"Everyone is an athlete. The only difference is that some of us are in training, and some are not." Dr. George Sheehan Optimize exercise performance Prevent hypoglycemia during and after any physical activity Rapidly manage hypoglycemia caused by or following exercise Prevent hyperglycemia and DKA Assess patients for conditions that might contraindicate certain types of exercise such as: Uncontrolled hypertension Severe autonomic neuropathy or peripheral neuropathy History of foot lesions Unstable proliferative retinopathy Patient’s age and previous physical activity level should be considered Encourage patient to start with short periods of lowintensity exercise and slowly increase intensity and duration Advise people with diabetes to perform: At least 150 min/week of moderate- intensity aerobic physical activity ▪ 50–70% of maximum heart rate ▪ Spread over at least 3 days per week with ▪ No more than 2 consecutive days without exercise DIABETES CARE, VOLUME 35, SUPPLEMENT 1, JANUARY 2012, www.care.diabetesjournals.org Factors That Affect Blood Glucose Levels INSULIN Time STRESS Type EXERCISE & BLOOD GLUCOSE Amount ALCOHOL/drugs BLOOD GLUCOSE Time Type Amount FOOD Time EXERCISE ILLNESS Farquar, A July 17, 2008 DESA International Toronto, Canada Type Amount Weightlifting, Power lifting Track (sprinting/field events), Diving (Platform & springboard) American football, Swimming (sprints), Gymnastics, Fencing Wrestling, Volleyball, Ice hockey, Track cycling Basketball, Soccer, Tennis, Lacrosse Speed skating (500-1000m) Skiing (slalom & downhill), Field hockey Rowing (middle distance) Running (middle distance), Speed skating (>1500m) Road cycling In-line skating Cross country skiing Race walking Marathon running Iron Man triathlon Ultra-marathon running Hyperglycemia ANAEROBIC Short duration High-intensity AEROBIC Longer duration Lower Intensity Hypoglycemia Absorption Rate The rate at which subcutaneously injected insulin is absorbed increases with exercise due to increases in body temperature and in subcutaneous and skeletal muscle blood flow Exogenously administered insulin levels do not decrease during exercise Zinman B, Murray FT, Vranic M, et al. Glucoregulation during moderate exercise in insulin treated diabetics. J Clin Endocrinol Metab. 1977;45:641–652. Humalog, Novolog, Apidra (4–6 hours) Regular (6–10 hours) Plasma Insulin Levels NPH (12–20 hours) Detemir (Up to 24 hours) Glargine (20–26 hours) 0 2 4 6 8 10 12 14 16 18 Hours Adapted from American Diabetes Association. Diabetes in the Latino Population. Diabetes Core Curriculum Workshop Available at: http://www.diabetes.org/uedocuments/LatinoSlidesAugust05.ppt. 20 22 24 Hypoglycemia Risk Weekend warriors or untrained person Increased duration, intensity and/or frequency New activity Hypoglycemia unawareness Recent physical activity or hypoglycemia within last 24 hours Alcohol use *Alcohol will stop liver from releasing glycogen Duration Adjustment Notes 2 hrs per drink -50% Begin after drinking Frequently, strenuous exercise causes an increase in insulin sensitivity as well as the restoration in muscle glycogen storage May need insulin level adjustment to avoid frequent carbohydrate correction More frequent glucose monitoring Frequent monitoring Consume extra carbohydrates when necessary Keep accurate records of duration, intensity, and frequency Reduce insulin that is active at time of exercise Check BG often during exercise and in the following 24 to 36 hours (look for patterns) Begin Temp rate before exercise begins May need to lower boluses before exer. ~50% less as a starting point May need lower bolus to correct high BG before or during longer periods of exer. Disconnect can be an option up to one hour Or 0% Temp rate Smart Pumping, Howard Wolpert, MD Exercise 2 to 3 hours after eating Know your individual glucose response to exercise (determined from pre/post BG checks) Check you glucose levels before you exercise (30 minutes apart – Why?) Decrease the insulin dose that is working while you are exercising (consult healthcare team first) Pt. may need extra food or basal insulin adjustments up to 24hrs after exercising