Name of the module/subject Faculty Major Specialization Level of studies Syllabus Part A - Description of the subject Molecular Biology, Group of detailed education results Genetics Group code B, C Group name Dentistry Dentistry uniform MA studies* X BA studies MA studies PhD studies Post-graduate studies full-time X part-time X I Semester of studies: obligatory X elective major-oriented basic X Polish English X other Form of studies Year of studies Type of class Kind of class Language of instruction *choose accordingly by marking with X Form of instruction Lecture Seminar Tutorial Major-oriented class (non-clinical) Clinical class Laboratory class Specialization class (MA) Simulated conditions class Lectorate Practical classes with a patient Physical education exercises Apprenticeship Self-study Other I Hours 10 5 25 - Total 40 Education aims: 1. Students should learn the basics of contemporary genetics and experimental methods used in genetics. 2. Students gain information about the influence of environment pollution by mutagenic and carcinogenic substances on the human organism. 3. Students learn the fundaments of medical parasitology, the structure and life cycles of human parasites and learn how to recognize the symptoms of parasitic infection. The methods of verifying the intended education results and the form of class in the context of the matrix of education results for module/subject: Methods of verifying Student who completes the whether the intended Type of class No. of the module/subject will know/be education results have education result able to: been achieved (forming ** enter symbol and summarizing) written test and exam L, S W 01 define the basic terms used in genetics written test and exam L, S W 02 list the genetic factors determining the human traits written test and exam L, S W 03 explain the basic processes involved in gene expression and its regulation written test and exam L, S W 04 explain the impact of environment pollution by mutagenic and carcinogenic factors on human organism and to describe the phenotype effects of mutagenesis, chosen genetic diseases and mechanisms of their inheritance written test MC W 05 describes the biology and morphology of human parasites (Protozoa, Platyhelminthes and Nemathelminthes) MC W 06 describes the epidemiology and written test prophylactics of parasitic infections written test MC W 07 describes the basic methods used in diagnosis of parasitic infections written test U 01 recognizes the relations between environment pollution and human pathology written test U 02 uses the methods of genetics and molecular biology in disease diagnosis U 03 analyses the genetic crosses and written test pedigree trees practical test U 04 uses the optic microscope written test U 05 recognizes the form and stages of parasites that are invasive for U 06 K 01 K 02 K 03 humans recognizes the basic symptoms of parasitic infections and uses the prophylactic methods actively participates in didactic process cooperates to solve the given problems actively searches information sources and critically analyses them written test ** L - lecture; S - seminar; T - tutorial; MC - major-oriented classes (non-clinical); CC - clinical classes; LC - laboratory classes; SC – specialization classes (MA); SC - simulated conditions classes; LE - lectorate; P - practical classes with a patient; PE - physical education classes (obligatory); A - apprenticeship; SS - self-study Please mark with pluses (scale 1-3) how the abovementioned effects place your module/subject in the sections: passing on knowledge, skills or forming behaviors, e.g.: Knowledge +++ Skills ++ Behaviors + Student's work input (ECTS points): Type of student's work Student's workload (h) (participating in class, activity, preparation, tests etc.) 40 1. Hours on-site 15 2. Own work 55 Summary of the student's workload 6 ECTS points per module/subject Remarks Subject of class: (enter the topic of each class, including the division for the type of class; remember the topic of class has to translate into intended education results) Lectures 1. Structure of genetic material (DNA, RNA), double helix structure. Replication, transcription and translation in Prokaryota and Eukaryota. 2. Gene expression and its regulation. 3. Human genome organization, mitochondrial genome. 4. DNA variability, mutations, mechanisms of DNA repair. Mutagenic factors, influence of drugs, chemical compounds, physical factors and environmental pollution. 5. Basic methods of molecular biology and their applications Seminars 1. Protein biosynthesis, operons. 2. Mechanisms of gene mutations, chromosomal structural and numerical aberrations. 3. Chosen autosomal and X-linked genetic diseases. Classes 1. Protozoa of gastrointestinal and genitourinary systems. 2. Tissue protozoa. 3. Flukes and tapeworms of gastrointestinal and respiratory systems. 4. Gastrointestinal nematoda. 5. Tissue helmints. 6. Mendelian genetics, meiosis, gametogenesis. 7. Gene cooperation, cytoplasmic inheritance. 8. Morgan theory of chromosomal inheritance. 9. Sex determination, Lyon hypothesis. Other Basic sources: (list according to significance, no more than 3 items) 1. 2. 3. A. Cisowska, D. Tichaczek-Goska, M. Wesołowska, D. Wojnicz ”Medical biology for students faculty of medicine and faculty of dentistry” University of Medicine in Wrocław 2009 W.S. Klug, Cummings M.R. “Genetics: a molecular perspective” Prentice Hall 2003 B.J. Bogitsch, T.C. Cheng „Human parasitology“ Second edition, Academic Press 1998 Additional sources and other resources: (no more than 3 items) 1. Connor M., Ferguson-Smith M. “Essential medical genetics” Blackwell Science Ltd 1997 2. R. Muller “Worms and human disease” Second edition, CABI Publishing 2002 Requirements for teaching resources: (e.g. laboratory, projector, other...) Classroom equipped with microscopes and multimedia Entry requirements: (the minimum conditions the student has to meet prior to entering the module/class) Knowledge of basic terms in genetics and ecology Conditions for completing the course: (what are the terms and conditions of obtaining credits from particular classes within the module/subject, the terms and conditions of being allowed to take the final exam, the terms and conditions for passing the final exam, the requirements for particular grades) Passing partial tests in genetics and parasitology, passing the final exam (test form). Grade: Very good (5.0) Good plus (4.5) Good (4.0) Sufficiently good (3.5) Sufficient (3.0) Grading criteria: (only for subjects/modules ending with an exam) 91-100% 82-90% 73-81% 64-72% 55-63%