Name__________________________________________________Period_____________ 1 Antonelli – Biology – Cell Cycle and Mitosis Tutorial Cell Cycle and Mitosis Tutorial Please go to http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycl e/main.html Read through the information and answer the questions below. Questions on this sheet are in italics. Click “Next” when you complete each page. DNA Basics What is DNA and where is it stored? 1. What is chromatin? 2. What is the difference between chromatin and chromosomes? 3. Why is chromatin extended during interphase? 4. Describe the relationship between chromatin, histones and nucleosomes? 5. What is DNA? 6. What is the process of mitosis designed to do? The Cell Cycle 1. What is the cell cycle? 2. What are the stages of the cell cycle and what do the cycle abbreviations stand for? 3. Sketch the circular diagram that depicts the cell cycle and its stages. Be sure to indicate each stage on the diagram.. 4. What is cancer? 5. What is p53? Mitosis What is (and is not) mitosis? 1. Define “mitosis”. 2. Is interphase part of mitosis? consist of? What does interphase Name__________________________________________________Period_____________ 3 Antonelli – Biology – Cell Cycle and Mitosis Tutorial Interphase and mitosis 3. Describe each of the following phases of the cell cycle and draw a rough sketch of the appearance of the cell in each phase. a. Interphase b. Prophase c. Prometaphase and Metaphase d. Anaphase e. Telophase f. Cytokinesis Watch the flash mitosis animation to see all of the phases in sequence. Go to http://www.cellsalive.com/mitosis.htm and watch the mitosis animation there. You can click on each phase to get a still picture of the phase. Compare these pictures to the sketches you drew above and revise your drawings as necessary. Now go to http://www.cellsalive.com/cell_cycle.htm and watch the cell cycle animation. Write a brief summary of each phase below: Name__________________________________________________Period_____________ 5 Antonelli – Biology – Cell Cycle and Mitosis Tutorial Interphase o G0 o G1 o S o G2 o M When are there checkpoints during the cell cycle? you think is the purpose these checkpoints? What do Return to http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycl e/problems.html Answer the self-quiz questions to test your knowledge of mitosis. After you have gone through the self-quiz, go to http://www.biology.arizona.edu/cell_bio/activities/cell_cyc le/cell_cycle.html Read through information on the page and then click “next”. This page will allow you to review the stages of mitosis. Click “next” when you have finished reviewing the stages. Use the following table for the assignment described on the page. After you have read the description of the assignment, click “next”. At the top left of the page is an image of an actual onion root cell at some stage in the cell cycle. Click on the phase in which the cell belongs. The software will give you feedback on how to proceed. Record how many cell images were in each particular phase and then calculate the percent of cells in that stage. Enter this information above. Based on the data in the table, what can you conclude ? In which stage do you think cells spend most of their time?