Syllabus Intro to Human Physiology Lab – PHSO V01 33090 Instructor: Katherine Gould Spring 2016 Lecture Class Hours: MW 8:00-9:15 Room: ASC-130 Lab Class Hours: M or W 9:30-12:20 (Sci 316); T 1:00-3:50: Room Sci-318 Email: kgould@vcccd.edu Text: Human Physiology by Stuart Ira Fox Laboratory Experiments for Human Physiology by T. Pardee Desire2Learn PhysioEx Book/CD This course presents a survey of the functional relationships between major organ systems, tissues and cells within the human body. A heavy emphasis on the biochemistry of major physiological mechanisms will lead to an understanding of the interactions between tissues that contribute to overall homeostasis in the human body. Laboratory exercises emphasize the development of both laboratory skills pertinent to physiology as well as an understanding of the nature and significance of a variety of physiological parameters which will be measured in the lab (including ECG, respiratory measurements, electromyogram, pH and buffers, enzyme activity, and others). ANSI 287.1 safety glasses and gloves are required. Course Objectives: Upon successful completion of this course, the student will be able to demonstrate the following measurable skills and abilities: A. Demonstrate proficiency in the use of the Biopac computer system and various other laboratory instruments to collect, record and analyze physiological data. B. Research and evaluate contemporary scientific/medical literature and use that information to prepare and present an oral seminar on pathophysiology. C. Analyze the properties of important biological molecules and their relationship to important anatomical and cellular structures and physiological processes (including enzymes, buffers, acids/bases, lipids, proteins, carbohydrates, vitamins, minerals and water). D. Appraise the nature and significance of basic homeostatic mechanisms, including both positive and negative feedback mechanisms. E. Inventory the important biochemical mechanisms performed by cells of the human body which contribute to homeostatic balance (including cellular energetics, immune mechanisms, membrane functions, receptor/ligand interactions and signal transduction, etc.) F. Assess the functions of the major organ systems of the human body and the physiological and chemical mechanisms by which they work. G. Apply the principles of the scientific method to solve problems encountered in the laboratory, including the formulation and testing of hypotheses and evaluation of data obtained from properly controlled physiological experiments. Student Learning Outcomes: Students will demonstrate an understanding of neuron function, including the details of conduction and transmission. Students will demonstrate an understanding of the details of cellular respiration, including glycolysis, oxidative decarboxylation, Krebs' cycle, and electron transport, and their contribution to the production of ATP and cellular energetics. Students will demonstrate an understanding of the cardiac cycle as well as the electrical conduction system that regulates it, and will describe the relationship between the components of the electrocardiogram, the electrical activity of the heart, and the mechanical events of the cardiac cycle. Date Tentative Laboratory Topic (expect deviations from this schedule) 1/12 1/19 Homework 1/26 2/2 Homework 2/9 2/16 Introduction; Skills for Laboratory pH and Buffers PhysioEx #10 pH and Buffers (begin Glucose and Protein Lab) Spectrophotometric Determination of Glucose & Protein PhysioEx #1: Cellular Transport Measurement of Enzyme Activity Exam #1; Notebooks Due Unit 1 Notebook Score: 2/23 Homework 3/1 3/8 Reflexes; Begin Sensory Phenomena PhysioEx #3: Neurophysiology of Nerve Impulses Sensory Phenomena Lab (contd) Exam #2; Notebooks Due Unit 2 Notebook Score: 3/15 3/22 Homework 3/29 Homework Lecture 4/45 Muscle Physiology (Biopac) Spring Break PhysioEx #2: Skeletal Muscle Physiology Electrocardiogram (Biopac) PhysioEx #5 and #6: Cardiovascular Dynamics and Cardiovascular Physiology Poiseuelle’s Law: Cardiovascular System of the Frog Exam #3; Notebooks Due Unit 3 Notebook Score: 4/12 4/19 Homework 4/26 5/23 5/10 5/12 Digestion of Food Respiratory Measurements (Biopac) PhysioEx #9: Renal System Physiology Oral Pathophysiology Presentations Oral Pathophysiology Presentations Exam #4; Notebooks Due Unit 4 Notebook Score: Begin Final Exams: No final in Lab… Questions on Lecture Final! Laboratory Packets: Four packets of laboratory information will be available for the four units of study. The professor will supply these packets, one before each unit. You are required to read, highlight in yellow, and study the appropriate sections (as indicated in the class syllabus) prior to arriving in class for the day’s exercise. You should bring your unit packets and your notebooks to each laboratory session for recording data. These laboratory packets (lab guides) are the basis of the laboratory investigations you will be performing. Notebooks: You should maintain a notebook with all of your laboratory packets, assignments and other materials from the