Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System Learning Outcomes Upon completing this chapter, you will be able to: 15-1 Specify the components of the afferent and efferent divisions of the nervous system, and explain what is meant by the somatic nervous system. 15-2 Explain why receptors respond to specific stimuli, and how the organization of a receptor affects its sensitivity. Identify sensory information relayed by general and special senses. Describe how stimuli are detected and interpreted. 15-3 Identify the receptors for the general senses, and describe their location and how they function. Given a scenario describe what receptors would be used to monitor stimuli and how the body would respond. Describe location of receptors and classify as tonic or phasic. Be able to answer questions similar to clinical scenario application questions. Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System I. Nervous System Organization Nervous System Peripheral Nervous System (PNS) Central Nervous System (CNS) Brain + Spinal Cord Afferent division Efferent division (to bring to) (to bring out) Somatic Nervous System (SNS) Sympathetic Division II. Autonomic Nervous System (ANS) Parasympathetic Division Sensory Receptors A. Detect info about external/internal environment B. 3 classifications of sensory receptors: 1. Interoceptors: monitor internal environment 2. Exteroceptors: monitor external environment 3. Proprioceptors: monitor position of muscles/joints C. Stimulus translated to AP CNS = transduction D. If no transduction = no awareness of stimuli E. Receptors, sensory neurons and sensory pathways make up afferent division of PNS Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System III. 15-1 Sensory Information A. General Senses 1. receptors found throughout body 2. simple structure 3. information relayed to primary sensory cortex 4. receptors are sensitive to: a. Temperature b. Pain c. Touch d. Pressure e. Vibration f. Proprioception B. Special Senses 1. Receptors are more complex 2. Information distributed to specific areas of cerebral cortex 3. Provide information about a. Olfaction (smell) b. Vision (sight) c. Gustation (taste) d. Equilibrium (balance) e. Hearing IV. The Detection of Stimuli A. Receptor specificity: 1. receptors sensitive to specific stimuli 2. Examples: a. Touch receptors sensitive to pressure, not chemical stimuli b. Taste receptors sensitive to chemicals, not pressure stimuli B. Sensation: arriving information from receptors via AP C. Perception: conscious awareness of sensation D. Receptive field: 1. area monitored by single receptor 2. the larger the field the harder to localize stimulus 3. body = larger fields 4. tongue/fingertips = very small receptive fields E. Simple receptors 1. dendrites of sensory neurons 2. Branching tips of dendrites = free nerve endings 3. Not protected by accessory structures 4. Little specificity (i.e.: free nerve endings respond to stimulus caused by chemicals, pressure, temperature or trauma) F. Complex receptors 1. Found in sense organs 2. Example: eye’s visual receptors 3. Protected by accessory cells and CT 4. Specific (i.e.: receptors cells in eye are protected by accessory structures and CT, usually only stimulus reaches these cells is light) Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System V. Interpretation of Sensory Information A. Sensory neurons relay info from receptor to specific cortex areas (i.e. primary sensory cortex receives information about touch, pressure, pain and temperature) B. Link between receptor and cortical neuron = labeled line C. Axons of labeled line carry info about one type of stimulus (modality) D. CNS interprets modality based on labeled line 1. Cannot tell difference between true/false sensation 2. i.e.: rub eyes = mechanical stimulus causes visual of flashes of lights; any activity along optic nerve travels to visual cortex = visual perception E. Frequency/pattern of AP determines strength, duration and variation of stimulus F. Sensory coding = translation of complex sensory info into meaningful patterns of AP VI. Receptor Type A. Tonic 1. 2. 3. B. Phasic 1. 2. 3. Always active A.k.a slow-adapting receptors: little change in receptor activity over time Indicates background level of stimulation Normally inactive Provide info about intensity and rate of change of stimulus A.k.a. fast-adapting receptors: respond strongly at first, activity declines Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System VII. General Sensory Receptors A. Classified into four types based on stimulus that excites them Receptor General Information Location(s) Function(s) Mechanoreceptors Stimulus caused by Tactile Receptors Tactile Receptors distortion of plasma Free nerve endings: Free nerve endings: tonic, small membranes; three between epidermal cells receptive fields; sensitive to classes: tactile touch/pressure receptors, baroreceptors, Root hair plexus: w/ hair Root hair plexus: phasic, proprioceptors follicles respond rapidly; detect initial contact and subsequent movement Merkel cells and tactile discs: stratum basale Merkel cells and tactile discs: tonic, small receptive field, extremely sensitive; sense fine touch and pressure Tactile corpuscle: eyelids, lips, fingertips, nipples, external genitalia Tactile corpuscle: phasic, fine touch/pressure Lamellated corpuscle: dermis Lamellated corpuscle: phasic; deep pressure Ruffini corpuscle: deep dermis Baroreceptors: free nerve endings in elastic tissue; respond immediately, adapt rapidly Ruffini corpuscle: tonic; pressure Baroreceptors: monitor pressure changes in organs (i.e. monitor BP in walls of major vessels or degree of lung expansion) Proprioceptors: 3 major groups Muscle spindles: found in skeletal muscles Proprioceptors: Muscle spindles: monitor length of skeletal muscle and trigger stretch reflexes Golgi tendon organs: located at junction between skeletal muscle and its tendon Golgi tendon organs: monitor external tension developed during muscle contraction Receptors in joint capsules Receptors in joint capsules: detect pressure, tension and movement at the joint Chapter 15: Neural Integration I – Sensory Pathways and the Somatic Nervous System Receptor Nociceptors General Information Location(s) Tonic Superficial portions of skin Joint capsules Periosteum Walls of BVs Thermoreceptors Phasic; more cold receptors than warm receptors; carried along same pathway as pain sensations Chemoreceptors Only respond to water or lipid soluble substances dissolved in body fluids (i.e. interstitial fluid, CSF, plasma); information sent to brain stem, not cortex Free nerve endings in dermis, skeletal muscles, liver and hypothalamus Information sent to thalamus, reticular formation of midbrain, primary sensory cortex Carotid and aortic bodies Function(s) Detects pain Myelinated Type A fibers detect fast or prickling pain (i.e. injection or deep cut) Type C fibers detect slow or burning/aching pain Detect information about temperature Monitor pH, CO2 and O2 levels