Study Guide Clinical Nutrition & disorders CORE CURRICULUM Clinical Nutrition and Disorder Aims Capable to explain the concept of human nutrition and set the comprehensive action for nutritional problems, in health and disease in the primary care settings. Learning outcomes 1. Explain the roles of macronutrients and micronutrients in health and diseases, and its food sources 2. Estimate the general nutritional and energy requirements in relation to age, sex, activity, stress, pregnancy and nursing mother. 3. Explain the general principles of well-balanced diet 4. Assess the nutritional status in health and diseases, include determining nutritional deficiency and excess 5. Determine the difference of concepts among vitamin deficiency, dependency and toxicity 6. Identify mineral deficiency and toxicity 7. Explain the nutrition concepts, specialties and burdens through the life cycle 8. Explain the nutrition concepts for obesity and weight management, dislipidaemia and hyperurecemia 9. Explain the concept of medical nutrition therapy in primary care setting 10. Explain the concept of food supplement and functional food in primary care setting 11. Diagnose and manage common problems and diseases of micronutrient defieciencies in the primary care settings. 12. Explain the basic concepts and principles of enteral and parenteral (IntraVenous) nutrition. Curriculum content 1. 2. 3. 4. 5. 6. 7. 8. 9. Role and food sources of nutrients Need of general nutritional and energy requirements in specific physiological conditions Macro and micronutrients The concept of well-balanced diet and it’s implementation Assessment of general nutritional status that has been used in community as well as in clinical setting Management of common nutritional problems : 6.1 Malnutrition (Undernutrition) 6.2 Obesity 6.3 Weight management 6.4 Infant Feeding Practice 6.5 Dislipidaemia 6.6 Hyperurecemia The principles of medical nutritional therapy (MNT) The principles of enteral and parenteral nutrition Food Supplement and Functional Food Udayana University Faculty of Medicine, DME 1 Study Guide Clinical Nutrition & disorders ~ PLANNERS TEAM ~ No Name Departement Phone 1 Dr. dr. Gde Ngr Indraguna Pinatih, M.Sc, Sp.GK Community & Preventive Medicines 08123816424 2 Dr. dr. I Wayan Suranadi, Sp.An-KIC Anesthetic & Reanimation 08123847675 3 Dr. dr. I Gst Lanang Sidiarta, Sp.A(K) Pediatrics 08123966008 4 Dr. dr. I Wayan Weta, MS, Sp.GK Community & Preventive Medicines 081337005360 5 dr. I Wayan Gede Sutadarma, M.Gizi, Sp.GK Biochemistry 082144071268 DEPT PHONE ~ LECTURERS ~ NO NAME 1 Dr. dr. I Wayan Suranadi, Sp.An-KIC (WSR) Anesthtic and Reanimation 08123847675 2 Dr. dr. Putu Pramana, Sp.An-KMN (PRM) Anesthetic and Reanimation 08122344895/03 617405330 3 Dr. dr. I Wayan Weta, MS, Sp.GK (WT) Community and Preventive Medicines 081337005360 4 Dr. dr. Gde Ngr Indraguna Pinatih, M.Sc, Sp.GK (GNIP) Community and Preventive Medicines 08123816424 5 Dr.dr. I Gst Lanang Sidiarta, SpA.(K) (IGLS) Pediatrics 08123966008 6 dr. I Wayan Gede Sutadarma, M.Gizi, Sp.GK (SUT) Biochemistry 082144071268 Udayana University Faculty of Medicine, DME 2 Study Guide Clinical Nutrition & disorders ~ FACILITATORS ~ Regular Class NO 1 2 3 4 5 6 7 8 9 10 11 12 NAME dr. I Putu Kurniyanta, Sp.An dr. Tjok. Istri Anom Saturti, Sp.PD dr. Herman Saputra, Sp.PA dr. Yuliana, M Biomed dr. I.B. Krisna Jaya Sutawan, Sp.An, M.Kes dr. Ida Ayu Sri Wijayanti, M.Biomed, Sp.S Dr.dr. I G A Sri Mahendra Dewi, Sp.PA(K) dr. Ryan Saktika Mulyana, M.Biomed, Sp.OG dr.A.A. Ayu Dwi Adelia Yasmin, M.Biomed, Sp.JP,FIHA dr. I Made Dwijaputra Ayustha, Sp.Rad dr. I Made Oka Adnyana, Sp.S (K) dr. I Gusti Agung Gd Mahendra Wijaya, Sp.Onk,. Rad GROUP A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 A12 DEPT PHONE ROOM Anasthesi 081805755222 Interna 081916253777 Pathology Anatomy Anatomy 081338981853 Anasthesi 08123836470 Neurology 081337667939 Pathology Anatomy Obgyn 081338736481 Cardiology 087861402169 Radiology 08123670195 Neurology 0817347697 Radiology 08990179750 3rd floor R.3.01 3rd floor R.3.02 3rd floor R.3.03 3rd floor R.3.04 3rd floor R.3.05 3rd floor R.3.06 3rd floor R.3.07 3rd floor R.3.08 3rd floor R.3.20 3rd floor R.3.21 3rd floor R.3.22 3rd floor R.3.23 DEPT PHONE ROOM Interna 085237068670 Anasthesi 081338568883 Microbiology 08123921590 Pathology Anatomy Radiology 08113803933 081337165566 Interna 08123985811 Andrology 08123979397 Physiology 081338505350 Public Health 0818357777 Biochemistry 081338338611 Opthalmology 08123846995 Psychiatry 08174709797 3rd floor R.3.01 3rd floor R.3.02 3rd floor R.3.03 3rd floor R.3.04 3rd floor R.3.05 3rd floor R.3.06 3rd floor R.3.07 3rd floor R.3.08 3rd floor R.3.20 3rd floor R.3.21 3rd floor R.3.22 3rd floor R.3.23 085792652363 082147087905 English Class NO 1 2 3 4 5 6 7 8 9 10 11 12 NAME dr. I Gede Ketut Sajinadiyasa, Sp.PD dr. Kadek Agus Heryana, Sp.An dr. Made Agus Hendrayana , M.Ked dr. Ni Putu Ekawati, M.Repro, Sp.PA dr. Firman Parulian Sitanggang, Sp.Rad(K)RI dr. Ketut Suardamana, Sp.PD-KAI dr. I Made Oka Negara, S.Ked Dr.dr. I Made Muliarta, M.Kes Dr.dr. Dyah Pradnyaparamita Duarsa, M.Si Prof. dr. Nyoman Agus Bagiada, Sp.Biok dr. Anak Agung Mas Putrawati Triningrat, Sp.M (K) dr. Lely Setyawati , Sp.KJ Udayana University Faculty of Medicine, DME GROUP B1 B2 B3 B4 B5 B6 B7 B8 B9 A10 A11 B12 3 Study Guide Clinical Nutrition & disorders TIME TABLE Days/date 1st day Tuesday 1 Dec 2015 2nd Day Thursday 3 Dec 2015 3rd Day Friday 4 Dec 2015 4th Day Monday 7 Dec 2015 5th Day Tuesday 8 Dec 2015 Regular Class Time English Class 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 Udayana University Faculty of Medicine, DME Learning Activity Introduction of the Theme Independent Learning SGD Break Plenary Student project Nutrition and Life Cycle Independen Learning SGD Break Plenary Student project Well Balance Diet Independen Learning SGD Break Plenary Student project Infant and Children Feeding Practice Independent Learning SGD Break Plenary Student project Obesity and Weight Management Independent Learning SGD Break Plenary Student project Place PIC Class room GNIP Discussion room Class room Discussion room WSR Class room Class room Discussion room GNIP Class room Class room IGLS Discussion room Class room Class room GNIP Discussion room Class room 4 Study Guide