Fine Chemical Products Your Specialist for Hazardous Reactions. DOTTIKON EXCLUSIVE SYNTHESIS AG Your Specialist for Hazardous Reactions. DOTTIKON EXCLUSIVE SYNTHESIS AG (DOTTIKON ES) is a fine chemical company, specializing in hazardous chemical reactions. At the center of our strategy is a customer-driven focus to provide our clients with exclusive custom manufacturing services as well as with fine chemical products available on catalog. We are flexible and responsive through our rapid, problem solving approach to client needs and we shape our research and development efforts in this manner. Our streamlined decision process, the ability to ramp up production quickly and the sophisticated plants and equipment operated by our highly experienced employees allow us to achieve the ambitious targets of our clients. We seek to further expand on this platform by continuously improving the quality and efficiency of the production process by close exclusive interaction with our customers to reach a long term and unique relationship. DOTTIKON ES is specialized in hazardous reactions. Our history in handling explosives in the past makes us one of the most experienced partners in the industry for conducting exothermal reactions such as nitrations, oxidations and azide chemistry, to name a few. Further core technologies are catalytic hydrogenations, alkylations and metallation reactions. Broad process development experience and technological expertise enables us to offer high-quality chemicals and intermediates, including Amines Anilines Azaindoles Benzimidazoles Benzoic acid derivatives Benzyl compounds Boron building blocks Chiral compounds Cyclohexane derivatives Cyclopropyl building blocks Indazoles Indoles N-Heterocycles (various) Nitrate esters Nitroaromatic compounds O-Heterocycles (various) Phenols and anisoles Pyridine building blocks 3 Core Competencies Catalytic Hydrogenation Heterogeneous (screenings with >400 catalysts) Homogeneous Enantioselective Hazardous Reactions Azides (NaN3, organic azides) Bromination (Br2, HBr, POBr3, PBr3, NBS) Chlorination (Cl2, HCl, SOCl2, SO2Cl2, PCl3, NaBH4, BH3) PCl5, POCl3, NCS) Hydrazine chemistry Hydride reduction (LiAlH4, NaR2AIH2, NaH, Iodination (I2, NaI, RI) Cyanation (NaCN, acetone cyanohydrine) Cyclopropanation (ethyl diazoacetate) Dehydration (P2O5) Diazotation, aromatic and aliphatic (HONO, t-BuONO) Friedl-Crafts reactions Methylation (MeI, Me2SO4) Mitsunobu reaction (DIAD) Nitroaldol reaction (RNO2) Organometallic chemistry (Grignard, RLi) Oxidation (HNO3, O2, peracids, KMnO4, DDQ) Peroxidation (peroxides, peracids) Heterocycle Synthesis Isoquinolines and quinolines Benzimidazoles Benzofuranes Indazoles and Indoles Purine analogs Triazoles and tetrazoles Low-Temperature Chemistry Metallorganic transformations Selective oxidations and hydrogenations Boronic acid synthesis Cryogenic quenching Nitration Aromatic nitration (conc. HNO3, HNO3/H2SO4, HNO3/glacial AcOH/Ac2O) Continuous nitration technology Nitrate ester formation Cross Coupling Reactions Stille Suzuki-Miyaura Heck Sonogashira Kumada Negishi