Course Syllabus
Fall 2013
Medical Physiology II
BIO 413/5413
Instructors: Jerry Reagan, Ph.D., Associate Professor & Elizabeth Brandon, Ph.D., Assistant Professor
Offices:
203 Hederman Science Building
211 Hederman Science Building
(601)-925-3579
(601)-925-7764
reagan@mc.edu
ebrandon@mc.edu
Site to download course materials: http://moodle.mc.edu
Credit: 5 hours
STUDENTS ARE RESPONSIBLE FOR CHECKING THEIR MC EMAIL & MOODLE
Course prerequisites: BIO 111, BIO 112, BIO 305, CHE 131, CHE 142
Class times: M, W, F 10:00 – 10:50 am in Medical Science 202
T in Hederman 100
Rationale for the course
Physiology is typically taken during the first year of medical or dental school. This course covers the
following topics which are found in a medical school level physiology class: endocrinology,
gastrointestinal physiology, metabolism and liver physiology, and hematology. This course is excellent
preparation for any healthcare related graduate program.
Course description: This course is designed to provide students with detailed instruction in the
physiology of the endocrine, gastrointestinal, and hematological systems.
Course objectives and student outcomes:
1. Students will be able to describe all hormones by their functions, their means of regulation, and the
pathologies associated with their excess or deficiency.
2. Students will be able to describe the movement of food/chyme and waste through the digestive
system.
3. Students will define the functions of all digestive hormones and enzymes and describe their means of
regulation.
4. Students will be able to describe the autonomic and somatic nervous system control of the
gastrointestinal system (the central, peripheral, and enteric nervous systems).
5. Students will be able to describe the mechanisms by which nutrients are digested, absorbed, stored,
assimilated, and used by the body.
6. Students will be able to describe energy homeostasis in the human body.
7. Students will be able to describe the integration of neural, hormonal, and local control of gut
functions.
8. Students will be able to describe diseases that result from aberrant nutrient intake/absorption, excess
or deficiency of gut hormones, enzymes, and peptides, and pathology due to loss of gut innervation.
9. Students will be able to describe the physiology of reproduction in males and females.
10. Students will be able to describe the physiology of pregnancy and lactation.
11. Students will be able to describe the different functions of blood cells.
12. Students will be able to describe the production and maturation of blood cells.
13. Students will be able to describe the functions of the innate and adaptive immune systems and
describe the primary and secondary lymphoid organs.
14. Students will be able to describe HLA matching in tissue transplantation and the pathologies of organ
rejection.
Course Syllabus
Fall 2013
15. Students will be able to describe the mechanisms by which blood clots form and are cleared and
clotting disorders (means of identifying and ways to distinguish one blood disorder from another).
Methods of instruction: The course will consist of five hours of lecture per week. Because this is an
upper level undergraduate/graduate course, basic concepts will not be reviewed. Students are responsible
for bringing themselves up to speed on topics such as intracellular signaling, the secretory pathway, and
basic anatomy (e.g. major brain areas such as the hypothalamus). PowerPoint presentations, overheads,
notes on the dry-erase board, oral instructions/examples, videos, and podcasts are all methods that will be
used to convey course material.
Instructional materials:
Textbook: Guyton and Hall. Textbook of Medical Physiology, 12th edition. Elsevier, Inc. ISBN13: 978-0-7216-0240-0. ISBN-10: 0-7216-0240-1
Lecture notes will be posted online on Moodle.
*Recommended: Guyton Physiology Review, Elsevier, Inc. ISBN 978-1-4160-5452-8.
Human Physiology, Lauralee Sherwood, Thompson. ISBN 0-534-39501-5
Required Practices: reading, memorization, diagramming, writing out-of-class assignments, computer
use, and working clinical practice problems out of class.
NOTES: A tuition refund cannot be made on dropped classes after the first week of classes. The last day
to withdraw from class with a W is Friday October 25, 2013.
Refund schedule for withdrawal:
1st Week.............100%
2nd Week............. 75%
3rd Week............. 50%
4th Week............. 25%
5th Week............. 0%
Important college/class dates:
Monday September, 2013: Labor Day. No class.
Tuesday September 3, 2012: Last day to drop the class with 100% tuition refund.
