Bio 40
RECESSIVE DELETERIOUS GENE CONDITIONS
Heredity Lesson 7
MOST (not all) deleterious genes are recessive traits. Heterozygous people for
the trait are carriers but are not afflicted by the condition.
Alkaptonuria
Cystic fibrosis
Duchenne’s muscular dystrophy
Hemophilia
Lesch-Nyhan syndrome
PKU
Sickle cell anemia
Tay Sachs
Adenoleukodystrophy (ALD)
Alper’s syndrome
Zellweger’s syndrome
Aarskog syndrome
DOMINANT DELETERIOUS GENE CONDITIONS
Some deleterious genes are dominant. Heterozygous people for the trait exhibit
the condition.
Brachydactyly
Congenital stationary night blindness
Fascio-scapulo-humeral muscular dystrophy
Huntington’s disease
Pseudo-achondrophastic dwarfism
NF-1 (Neurofibromatosis type 1)
Marfan syndrome
Machado-Joseph disease
Bio 40
Heredity Lesson 7
PROJECT Poster: Precious Humans
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Select one of the conditions listed to do further research with a
partner (in diads). You may choose a disorder not listed but it must fit
these criteria before you check with your teacher:
o Must be inheritable as recessive or dominant gene
o Deleterious condition (colourblindness does not fit this
criterion)
Projects with some uncertainty MAY be permitted—eg. Breast cancer runs in
families, but the recessive/dominance is not clear. The genes that pass on
are becoming known.
No two groups may do the same project. Sign up list with your
teacher.
Two classes of time: one computer day, one work day.
Include :
 Title of the disorder.
/25 mk total
Should occupy not more than 1/6 and not less than
1/8 of the poster page. (1)
 Picture(s) showing a person with the condition if possible, or a diagram
that shows some of the characteristics. (2)
 Description of the condition and life with the condition (diagnosis,
symptoms, prognosis, treatments and current research—ie known gene
and effects) (12)
 Punnett square showing how the trait arises (2)
 Probability in the population (Canada/US/Global--specify) (2)
 State if it is culturally prevalent or not. Research further to determine
location of prevalence. (3)
3 mk are included for aesthetics—no extraneous marks, very neat, eyeappealing as an informational poster, colour, legibility at 10 feet.
Photos and charts off the computer are permitted. Anecdotal stories may be printed off as
well but count only for part of the life description—cite these directly on the print out. Other
information should not be cut/paste of the internet sites—that is plagiarism. All information
is to be neat and hand printed. Printing should be legible at 10 feet.
Cite all your sources on a separate sheet of paper. Include your name and
partner’s name along with the title.
Your name and partner’s name are on the front lower right corner.
Bio 40
Heredity Lesson 7
SIGN-UP POSTER: PRECIOUS HUMANS
RECESSIVE DELETERIOUS GENE CONDITIONS
______________________Alkaptonuria
______________________Cystic fibrosis
______________________Duchenne’s muscular dystrophy
______________________Hemophilia
______________________Lesch-Nyhan syndrome
______________________PKU
______________________Sickle cell anemia
______________________Tay Sachs
______________________Adenoleukodystrophy (ALD)
______________________Alper’s syndrome
______________________Zellweger’s syndrome
______________________Aarskog syndrome
DOMINANT DELETERIOUS GENE CONDITIONS
______________________Brachydactyly
______________________Fascio-scapulo-humeral muscular dystrophy
______________________Huntington’s disease
______________________Pseudo-achondrophastic
dwarfism
______________________NF-1 (Neurofibromatosis type
1)
______________________Marfan syndrome
______________________Machado-Joseph disease