MODULE SPECIFICATION TEMPLATE
MODULE DETAILS
Module title
Module code
Credit value
Level
Mark the box to the right of the
appropriate level with an ‘X’
Advanced Chemistry I
CH311
10
Level 4
Level 5
Level 6
Level 0 (for modules at foundation level)
X
Level 7
Level 8
Entry criteria for registration on this module
Pre-requisites
CH211, CH213
Specify in terms of module codes or
equivalent
Co-requisite modules
Specify in terms of module codes or
equivalent
Module delivery
Mode of delivery
Taught
Other
X
Distance
Placement
Pattern of delivery
Weekly
X
Block
Other
When module is delivered
Semester 1
Other
X
Semester 2
Online
Throughout year
Brief description of module The module provides a balanced programme of study in Chemistry
content and/ or aims
at Level 6 and complements other more specialised final year
Overview (max 80 words)
Module team/ author/
coordinator(s)
School
Site/ campus where
delivered
chemistry modules.
Dr G Gallacher, Dr S Mikhalovsky, Dr P Cragg
School of Pharmacy and Biomolecular Sciences
Moulsecoomb
Course(s) for which module is appropriate and status on that course
Course
Status (mandatory/ compulsory/
optional)
Pharmaceutical and chemical sciences
Analytical Chemistry with Business
Chemistry
MChem
compulsory
compulsory
compulsory
compulsory
MODULE AIMS, ASSESSMENT AND SUPPORT
Aims
To provide a balanced programme of study in Chemistry at Level
6 and to complement specialist final year modules
Learning outcomes
At the end of this module students should be able to:
Module descriptor template: updated Aug 2014
1 solve problems in modern physical chemistry;
2 apply fundamental physical chemistry to technological and
biomedical problems;
3 offer explanations, based on molecular conformations and
energetics, for observed regioselectivity, chemoselectivity,
stereospecificity and stereoselectivity in chemical reactions
4 design syntheses of simple organic molecules;
5 deduce the structures of molecules from spectroscopic data;
6 apply the principles of molecular recognition and
supramolecular chemistry to solve problems concerning
analyte detection by molecular sensors, artificial analogues of
complex biomolecules, and the use of supramolecular
therapeutics in nanomedicine
7
carry out relatively complex chemistry experiments in the
laboratory
Content
1. Physical Chemistry
A selection will be made from the following topics:
1.1 Electrochemistry
Models of interfacial electron transfer, the Butler-Volmer
equation, corrosion
1.2
Transport processes in chemistry.
Laminar and turbulent flow. Reynolds’ number. Fick’s first
and second laws. Stokes’ Law. Diffusion-limited kinetics.
Onsager’s generalisation of the transport equations.
1.3
Heterogenous Equilibria.
Module descriptor template: updated Aug 2014
Liquid-liquid, liquid-solid and solid-solid equilibria. Phase maps. The
Gibbs Phase Rule. One-component and two-component
systems.
1.4
Physical chemistry of membranes
Ion exchange membranes, Donnan equilibrium, biological
membranes, models of membrane transport, membrane
electrochemistry
2. Organic Chemistry
A selection will be made from the following topics:
2.1
Frontier molecular orbital theory
Diels-Alder reactions, pericyclic ring closures
2.2 C-C bond-forming reactions
Aldol condensations, Michael addition, enamine, silyl enol ethers,
Wittig, organometallic reactions
2.3
Functional group interconversions
oxidation, reduction, substitution, addition, reductive amination
2.4
Selectivity in organic reactions.
Chemoselectivity, regioselectivity stereoselectivity, stereospecificity,
enantioselectivity, diastereoselectivity.