Separation and Drying under cGMP Stereoisomer separation by fractionated crystallization Filtration and centrifugation on all scales Distillation (0.1–50 m3; columns up to 80 theoretical plates) 4 Drying on large scale (up to 6 m3) More than 100 Reactions on Large Scale Typical Reactions Alkoxylation Alkylation Aromatic substitution Baeyer-Villiger oxidation Beckmann rearrangement Benzidine rearrangement Boronic acid synthesis Cannizzaro reaction Carbamoylation Chiral chemistry Chlorosulfonation Claisen condensation Cross coupling Curtius rearrangement Cycloaddition Cyclocondensation Darzens synthesis Dealkylation Decarboxylation Dehalogenation Diazonium chemistry Dieckmann condensation Diels-Alder reaction Doebner-Knoevenagel condensation Hydrogenation Hydrosilylation Isomerization Ketalization Liquid-ammonia reactions Methylation Michael addition Mitsunobu reaction Nef reaction Nitration Optical resolution ortho-Directed metallation Oxidation Oxime formation Phase-transfer reactions Pictet-Spengler reaction Pinner reaction Reduction Reductive coupling Reductive cyclization Robinson annulation Esterification Ether formation Finkelstein reaction Indole synthesis Formylation Gabriel synthesis Halide exchange Halogenation Hemetsberger reaction Hofmann rearrangement Hydrolysis ... Metal complexation Wohl-Ziegler reactions Mesylation Epoxidation Wittig reaction Mannich reaction Wacker oxidation Lithiation Enantioselective reactions Vilsmeier-Haack reaction Rosenmund reduction Sandmeyer reaction Schiff-base reduction Schotten-Baumann reaction Skraup synthesis Solid acid catalysis Strecker synthesis Substitution reactions Sulfonation Sulfoxidation Tosylation Transesterification Ullmann coupling 5 Content Product Groups Products 8–9 10–45 Index, Chemical Formula 46 Index, Registry Number 47 Index, Parent Name 48–52 Notes 53–54 Contact 55 The copyright of any content (text, illustration and pictures) in this catalogue is owned by DOTTIKON ES HOLDING AG. Unauthorized reproduction of any content is prohibited by Federal law and subject to criminal prosecution. 7 Product Groups Structure 8 Product Group Name Page Amines piperidines, piperazines, aliphatic amines 10−11 Anilines 12−14 Azaindoles 15 Benzimidazoles 16 Benzoic Acid Derivatives 17−20 Benzyl Compounds 21−22 Boron Building Blocks 23 Chiral Compounds 24 Cyclohexane Derivatives cyclohexanones, cyclohexane-based carboxylic acids and alcohols 25−27 Cyclopropyl Building Blocks 28 Structure Product Group Name Page Indazoles 29 Indoles 30−33 N-Heterocycles (various) benzotriazoles, imidazoles, isoquinolines, quinolines, quinoxalines, tetrazoles 34−35 Nitrate Esters 36 Nitroaromatic Compounds 37−38 O-Heterocycles (various) benzodioxanes, benzodioxoles, isosorbide derivatives 39 Phenols and Anisoles 40−41 Pyridine Building Blocks 42−43 Various Compounds 44−45 9 Product Amines (1/2) Structure Product Name CAS cis-1-Amino-2,6-dimethylpiperidine 61147-58-8 (Z)-N-Amino-2,6-dimethylpiperidine 6-Amino-1-hexanol 4048-33-3 Aminomalonic acid diethyl ester hydrochloride 13433-00-6 Diethyl aminomalonate hydrochloride 