Introduction to Cell and Molecular Biology, BIOL 190 Syllabus Fall, 2007 Great Basin College, Science Department Instructor: Gregory Schmaltz, Ph.D. Office: PVC Main Office, Room 101B Phone: 775-727-2005 Email: gregorys@gwmail.gbcnv.edu Office Hours: M & W 17.30-19.00 W 12.00-14.00 and by appointment. Method of Instruction: Live lecture and laboratory (Lectures and lab activities will be performed during both weekly class meetings). Classes on: Mondays & Wednesdays from 14.30 to 17.15 in room PVC 116 Text: Biology, Concepts & Connections. 5th ed. Campbell, Reece, Taylor, and Simon ISBN-10: 0-321-51244-8 Lab Manual: Laboratory Manual. Perry, Morton, and Perry. ISBN: 0-534-38025-5 Teaching/Lab Assistant: 0 Catalog Description: BIOL 190 Cell and Molecular Biology (4 credits) Welcome to Cell and Molecular Biology! In this course you will learn why athletes have cramps, how different low carb and low fat diets work (which is the best?), or why serious scientists make female students smell T-shirts worn for three days by male students. More generally this course will examine: 1) Structure and function of cells; 2) The major molecules of life and the composition and physiology of cellular organelles; 3) Cell metabolism, reproduction, and motility; 4) Gene function of both plant and animal cells; and finally 5) The origin of species and the basic principles of evolutionary theory. This is a survey course designed for the student intending to major in biology or another science. Such fundamental topics as cell biology, photosynthesis, respiration, genetics (both Mendelian and molecular), and evolution will be introduced. This course emphasizes basic concepts and theories as well as lab-based and experimental approaches to exploring questions in Cell and Molecular Biology. Empirical examples will emphasize vertebrate animals (including humans) and some examples will also involve bacteria, insects, and plants. Questions and discussion/debates are encouraged during lecture to prepare for the 4 course exams. Cell and Molecular Biology is a freshman level, introductory biology, laboratory science course required for biology and nursing majors, and students enrolled in the elementary education program. Additionally, it can fulfill the science requirement for most associate degrees at Great Basin College. This course is worth 4 credits, and is equivalent and transferable to all Nevada community colleges and universities. Biology majors are generally required to take a second semester in Organismal Biology, designated as Biol. 191 and offered here in the spring. No prerequisite. (Formerly BIOL 190, General Biology I) 1 Course Objectives and Expected Learner Outcomes: Major Objectives: Demonstrate a general knowledge of biological principles and processes (as per the 5 major points in the catalog description above). Meet the general education objectives (see below). General Education Objectives: Communication Skills: Students will have opportunity to demonstrate strong written communication skills via the laboratory report. Reading and listening skills will be heavily used in both lecture and lab. Oral skills are a key component of interaction with the instructor in lab. Critical Thinking: Quantitative skills will be required for key concepts in genetics, and mathematical operations will be assessed in exams. Reasoning and independent thought is required for successful completion of both the written report and lab practicals. Scientific understanding is of course at the heart of this course, which emphasizes the use of the scientific method in the development of key theories and principles of biology. Personal and Cultural Awareness: This course presents the evolutionary history of humans, as well as the place of human diversity in the context of biological diversity. As a consequence, a sense of the past is gained via evolutionary history, and human diversity demonstrates the biological underpinnings (or lack thereof) the individual in society. Personal Wellness: Both an introduction to genetics, cellular respiration and cancer are explicitly learned in this course. All of these topics give an understanding of key human health and wellness factors. Technological Understanding: Students will not merely acquire knowledge of the principles of biology, but also the technologies, observations and experiments that underlie them. Students will also directly manipulate a variety of technologies, including microscopes, respiratory manometers, and computer simulations. Minor Objectives: Utilize the scientific method to construct reasonable hypotheses and communicate effectively in a written form. Participate in limited laboratory skills and procedures. Apply lab safety skills. Examine the impact and ethical issues of science and technology on our lives and the global society. Determine the molecular and cellular causes of human diseases. Appreciate the art and beauty of nature and biological processes. 