Unit 1 Introduction to Biology, Chemistry and Water. Test Friday Chapters. 1-3 pages 1-46 Chapter 1 Key terms Control Dependent variable Independent variable Hypothesis Replication Randomness Theory Experimental group Homeostasis Cell Organism Population Community Ecosystem Biosphere Evolution Atom Taxonomy Diversity Emergent property Objectives Diagram the heirarchy of structural levels in biology. Briefly describe the unifying themes of biology Explain how science and technology are interdependent. Distinguish between deductive and inductive reasoning. Write hypotheses meeting criteria given Design a controlled experiment while labeling parts. Analyze an experiment by determining and labeling parts. Chapter 2 Key terms Covalent bond Ionic bond Isotopes Ion Proton neutron electron trace element Polar bond non polar bond hydrogen bond half life Objectives State the four elements essential to life that make up 96% of living matter and four elements that make up most of the remaining 4%. Describe the structure of an atom Explain the significance of radioisotopes to biologists Compare and contrast ionic, polar covalent, nonpolar covalent, and hydrogen bonds. State the major components of the earths current atmosphere. Describe the early atmosphere as the earth formed. Chapter 3 Key terms Cohesion Surface tension Adhesion Capillary action Solvent Solute Solution Acid Base pH scale Buffer Heat of vaporization Specific heat Hydrophilic Hydrophobic Transpiration Objectives Describe how the unique physical and chemical characteristics of water make life on earth possible. Explain how water is able to form a hydrogen bond and why it is significant. Draw a water molecule and label its positive and negative delta charges. Explain the basis for the pH scale. Explain how a buffer works using the bicarbonate buffer system as an example Describe the causes of acid rain, and explain how it affects the fitness of the environment Unit2: Biochemistry and Enzymes Chapters 4, 5, and 6: Pages 48- 108 Lab 1: Diffusion and osmosis Chapter 4 Key terms Functional group amino group carboxyl group Isomer organic inorganic Objectives Be able to identify the functional groups Draw an amino acid Explain the role of Carbon in the molecular diversity of life Describe Urey-Miller experiment and its significance hydrocarbons phosphate Chapter 5 Key terms Polymer monomer carbohydrate starch Cellulose sugar monosaccharides disaccharides Sucrose lactose Condensation synthesis Hydrolysis Glycogen protein macromolecules Lipids Nucleic acids nucleotides amino acids glycerol Fatty acids unsaturated fats triglyceride saturated fats Glucose galactose maltose fructose Storage polysaccharides structure polysaccharides chitin Fats phospholipids steroids hydrophilic heads Hydrophobic tails peptide bonds variable R group hemoglobin Cholesterol denaturation protein conformation DNA RNA ribose deoxyribose nitrogenous base Pyrimidine purine nucleoside double helix Denature phosphodiester linkage Objectives Explain the analogy of a string of beads to the structure of a polymer Name and explain how macromolecules are synthesized and broken down. List the four major macromolecules and describe their structures. Draw an amino acid, glycerol, cholesterol, phospholipid, and nucleotide with detail. List key examples and functions of each of the macromolecules Compare and contrast starch, glycogen, and cellulose. the primary, secondary, Distinguish tertiary and quaternary structure of a protein. Explain the significance of protein conformation. Explain the book’s analogy of software and hardware to DNA and proteins. Compare and contrast the phosphodiester linkage and hydrogen bonds in a DNA molecule. Explain how the structure of each macromolecule accounts for its function. Chapter 6 Key terms Substrate Specificity Exergonic Activation energy Lab 2: Enzyme catalysis Lab 4: Plant pigments and photosynthesis Lab 5: Cell respiration Catalyst denature endergonic active site Enzyme metabolism exothermic cofactors Induced fit theory free energy endothermic coenzymes Competitive inhibitors feedback inhibition spontaneous rxn noncompetitive inhibitors Anabolism catabolism ATP ADP Allosteric regulators saturated phosphorylation Objectives Explain the relationship between free energy, entropy, enthalpy, and temperature in determining how a reaction progresses. Explain the induced fit theory Explain how enzyme activity is regulated by environmental conditions, cofactors, enzyme inhibitors, and allosteric regulators Sketch graphs of reaction/time and free energy/time for uncatalyzed reactions, enzymecatalyzed reactions, feedback inhibitor reactions, and allosteric enzyme reactions Discuss the effect of concentration of product, reactant and enzyme on reaction rate. Draw the structure of ATP Describe the significance of ATP and enzymes in cell function. Unit 3 Cell structure, Cellular transport, and Cell communication Chapters 7, 8, and 11 Pages 173-218 and ??????? Chapter 7 Key terms SEM TEM cytology cell Cell fractionation prokaryotic cell eukaryotic cell nucleolus Nucleus nuclear pore nuclear envelople chromosomes Chromatin ribosome vesicles vacuoles ER/endoplasmic reticulum lysosomes golgi apparatus plasma membrane Smooth ER rough ER phagocytosis perioxisomes Mitochondrion chloroplasts christae plastids Chromoplast amyloplast thylakoids grana Stroma cytoskeleton microtubules centrioles Flagella cilia 9 + 2 pattern basal body Microfilaments cyclosis intermediate filaments cell walls Plasmodesmata glycocalyx gap junctionss tight junctions Desmosomes organelle Objectives Explain in your own words why cells must be small. Describe the structure and components of the nucleus. Explain the advantages and disadvantages of the SEM, TEM, and light microscope. Compare and contrast eukaryotic cells and prokaryotic cells Explain why compartmentalization is important in eukaryotic cells. Label