depending on the length/intensity of the exercise Hyperglycemia ◦ Counter regulatory hormones are released: cortisol, glucagon, growth hormone, adrenalin ◦ Glucose can increase during exercise Delay exercise if ketotic Diabetes Core Curriculum Workshop GLUCOSE LEVEL » COMMENT » Fasting* blood glucose level is 250 mg/dL (13.9 mmol/L)** Test urine and/or blood for ketones - If ketones present, exercise is contraindicated** Blood glucose value is 300 mg/dl (16.7 mmol/L) and without ketones** Exercise with caution, and continue to monitor blood glucose levels** *Fasting is defined as 4 h or more after eating a meal. **Zinman B, Ruderman N, Campaigne BN, Devlin JT, Schneider SH. Physical activity/exercise and diabetes. Diabetes Care. 2004 Allows greater flexibility Decide whether it is The Pump Club Insulin Pump best to disconnect or not May program the pump to accommodate exercise (temporary basal or separate basal program) Diabetes Core Curriculum Workshop Exercise - decrease Start Temp Basal ~ 1 ½ to 3+ hours prior to exercise End Temp Basal ~ 30 minutes to as much as 24hrs after exercise Less Activity - increase Long meetings All day seminars Long car rides The Pump Club Insulin Pump Prevention of Delayed-Onset Hypoglycemia Duration Adjustment Notes 6-10 hours -50% Base timing on experience Prolonged Activity Duration Adjustment Notes Minimum 2 hrs. -50% Start 1-2 hours prior Pumping Insulin, Walsh J, Roberts R Decreased risk of stacking insulin Less chance of hypoglycemia Decreased risk of intentionally running high due to fear of hypoglycemia May improve A1c Alternatives to Disconnection: Physical Activities Wear It! (Sport Pack, Bum Bag, Backpack Harness) Re-Connect hourly & bolus 50% of missed basal rate 6 - 20% effort 7 - 30% effort - Very, very light (Rest) Very light < 10 8 - 40% effort 9 - 50% effort - Very light - gentle walking 10 - 55% effort 11 - 60% effort - Fairly light Moderate 12-13 12 - 65% effort 13 - 70% effort - Somewhat hard - steady pace 14 - 75% effort 15 - 80% effort - Hard 16 - 85% effort Hard 14-16 17 - 90% effort - Very hard 18 - 95% effort 19 - 100% effort - Very, very hard 20 - Exhaustion Heart Rate 70-89% Borg, G, "Perceived Exertion as an indicator of somatic stress", Scandinavian journal of Rehabilitation Medicine 1970, 2(2), 92-98 Muscle glycogen contains 300-400 grams of glycogen ▪ 1200-1600 calories Liver glycogen contains 75-100 grams of glycogen ▪ 300-400 calories Blood glucose contains 25 grams of glucose ▪ 100 calories Normally takes 24 to 36 hours to replace muscle energy (glycogen) Consuming carbohydrates immediately post exercise (w/n 15 minutes) can reload the muscles in 12 to 16 hours Snack should be mostly carbohydrates and some protein (4 parts CHO’s and 1 part Pro) Added protein does not help with glycogen reloading but may repair and help with protein synthesis after exercise Nutrition shake, smoothie, peanut butter sandwich, energy bar, yogurt, turkey sandwich, string cheese and crackers Clark N, et al., “Sports Nutrition”, 124-28, 2003. •In place of more common sports drinks •When pitted against commercial sports recovery drinks, several new studies have found that chocolate milk is the superior beverage when it comes to postexercise recovery and fluid replacement •Chocolate milk is 90 percent water, so it’s ideal for rehydration •It has the perfect combination of carbohydrates and protein to refuel a tired athlete’s body, and it’s packed with many other nutrients including calcium and vitamins A and D (4 grams of carbs to 1 gram of protein) Applied Physiology, Nutrition, and Metabolism, Sept 2010 One size doesn’t fit all Variability intraindividual ▪ ~10 - 20% Variability interindividual ▪ ~20 - 35% Heinemann L, Weyer C, Rauhaus M, Heinrichs S, Heise et all, ”Variability of the Metabolic Effect of Soluble Insulin and the Rapid-Acting Insulin analog Insulin Aspart”, 2003. 197 mg/dl - start 170 117 – ate 15 grams of carbs 81 Minutes 20 30 40 188 at 7am 15 grams of carbs/protein 50% decrease in basal 8hrs cavorite-lis n -fGET tg/stores/d communit rate-item cust-rec just-say-no true m/justsay That means from the bottom of my heart but only deeper