2-(Aminomethyl)-1-ethylpyrrolidine 26116-12-1 N-Ethyl-2-aminomethylpyrrolidine 2-(Aminomethyl)piperidine 22990-77-8 2-Piperidinemethylamine 1-Aminopiperidine 2213-43-6 1-Piperidinamine 1-Benzylpiperazine 2759-28-6 1-Benzyl-4-piperidinamine 50541-93-0 4-Amino-1-benzylpiperidine 10 Product Amines (2/2) Structure Product Name CAS 4-Benzylpiperidine 31252-42-3 1,4-Diazabicyclo[3.2.2]nonane dihydrochloride 150208-70-1 2,3-Dimethylcyclohexylamine 42195-92-6 2,3-Dimethylcyclohexanamine cis-2,6-Dimethylpiperidine 766-17-6 3,5-Dimethylpiperidine 35794-11-7 3,5-Lupetidine (cis:trans ≈ 83:17) 1-Methyl-3-phenylpropylamine 22374-89-6 4-Phenyl-2-butylamine 1-(Tetrahydro-2-furoyl)piperazine 63074-07-7 THF-Piperazine DL-m-Tyrosine 775-06-4 3-(3-Hydroxyphenyl)-DL-alanine 11 Product Anilines (1/3) Structure Product Name CAS 4-Aminoacetophenone 99-92-3 1-(4-Aminophenyl)ethanone 4-Acetylaniline 4-Amino-N-ethyl-N-isopropylaniline hydrochloride 91215-79-1 N-Ethyl-N-isopropyl-para-phenylenediamine hydrochloride 3-Amino-4-methoxybenzaldehyde 351003-10-6 2-Amino-6-methylbenzonitrile 56043-01-7 N-(3-Amino-2-methylphenyl)acetamide 65999-76-0 3-Amino-2-methylacetanilide 4-sec-Butylaniline 30273-11-1 1,3-Diamino-4,6-diisopropylbenzene 3102-71-4 4,6-Bis-(1-methylethyl)-1,3-benzenediamine 2,4-Diamino-1,3,5-trimethylbenzene 2,4-Diaminomesitylene 2,4,6-Trimethyl-meta-phenylenediamine 12 3102-70-3 Product Anilines (2/3) Structure Product Name CAS 3,4-Dimethoxyaniline 6315-89-5 4-Aminocatechol dimethyl ether Dodecylaniline 68411-48-3 (Isomeric mixture) 2-Ethylaniline 578-54-1 4-Ethylaniline 589-16-2 4-Methoxy-2-methylaniline 102-50-1 2-Methyl-para-anisidine 4-Methoxy-3-nitroaniline 577-72-0 3-Nitro-para-anisidine 3-Methyl-1,2-benzenediamine 2687-25-4 2,3-Diaminotoluene (30% or 50% in toluene) 2-Methyl-3-nitroaniline 603-83-8 3-Nitro-ortho-toluidine 13 Product Anilines (3/3) Structure Product Name CAS 2-Methyl-6-nitroaniline 570-24-1 6-Nitro-ortho-toluidine 2,3,5,6-Tetramethyl-1,4-benzenediamine 3102-87-2 3,6-Diaminodurene 2,3,5,6-Tetramethyl-para-phenylenediamine 2,4,6-Trimethylaniline Mesidine 14 88-05-1 Product Azaindoles Structure Product Name CAS 4-Azaindole-2-carboxylic acid methyl ester 394223-19-9 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester 4-Chloro-5-azaindole-2-carboxylic acid methyl ester 688357-19-9 4-Chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester 4-Chloro-7-azaindole-2-carboxylic acid methyl ester 871583-23-2 4-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester 7-Bromopyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester – 6-Chloropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester 1222709-26-3 Pyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester 151831-21-9 Pyrazolo[1,5-a]quinoline-2-carboxylic acid methyl ester – 15 Product Benzimidazoles Structure Product Name CAS 2-Amino-1H-benzimidazole 934-32-7 2-Aminobenzimidazole 1H-Benzo[d]imidazol-2-amine 5-Amino-1,3-dihydro-2H-benzimidazol-2-one 95-23-8 5-Amino-1,3-dihydrobenzimidazol-2-one 5-Amino-2-benzimidazolinone 5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one 