cell parts and identify their functions. Distinguish the three types of plastids Describe the structure, monomers, and functions of the three parts of the cytoskeleton. Describe the structure of flagella and cilia. Explain how cells communicate with their neighbors. Describe the three types of vacuoles and their list their functions Describe the structure of the eukaryotic ribosome, mitochondrion, and chloroplast. Describe the current model for the endomembrane system and how it provides for transport and recognition. Chapter 8 Key terms Selectively permeable fluid-mosaic model cholesterol hydrophilic Hydrophobic diffusion osmosis active transport Passive transport facilitated diffusion water potential concentration gradient Osmotic potential hyperosmotic hypoosmotic hypertonic Hypotonic isoosmotic isotonic proton pump Sodium potassium pump cotransport phagocytosis pinocytosis Exocytosis endocytosis dialysis plasmolysis Turgid phospholipid bilayer integral proteins peripheral proteins Glycolipids glycoproteins water potential Objectives List and describe mechanisms by which substances cross the plasma membrane. Describe the process and people’s work by which the fluid mosaic model was constructed. List and describe factors affecting the flexibility and strength of the plasma membrane Describe transport proteins and how their structure determines what type they are. Explain how the energy from ATP is harnessed during active transport. Describe the importance of the plasma membrane being able to maintain homeostasis in the cell Describe how organisms of different types can maintain osmotic integrity in their various environments. List and describe the molecules in the plama membrane that allow it to perform its various functions. Unit 3 11 days Chapter 6, 9,10 Test Thursday Read pages 97-108, 173-178,188-195,199-206,214-218 (39 pages) Chapter 9 Key terms Redox cellular respiration Kreb’s cycle glycolysis Electron transport chain pyruvate lactic acid acetyl CoA NAD FAD electron carrier fermentation Obligate anaerobe facultative anaerobe obligate aerobe chemiosmosis Oxidative phosphorylation substrate level phosphorylation Alcohol fermentation lactic acid fermentation lactic acid Objectives Explain why facultative anaerobes like us are advanced evolutionarily. List and briefly describe the three major steps in cellular respiration, indicate where they occur in the mitochondrion, and what are the products of each step. Compare and contrast fermentation and cellular respiration. Write an overall reaction for cellular respiration and fermentation Trace the oxygen, carbon and hydrogen through the process of cellular respiration. List what is reduced and what is oxidized in cellular respiration. Describe phosphorylation and how it is related to ATP doing work. Explain how feedback inhibition causes muscle cells to revert back to fermentation when insufficient amounts of oxygen are present. Explain how lactic acid affects the muscles and how lactic acid fermentation might of evolved to help and protect the organism. Chapter 10 Key terms Photosynthesis light dependent rxn light independent rxn chlorplast Chlorphyll Calvin cycle spectrophotometer pigment Xanthophyll Carotene chlorphyll a chlorophyll b Photocenter I Photocenter II carbon fixation heterotroph Autotroph accessory pigments G3P RuBP C3 plants C4 plantss CAM plants stomata Photorespiration photoautotrophs chemoautotrophs chemosynthesis Objectives List and describe the two major steps of photosynthesis, where they occur in the chloroplast, and what the products are for each step. List the advantages and disadvantages of C3, C4, and CAM plants. Trace the carbon, hydrogen and oxygen through the process of photosynthesis. Discuss the evolutionary relationship between photosynthesis and the central vacuole of plant cells. Explain the role of water in photosynthesis. Compare and contrast the processes of photosynthesis, cellular respiration, and fermentation Explain why the number of mitochondria and chloroplasts vary in different types of cells and locations in the organism. Unit 4 Mitosis, Meiosis, Heredity 7 days (Test on Friday Sept. 3) Chapters 11-14. Reading: 221-224, 226-229, 234-237 (except diagrams on page 235 and 236), 248-249, 252254, 284-288, DO all self quizzes and problems for chapters 11-14. Read the double helix. Chapter 11 Terms Binary fission Centromere Mitosis G1 phase Interphase Anaphase Centrioles Metastasis Cleavage furrow Density dependent inhibition Chromatin Kinetochore Cytokinesis G2 phase prophase telophase cancer benign tumor cell plate protein kinases Chromosome Chromatid Cell cycle S phase metaphase spindle fibers malignant tumor contact inhibition cell culture Questions How does cell division differ for eukaryotes and prokaryotes? How does cytokinesis differ for plant cells and animal cells? List the stages of the cell cycle and what occurs in each stage using terminology given. What conditions lead to cancer? How does mitosis provide continuity and ability to change at the same time? Differentiate chromosomes, chromatids, and chromatin. Do the self quiz. Go to http://www.biology.arizona.edu Find the online onion root tips project. Identify 30 cells and print your findings. Do challenge question 1 a-c on page 239. Chapter 12. Meiosis Gamete Tetrad Alternation of generations Locus Somatic cells diploid (2n) homologous chromosomes crossing over zygote sex chromosomes asexual reproduction haploid (n) synapis chiasmata karyotyping parthenogenesis sexual reproduction Questions Describe the differences between mitosis and meiosis. List and describe three factors that contribute to increasing the genetic variation in a population. What is the significance of meiosis? Discuss the advantages and disadvantages of asexual and sexual reproduction. Do the self quiz at the end of chapter 12. Answer question 2 in challenge questions on page 257. ,