Clinical Nutrition & disorders 6th Day Thursday 10 Dec 2015 7th day Friday 11 Dec 2015 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 09.00-10.00 08.00-09.00 8th day Monday 14 Dec 2015 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 09.00-10.00 08.00-09.00 9th day Tuesday 15 Dec 2015 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 10th day Wednesday 16 Dec 2015 11th day Thursday 17 Dec 2015 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.30 Udayana University Faculty of Medicine, DME 09.00-10.00 12.00-13.30 Primary Protein and Energy Malnutrition Independent Learning SGD Break Plenary Student project Secondary Protein and Energy Malnutrition Independent Learning SGD Break Plenary Student project Minerals Deficiency Independent Learning SGD Break Plenary Student project Vitamins Deficiency Independent Learning SGD Break Plenary Student project Nutrition Management for Dyslipidemia and Hyperuricemia Independent Learning SGD Break Plenary Student project Food Supplement (Functional Food and Antioxidant) Independent Learning Class room WT Discussion room Class room Classroom WT Discussion room Classroom Class room Discussion room SUT Class room Class room Discussion room GNIP Class room Class room WT Discussion room Class room Class room SUT 5 Study Guide Clinical Nutrition & disorders 12th day Friday 18 Dec 2015 13th day Monday 21 Dec 2015 14th day Tuesday 22 Dec 2015 15th day Wednesday 23 Dec 2015 15th day Monday 28 Dec 2015 15th day Tuesday 29 Dec 2015 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-09.00 09.00-10.00 09.00-10.30 12.00-13.30 10.30-12.00 12.00-12.30 12.30-13.30 13.30-15.00 13.30-15.00 11.30-12.00 15.00-16.00 10.00-11.30 08.00-14.00 08.00-14.00 08.00-14.00 08.00-14.00 08.00-14.00 08.00-14.00 08.00-14.00 Udayana University Faculty of Medicine, DME SGD Break Plenary Student project Enteral and Parenteral Nutrition Independent Learning SGD Break Plenary Student project Medical Nutritional Therapy Independent Learning SGD Break Plenary Student project BCS Nutr assessment Screening/Food planning/Food planning BCS Nutr assessment Screening Discussion room Student Project Discussion room Final Examinatiom Class room Class room Classroom Discussion room WSR/ PRM Classroom Classroom SUT Discussion room Classroom Skill Lab Classroom TEAM Skill Lab Classroom TEAM TEAM 6 Study Guide Clinical Nutrition & disorders STUDENT PROJECT The aim of the student project in this block is to provide the opportunity for the student to learn more deeply on recent vitamin and mineral deficiency issues. In the mild situation these kind of problem usually asymptomatic or the symptom appears in different aspect of organ disease, but then it can give serious impact to the person who get it. For example folic acid deficiency in pregnant mother causing neural defect to the offspring. This situation often called as hidden malnutrition accordingly. Students shall disparted themself in group following the small discusiion group and then for the topic, they may choose one out of 16 topic of vitamin: A,B ,C,D,E,K or minerals macro: Ca and P, Mg, Na, K, Cl or Micro: Fe, Zn, I, Se, Mn. The report shall follow the scientific writing procedure produced by the university of Udayana. The Reference used in the the project shall be the most recent one, may be not older than 2010, except there isn’t any recent literature available to the particular topic. Fascilitators are requested to fascilitate and examine these project. REPORT FORMAT 1. Introduction: background and the evidence of malnutrition in certain topic 2. Basic knowledge: structure, food resources, need 3. Digestion and absorption 4. Metabolism in cell in connection to its spesific function i.e. immunity, sight, growth etc. 5. Nutritional therapy: how to process and serve it 6. Referrence REPORT SHALL BE SUBMITED WEDNESDAY, 23th. Dec 2015 Udayana University Faculty of Medicine, DME 7 Study Guide Clinical Nutrition & disorders LEARNING TASK 1st day INTRODUCTION OF THE THEME Case 1. Looking at Indonesian household study on health from 2007-2013 Indonesia has faced two burdens on nutrition over and undernourished which then called malnutrition. In one way we still facing chronic malnutrition shown as stuntet which will create problems on non communicable diseases in the future, in the other way the number of obesity and its related diseases are increasing . Furthermore, concerning health including nutrition we have other burdens those are teens and elderly, as the number of yiung adult as well as old people are also increasing. All these need more effort and budget to handle the problems. Poverty and natural disaster lead to increase nutritional problems especialy undernutrition. In other side, increasing wellness on small group of population lead to increase the risk of overnutrition and degenerative diseases. To minimize the risk of nutritional problem, optimal nutrition is needed to be applied in all population groups. 1. Explain, what does it mean by optimal nutrition, whilst human eating food? 2. Discuss how optimal nutrition can be apllied within individual as well as community 3. Explain, what causing people to get malnourished, under or overweight? 4. Mention stages of nutrition development and how to assess it? 5. What is the main nutritional problems in Indonesia and what is the arising nutrition problem today and its health risk? Case 2. A 5 years old girl, taken by her mother to the clinic (Health Centre). Her mother tells the doctor that she often got sick, it is nearly monthly. Her appetite also told as less. Looking at her growth monitoring chart, her weight falling down since she was 1 year. She got breast milk only 3 month because her mother has gone for a work and she is under her grandma cares when her parent is absent for work. She looks shorter to her mostly friend, she is less active for her age and irrtable. When they check her appetite, actually she eats heartlily Learning Task 1. What the appropriate information and assessment you should collect to support diagnose of the nutrition problem? 2. Looking at the sysmtoms above what illness might possible happenned to this girl and does it a reversible disease? 3. Should you think that it is a reversible disease, what is your advise to reverse her problem? 