CHEMISTRY CHEM 331L - ORGANIC CHEMISTRY LABORATORY I
Fall 2013 (1hr.)
CHEM 331L: Laboratory safety, synthesis, separation, and purification of carbon compounds. Three laboratory
hours per week.
Sec. 001: Tuesday., 1:40 - 4:20 p.m.; Room 320 SBDG (Dr. Choony)
Sec. 002: Wednesday., 2:30 - 5:20 p.m.; Room 320 SBDG (Dr. Choony)
Sec. 003: Thursday., 1:40 - 4:20 p.m.; Room 320 SBDG (Mr. Bill or Miss Fiona)
Sec. 004: Thursday., 9:25 - 12:05 noon: ; Room 320 SBDG (Mr. Bill or Miss Fiona)
INSTRUCTOR: Dr. N. Choony, Office: 303 SBDG
Telephone: 641-3409;
Email: nandeoc@usca.edu
OFFICE HOURS:
Mondays-Fridays 11:00 a.m -12:00 noon or any other time by appointment. Messages may be left on my
answering machine, on the notepad on my office door, or with the department secretary in 201 SBDG.
REQUIRED MATERIALS:
Lab Manual, top bound quadrille notebooks with carbonless duplicate pages, and "Sharpie Marker" are required
and available in the bookstore. You may use your own safety goggles or those provided in the lab.
CO-REQUISITE:
For all USCA degree seeking students, CHEM 331L is a co requisite to CHEM 331. All regular degree
seeking USCA students must be enrolled in the lecture and laboratory simultaneously. The only
exception is someone who is repeating the lecture and has previously received credit for the laboratory.
Although the laboratory is not required for engineering students planning to transfer to USC Columbia,
it is strongly recommended. For any other exceptions, a student must petition the Scholastic Standings
and Petitions Committee.
COURSE OBJECTIVES:
This course provides an introduction to the principles and practice in the organic chemistry laboratory
including:
Purification, separation, and identification of solid and liquid organic compounds, the illustration of
various reaction types, and the application of these techniques and methods to the synthesis of a variety
of compounds. Laboratory safety is emphasized.
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EDUCATIONAL OUTCOMES:
At the completion of the course, a student should be proficient with all the basic laboratory techniques
covered in the course and should be able to use them in the synthesis and characterization of organic
compounds.
ATTENDANCE:
Attendance in lab is required. If a lab is missed due to an excused absence for an emergency or a
severe illness, the lab must be made up as soon as the student is able, preferably the same week the lab
is scheduled. The student’s notebook and product will be graded according to the grading policies stated
below. If a lab is missed due to an unexcused absence, the lab still must be made up, preferably
during the same week that the lab is scheduled. However, under these circumstances, the student will
receive a penalty for the notebook and product grades. When the missed lab covers a technique that will
be used in a subsequent experiment, the student with either an excused or unexcused absence will not be
allowed in the lab to conduct this new experiment until the missed lab is made up. If a student has not
received the necessary training in a technique, his/her presence in that subsequent lab constitutes an
unacceptable safety hazard to him/herself and to others in the lab. If you know in advance that you will
miss a lab, please make arrangements with the instructor in advance. Scheduling will be determined by
mutual agreement of instructor and the student. If the student must miss a lab for any reason, the
instructor should be notified no later than the day the lab is scheduled prior to the beginning of the lab
period. A message on the answering machine is sufficient.
GRADING:
Lab notebooks
Pre-Lab Preparation
Products
Lab quizzes
Laboratory Report
Experiment 11
Lab Final
110, 11% (11 expts @ 10 pts.)
220, 22% (11 expts @ 20 pts.)
50, 5% (5 products @ 10 pts.)
120, 12% (12 quizzes @ 10 pts.)
100, 10%
100, 10%
300, 30%
1000
LABORATORY NOTEBOOKS:
Notebooks will be spot- checked at the beginning and end of class for complete pre-lab preparation and
in class write-ups. You are not dismissed from the lab until you have completed writing the procedure
for the day's experiment. During the first few weeks of lab, the instructor will scan each student’s lab
notebook at the end of the day to critique the writing style, until the students have become accustomed to
writing it as the third person, passive voice. Penalties will be assessed for incomplete notebooks when
they are checked. Notebooks are graded on a 10 point scale and pre-labs are graded on a 20 point scale
for each experiment respectively.