67014-36-2 5-Amino-6-methyl-1,3-dihydrobenzimidazol-2-one 5-Amino-6-methyl-2-benzimidazolinone 2-Anilino-1H-benzimidazole 21578-58-5 2-Anilinobenzimidazole 2-Phenylamino-1H-benzimidazole 5,6-Dichloro-1H-benzimidazole 6478-73-5 5,6-Dichlorobenzimidazole 5,6-Dichloro-1H-benzo[d]imidazole 5,6-Dimethyl-1H-benzimidazole 582-60-5 5,6-Dimethylbenzimidazole 5,6-Dimethyl-1H-benzo[d]imidazole 2-Methyl-5-nitro-1H-benzimidazole 2-Methyl-5-nitrobenzimidazole 2-Methyl-5-nitro-1H-benzo[d]imidazole 16 1792-40-1 Product Benzoic Acid Derivatives (1/4) Structure Product Name CAS 2-Amino-4-chlorobenzoic acid 89-77-0 4-Chloroanthranilic acid 2-Amino-4-chlorobenzoic acid methyl ester 5900-58-3 4-Chloroanthranilic acid methyl ester 4-Amino-5-chloro-2-methoxybenzoic acid methyl ester 108282-38-8 2-Amino-4,5-dimethoxybenzoic acid methyl ester 26759-46-6 4,5-Dimethoxyanthranilic acid methyl ester 6-Aminoveratric acid methyl ester 2-Amino-5-hydroxybenzoic acid 394-31-0 5-Hydroxyanthranilic acid 2-Amino-5-methoxybenzoic acid 6705-03-9 6-Amino-meta-anthranilic acid 2-Amino-5-methylbenzoic acid 2941-78-8 6-Amino-meta-toluic acid 2-Amino-6-methylbenzoic acid 4389-50-8 6-Amino-ortho-toluic acid 17 Product Benzoic Acid Derivatives (2/4) Structure Product Name CAS 3-Amino-2-methylbenzoic acid 52130-17-3 3-Amino-ortho-toluic acid 3-Amino-2-methylbenzoic acid methyl ester 18583-89-6 3-Amino-ortho-toluic acid methyl ester 3-Amino-4-methylbenzoic acid 2458-12-0 3-Amino-para-toluic acid 3-Amino-4-methylbenzoic acid methyl ester 18595-18-1 3-Amino-para-toluic acid methyl ester 4-Amino-3-methylbenzoic acid methyl ester 18595-14-7 4-Amino-meta-toluic acid methyl ester 18 2-Chloro-5-iodobenzoic acid 19094-56-5 2-Chloro-5-iodobenzoic acid methyl ester 620621-48-9 2-Chloro-5-nitrobenzoic acid 2516-96-3 Product Benzoic Acid Derivatives (3/4) Structure Product Name CAS 4-Chloro-2-nitrobenzoic acid methyl ester 42087-80-9 3,4-Dimethoxybenzoic acid 93-07-2 Veratric acid 3,5-Dinitro-4-methylbenzoic acid 16533-71-4 3,5-Dinitro-para-toluic acid 3-Hydroxy-4-nitrobenzoic acid 619-14-7 3-Methoxy-2-methylbenzoic acid 55289-06-0 3-Methoxy-ortho-toluic acid 2-Methyl-3-nitrobenzoic acid 1975-50-4 3-Nitro-ortho-toluic acid 2-Methyl-3-nitrobenzoic acid methyl ester 59382-59-1 3-Nitro-ortho-toluic acid methyl ester 2-Methyl-6-nitrobenzoic acid 13506-76-8 6-Nitro-ortho-toluic acid 19 Product Benzoic Acid Derivatives (4/4) Structure Product Name CAS 3-Methyl-4-nitrobenzoic acid methyl ester 24078-21-5 4-Nitro-meta-toluic acid methyl ester 4-Methyl-3-nitrobenzoic acid 96-98-0 3-Nitro-para-toluic acid 4-Methyl-3-nitrobenzoic acid methyl ester 7356-11-8 3-Nitro-para-toluic acid methyl ester 20 5-Nitroisophthalic acid dimethyl ester 13290-96-5 5-Nitroisophthalic acid monomethyl ester 1955-46-0 Product Benzyl Compounds (1/2) Structure Product Name CAS 3-(Aminomethyl)aniline 4403-70-7 3-Aminobenzylamine 4-(Aminomethyl)benzoic acid 56-91-7 3-(Aminomethyl)nitrobenzene 7409-18-9 3-Nitrobenzylamine 3-(Aminomethyl)nitrobenzene hydrochloride 26177-43-5 3-Nitrobenzylamine hydrochloride Benzylhydrazine hydrochloride 