Caffeine
Nikola Zemánek
SOURCES
Caffeine = natural substance (63 types of plants)
MOST COMMONLY :
COFFE BEANS
TEA LEAVES
COCOA – COCOA NUTS
HISTORY
Tea in China – tousands years ago
15th century – pharmacological effect
16th century – coffeehauses in Mecca
17th century – first coffeehauses in Europe
1820 – first isolation (from coffee)
FRIEDRICH FERDINAND RUNGE
CHEMISTRY VIEW
CHEMICAL NAME : 3,7–dihydro–1,3,7–trimethyl–1H-purine-2,6-dione
ALTERNATE NAMES : 1,3,7-trimethylxanthine, coffeine, thein, guaranine,
methyltheobromine, mateine
Alkaloid of the methylxanthyne family
Pure state – crystalline white powder
Biochemistry view – How does the caffeine work ?
chemical changes in the brain :
1) blocking adenosine receptors
2) dopamine effect
1) BLOCKING ADENOSINE RECEPTORS
2) INCREASING LEVEL OF DOPAMINE
STIMULATION
NERVE CELLS
RELEASE
THE HORMONE
ADRENALINE
+ GLUCOSE
POSITIVE EFFECT :
IMPROVEMENT THE MOOD + AGILITY
NEGATIVE EFFECT : INCREASED HEART RATE AND RESPIRATION...
ANOTHER VIEW - ARTISTIC
USE
STIMULATING
EFFECT
SOFT DRINKS
CocaCola, coffee, energy drinks
caffeine PILLS (students – night without sleep, possibility of overdose !!! )
caffeine benzoate – for treating headache
CONTENT OF CAFFEINE
Molecule of caffeine is very popular....
SOURCES OF INFORMATION
• http://chemistry.about.com/
• http://en.wikipedia.org/
• http://www.answers.com/
THANK YOU