NAME: _________________ LYMPHATIC AND IMMUNE SYSTEMS A macrophage engulfing 2 damaged RBC’s SONOMA VALLEY HIGH SCHOOL ADVANCED BIOLOGY SPRING 2013 SVHS ADVANCED BIOLOGY 2013-2014 LYMPHATIC SYSTEM AND IMMUNITY UNIT OUTCOMES: A) Be able to describe the origin of lymph: its makeup, and the role it plays in the body. (P.456) B) Be able to explain the function of lymph nodes found in parts of the body. (P. 458-459) C) Be able to describe several mechanisms of innate immunity against pathogens. (P. 459-460) D) Be able to describe several chemical means of nonspecific resistance against pathogens. (P. 460-461) E) Be able to describe why inflammation occurs and why it is important. (P. 461-462) F) Be able to define adaptive immunity and compare it to innate resistance. (P. 463-464) G) Be able to explain the relationship between antigen and antibody. (P. 465-467) H) Explain the functions that occur in cell-mediated immunity. (P. 467-469) SCHEDULE: Mon 4/28 A LECTURE: LAB: HOMEWORK: Lymphatic system Select topics Address outcomes A and B. Read 454-459 Wed 4/30 C LECTURE: LAB: HOMEWORK: Nonspecific resistance. Pathogen case study (packet) Address outcomes C and D. Read 459-462 Thurs 5/1 A LECTURE: Lab: HOMEWORK: Adaptive immunity work on project Address outcomes E and F in essay form. Read 463-467 Mon 5/5 A LECTURE: LAB: HOMEWORK: Cell and antibody-mediated immunity. complete Projects Early presentations Prepare for test. Complete outcomes G, H. Read 467-473 Wed 5/7 C Unit Test: Lymphatic system and Immunity Presentations Thurs 5/8 Digestive system Unit SVHS ADVANCED BIOLOGY LYMPHATIC SYSTEM & IMMUNITY SELF STUDY GUIDE 1) From pages 456-459 titled “Lymphatic System” be able to: A) B) C) D) E) F) G) H) List and explain three functions of the lymphatic system. Contrast interstitial fluid with lymph. Describe what causes lymph fluid to enter lymphatic capillaries. Explain how the circulatory system and its vessels differ from the lymphatic system and its vessels. Describe the role of lymph nodes found in various areas of the body. Explain what metastasis means and how it relates to the lymphatic system. Explain what the tonsils, spleen, thymus gland have in common. (Also describe their locations) Explain how the circulation of blood relates to the circulation of lymphatic fluid. 2) From pages 459-462 titled “Innate Immunity” be able to: A) Define “innate immunity”. B) Be able to discuss how mechanical factors such as skin (keratin), mucous membranes, epiglottis, flow of urine, the lacrimal apparatus, and saliva plays a role in nonspecific resistance. C) List and explain several examples of chemical factors that play a role in nonspecific resistance to pathogens. D) Explain what interferon’s are and how they play a role in nonspecific resistance. E) Explain what “complement”, transferrins, and antimicrobials are, and their roles.. F) Explain the role of natural killers. What types of white blood cells are natural killers? 3) From pages 461-462 titled “Inflammation” be able to: A) B) C) D) E) Define stress in regards to inflammation response. Describe four symptoms of an inflammation response. Name the three stages of inflammatory response. Summarize what occurs in each of the three stages. Explain how emigration and chemotaxis are related. 4) From pages 463-467 titled “Adaptive Immunity” be able to: A) B) C) D) Explain how specific resistance (adaptive immunity) is different from innate immunity. List and briefly describe the 2 types of immunity. Define antigen. Explain the relationship between antigen and antibody (Page 465) 5) From pages 463-473 titled “Adaptive Immunity” be able to: A) B) C) D) E) F) G) Describe what cells are involved in cell mediated immunity. (Contrast the two) Describe what must happen before they can attack a pathogen. Summarize the role of macrophages in the sensitization process. Explain the role of memory B cells. Contrast primary response and secondary response. Describe the actions of antibodies. Explain what ‘immunological memory’ is SVHS ADVANCED BIOLOGY CASE STUDY: PATHOGEN CASE STUDY NAME OF CONDITION: ______________________________ COMMON NAME OF PATHOGEN: ________________________ BINOMIAL NAME OF PATHOGEN: ______________________ TAXONOMY INFORMATION: PHYLUM NAME: ________________________ FAMILY NAME: _______________________ DESCRIPTION OF GROUP & OTHER MEMBERS OF THIS GROUP: PATHOGEN STRUCTURE: (INCLUDE PICTURES) PATHOGEN LIFE CYCLE: (INCLUDE PICTURES) HOW THE PATHOGEN AFFECTS THE BODY. TREATMENT & CURE: SVHS ADVANCED BIOLOGY Immunology Multimedia Project DESCRIPTION OF PROJECT: The Advanced Biology class will prepare a PowerPoint (or other multi-media) tutorial that will be used to instruct Lab Biology students regarding the immune system. Each group will prepare a 7-10 slide project regarding a segment of the immune system. On the last presentation slide, create a 5 question Quiz with answers provided. Citations slide in MLA format required for grading GROUP TOPICS: 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) Macrophages and Process of Phagocytosis Killer T Cell B cells and Antibody – Mediated Immunity T Cells and cell – Mediated Immunity Structure and Actions of Antibodies Acquired immunity Inflammation Nonspecific Defenses (Mechanical, Chemical, and Antimicrobial) Antigens and the Immune System (Including Viral Structure) Role of Lymphatic System (In particular Tonsils, spleen, and Thymus) Each topic that relates to a cell type should include the following: • Where cell is produced. • Life cycle of the cell. • Action of the cell. • Structure of the cell. CRITERIA FOR PROJECT All media presentations must meet the following criteria to be acceptable: A) B) C) D) E) Capable of running on the iMacs in science center room. Contain 7-10 slides. Contain pictures that relate to the topic being discussed.. Contain an animated quiz of at least 5 questions at the end of the program. Produced such that the content of Advanced Biology level can be explained at 10th grade Lab Biology Level. To receive a ‘B’ grade the PowerPoint presentation must contain one of the following. A) Contain a video segment from any source. B) Have your voice as a narration. C) Contain imported Music. To receive an ‘A’ grade the PowerPoint presentation must have two of ‘B” criteria above.