lab. This notebook is for your study convenience and must be submitted on the day of each laboratory exam (10 points per notebook; notebooks will count for 20% of the final laboratory grade. Notebooks will be graded on completeness (you should give comprehensive answers to all study questions) as well as neatness and presentation. Only the lab syllabus (must be the first page), starred (*) pages from the packets, and other pages as instructed should be turned in with the notebook. Quizzes and Exams: There may be weekly quizzes (10 points per quiz; quizzes will count for 5% of the final lab grade). Quizzes will be given at the beginning of class (do not be late) and will cover material on the previous week’s work. Exams will be given as per the schedule on the syllabus above. The format of these laboratory exams includes essay, short answer, analysis, and/or calculation questions. There will be no laboratory make-up exams unless extenuating circumstances apply (judged on an individual basis by the professor). You must therefore be in attendance on the day of each exam during your appropriate lab period (do not attend a different lab section without prior permission). A make-up exam or the average percentage you receive on your weekly quizzes may replace one missing exam if extenuating circumstances exist and dictate such need. Exams and oral presentation will count for 75% of your final lab grade. Laboratory exam questions will be posted on D2L for your observation and study. PhysioEx Assignments: PhysioEx labs are simulated laboratory experiences that will be performed at home on your computer. These exercises are an integral component of the laboratory curriculum, and provide important information and present concepts critical to a complete understanding of human physiology. I recommend that you get together in study groups and perform the labs together, collaborating on the questions and learning important physiology together, although you may choose to do these on your own. Each PhysioEx lab should take about 2-3 hours to complete, although the learning of important concepts may take additional study time. You are responsible for reading introductory/informational material, performing the simulated lab measurements, completing all questions in spaces provided, including the Review Sheet at the end of each exercise. In your notebooks you will submit the Review Sheet for each exercise performed during that unit of study, as well as any related questions provided in the notebook itself. Laboratory exams will include questions taken from the PhysioEx exercises. Grading Scale: The grading scale will be: 90-100% = A, 75-89% = B, 60-74% = C, 5059% = D, 0-49% = F. Your grade in the lab will be averaged (on a 75%lecture/25%lab basis) with your lecture grade and one grade will be assigned for the class. Students are encouraged to attend all study sessions to augment the lecture as well as laboratory activities; in addition, you are encouraged to access the website for study guides and lecture notes as appropriate. Oral Presentation: You will be required to develop and present a PowerPoint presentation on some topic related to pathophysiology as per the schedule on the syllabus. Details for this presentation are found on page one of the first lab packet. As indicated, the lab exams and PowerPoint slide presentation will collectively count for 75% of your lab grade. Class Guidelines: Follow all guidelines found on D2L. All unit packet questions should be answered in the spaces provided; however, any “numbered” work which is done where no such spaces are provided must be titled, numbers must be circled in ink and highlighted with yellow only, and there must be a single blank space between each item. All submitted work must be accompanied with the following honor statement on the bottom of the first page of the assignment or on the colored card cover of each unit packet: “I have completed this assignment with character” in ink and must be signed. In addition, all assignments must have the initials of your lab section in red ink letters in the upper left corner of the page (ex: Tam for students in Tuesday morning lab). The honor statement is part of the exam grade and is worth -5 points on 100 point assignments and -1 point on ten point assignments if not done correctly. Ditto for the lab section designation. This syllabus is a tentative guideline and may be modified in an equitable manner as deemed appropriate by the instructor to meet the needs of this unique class. You are responsible for following all the guidelines under "Class Guidelines" on the Desire2Learn site (ask for a copy if you do not have internet access). If you have a disability that may require classroom or test accommodations, please see me as soon as possible so that your learning needs may be appropriately met. If you have not already done so you will also need to contact the Educational Assistance Center at 654-6300 to receive authorization for your accommodations. Their office is located in the Administration Building, just across from the Student Services Center.