Monday-Tuesday October 7-8, 2013: Fall Break. No class.
Last day to drop a class is October 25, 2013 (zero tuition refund)
Wednesday – Sunday November 27- December 1: Thanksgiving holidays
All classes meet Monday November 25
All day classes meet Tuesday November 26
Night classes do NOT meet Tuesday November 26
Attendance: Your attendance in lectures is welcomed and expected. I will follow the University
attendance policy as described in the school catalog, which can be found in The MC Undergraduate
Catalog, p.56 – 57. (http://www.mc.edu/resources/publications/catalogs.php).
Please note that your grade can be reduced as a result of excessive absences. If you miss >25% of the
classes (12 classes), you will be given an F automatically. Your grade may be lowered if you have
excessive absences.
Absence from class: It is the student’s responsibility to make-up missed assignments. There will be no
make-up quizzes. Tests missed for any reason will be made up on Monday Dec. 9 at 6:00 PM.
Course Syllabus
Fall 2013
Academic integrity: You are members of an institution that is dedicated to scholarship and spiritual
growth. This institution is part of the larger academic community, the foundation of which is based on
personal honesty. The success of this community depends on the commitment of both students and
faculty to this principle and therefore cheating and plagiarism cannot and will not be tolerated. More
importantly, Mississippi College is dedicated to empowering its students to develop the skills necessary
for “making responsible, moral choices,” and thus, the University will accept nothing less than scrupulous
honesty from its students. We will follow the University policy on Academic Honesty (Policy 2.19),
which can be found in the student handbook, The Tomahawk, pp. 41 – 43.
http://www.mc.edu/publications/handbook/academic.pdf
Cell phones are not allowed out in the classroom after class begins. They are to be kept in your book bag,
purse or pocket. They are not allowed on the desk or in your lap. Before class begins, turn cell phone
ringers OFF.
Audio recording of lectures is permitted. Video recording is NOT permitted at any time. Taking photos
with cell phones or other devices is also NOT permitted.
Recording of any type (video, audio or photos) during the review of quizzes and exams is NOT permitted.
Testing procedures:
-Touching a cell phone after an exam is passed out will result in loss of 20 points on the exam.
-Failure to turn off recording devices during such times is considered cheating and will result in
an F on the exam and possible disciplinary procedures for cheating.
-Touching a cell phone or other electronic devices other than the calculator that was provided to
you is NOT permitted and will result in an F on the exam.
Procedures for reviewing tests:
-Students will be given one opportunity to review an exam they previously completed. In one of
the lectures (the date will be announced), students will be given the answer sheet only.
-The questions will be reviewed on the overhead projector or in a PowerPoint presentation.
-During the review, students are not allowed to write any information. They are also not allowed
to record any part of the exam (including photos, audio recording and video recording and any
other recording of info). Cell phones and other electronic devices must be turned off and put
away. Students must return the answer sheet following the review. Failure to return the answer
sheet or writing or recording information will result in a zero on the exam and students may be
reported as having cheated on the exam.
-Violation of this will be considered a violation of our honor code and will go onto your
permanent record. This may result in expulsion from the course or program and will be reported
to any graduate or professional school to which you apply.
Tutoring: Available for students upon request through your instructor. The tutors for this class are
Michael Peterson, mpeterson@mc.edu and Megan Lomax, lomax@mc.edu. They will set up Facebook
pages for the class and publish their study section times. Tutoring is free and it is strongly encouraged for
students to attend study sessions.
Special Accommodations for Students: In order for a student to receive disability accommodations under
Section 504 of the Americans with Disabilities Act, he or she must schedule an individual meeting with
the Director of Student Counseling Services immediately upon recognition of their disability (if their
disability is known, they must come in before the semester begins or make an appointment immediately
upon receipt of their syllabi for the new semester). The student must bring with them written
documentation from a medical physician and/or licensed clinician that verifies their disability. If the
Course Syllabus
Fall 2013
student has received prior accommodations, they must bring written documentation of those
accommodations (example Individualized Education Plan from the school system). Documentation must
be current (within 3 years). The student must meet with SCS face-to face and also attend two (2)
additional follow up meetings (one mid semester before or after midterm examinations and the last one at
the end of the semester). Please note that the student may also schedule additional meetings as needed for
support through SCS as they work with their professor throughout the semester. Note: Students must
come in each semester to complete their Individualized Accommodation Plan (example: MC student
completes fall semester IAP plan and even if student is a continuing student for the spring semester they
must come in again to complete their spring semester IAP plan).