2 Measurement of Objectives: Learning and general education objectives will be assessed with three distinct tools. Lecture exams will consist of multiple choice questions and/or short essay questions that will test three types of knowledge: recall of factual information; definitions of terminology; and conceptual and integrative thinking. The written laboratory report will assess students’ written communication skills, as well as their conceptual understanding of a critical lab experiment. Laboratory practicals will emphasize recall of the various manipulative and study objects used in the exercises, as well as testing that the students understand the concepts and principles that were generated with these devices. In lab students will also learn how to use the metric system, the microscope, and other laboratory equipment. Students will participate in discussions of the impact of ethical issues of biology. Students will appreciate the art and beauty of nature and biology from colored photographs in the textbooks and lab experiments. Grading System and Policies: The grade for this course will be based on two components: performance in lecture; and laboratory. They will be weighted 75% for the lecture, and 25% for the lab. The lecture grade will be based on four, one hour exams, worth 100 points each. The lab grade will be based on two practical exams worth 50 points each, a written report worth 50 points and ten weekly quizzes worth 10 points each. I will not use a normal curve to adjust the grades. The grading scale is as follows: 90 - 100% = A 80 - 89% = B 70 - 79% = C 60 - 69% = D > 60% = F Excellent! Your doing super! Keep up the good work. Have you considered a career in the life sciences? Superior! Continue what you’re doing, but consider asking questions on the finer details in the text and lecture material. Adequate. You’ve got it under control, but don’t get complacent. Review your notes and the text carefully. Ask questions, either in class or in my office to clarify important topics. Danger zone. All is not lost, but you are at risk. You need to carefully work through the materials and resources available to you. Attend regularly, and work on your note taking skills. Make sure to either ask questions in class or come by my office for help. Failing. Definitely come to my office for a visit where we can work on a strategy for your improvement. Another way to look at the grading is: A = All major and minor goals achieved B = All major goals achieved; some minor ones not. C = All major goals achieved; many minor ones not. D = A few major goals achieved, but student is not prepared for advanced work. F = None of the major goals achieved. 3 All exams and lab practicals will be held on the dates listed in the syllabus. Any changes to that schedule will be announced in class well in advance. Missing an exam due to personal reasons or illness must be approved in advance if possible, or by contacting me within 24 hours of the exam in the case of emergency. Make up exams will be allowed and scheduled at my discretion. Lab practicals are difficult to set up. As a result, make up lab practicals will only be scheduled in unusual circumstances. In these cases the format of the exam may change. Do not miss lab practicals! Attendance will not be taken, but be advised: Regular attendance is the single most important thing you can do to get and maintain a good grade. Lectures notes will not be available online to discourage skipping lectures or passively listening during classes. College policies on attendance, withdrawals and incomplete grades: These are stated in the Great Basin College Catalog, available on-line. There are no extra credits activities associated with this course. 7. If a student is absent for an exam, quiz, or lab session it is important to inform the instructor before hand if possible. Students have two days to make up the assignment. If no prior contact is made with the instructor, 10 points will be taken off of each assignment for each day after the scheduled date, unless your absence is due to illness or family emergency. Not being prepared to take an exam or quiz is not an acceptable excuse. Academic Dishonesty/Plagiarism: Each student is expected to be honest in his or her work. Plagiarism is dishonest. Plagiarism includes, but is not limited to, the use, by paraphrase or direct quotation, of the published or unpublished work of another person without full and clear acknowledgment. It also includes the unacknowledged use of materials prepared by another person or agency engaged in the selling of term papers and/or other academic materials. As per Great Basin College policy, plagiarism is defined as: “Plagiarism is presenting someone else’s word, ideas or data as one’s own. When a student submits work that includes the words, ideas, or data of others, the source of that information must be acknowledged through complete, accurate, and specific references; and if verbatim statements are included, through quotation marks as well. In academically honest writing or speaking, the students will acknowledge the source whenever: Another person’s actual words are quoted Another person’s idea, opinion or theory is used, even if it is completely paraphrased in the student’s own words Facts, statistics, or other illustrative materials are borrowed, unless the information is common knowledge.” Cheating: Each student is expected to be honest in his or her work. Cheating is dishonest. The term “cheating” includes but is not limited to: (1) use of any unauthorized assistance in taking quizzes, tests, or examinations; (2) dependence upon the aid of sources beyond those authorized by the instructor in writing papers, preparing reports, solving problems, or carrying out other assignments; or (3) the acquisition, without permission, of tests or other academic material belonging to a member of the College faculty or staff. Any interaction between students in a testing situation may be interpreted as cheating. Academic honesty is twofold on the part of the student; first, not to cheat, and second, not to enable others to cheat. 