the drug – Excessive amount of the drug – Accidental intravascular injection • Spinal headaches Complications of Spinal Anesthesia • • • • • • Hypotension Drug reaction Total spinal neurologic sequelae Spinal headache Nausea, shivering, and urinary retention Ineffective anesthesia Complications of Pudendal Anesthesia • • • • Systemic toxic reaction Broad ligament hematoma Perforation of the rectum Trauma to the sciatic nerve Methods of General Anesthesia • Intravenous injection – Sodium thiopental (Pentothal) – Ketamine • Inhalation of anesthetic agents – Nitrous Oxide – Low-dose halogenated agents Complications of General Anesthesia • Fetal depression – Depth and duration • Uterine relaxation • Potential for chemical pneumonitis – Decrease in gastrointestinal motility – Acidic gastric secretions Contraindications • Preterm infant – Avoid analgesia during labor • Preeclampsia – Regional anesthesia is preferred – General anesthesia may aggravate hypertension Contraindications (continued) • Diabetes – Potential for decreased uteroplacental flow due to hypotension – Increased risk of cardiovascular depression with regional • Cardiac – Continuous epidural avoids cardiovascular changes with bearing down Contraindications (continued) • Bleeding – Regional blocks are contraindication due to reduction in volume