Student Counseling Services is located in Alumni Hall Room #4 or they may be contacted via
email at : mbryant@mc.edu or rward@mc.edu or by phone at 601-925-7791.
Student evaluation:
1. Every Tuesday at 1:30 pm, a quiz will be given. Questions can come from lecture notes, the
textbooks, or class discussions. Quizzes are not comprehensive. Quizzes missed for any reason result in
a grade of zero for that quiz. Your top ten quiz scores will be counted. The quiz grade counts for 10%
of your final grade.
2. Graduate Students will be given a 2-3 scholarly review papers to learn. Undergraduates will be given 1
scholarly review paper to learn. Questions on those papers will be given with the third test and will
constitute 10% of your final course grade. Questions may be short answer, discussion, multiple choice, or
a combination of the three. The grade on these questions counts for 10% of your final grade.
3. Tests are comprehensive. Weighted test scale:
Test 1: 7.5%
Test 2: 13.5%
Test 3: 22.5%
Final exam: 36.5% Monday, December 16 8:00 a.m. - 11:00 a.m. in Medical Sciences 202.
4. The National Board of Medical Examiner’s Neuroscience Board Exam will be given December 19,
8:00AM. Only students who are taking 2 Shelf exams can take one of the exams at 1 PM that same day.
If you score 500 or greater on the Physiology Board Exam, your grade will be raised by one letter grade.
Example, C to B; C+ to B+; B+ to A.
Undergraduate Grading scale: 85-100% = A, 75.0-84.9% = B, 65.0-74.4% = C, 60-64.9% = D, 59.9% or
less = F
Graduate Grading scale: 85-100% = A, 80.0-84.9% = B+, 75.0-79.9% = B, 70.0-74.9% = C+, 65-69.9%
= C, 60-64.9% = D, less than 60% = F
Course Schedule & Topics
Gastrointestinal Physiology
Ch. 62
Ch. 63
Ch. 64
Ch. 65
Ch. 66
Test 1
General Principles of Gastrointestinal Function—Motility,
Nervous Control & Blood Circulation
Propulsion & Mixing of Food in the Alimentary Tract
Secretory Functions of the Alimentary Tract
Digestion & Absorption in the Gastrointestinal Tract
Physiology of GI Disorders
Tuesday September 24
Course Syllabus
Fall 2013
Metabolism
Ch. 71
Ch. 70
Ch. 78
Ch. 67
Ch. 68
Ch. 69
Test 2
Dietary Balances, Regulation of Feeding, Obesity & Starvation,
Vitamins & Minerals
The Liver as an Organ
Insulin, Glucagon, & Diabetes Mellitus
Metabolism of Carbohydrates and Formation of ATP
Lipid Metabolism
Protein Metabolism
Tuesday October 22
***************LAST DAY TO DROP IS FRIDAY OCTOBER 25*****************
Endocrinology
Ch. 74
Ch. 75
Ch. 76
Ch. 77
Ch. 79
Ch. 80
Ch. 81
Ch. 82
Test 3
Introduction to Endocrinology
Pituitary Hormones & Their Control by the Hypothalamus
Thyroid Metabolic Hormones
Adrenocortical Hormones
Parathyroid Hormone, Calcitonin, Calcium & Phosphate
Metabolism, Vitamin D, Bone, & Teeth
Reproductive & Hormonal Functions of the Male
Female Physiology Before Pregnancy & the Female Hormones
Pregnancy & Lactation
Tuesday November 26
Hematology
Ch. 32
Ch. 33
Final exam:
Red Blood Cells, Anemia, & Polycythemia
Resistance of the Body to Infection I: Leukocytes,
Granulocytes, the Monocyte-Macrophage System, &
Inflammation
Ch. 34
Resistance of the Body to Infection II: Immunity & Allergy
Ch. 35
Blood Types, Transfusion, Tissue & Organ Transplantation
Ch. 36
Hemostasis & Blood Coagulation
Monday, December 16 8:00 a.m. - 11:00 a.m. in Medical Sciences 202