3. Inorganic Chemistry - Supramolecular chemistry
Molecular vs. supramolecular chemistry; history and core
concepts; synthesis of key molecules and
supramolecular assemblies
Applications of supramolecular chemistry
Module descriptor template: updated Aug 2014
Biomimicry: self-assembly and self-replication; enzyme mimics;
synthetic transmembrane ion channels; capsules and
artificial cells
Diagnostics: optical and fluorescent biosensors; detection of
critical analytes; MRI agents; macrocyclic complexes for
imaging and radiotherapy
Therapeutics: phthalocyanine photodynamic therapy;
texaphyrins; supramolecular antibiotics; nanomedicine
An illustrative practical will be undertaken e.g. crown ether
assisted liquid clathrate formation; synthesis of a cryptand,
methyl[4]resorcinarene, heptylpyrogallol[4]arene or cyclic
tetralactam
Learning support
Module handbook
Lecture notes (Powerpoint)
Latest editions of:
Moore, W.J. Physical Chemistry, Wiley.
Bockris, J.O’M and Khan, S.U.M. Surface Electrochemistry,
Plenum.
Vollhardt, K.P.C.and Schore, N.E. Organic Chemistry, Freeman.
March, J. Advanced Organic Chemistry, Wiley
Shriver, D.F., Atkins, P.W. and C.H. Langford, Inorganic
Chemistry, Oxford University Press.
Powell, P. Principles of Organometallic Chemistry, Chapman &
Hall.
Supramolecular chemistry, Peter J Cragg, In the Kirk-Othmer
Encyclopedia of Chemical Technology, John Wiley &
Sons, Inc., New York
A Practical Guide to Supramolecular Chemistry Peter J Cragg,
John Wiley & Sons, Ltd., Chichester (copies in the
library)
Supramolecular Chemistry Jonathan W Steed and Jerry L
Atwood John, Wiley & Sons, Ltd., Chichester (copies in
Module descriptor template: updated Aug 2014
the library)
Supramolecular chemistry: from biological inspiration to
biomedical applications Peter J Cragg, Springer UK, London
Teaching and learning activities
Details of teaching and
learning activities
The aims of this module will be achieved through lectures (27 h),
laboratory classes (9 h), problem classes (3 h) and guided study
(61 h).
Allocation of study hours (indicative)
Study hours
Where 10 credits = 100 learning hours
SCHEDULED
This is an indication of the number of hours students can expect to
spend in scheduled teaching activities including lectures, seminars,
tutorials, project supervision, demonstrations, practical classes and
workshops, supervised time in workshops/ studios, fieldwork, and
external visits.
39
GUIDED INDEPENDENT
STUDY
All students are expected to undertake guided independent study
which includes wider reading/ practice, follow-up work, the
completion of assessment tasks, and revisions.
61
PLACEMENT
The placement is a specific type of learning away from the University.
It includes work-based learning and study that occurs overseas.
TOTAL STUDY HOURS
100
Assessment tasks
Details of assessment on
this module
End of module examination (60%) (LOs 1-6) and continuous
assessment of laboratory reports (40%) (LOs 1-7)
Types of assessment task1
% weighting
Indicative list of summative assessment tasks which lead to the award of credit or which are required for
progression.
(or indicate if
component is
pass/fail)
WRITTEN
Written exam
COURSEWORK
Written assignment/ essay, report, dissertation, portfolio, project
output, set exercise
PRACTICAL
Oral assessment and presentation, practical skills assessment, set
exercise
60
40
EXAMINATION INFORMATION
Area examination board
Chemistry and Pharmaceutical Sciences
Refer to University for guidance in completing the following sections
External examiners
Name
Position and institution
Date appointed
Date tenure
ends
1 Set exercises, which assess the application of knowledge or analytical, problem-solving or evaluative skills, are included
under the type of assessment most appropriate to the particular task.
Module descriptor template: updated Aug 2014
Professor D Shallcross
Dr G Hix
QUALITY ASSURANCE
Date of first approval
1994
Only complete where this is not the
first version
Date of last revision
2010
Only complete where this is not the
first version
Date of approval for this
version
2012 (KIS corrected Feb 16)
Version number
8
Modules replaced
CH301
Specify codes of modules for which
this is a replacement
Available as free-standing module?
Module descriptor template: updated Aug 2014
Yes
No