Far Shore Ltd, ‘Realising your Organisations Potential’ Course Outline for Design of Experiments Training Introduction The term experiment is defined as the systematic procedure carried out under controlled conditions in order to discover an unknown effect, to test or establish a hypothesis, or to illustrate a known effect. When analysing a process, experiments are often used to evaluate which process inputs have a significant impact on the process output, and what the target level of those inputs should be to achieve a desired result (output). Experiments can be designed in many different ways to collect this information. Design of Experiments (DOE) is also referred to as Designed Experiments or Experimental Design - all of the terms have the same meaning. Design of Experiments can be used at the point of greatest leverage to reduce design costs by speeding up the design process, reducing late engineering design changes, and reducing product material and labour complexity. Designed Experiments are also powerful tools to achieve manufacturing cost savings by minimizing process variation and reducing rework, scrap, and the need for inspection. Design of experiments or DOE is a set of advanced analytical tools based on mathematical techniques. Using special computer software, it is possible to gain a deep understanding of the processes, including the impact of interactions among factors, and to do so in the most efficient manner with minimum numbers of experimental runs. These tools or DOE will be presented on this training course. Timescale 2 day full time course + post course follow up Who should attend? Anyone involved in: product and process development, process and product optimisation and improvement, validation and technical services, Requirements It is useful if participants have a basic understanding of statistics, including hypothesis testing and regression. Outline course content Why DOE is so important and provides such an opportunity to business. 1 DOE basics Factorial designs Reducing Experimental Trials Planning and Preparing for a Designed Experiment Response Surface Methodologies Subjects Covered Factorial Designs Steps in data analysis Residuals Assumptions for DOE analysis Identifying large effects Main effects Interpreting interaction plots Identification of significant effect Viewing effects on the response Main effects plots Interaction plots Cube plots Prediction equation Reducing experimental trials The half fraction and confounder Fractional factorials Confounding Resolution Screening designs Plackett Burman designs Planning and Preparing for a Designed Experiment Response Variables Choosing factors Setting levels for each factor Replication Randomisation Blocking Response Surface Methodology Quadratic model Designs 2 Contour plots Software Minitab will be demonstrated as part of the training. Delegates are invited to bring a laptop loaded with either Minitab 16 or Minitab 17 and they will work through several Minitab exercises throughout the course. A free 30 day trial version of Minitab 17 is available on www.minitab.co.uk. Course Tutor Nick Ustianowski is a Master Black Belt in six sigma and lean. He has more than 17 years of experience of implementing Operational Excellence within the pharmaceutical and other regulated industries. Nick is currently working within the pharmaceutical, food, high technology and health service sectors as a trainer, business coach and transformational agent. Course Manual Delegates will receive a comprehensive course manual written by the course tutor, which explains the underlying statistics, describes the principles of experimental design, explains in detail how experiments are designed and analysed, includes examples of several practical case studies, and incorporates completed versions of all the course exercises and graphs, including the output from Minitab computer software. The course manual will provide a very useful reference for participants undertaking the design and analysis of experiments when they return to their workplace. 3