4. Beside nutrition factors, what is the others contributing factors might influence these conditions? Udayana University Faculty of Medicine, DME 8 Study Guide Clinical Nutrition & disorders 2nd day NUTRITION AND THE LIFE CYCLE Case Young mother come to your private clinic with her 6 months old girl infant. She complains that her infant’s weight gain was different with the neighbor’s one. She gives exclusive breastfeeding for her baby and she ask you when she must start to give solid foods? Learning Task 1. What is the meaning of exclusive breastfeeding and how long should it be given? 2. How to start solid foods, when to start solid foods and what kind of foods should be given to start with the solid food in infant feeding practice? Self-Assessment 1. Describe some of the nutrient and immunological attributes of breast milk. 2. Describe criteria would you use in selecting an infant formula. 3. Describe when an infant is ready to start eating solid food. 4. List foods that are inappropriate for infants and discuss why they are inappropriate. 5. List strategies for introducing nutritious foods to children. 6. Describe changes in nutrient needs from childhood to adolescence. 3rd day WELL BALANCE DIET Case 1. A young athlete 19 years old, height 178 cm, weight 70 kg. wants to maintain his ideal body weight as well as performance. He practice as athelete everyday with vigorous activity in the afternoon. After calculating his energy need, he is dicided to get 3000 kcal perday Learning Task : 1. Calculate the macronutient (carbohydrate, protein and fat) need following to his energy need and to get balanced diet. 2. Put your calculation into meal frequency include snack 3. Translate into food stuff that shall be given to meet his need 4. Discuss whether he needs special food before, during and after training. 5. Discuss whether he need an extra supplement to add his intake, and what supplement is best to be given to him. Case 2 A 26 years old woman, have just married, weight 54 kg, and height 160 cm, come to obstetric clinic to ask for advice on maintaining healthy pregnancy. She is worry of falling into nutritional deficiency when she get and during her pregnancy. Therefore, to prevent it she needs as many as information and advises on how to keep the optimal fetal growth and optimal nutrition status of pregnant and lactating mother. Learning task. 1. Calculate energy requirement of pregnant woment within 1st, 2nd, and 3rd trimester of pregnancy 2. Translate the total energy requirement of pregnant women in the all trimester into daily foodstuff. Make sure that the composition is appropriate to the requirement of balanced diet Udayana University Faculty of Medicine, DME 9 Study Guide Clinical Nutrition & disorders 3. What kind of protein resources is better to be used to get an optimal nutrition in the pregnancy? Explain why is it so 4. In menu planning, split all foodstuff into three main menu (breakfast, lunch and dinner) and two snack? 5. To optimize the nutrient availability what kind of foodstuff should be included in the menu? 6. If any case you find nutrient deficiency in the daily food intake, what suggestion shall be given to prevent and reverse it? Give the reason of your particular suggestion! 7. What shall you do to fill adequately all nutrient intake, both the quality and the quantity ? 8. For maintaining optimal infant growth and healthy mother, what kind of food are selected to the mother? 9. List and explain the steps that have to be done before planning a meal 10. To facilitate you to plan an adequate diet, you need some tools such as RDA (Recommended Daily Allowance), and Food Exchange List. Describe the adventage and disadvantage of both these two tools 4th day INFANT AND CHILDREN FEEDING PRACTICE Case Young mother come to your private clinic with her 6 months old girl infant. She complains that her infant’s weight gain was different with the neighbor’s one. She gives exclusive breastfeeding for her baby and she ask you went she must start to give solid foods? Learning Task 3. What is the meaning of exclusive breastfeeding and how long should be given? 4. How to start solid foods, when to start solid foods and what kind of foods were given at the first time? Self-Assessment 7. Describe some of the nutrient and immunological attributes of breast milk. 8. Describe criteria would you use in selecting an infant formula. 9. Describe when an infant is ready to start eating solid food. 10. List foods that are inappropriate for infants and discuss why they are inappropriate. 11. List strategies for introducing nutritious foods to children. 5th day OBESITY AND WEIGHT MANAGEMENT Case 1. Suharni, 27 years old, has got her gained weight since 4 years ago when she delivered her baby. Before pregnant her weight was 55 kg while her heigt was 160 cm. When she was pregnant, her weight increase 16 kg, and now her weight is 80 kg. She wants to have baby and she has been trying to do it unsuccesfully since one year ago. The obstetricus suggest her to reduce her weight, before trying it again. Learning task: 1. Count Suharni’s Body Mas Index before and after she gain weight and her nutrition status base on her BMI. 2. Discuss what is happening on her untill she gain her weight that much 3. What measurement need to be added to diagnose such condition above 4. Discuss the laboratory tested need to be carried out to distinguish whether she got the comorbidity or not Udayana University Faculty of Medicine, DME 10 Study Guide Clinical Nutrition & disorders 5. Theoritically what is the cause for obesity 6. Should She has to reduce her weight what she need to do. 6th day PRIMARY PROTEIN and ENERGY MALNUTRITION Case 1. A 28 years old man, height 178 cm, and 24 years old woman, height 164 cm, want to maintain their ideal body weight. Both of them are in moderate activity. Learning task 1. For the two people, calculate the Ideal Body Weight, energy requirement, energy intake to meet energy balanced Note: Total energy output is the summary of your’s body three uses of energy: a) Resting metabolic rate (RMR) b) Thermic effect of food (TEF) c) Physical activity a) RMR (use general formula) : Women : 0.9 kcalories/kg bb/hr Men : 1.0 kcalories/kg bb/hr b) TEF : 10% of total energy intake c) Physical activity Average activity level Energy cost (% or RMR) Sedentary 20 Very light 30 Moderate 40 Heav 50 d) Calculate Total energy output : Total energy output (kcal) = …..