December 2002
SHOSHANA (MALIS) ARAD
CURRICULUM VITAE
PERSONAL DETAILS
Place of Birth:
Marital Status:
Work address
Tel:
Fax:
E-mail:
Home address :
Tel-Aviv, Israel
Married, one child
P.O. Box 653, Beer-Sheva 84105
972-8-6461963
972-8-6472983
arad@bgumail.bgu.ac.il
23a Eshel Street, Omer, 08-6469132
EDUCATION
1970
B.Sc., The Hebrew University of Jerusalem, Department of Biology
Major subjects: Microbiology and Biochemistry
1973
M.Sc. (cum laude), Ben-Gurion University, Department of Biology and
The Hebrew University of Jerusalem
Advisor: Prof. A. Richmond
M.Sc. Thesis: Cellular water content as a modulator of ribonuclease activity
1978
M.Sc., Brooklyn College of the City University of New York
1979
Ph.D., Brooklyn College of the City University of New York, Department of Biology.
Advisor: Prof. R. McGowan
Ph.D. Thesis: pH-induced aggregation in Chlorella
EMPLOYMENT HISTORY
1997-Present
Director, Institute for Applied Biosciences
1995
Full Professor, Ben-Gurion University of the Negev
1994
Incumbent, Ungar Chair of Biotechnology
1992
Head, Center of Biotechnology, Ben-Gurion University
1989
Head of team for the establishment of a Center for Biotechnology
1988
Associate Professor, The Institutes for Applied Research, Ben-Gurion University
1984
Research Grade A
1983-86
Coordinator of project: "Development of outdoor raceway capable of
yielding oil-rich halotolerant microalgae," Solar Energy Research Institute,
Department of Energy (DOE), USA
1982
Research Grade B
1981- present
1981
Senior Investigator, The Institutes for Applied Research, Ben-Gurion University
Research Grade C
1979-81
Senior Investigator, post-harvest physiology, Volcani Center and
The Institutes for Applied Research, Ben-Gurion University
1979-81
Coordinator of the Algae Project - National Council for Research and Development,
entitled: "Combined systems for algal wastewater treatment and for algal reclamation
and protein production"
1974-76
Research Fellow, Division of Natural Products, Research & Development Authority,
Ben-Gurion University in the project: "Testing the economic feasibility of large-scale
algae production in brackish water"
1973
Internship with the G.S.F. Abt. fur Algen Forschung und Algentechnologie, Dortmund,
West Germany in: "Algae growth techniques on a large scale and under laboratory
conditions"
Teaching Experience
Microbiology, Teaching Assistant in the Department of Biology, Ben-Gurion University of the Negev,
Beer-Sheva
Biology I (general biology) - lecturing and laboratory; Botany - lecturing and laboratory Teaching
Assistant in the Department of Biology, Brooklyn College of the City University of New York
Algal Physiology and Biochemistry, Teaching in the Department of Biology, Ben-Gurion University of
the Negev
"Biotechnology curriculum" Consultant in the Department of Biology, Ben-Gurion University
Head, Committee for Biotechnological Curriculum at Ben-Gurion University of the Negev
Marine Biotechnology – Department of Biotechnology Engineering, Ben-Gurion University of the Negev
CONFERENCE COMMITTEES
1980 -
Organizing Committee for the International Conference on "Control Mechanisms in
Photosynthesis," Acre, Israel, 31 August-4 September
1981
Organizer of a Symposium Summing up the Algae Project, Jerusalem, 15 March
National Council for Research & Development
1984
Organizing Committee of an International Conference on "Saline Water for Agriculture
and Aquaculture (The Third International Workshop on Biosaline Research)," BeerSheva, March
1987
Organizing Committee of Binational Conference Israel-USA on "Polysaccharides from
microalgae: A new agriculture," North Carolina, October
1989-1990
Committee International Symposium Biotechnology in Agriculture, Tiberias (August)
1990
Organizing Committee, Israel-Spain Workshop on Biotechnology.