The duplicates of the lab write up will be collected weekly at the beginning of the next lab period (with
the exception of Experiment 1, which will be collected with Experiment 2).
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Products from the experiments are to be turned in for grading as the work on each experiment is
completed, no later than the next lab period. Product grades are based on a 10 point scale. The product
grade criteria depend upon the experiment. In those cases where a product is actually turned in, the
grade will be based on yield and purity compared to typical results for that compound. Students having
yields and other data within the normal range will receive 10 points. Mislabeled vials, low yields,
incorrect calculations, etc. will result in lower product grades. They are to be turned in on the designated
date in lecture.
You may NOT repeat a lab just to improve your results. If a serious error is made at the beginning of the
experiment, you may start over. However, if a problem occurs at the end of the experiment such as spill
or other loss of product, a product grade equivalent to a "C" will be assigned. You must thoroughly
document the problem in your notebook.
There will be a 10 point lab quiz every week. The first lab quiz will cover lab safety and will be given on
Sept. 3, 4, 5. All quizzes will be given at the beginning of the Pre-Lab. If you are late, you miss the
quiz! No make-ups! Each quiz will be on the previous week’s experiment.
LABORATORY REPORT:
A formal laboratory report will be due on Tuesday, Nov. 29 for all sections on Experiment 10, Oxidation
Reaction. The format and details about how to write a Formal Laboratory Report are described in the
Lab Manual.
LAB FINAL:
A lab final exam will be given during exam week at the same time for all sections TBD. The lab final
will be comprehensive, stressing the interrelationship of the experiments conducted during the term.
Both theory and techniques will be covered. The exam will require approximately 1.5 hours. The
location will be announced. Alternate arrangements will be made for students who have a conflict with
this time.
DISABLED STUDENT ACCOMMODATION:
If you have a physical, psychological, and/or learning disability which might affect your performance in this
class, please contact the Office of Disability Services, 126A B&E, (803) 641-3609, as soon as possible. The
Disability Services Office will determine appropriate accommodations based on documentation.
In the event that the university cancels classes because of inclement weather or a campus emergency on
the day that an exam or assignment is scheduled, the exam or assignment will automatically be rescheduled to
the next period. Laboratory adjustments will be made as needed. If you should choose to withdraw from the
course before the withdrawal deadline of October 18, please notify the instructor to check out of the laboratory.
You are responsible for any glassware or equipment breakage. A stop will be placed on the next semester's
registration for any laboratory breakage fees owed. You will be charged a breakage fee up to a limit of $20 per
item.
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*** DUE TO THE POTENTIAL RISKS ASSOCIATED WITH WORK IN AN ORGANIC CHEMISTRY
LABORATORY, THE INSTRUCTOR RESERVES THE RIGHT TO DISMISS ANYONE WHO VIOLATES
THE SAFETY REGULATIONS. UNDER SUCH CIRCUMSTANCES, A GRADE OF ZERO WILL BE
GIVEN FOR WORK THAT DAY AND MAKE UP WORK WILL NOT BE PERMITTED.
CHEM 331L FALL 2012 LABORATORY SCHEDULE
DATE
EXPT # EXPERIMENT
LAB QUIZ
Aug.27,28,29
Check-in/ Orientation/ Safety
Sept. 3,4 ,5
1
Recrystallization
Safety
Sept.10,11,12 2
Melting Points
Recrystallization
Sept.17,18,19 3A
Thin Layer Chromatography
Melting Points
Sept.24,25,26 3B, 4A Simple
Distillation
and
Gas TLC
Chromatography
Oct. 1,2,3
4B
Fractional Distillation and Gas Simple
Chromatography
Distillation
Oct. 8,9,10
5
Extraction
Fractional
Distillation
Oct.15,16,17
NO LABS, mid-term holiday
Oct. 22,23,24 6
Resolution of a Racemic Mixture
Extraction
Oct.29,30,31 7
SN2 Reaction, To Prepare 1- Resolution
Bromobutane
Nov. 5,6,7
9
Elimination Reaction -- Methyl SN2
Cyclohexenes
Nov.12,13,14 10
Oxidation Reaction -- 2-Octanone
E1
Nov.19,20,21 11
Reduction Reaction -- Benzhydrol
Oxidation
Nov.26,27,28
No labs, Thanksgiving
Dec. 3,4,5
Lab Report Due on Oxidation Reduction
Reaction, IR Spectroscopy/ Check-out
Dec. TBD
Lab Final (All sections) at TBD
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