(RMR) + ….(TEF) + …..(Physical activity). 2. Calculate the Carbohydrate, Protein and fat composition to get a healthy diet. Case 2. In a party, there will be many kinds of food will be served. Mostly of those foods will comprise of animal base food such as pork, beef and or fish and cooked in several kind of menu Learning task. 1. If someone always eat a big portion of meet but less fish, what kind of fatty acid will be eaten more? What is the type of fatty acid will be in the pork and the beef? 2. What is the impact of such fatty acid to the health if daily menu consist of mostly fatty meat? 3. What kind of fatty acid are composed in the fish? 4. If some one eats fish more frequent, what is the beneficial effect of fish fat to the health? Explain your reason! 5. Compare saturated, monounsaturated, and polyunsaturated fatty acids in term of their : a) chemical composistion, b) effect on health, c) usuall food sourches. 6. Describe the meaning of P:S ratio of fatty acid and the ideal composition 7. Name the essential fatty acids. Why they are called essential? What will happen if the essential fatty acids are in a short supply? What suggestion should be given in this situation? 8. Differentiate the clinical benefit of essential fatty acid between omega-3 and 6 9. What are the potential problems associated with excess amount of eating fat in generall? Udayana University Faculty of Medicine, DME 11 Study Guide Clinical Nutrition & disorders Case 3. A 60 years old vegetarian man, his daily meal consist of sereal, soybean, spinach and some supplement and never take milk, egg nad other animal base food Learning task. 1. What your opinion about the quality of protein intake? 2. How does the healing process of the injured tissue in vegan people? 3. If pregnant women is a vegan food pattern what the the possibility risk might happen to the pregnancy (mother and fetal)? 4. For optimal growth and development, the body need good quality of protein. Why? 5. Explain the kind of protein in the food refer to the amino acid contained? 6. What is the meaning of essential amino acid, conditional essential amino acid 7. Define the reference of protein? 8. What does it mean by biological value of protein? Explain the biological value of different food protein resources? 9. Explain the term protein-sparing effect. 10. List and describe factors that affect the need on dietary protein! 11. What does it mean by nitrogen balance? How does it relate to protein turn over 7th day SECONDARY PROTEIN and ENERGY MALNUTRITION Case 1 A man age 35 year old has lost his weight since two month ago. His previous weight was 65 kg and his height is 172 cm, but now his weight is 48 kg. He also suffer from chronic diarrhea and coughing and just very recently his cough followed by blood split. He has had lost his appetite since he felt sore in his mouth and throat 1 month ago. He works as a tour guide but beside that he often sell his body to satisfy his client lust. Learning task 1. Mention what is happening nutritionally to this man 2. Discuss What causing him loose his weight so quick 3. Decribe indicators used to pictures clearly his situation 4. Discuss can we proposed him to get his normal weight again 5. Explain the principal of food intevention that can be given to Him Case 2 Beny aged 20 months was born in only 2000 grams of weight though he born under aterm pregnanacy. Her mother was also very thin when carrying on him. He got breastfed but not exclusive since is also working in the field to support the family life budget. Now his weight is 9 kg (average weight for his age is 11,8 kg). He often get ill and in the daily life he is very irritable. Learning task 1. Mention what is happening nutritionally to this infant 2. Discuss risk factors causing him fall into this situation 3. Discuss the progonsis of his particular problem short and long termly 4. Explain the principle of nutritional approach/therapy of this infant Udayana University Faculty of Medicine, DME 12 Study Guide Clinical Nutrition & disorders 8th day MINERALS DEFICIENCY Case A 20 years old male suffering from electrical burns since one month ago. Food intake has been declining due to lack of appetite. Suffered burns not healed so it still looks wet. Learning task. 1. What kind of mineral might be deficient in this case 2. What other symptoms and signs shall be found out in such cases? 3. What kind of food should be consumed as well as avoided to reverse the condition? 4. Describe the basic concept of essentiality in mineral (trace element) 5. Describe the action (metabolism), function, clinical application, RDI and food resources of major mineral 6. Describe factors that influence the bioavailability (promoter and inhibitor) and absorption of particular mineral 9th day VITAMINS DEFICIENCY Case An old lady 65 years old can no longer walk properly since she suffer from bow leg. She has seen a doctor and was told to have exposed with sun rays in the morning that she has rarely had it before because of worryness to get dark skin, and also she was ask to drink milk and some fruit mostly avocado. Learning Task 1. Mention the vitamin is deficient in this old woman, and explain the risk factors that bring people to geat it. 2. What this disease is called when it happened in older people as well as the young one 3. Explain symptom and sign of this particular vitamin deficiency either in older people and in young children 4. What kind of food should be consumed to reverse the condition? 