1990
Organizing Committee, Israel-U.S. Symposium on Photosynthesis and Energy-Related
Biosciences
1992
Committee of the Annual Meeting of the Israel Society of Microbiology, Beer-Sheva
(10-11 February)
2000 -
Organizing Committee, 2000 - The Era of Biotechnology, Beer-Sheva, October
2001 -
Organizing Committee, 2001 – Bi-Institutional symposium in Glycobiology, BeerSheva (15 October)
Organizing Committee, 2002 - Bi-National France-Israel Symposium on Enabling
Nano- and Micro-Technologies in Biotechnology (31 October)
Organizing committee – The Israeli Biological Societies - Ilanit
2002 2003-
ADMINISTRATION
1985-1987
Member, Selection Committee for postdoctoral fellowships - BARD - (Binational
Agriculture Research & Development)
1989
Member, Teaching Committee of the Biotechnology program
1989-1990
Member, Committee for the Selection of the President of Ben-Gurion University, 1991
2
1993-94
Member, Committee for Selection of Rector of Ben-Gurion University
1994
Member, U.S.-Israel Science and Technology Commission
1995
Member, National Council for Research & Development
1996
Head, Institute for Applied BioSciences, Ben-Gurion University
1997-1998
Member, Council for Higher Education
1998-2001
Member, National Committee for Biotechnology
2001
Member, Committee for selection of Rector of Ben-Gurion University
1998-2004
Member, Committee of Planning and Budgeting of the Council for Higher Education
2003-
Member, National Committee for Biotechnology
2003-
Member, Committee for selection of Israel prize in Biological Research
SPECIAL INVITATIONS
•
Lecture, "Growth of algae as a new crop" presented at the National Symposium of Teachers of
Agriculture, Volcani Center, March 1980
•
Invited to present a lecture at the Eighth International Cell Cycle Conference, North Carolina, 15-16
May 1980 (unable to attend)
•
Invited lecture at the 35th annual AIBS meeting at Colorado State University, Fort Collins Symposium on Recent Advances in Microalgal Biotechnology on "Production of sulfated
polysaccharides from Porphyridium", August 1984
•
Invited to present a lecture at the XII Seaweed Symposium-Brazil, on "Production of polysaccharides
from red unicellular algae", 1986 (unable to attend)
•
Invited plenary lecture at the "Congress on Recent Progress in Algal Biotechnology", Lille, France,
September 1987
•
Invited lecture at Aquaculture International Congress, Vancouver, on "Production of biochemicals
from red microalgae", September 1988
•
Invited to give a course on Algal Biotechnology, Department of Biology, University of Bologna,
Bologna, Italy, April 1989
•
Invited lecture at Israel-Spain Workshop on Biotechnology: "Outdoor cultivation of red microalgae
for production of valuable biochemicals", Jerusalem, May 1990
•
Invited lecture at the Annual Meeting of Israel Society of Microbiology: "Red microalgae as a source
of valuable biochemicals", February 1990
•
Invited lecture at the Binational Symposium Israel, U.S. on Photosynthesis and Energy-related
Biosciences: "Outdoor cultivation of red microalgae", Jerusalem, June 1990
•
Invited lecture at the French-Israeli Meeting on Biotechnology for Food, "Production of Valuable
Biochemicals from Red Microalgae", Annecy, May 1990
•
Invited lecture at the Conference on "Advances in Applied Biotechnology ", Israel-U.S., Department
of the Army: "Outdoor cultivation of microalgae in closed system for production of valuable
biochemicals", Haifa, June 1990
•
Invited lecture at the National Research Council at Networking Meeting on Algal Biotechnology and
Production, Singapore, September 24-26, 1992
•
Invited lecture in the Japanese-Israeli Symposium on Aquaculture (JFSA) Haifa- Eilat, November 89, 1992
•
Invited lecture in the Algal Biotechnology, 6th International conference on Applied Algology, Czech
Republic, "Production of cell wall polysaccharides from red microalgae," September, 1993
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•
Invited lecture at the second National Symposium on Marine Biotechnology, Eilat: "Sulfated
polysaccharides from red microalgae: Towards production," January 1994
•
Invited to chair session on Polysaccharide from algae: Conference on Algal Biotechnology,
Montecatini, Italy, 1999
•
Invited to give the plenary lecture in Marine Biotechnology Conference, Haifa, November 2001
•
Invited to give the plenary lecture in the Israeli Oceanographic and Limnologic Society, March, 2002
•
1st Congress of the International Society for Applied Phycology 9 th International Conference on
Applied Algology, Spain, May 2002
• Invited Lecture at Public Discourse on Agri-Biotech and Genetically Modified Food in Israel, The
Heschel Center, 2003
SCIENTIFIC PUBLICATIONS
Chapters in books: 24
Articles in scientific reviewed Journals: 85
Reports: over 100
Presentation of papers: over 100
STUDENTS
MSc: 36
PhD: 14
Postdoctoral: 8
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RECENT PUBLICATIONS (from 1993)
Chapters in Books
Yaron, A. and Arad (Malis), S. Natural pigments from red microalgae for food and cosmetics. In: G.
