Ch. 10 Experimental Designs Subgroups: 1. Between subject design a. Subjects assigned to independent groups using randomization 2. Randomized block design a. Subjects classified according to attribute variable and then randomized to treatment groups 3. Within-subject design or repeated measures design a. one group of subjects is tested under all conditions and each subject acts as his own control b. considered series of trails each with a single subject 4. Single-factor or one-way design or multi-factorial a. Experimental designs can also be described according to the number of independent variables or factors 5.Pretest-posttest control group design 6. Mixed design a. Study incorporates two independent variables, one repeated across all subjects and the other randomized to independent groups Ch. 11 Quasi-experimental Will LACK random assignment OR comparison groups OR both Used as reasonable alternative to randomized trial design Subgroups: 1. One group pretest-posttest design a. One set of repeated measures taken before and after treatment on one group of subjects 2. Time series design a. Multiple measurements before and after treatment used to study community interventions and policy changes 3. Nonequivalent pretest-posttest control group a. Subjects are self-selected due to research situations in social, clinical, and behavioral sciences b. Subjects not assigned to groups randomly- one treatment group, one control group 4. Nonequivalent posttest-only control group design a. Includes any number of treatment levels, with or without control group b. Uses existing groups who have and have not received treatment Ch. 12 Single-Subject Designs Must have a collection of repeated measurements of a behavioral response over time Must have 2 testing periods or phases: baseline and intervention Subgroups: 1. Withdrawal design a. Includes a second baseline and maybe a second intervention 2. Multiple baseline designs 3. Alternating treatment design 4. Multiple treatment design Chapter Outline 13 Observational-study that does not involve an intervention or a manipulation of an independent variable. Exoploratory research-research that has as its purpose the exploration of data to determine relationships among variables RETROSPECTIVE AND PROSPECTIVE RESEARCH: Prospective research- study designed to collect data following development of the research question Retrospective research- study that analyzes observations that were collected in the past. LONGITUDINAL AND CROSS-SECTIONAL RESEARCH: Longitudinal Research- study designed to collect data over time, usually the purpose of describing developmental changes in a particular group. Cross-Sectional Research- study based on observations of a different age or developmental groups at one point in time, providing the basis for inferring trends over time. CORRELATION AND PREDICTION: Correlation- measure of the degree of association between variables. Correlational research- descriptive research approach that explores the relationship among variables without active manipulation of the variables by the researcher. Predictive Correlational Study- study designed to predict a behavior or response based on the observed relationship between the behavior and other variables Regression Analysis- a statistical procedure for examining the predictive relationship between a dependent (criterion) variable and an independent (predictor) variable CASE-CONTROL STUDIES: o Selection of Cases and Controls Selection of Cases: a. Population based study- study that obtains a sample of cases from the general population of those with the disorder b. Hospital based study- study in which cases are obtained from patients in a medical instituiton. Selection of Controls- controls can be selected from several sources. They are often recruited from the same hospital or instiutution as the cases, from those admitted for conditions other than the disease of interest. COHORT STUDIES: Cohort study- an observational study design in which a specific group is followed over time. Subjects are classified according to whether they do or do not have a particular risk factor or exposure and followed to determine disease outcomes. Prospective- study designed to collect data following development of the research question Retrospective- study that analyzes observations that were collected in the past. EVALUATING CAUSALITY IN OBSERVATIONAL STUDIES: Observational study-study that does not involve an intervention or manipulation of an independent variable. Dose- response relationship- provides evidence for causality. This means that the severity of the disease can be associated with varying levels of exposures. METHODOLOGICAL RESEARCH: RELIABILITY AND VALIDITY : Methodological Research- research designed to develop or refine procedures or instruments for measuring variables, generally focusing on reliability and validity. o Reliability Questions Testing the Rater o Validity Questions HISTORICAL RESEARCH Historical Research- research that seeks to examine relationships and facts based on documentation from the past. Reliability and Validity: a. External criticism- establishing the authenticity of data. b. Internal criticism- questions the truth or worth of the material’s content within the context of the research question. Secondary Analysis- an approach to research involving the use of data that were collected for another purpose, usually for the purpose of testing new hypotheses.