5. Describe the definition and the basic concept of vitamins 6. Describe the basic concept of the difference between water and fat soluble vitamins 7. Describe the action, function, RDI, clinical application, side effect and food resources of fat soluble vitamins (A,D,E,K) 8. Describe the action, function, RDI, clinical application, side effect and food resources of water soluble vitamins (B and C) 10th day NUTRITION MANAGEMENT FOR DYSLIPIDEMIA AND HYPERURICEMIA Case Boby 35 year old visits a doctor because he feels he gets heavy chest, feels weak and pain mostly in his ankle. He has suffer from it for about one week. He is 120 kg weight and 170 height. He likes eating out and very lazy to do excercise. From his blood test, he finds out that his blood cholesterol is 300 mg/l and the LDL cholesterol is 200 mg/l and the HDL is 30 mg/l. The triglyceride is 400 mg/l and the uric acid is 9. Udayana University Faculty of Medicine, DME 13 Study Guide Clinical Nutrition & disorders Learning task 1. Diagnose the situation of this patient 2. Calculate the atherogenic index of this patient 3. Discuss the nutritional approach for this patient 4. Discuss what suggestion shall be given to the patient to get better result 11th day MEDICAL NUTRITION THERAPY Case A 55 years old male was hospitalized to undergo chemotherapy series II nasopharyngeal cancer. He looked very thin and weak. Decreased food intake due to no appetite. He could not eat solid food and drink only milk. He lost 15 kg of weight in 2 months with height 170 cm. The current weight is 40 kg and upper arm circumference of 15 cm. Laboratory results obtained Hb 9 g/dL and albumin 2.5 g/dL Learning task 1. To confirm the patients diagnose, what kind assessment you have to do? 2. To meet nutrition need of the patients, what other information you need for appropriate nutrition support? 3. What route of feeding and diet should be considered to promote healing? 4. What kind of supplement to be added to the daily menu of the patient? What is the reason? 5. How do you arrange the frequency of daily food intake? 12th day FOOD SUPPLEMENT (FUNCTIONAL FOOD and ANTIOXIDANT) Case 1 A 30 year old woman is a very active bank worker. She also works part time and takes a full load of duty, she is always on to go often grabbing something quick to eat like fast food or skipping meal altogether. Never the less, she feels confident her health will not suffer because she takes a daily vitamins and minerals supplement. Learning Task 1. Is a food supplement warranted in this case? 2. Why or why not? 3. What is your suggestion for the patients? Case 2 A 50 year old man, come to consult a doctor. Currently he is suffering from hypertension stage 1 and hypercholesterolemia. On physical examination found that body weight 85 kg, height 165 cm, and abdominal circumference of 100 cm. In addition to taking medication given by doctors, he also wants to consume omega 3 fatty acids, garlic supplements and vitamin E after reading an article. She says that garlic supplements claim to lower blood pressure, omega-3 fatty acids have antiinflammatory properties and Vitamin E is good for the heart among other benefits. Udayana University Faculty of Medicine, DME 14 Study Guide Clinical Nutrition & disorders Learning Task 1. Are all supplements warranted in this case? 2. Why or why not? 3. What is the side effect of the supplements? 4. What is your suggestion for the patients? 13th day ENTERAL AND PARENTERAL NUTRITION Case A 25 years old young man, admitted to the intensive care unit with multiple trauma due to motorbike accident. On patient examination, it was found to have GCS 8 with respiratory depression. The patient was normotensive 130/80 but tachycardic (118 beats per minute). Abdomen was not distended and bowel sounds were present. A nasogastric tube was placed with a return of 200 mL of clear gastric juice. A left femoral fracture and multiple superficial contusion were noted with no evidence of external bleeding. The patient was placed on a ventilator and resucitated. Laboratory data Abdominal series : Nasogastric tube in stomach, no bowel distension, no ileus. Chest radiography : without abnormalities Extremity rontgen : left femoral fracture CT scan of head : cerebral edema without intracranial hematoma Body composition Height : 183 cm Actual body weight : 85 kg Learning Task a. What is the preferred route of access for nutritional intervention, if the gut is intact and functional? b. How can you prevent tube feeding complications? Self Assessment 1. Describe benefits of enteral feeding for gastrointestinal physiology and function! 2. Describe indication and contraindication for nasoenteric tube placement! 3. Figure out common sites of inserting Central Venous Access! 4. What is main indication for parenteral nutrition Udayana University Faculty of Medicine, DME 15 Study Guide Clinical Nutrition & disorders ABSTRACTS INTRODUCTION of THE THEME Abstract Indonesia recently is in transition of epidemiologic periode. Its mean that Indonesia has both nutrition problem, undernutrition as well as overnutrition. Decreasing in undernutrition problem (protein energy malnutrition, nutrition anemia, vitamin A deficiency, iodine deficiency) and infectious diseases, coincindence with increasing prevalence of overnutrition and degenerative disease (type 2 of diabetes, heart disease, hypertension, gout, osteoporosis, cancer, etc). Its has been known that nutrition is closely related to disease entity mainly infectious and degenerative diseases. Appropriate nutrition intervention is needed for successful treatment of the diseases. The medical nutrition therapy should be individualized by providing optimal nutrition therapy to optimized the nutrient availability, absorption, transportation, utilization and its effects. To meet the optimal nutrition therapy, the student need a broad knowledge about : 1. The function of nutrient and its influence to health and diseases and the food sources 2. Principle of well balanced diet and menu planning 3. Simple nutritional assessment (Dietary, anthropometric, biochemical and clinical sign) 4. Pathophysiology of nutritional deficiencies and excess 5. Concept of medical nutrition therapy (MNT) In hospital based, medical nutrition therapy is part of health care team, consist of physician incharge and nutrition team. Nutritrition team are consist of medical/clinical nutrition specialist, dietitian, nurse, and include patient and family. At the end of this study, the student is expected to know the role of optimal nutrition in healing of diseases and promoting health PRIMARY PROTEIN and ENERGY MALNUTRITION Abstract Carbohydrate as sourches of energy for human bodies. Human bodies need adequate amount of energy daily to promote and maintain optimal health. There are several type of carbohydrate both refine and nonrefine that compose daily product widely spread include in Indonesia. It has been known that refine carbohydrate is related to degenerative diseases which are increasing in the last decade. So, increasing