Charalambous, Ed., Food Flavors, Ingredients and Composition. Elsevier Science Publishers B.V.
(1993), pp. 835-839.
Yaron, A., Dvir, I., Maislos, M., Mokady, S. and Arad (Malis), S. The red microalga Rhodella reticulata
as a source of a dietary -3 highly unsaturated fatty acid eicosapentaenoic acid. In: G. Charalambous,
Ed., Food Flavors: Generation, Analysis and Process Influence. Elsevier Science B.V. (1995), pp. 665674.
Arad, S. and Spharim, I. Production of valuable products from microalgae: An emerging agroindustry.
In: A. Altman, Ed., Agricultural Biotechnology. Marcel Dekker, Inc., New York (1998), pp. 629-643.
Arad (Malis), S. Polysaccharides from red microalgae, In: Z. Cohen, Ed., Chemicals from Microalgae.
Taylor & Francis, London (1999), pp. 282-29.
Arad (Malis), S. Biotechnology for production of sulfated polysaccharides from red microalgae. In: V.
Cre, R. Rizzo and G. SkjŒk-Braek, Eds., COST 49 Technology and Biotechnology of Algal
Polysaccharides: Future Trends. European Commission, EUR 18951 (1999), pp. 127-142.
Arad (Malis), S. and Richmond, A. Industrial Production of Microalgal Cell-mass and Secondary
Products-Emerging Species of High Potential (in press).
Articles in Scientific Reviewed Journals (from 1998)
Merchuk, J.C., Ronen, M., Giris, S. and Arad (Malis), S. Light/dark cycles in the growth of the red
microalga Porphyridium sp. Biotechnol. Bioengin. 59(6): 705-713 (1998).
Cohen (Katz), A. and Arad (Malis), S. Biosynthesis of the cell-wall polysaccharide in the red microalga
Rhodella reticulata. Isr. J. Plant Sci. 46(2): 144-153 (1998).
Rise, M., Prengler, M. and Arad (Malis), S. Characterization of a nicotine resistant mutant of Chlorella
emersonii. J. Plant Physiol. 152(4-5): 583-585 (1998).
Sivan, A. and Arad (Malis), S. Intraspecific transfer of herbicide resistance in the red microalga
Porphyridium sp. (Rhodophyceae) via protoplast fusion. J. Phycol. 34(4): 706-711 (1998).
Harpaz, S., Rise, M., Arad (Malis), S. and Gur, N. The effect of three carotenoid sources on growth and
pigmentation of juvenile freshwater crayfish Cherax quadricarinatus. Aquaculture Nutrition 4(3): 201208 (1998).
Eteshola E., Karpasas, M., Arad (Malis), S. and Gottlieb, M. Red microalga exopolysaccharides: Study
of the rheology, morphology and thermal gelation of aqueous preparations. Acta Polym. 49: 549-556
(1998).
Simon-Bercovitch, B., Bar-Zvi, D. and Arad (Malis), S. Cell wall formation during the cell cycle of
Porphyridium sp. (Rhodophyta). J. Phycol. 35(l):78-83 (1999).