4 Time spent on homework: Each student is expected to work an average of 4 hours outside of the classroom, mostly for reading assignments and writing of the report. Responsibilities: Students are responsible for completing all of the assigned readings and assignments prior to the time the class meet to cover that material. I expect everyone to contribute to the course by asking questions, participating in discussions, and filing out end-of-class feedback forms. It is my responsibility in this class to evaluate student work fairly and to give feedback on assignments in a timely fashion. I am here to help you not only learn the material covered in class, but also develop skills that will assist you in learning throughout your academic and professional careers. To that end, please feel free to ask me questions inside or outside of class if there is something you don’t understand – one my primary objectives is provide a supportive community for learning. Most important, please be assured that I want students to learn and to receive the good grades they deserve. So please make an appointment with me should you have undue difficulty with your work in the course. To facilitate learning, please be respectful of your classmates by adhering to the list below: · Be prepared for class (at the very least, skim reading before class). · Do not be late to class (classes will start and end on time). · Avoid conversations with others during class (unless it is related to the course material). · Limit food/beverages to those that can be consumed quietly (i.e. don’t bring a bag chips unless you want me to eat them). · Turn off pagers and cell phones (unless you want me to have to chat with your caller). 5 Outline of Lecture and Lab schedule: 1) Lecture, Reading Assignments, and Exam Dates Week Chapter Topic 1 1 Introduction, Biology: Exploring Life 2 2 Chemistry 3 3 Organic Molecules Exam I Monday, Sept 17 4 4 Cells 5 5 Working Cell 6 6 Respiration 7 7 Photosynthesis Exam II Monday, Oct 15 8 8 Cellular Reproduction 9 9 Mendelian Genetics & Chromosomes 10 10 DNA 11 11 Control of Gene Expression Exam III Monday, Nov 12 12 13 14 15 12 13 14 15 DNA technology Evolution Origin of Species Evolutionary History Final Exam: Wednesday, Dec 12 Reading assignments and exam dates are tentative. The instructor reserves the right to alter the class schedule when necessary, but will provide at least a one week notice of any changes regarding assignments, exams, and quizzes. It is important for all students to be aware that this is a college course, for which each person has invested the same amount of funds and class time. Any rude or disruptive behavior that interferes with the learning environment of others will be dealt with by the instructor according to college policies. Plagiarism and cheating are also serious activities that will result in the loss of all points for that particular assignment. Under college policies, plagiarism and cheating also have to be reported to the college administration which will keep such records on file. 6 2) Lab Schedule Week of: Sept 3 Sept 10 Sept 17 Sept 24 Oct 1 Oct 8 Exercise Handout Ex # 3 Ex # 6 Ex # 7 Ex # 8 Ex # 9 Oct 15 Lab Practical I Oct 22 Oct 29 Nov 5 Nov 12 Nov 19 Nov 26 Ex # 10 Ex # 11 Ex # 12 Ex # 13 Ex # 14 Ex # 16 Dec 3 Lab Practical II Quiz? no yes yes yes yes yes no yes yes yes yes yes Topic Scientific Method Microscopy Cells Diffusion and Osmosis Enzymes Photosynthesis Respiration Mitosis Meiosis Genetics DNA Evolution Always read the lab exercise ahead of time. Knowing the procedure allows the exercise to go more smoothly and quickly. In lab it is expected that students will work in pairs, but write up their own lab reports and answer the questions individually on quizzes. Quizzes: Most labs will begin with a brief 10 point quiz. Quizzes will consist of one or two questions on the current weeks exercise, with the balance of the 10 points on the previous weeks exercise. Quizzes must be taken during the given lab period, there will be no ‘make up quiz’ for missed labs! 7 Lab Report: Exercise 8, Enzymes, will be written up as a report. The report must be typed, double spaced. The report Must follow the following outline: Introduction Give the background to the topic. Why is it important? Briefly tell what you are going to do in the experiment. Procedures Explain what organisms, materials and methods were used in the experiments. How did you do it? Results Present the results. Point out key or unexpected results. Conclusion What was the significance of your results? Explain the importance of the experiment, and whether or not your outcome was consistent or inconsistent with what was expected. Note: Exercise 8 consists of several sections, each section does not require a separate section of Procedures, Results etc. Rather, they should be combined into one report. Tables, graphs, etc. may be helpful. Do not remove pages from your manual. Grading criteria for the report are identical to those used by the English department: 1. Focuses and develops ideas effectively, showing creativity and insight. 2. Organizes ideas in a purposeful and logical manner, moving the reader (listener) smoothly through the text (subject). 3. Uses sentence structure and word choice effectively with a sense of control. 4. Commits few, if any, errors in grammar/usage and mechanics. 8