intake of non-refined or whole grain carbohydrate sources give a protective effect to the degenerative diseses. Other type of carbohydrate has been identified has protective effect for health namely low and high glycemic index of carbohydrate. Fat as sourches of energy more efficiently than carbohydrate. Fat has benefit and bad effect to health according to fatty acid containing in food (meat, fish, grain and others). So an adequate fat intake and appropriate ratio of saturated and unsaturated fatty acid is play a role in promoting and maintaining optimal health. Protein as a body building is important to maintain optimal biologic function of cells (growth, regeneration, reproduction, etc) to promote and maintain optimal health. To achieve optimal health, good quality of protein intake of animal sources should be consumed in adequate amount daily. Objectives At the end of this session, student must be able to 1. Describe the type, function and sources of carbohydrate, as well as its effect to health. 2 . Describe the type, functionand sources of protein as well as the effect to human health. Udayana University Faculty of Medicine, DME 16 Study Guide Clinical Nutrition & disorders SECONDARY PROTEIN and ENERGY MALNUTRITION Abstract PEM is a condition due to lack or deficit intake of carbohydrates, lipids, and protein from diet. These conditions signed by mobilized or oxidized all of energy source in the body. The impacts of mobilized energy are reduce body weight (fat, and muscle mass), reduce metabolic rate. Natural history of disorder innisiated by light, moderate and the last severe PAM. Light and moderate PEM could usually handled significantly by nutrition support. Severe PEM always followed by clinical complication with followed by some diseases, so the management of the condition should be need hospitalized beside nutrition care. PEM in child bearing period could disturb growth and development. In adult PEM decreased health status, and risks to suffer from some both communicable and non-communicable diseases. VITAMINS DEFICIENCY Abstract Nutrients in food are grouped into two major group i.e. macro and micro nutrients. Macronutrients comprise of substances that give energy such as carbohydrate, protein and fat, while micronutrients comprise of vitamins and minerals. The human requirement for micronutrient is not as big as macronutrient even some minerals, the requirement is very small but though they are very essential as the human body can not produce it except vitamin D, and shall be accordingly included in the human food. Vitamins, according to its solubility, are classified into two very distinctive groups: fat soluble and water soluble. This separation is also made in consider to its effect on human body and metabolism even though they are working together in carrying out body function. Human will not be deficient in fat soluble vitamin i.e. vitamin A, D, E, and K, unless they are on fat free diet for a longtime, because fat is the main resources for fat soluble vitamins. In addition most fat soluble vitamins are stored in human body or organ, even vitamin D is produced by our body using the food we eat and helped by the ultraviolet from the sun. Unlike the fat soluble, the water soluble vitamins are not stored and always excreted out after being used through sweat, urine and stools, therefore human needs to intake it daily from their food. Some foods content previtamin in which the body will transform it into vitamin when it is ingested. Vitamin works specifically in human function. Though they have multiple roles and action in the human body, they are working independently but cooperatively with other nutrient to support body/organ function and because they are very specific their presence can not be substitute by others. Objective At the end of the study, the student is expected able to describe the type, funtions, effect to human health and food sources of each vitamin Udayana University Faculty of Medicine, DME 17 Study Guide Clinical Nutrition & disorders MINERALS DEFICIENCY Abstract Likewise vitamin, minerals also classified into two or even three group: major, trace element and some trace which the essentialities are unclear. The classification is made base on the amount needed by human body, while the major mineral requirement shall be equal or above 100 mg/day, the trace elements are below 100 mg. Major mineral comprise of Calcium (Ca), Sodium (Na), Potassium (K), Phosphorus (P), Chloride (Cl), Sulfur (S). The trace element are Iron (Fe), Iodine (I), Zinc (Zn), Copper (Cu), Manganese (Mn), Chromium (Cr), Cobalt (Co), Selenium (Se), Molybdenum (Mo), and Fluoride (F); and the unclear trace elements include Silicon (Si), Vanadium (V), Tin (Sn), Nickel (Ni), Cadmium (Cd), Arsenic (As), Aluminum (Al), Boron (B) There are some similarities between mineral and vitamins. The essentiality, unique role, interactions and its impact to chronic diseases are similar between mineral and vitamins but the structure, absorption (mode of absorption), classification, roles in the body, the amount needed and the stability are different. Objective At the end of the study, the student is expected able to : 1. Describe the funtions and effect to human health and food sources of each mineral 2. Explain the factors that influence the availability of mineral WELL BALANCE DIET AND MENU PLANNING Abstract Balanced diet is important in promoting health. Balanced diet is planned to replace in and balance to the daily energy expended. Balanced diet consist of all nutrient in adequate amount to fullfil person need. Factor determine energy expenditure are : age, sex, physical activity, special condition, temperature, illness, etc. To plan balance diet, several steps should follows : 1. Decide total energy requirement (energy expenditure) of individual or patients 2. Decide the composition of macronutrient appropriate for balanced diet 3. Use food composition table, food exchange list or nutrisurvei to translate energy required into daily food needed appropriate to balance diet. 4. Split daily foodstuff into 3 main menu (breakfast, lunch, and dinner) and 2 snack portion Objective At the end of the study, the sutend is expected : 1. Undertnad the concept of balanced diet and menu planning 2. Able to use food composition