Body tissues are divided into 4 categories: 1. Connective 2. Nerve 3. Muscle 4. Epithelial -Functions: Connect, support, transportation (blood), defense, and storage (fat) -cells are surrounded by some type of non-living matrix -classified by their structure and the type of matrix -there are four major classes of connective tissue with subcategories I. Fibrous, II. Bone, III. Cartilage, IV. Blood a) Loose- the stretchable fascia between organslike an elastic glue spread between organs b) Adipose- fat storage under the skin -important for protection and insulation c) reticular- web like fibers of the lymphatic (immune) system - helps filter blood - contains white blood cells to destroy dangerous invaders d) dense- tendons and ligaments –flexible but strong -tendon- connects muscle to bone -ligament- connects bone to bone bone cells are called osteocytes -osteoblast- bone building cell -osteoclast- bone destroying cell the 2 cells above work together and can reshape bone a “unit” of bone is known as the Haversian System (see fig 5-20) the cells are squeezed between the hard matrix of mineral salts (mostly calcium) flat bones are called membranous bones (skull, pelvis) Osteocytes Cross-section of long bone chondrocytes are cartilage producing cells cartilage is avascular (no blood vessels) there are 3 subcategories of cartilage a) hyaline cartilage- shiny and smooth, at the ends of bones (linings of joints) chondrocytes b) Fibrocartilage- strongest and most durable, “shock absorbers” (intervertebral discs, meniscus of the knee joint) c) Elastic cartilage- most flexible cartilage (ears, nose, larynx) Considered a connective tissue because it is made in the bones Hematopoiesis- the process of blood production in the has a liquid matrix called plasma red marrow of the bones There are 3 main types of blood cells: 1) Erythrocytes- red blood cells: carry O2 (some CO2) 2) Leukocytes- white cells: kill invaders 3) Thrombocytes- responsible for blood clotting by producing platelets All are responsible for movement -May be voluntary or involuntary -May be striated or non-striated Voluntary= may be “willed” to move Involuntary= not controlled by thought or will Striated= visible “stripes” on tissue Non-striated= no visible “stripes Striated and voluntary Cells are very long and thin with multiple nuclei Non-striated and involuntary Cells are shorter and each with one nucleus Striated and involuntary Cells connect at dark “disks” and only one nucleus per cell. -Rapidly regulate and integrate body activities -2 basic kinds of cells 1. neurons=conducting cells 2. glial cells= support cells Soma: main body of cell (nucleus is here) Dendrites: short thin branches that carry signal towards the soma Axon: long thin “wire” carrying signal away from the soma Synapse: where neurons connect to transmit signal Schwann Cells- wrap around the axon to insulate the “wiring” to speed nerve signal transmision - Responsible for the fatty white matter of the nervous system -Cells are tightly packed into sheets with no “matrix” between cells -sheets of cells attached to a “basement membrane” -cells are attached to each other by “tight junction” making a tight seal - one side is “exposed” to either internal or external environment -2 main types: membranous glandular Classification is based on shapes and layers: Description of Cell Shapes: Squamous -(flat and scaly) Cuboidal -(cubic) Columnar -(tall narrow column) Pseudostratified columnar -(odd columns, not all reach the surface) Description of Layers: Simple (one layer) Stratified (several layer of same cell type) Transitional (many layers transitioning to different cell types) Simple Squamous - VERY thin. Where quick diffusion is necessary lining of blood vessels, tiny air sacs in lungs, parts of kidney, etc. “flat” Cross-section Stratified Squamous - areas that receive friction skin, mouth, esophagus Cross-section Cuboidal - lines many ducts and tubules Cross-section Columnar epithelium - may be ciliated with tiny “hairs” (cilia) Non ciliated - lines gastrointestinal tract Ciliated - lines respiratory tract Transitional - bladder – allows for expansion Cross-section Synthesizes and secretes a chemical product oEndocrine gland- secrete directly to bloodstream oExocrine gland- secrete into collecting ducts oUnicellular gland- single cells called goblet cells that produce mucous Pituitary: Example of an endocrine gland Exocrine glands come in a wide variety of shapes: Exocrine Secretion: Merocrine- hormones released through cell membrane (sweat & salivary glands, mucous producing goblet cells) Apocrine- part of cell containing hormones pinches off (mammary gland) Holocrine- cell bursts to secrete products and must be replaced (sebaceous gland)