Lapidot, M., Raveh, D., Sivan, A., Arad (Malis), S. and Shapira, M. Molecular analysis of the AHAS
gene of Porphyridium sp. (Rhodophyta) and of a mutant resistant to sulfometuron methyl. J. Phycol.
35:1233-1236 (1999).
Ucko, M., Shrestha, R.P., Mesika, P., Bar-Zvi, D. and Arad (Malis), S. Glycoprotein moiety in the cell
wall of the red microalga Porphyridium sp. (Rhodophyta) as the biorecognition site for the
Crypthecodinium cohnii-like dinoflagellate. J. Phycol. 35:1276-1281 (1999).
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Li, S-Y., Shabtai, Y. and Arad (Malis), S. Production and composition of the sulphated cell-wall
polysaccharide of Porphyridium sp. (Rhodophyta) as affected by CO2 concentration. Phycologia
39(4):332-336 (2000).
Singh, S., Arad (Malis), S. and Richmond, A. Extracellular polysaccharide production in outdoor mass
cultures of Porphyridium sp. in flat plate glass reactors. J. Appl. Phycol. 12-69-275 (2000).
Ginzberg, A., Cohen, U., Sod-Moriah, U.A., Shany, S., Rosenshtrauch, A. and Arad (Malis), S. Chickens
fed with biomass of the red microalga Porphyridium sp. have reduced blood cholesterol levels and
modified fatty acid composition in egg yolk. J. Appl. Phycol. 12-325-330 (2000).
Dvir, I, Chayoth, R., Sod-Moriah, U., Shany, S., Nyska, A., Stark, A.H., Madar, Z. and Arad (Malis), S.
Soluble polysaccharides and cells of the red microalga Porphyridium sp. reduce serum cholesterol and
alter intestinal morphology in rats. Br. J. Nutri. 84: 469-476 (2000)
Geresh, S., Dawadi, R.P. and Arad (Malis) S. Chemical modifications of biopolymers: quaternization of
the extracellular polysaccharide of the red microalga Porphyridium sp. Carbohydr. Polym. 43:75-80
(2000).
Li, S-Y., Lellouche, J-P., Shabtai, Y., and Arad (Malis) S. Fixed carbon partitioning in the red microalga
Porphyridium sp. (Rhodophyceae, Rhodophyta). J. Phycology Vol. 37 (2): 289-297 (2001).
Huleihel, M. and Arad, S. Effect of Porphyridium sp. polysaccharide on malignant cell transformation by
moloney murine sarcoma virus. Anticancer Res. 21:2073-2078 (2001).
Huleihel, M., Ishanu, V., Tal, J. and Arad, S. Antiviral effect of red microalgal polysaccharides on
Herpes simplex and Varicella zoster viruses. J. Appl. Phycol. 13: 127-134 (2001).
Lapidot, M., Raveh, D., Sivan, A., and Arad (Malis), S. and Shapira, M. Stable chloroplast tranformation
of the unicellular red alga Porphyridium sp. Plant Physiol. 129: 7-12 (2002).
Li, S-Y., Shabtai, Y. and Arad (Malis) S. Floridoside as a carbon precursor for the synthesis of cell-wall
polysaccharide in the red microalga Porphyridium sp. (Rhodophyta) Journal of Phycology Vol. 38 (5):
931-938 (2002)
Huleihel, M., Ishanu, V., Tal, J. and Arad (Malis), S. Activity of Porphyridium sp. against Herpes
simplex viruses in vitro and in vivo. J. Biochem. Biophys. Methods (2002).
Matsui, S.M., Muizzudin, N., Arad, S. and Marenus, K. Sulfated polysaccharides from red microalgae
anti-inflammatory properties in vitro and in vivo. Appl. Biochem. Biotechnol 104, 1:13-22 (2003)
Shrestha, R.P., Bar-Zvi, D. and Arad (Malis), S. A non-covalently bound cell wall glycoprotein of the red
microalga Porphyridium sp. J. Phycology (in press).
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