table or nutrsurvey package 3. Able to analyses nutrient content of diet by using food composition table or nutri-survei Indonesia 4. Able to plan menu appropriate to balance diet Udayana University Faculty of Medicine, DME 18 Study Guide Clinical Nutrition & disorders INFANT AND CHILDREN FEEDING PRACTICE Abstract Malnutrition is still high, especially in developing countries, such as Indonesia. Malnutrition has been responsible for two-thirds of death annually among children under five. Well over two-third of these deaths are associated with inappropriate feeding practices, mainly during the first year of life. Inappropriate feeding practices including low prevalence of exclusive breastfeeding, too early or too late beginning of complementary feeding, and nutritionally inadequate and unsafe of complementary foods. Malnourished children who survive are more frequently sick and suffer the life-long consequences of impaired development. Objective At the end of the study, the student is expected to be able to describe the feeding practices in infants and young children. NUTRITION MANAGEMENT FOR DISLIPIDAEMIA AND HIPERURECEMIA Abstract Dyslipidemia is condition of abnormality of blood lipid profile concentration. Lipid profile such as triglycerides, LDL-cholesterol usually higher, and HDL-cholesterol lower than normal condition. This condition usually due to the imbalance of diet, especially excess of carbohydrate and saturated fat. Usually, the disorder occurs in person with obesity. Diet management such as decreased carbohydrate and saturated fat diet. Diet contain omega 3-poly unsaturated fatty (n-3 PUFA), often use to normalized blood lipid concentration. Hyperuricemia, the condition increased blood uric acid concentration above the normal level. Uric acid is metabolic product of nucleic acid (purine, pyrimidine), that construct DNA. Hyperucemia could caused by lack metabolism of uric acid due to enzyme deficient, and or too much purine intake from the diet. OBESITY AND WEIGHT MANAGEMENT Abstract Recently obesity is counted as a disease which attack human body systematically. It is predominantly caused by over eating and less out put. However there are plenty of risk factors can influence or even support this situation. As it is said as a systemic disease, if it is not treated well, it can underly several kind of diseases especially non contagious disease. Even the qonsequence of having obesity, when the patient got a disease, it can perform more severe compare to non obese patient. Weight manajement shall be perform to obese patient with or without comorbid of any related disease. Objectives At the end of this session, student is able to: 1. Define obesity by using several kind of measurement 2. Explain the risk factors of overweight and obesity Udayana University Faculty of Medicine, DME 19 Study Guide Clinical Nutrition & disorders 3. Describe other kind of diseases where obesity is the underlying factor 4. Describe methods that usually used to reduce or manage weight NUTRITION AND LIFE CYCLE Abstract Nutrition is important to health and wellness throughout ones lifespan. Knowledge of changing nutritional requirements is important to deliver quality health care. The student will develop a diet plan for individuals in various life stages. All healthy people need the same nutrients during each life stage, just in different amounts. Infancy – Birth to one year; Childhood – one year to puberty; Adolescence – puberty to adulthood; Adulthood – last from adolescence to old age; and specially condition are Pregnancy and Lactation. Objective At the end of the study, the student is expected able to describe the characteristic of each life stage and nutrients requirement. MEDICAL NUTRITION THERAPY Abstract Medical nutrition therapy refers to specific nutrition procedure including assessment and intervention in the treatment of an illness, injury and disease condition. Medical nutrition therapy procedures define the level, content and frequency of nutrition service that are appropriate for optimal care and nutrition outcome. There are many component to medical nutrition therapy. Screening may be completed by a registered dietitian (RD), dietetic technician registered (DTR) or health care professional. Nutritional care process include assessment,establishment of client’s selfmanagement goals, development of a nutrtion plan, documentation, communication with the primary care provider, evaluation and reassessment and outcome measurements. Objectives At the end of the study, the medical student is expected to 1. Comprehend the step of medical nutrition therapy 2. Comprehend the medical nutritional care team is work together to promote patient healing and health. FOOD SUPPLEMENT (FUNCTIONAL FOOD/ANTIOXIDANT) Abstract Most people nowadays are aware that deficiency diseases can be cured, and that adequate intakes of essential nutrients can be assured either by taking purified nutrients as supplements or in fortified foods. By analogy, perhaps some of the benefits of a modern recommended diet could be obtained by taking supplements that contain the active ingredients of foods that may help to prevent diseases such as cancer, heart disease and osteoporosis. This would allow us to eat our preferred ‘unhealthy’ fat- and sugar-rich diet but still enjoy at least some of the health benefits of eating a more prudent diet. Udayana University Faculty of Medicine, DME 20 Study Guide Clinical Nutrition & disorders Dietary supplements could include food preparations designed to meet all or part of the nutritional and energy needs of invalids, sports drinks, slimming foods and hundreds of herbal medicines that can be marketed as dietary supplements. The term functional foods could include every fortified food and every food for which some sort of health claim has been made, such as most breakfast cereals. A few of the substances used as dietary supplements are also licensed medicines: some generic vitamins (vitamins A and D, folic acid and cyanocobalamin, vitamin B12); a multi-vitamin preparation designed to meet the needs of children; a fish oil preparation; and an iron and folic acid supplement intended for pregnant women. It is permissible to make medicinal claims for these products, for example that a fish oil preparation, lowers raised plasma triacylglycerols and so helps to prevent heart attacks and pancreatitis. Other fish oil preparations marketed as dietary supplements are not allowed to make such claims. Similarly, it is permissible to refer to an iron and folic acid supplement intended for pregnant women’s role in reducing the risk of babies being born with a neural tube defect but such claims are not allowed for other dietary supplements that contain folic acid. To get a medicine licensed can take up to a decade and cost many millions of pounds; this is why many manufacturers of nutrients, ‘natural substances’ and herbal preparations choose to market them as dietary supplements instead. This means that they are subject to legal regulations relating to food rather than to medicines. Anything which is taken orally and not classified as a medicine is, by default, classified as food. This has major commercial advantages for the manufacturer who not only bypasses the expensive and slow process of getting the product licensed but is also subject to the much less stringent legal regulations relating to food. It is illegal to sell food which is harmful to health and it is illegal to dishonestly describe or advertise a food. This means that although it is illegal to make false health claims for a dietary supplement it is the prosecution that must ‘prove’ a claim to be false, whereas a medicine must be shown to be safe and effective before it is licensed. People take supplements for a variety of reasons, such as to compensate for a perceived or potential inadequacy in the diet, to compensate for some perceived increase in need or defective handling of a nutrient, to treat or prevent non-deficiency diseases or to improve athletic performance. In many cases it is difficult to give a definitive answer or even a fairly confident answer to the question of whether supplements or functional foods are actually effective (or even safe). When assessing the effectiveness of a dietary supplement or functional food one must decide what measure or measures are to be used as indicators of success or failure. In some cases, one can monitor the effect of a supplement on the signs and or symptoms of a disease. Thus when dietary deficiency diseases were first being identified, one could confirm the beneficial effects of a vitamin or mineral by testing the effect upon symptoms and disease progression of purified supplements or foods rich in the nutrient. ENTERAL and PARENTERAL FEEDING Abstract Increase case admitted to the intensive care unit in uncocius condition need proper medical nutrition therapy to prevent undernutrition. For this condition the MNT route is enteral and/or parentral is prefered. For appropriate dicission the indication, energy and nutrient needed, choosing formula, route of nutrtional intervention shuld be considered. At the end of the study, student is expected to know the indication, benefit or risk each feeding formula and the complicatiom of eneteral and parentral feeding Udayana University Faculty of Medicine, DME 21 Study Guide Clinical Nutrition & disorders REFFERENCE 1. Halsted, C.H., 1992. Toward standardized training of physicians in clinical nutrition. Am J Clin Nutr; 56: 1-3 2. WHO, 2003. Diet nutrition and the prevention of chronic diseases. WHO tecnicval series Report. 916 3. William, S.W. and Schelenker, E. D., 2003. Nutrion and Health. Essential of Nutrition & Diet Therapy. 8th ed , Mosby, St Louis, Missouri,p 4-21; 45-214; 373-388; 408-434 4. Dinarto M., 2002. Tim Nutrisi, Gizi Medik Indonesia, 1: 7-8 5. Torun B. and Chew F., 1981. Protein Energy Malnutrition. In R, E. Berhman and R.M Kliegman., editors, Nelson Essential of Pediatrics.4th ed..Toronto; pp.983-988 6. Ross A.,C. 1981. Vitamin A and retginoids. In R, E. Berhman and R.M Kliegman., editors, Nelson Essential of Pediatrics.4th ed..Toronto; pp 306-324 7. Pronsky Z.M., and Crowe J.P., 2008., AssessmentFood-Drug Interaction. In Krause’s Food Nutrition Therapy. Ed. Mahan L.K., and Escott-Stump S., WB. Saunders., pp.432-452 8. Hathcock J.N., Rader J.L, 1999. Food Additives, contaminants, and Natural Toxins. In Modern Nutrition in Health and Disease, 9th ed. Williams & Wilkins, Baltimore. pp1837-1856 9. DEPKES RI, 2002. Pedoman umum Gizi Seimbang (PUGS) 10. WHO-Unicef, 2003, Global Strategy for Infant and Child Feeding, WHO Geneva Udayana University Faculty of Medicine, DME 22 Study Guide Clinical Nutrition & disorders ~ CURRICULUM MAP ~ Smstr Program or curriculum blocks 10 Senior Clerkship 9 Senior Clerkship 8 Senior clerkship 7 Medical Emergency (3 weeks) Special Topic: -Travel medicine (2 weeks) Elective Study III (6 weeks) Clinic Orientation (Clerkship) (6 weeks) 6 BCS (1 weeks) The Respiratory System and Disorders (4 weeks) The Cardiovascular System and Disorders (4 weeks) The Urinary System and Disorders (3 weeks) The Reproductive System and Disorders (3 weeks) BCS (1 weeks) Alimentary & hepatobiliary systems & disorders (4 Weeks) BCS (1 weeks) The Endocrine System, Metabolism and Disorders (4 weeks) BCS (1 weeks) Clinical Nutrition and Disorders (2 weeks) BCS (1 weeks) BCS (1 weeks) Musculoskeletal system & connective tissue disorders (4 weeks) Neuroscience and neurological disorders (4 weeks) Behavior Change and disorders (4 weeks) BCS (1 weeks) Hematologic system & disorders & clinical oncology (4 weeks) BCS (1 weeks) Immune system & disorders (2 weeks) BCS(1 weeks) Infection & infectious diseases (5 weeks) BCS (1 weeks) The skin & hearing system & disorders (3 weeks) BCS (1 weeks) Medical Professionalism (2 weeks) BCS(1 weeks) Evidence-based Medical Practice (2 weeks) BCS (1 weeks) Health Systembased Practice (3 weeks) BCS(1 weeks) Community-based practice (4 weeks) - BCS (1 weeks) Studium Generale and Humaniora (3 weeks) Medical communication (3 weeks) BCS (1 weeks) The cell as biochemical machinery (3 weeks) Growth & development (4 weeks) BCS (1 weeks) BCS(1 weeks) BCS: (1 weeks) BCS (1 weeks) Elective Study II (1 weeks) 5 4 3 2 1 BCS (1 weeks) Special Topic : - Palliative medicine -Compleme ntary & Alternative Medicine - Forensic (3 weeks) Elective Study II (1 weeks) Special Topic - Ergonomi - Geriatri (2 weeks) Elective Study I (2 weeks) The Visual system & disorders (2 weeks) Pendidikan Pancasila & Kewarganegaraan (3 weeks) Udayana University Faculty of Medicine, DME 23