1073-62-7 2-(Bromomethyl)benzonitrile 22115-41-9 2-Cyanobenzyl bromide 3-(Bromomethyl)benzonitrile 28188-41-2 3-Cyanobenzyl bromide 1-(Bromomethyl)-3-nitrobenzene 3958-57-4 3-Nitrobenzyl bromide 21 Product Benzyl Compounds (2/2) Structure Product Name CAS 3,4-Dimethoxybenzyl alcohol 93-03-8 3,4-Dimethoxybenzenemethanol Veratryl alcohol 22 Product Boron Building Blocks Structure Product Name CAS (2-Chloro-3-pyridinyl)boronic acid 381248-04-0 2-Chloro-3-pyridineboronic acid Cyclopropylboronic acid 411235-57-9 Cyclopropylboranediol 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 126689-01-8 Cyclopropylboronic acid pinacol ester 2-Fluoro-6-methoxybenzeneboronic acid 78495-63-3 2-Fluoro-6-methoxyphenylboronic acid (2-Fluoro-3-pyridinyl)boronic acid 174669-73-9 2-Fluoro-3-pyridineboronic acid 2-Furanboronic acid 13331-23-2 Potassium cyclopropyl-1-trifluoroborate 1065010-87-8 Potassium 5-methylfuran-2-trifluoroborate 1111213-54-7 Potassium 5-methylfuran-2-yltrifluoroborate 23 Product Chiral Compounds Structure Product Name CAS (+)-Diacetyl-L-tartaric acid anhydride 6283-74-5 (3R,4R)-3,4-Diacetoxytetrahydrofuran-2,5-dione Dottisol® 5306-85-4 Isosorbide dimethyl ether Dimethyl isosorbide (DMI) 1,4:3,6-Dianhydro-D-sorbitol dimethyl ether Isosorbide 652-67-5 1,4:3,6-Dianhydro-D-sorbitol (S)-4-Nitrophenylalanine 949-99-5 (S)-2-Amino-3-(4-nitrophenyl)propanoic acid (S)-4-Nitrophenylalanine methyl ester hydrochloride 17193-40-7 (S)-2-Amino-3-(4-nitrophenyl)propanoic acid methyl ester hydrochloride (R)-1-(4-Nitrophenyl)ethylamine hydrochloride 57233-86-0 (R)-(−)-α-Methyl-4-nitrobenzylamine hydrochloride (S)-1-(4-Nitrophenyl)ethylamine hydrochloride (S)-(+)-α-Methyl-4-nitrobenzylamine hydrochloride 24 132873-57-5 Product Cyclohexane Derivatives (1/3) Structure Product Name CAS (Bromomethyl)cyclohexane 2550-36-9 Cyclohexylmethyl bromide 2-sec-Butylcyclohexanone 14765-30-1 2-tert-Butylcyclohexanone 1728-46-7 4-Butylcyclohexanone 61203-82-5 4-tert-Butylcyclohexanone 98-53-3 4-Cyclohexanonecarboxylic acid ethyl ester 17159-79-4 4-Oxocyclohexanecarboxylic acid ethyl ester 1,3-Cyclohexanedicarboxylic acid dimethyl ester 62638-06-6 1,4-Cyclohexanedicarboxylic acid dimethyl ester 94-60-0 25 Product Cyclohexane Derivatives (2/3) Structure Product Name CAS 1-Cyclohexylethanol 1193-81-3 1-Cyclohexyl-1-ethanone 823-76-7 Cyclohexyl methyl ketone 2,6-Dimethylcyclohexanone 2816-57-1 4,4-Dimethylcyclohexanone 4255-62-3 4-(1,4-Dioxaspiro[4.5]dec-8-yl)cyclohexanone 56309-94-5 Bicyclohexyl-4,4'-dione monoethyleneglycol ketal Dicyclohexane-4,4'dione monoethylene ketal Ketoketal 26 4-Ethylcyclohexanone 5441-51-0 4-(4-Hydroxyphenyl)cyclohexanone 105640-07-1 2-Isopropylcyclohexanone 1004-77-9 Product Cyclohexane Derivatives (3/3) Structure Product Name CAS 2-Methylcyclohexanone 583-60-8 3-Methylcyclohexanone 591-24-2 4-Methylcyclohexanone 589-92-4 4-Pentylcyclohexanone 61203-83-6 4-Phenylcyclohexanone 4894-75-1 4-Propylcyclohexanone 40649-36-3 trans-4-(4'-Propylcyclohexyl)cyclohexanone 82832-73-3 trans-4'-Propylbi(cyclohexan)-4-one 2,2,6-Trimethylcyclohexanone 2408-37-9 27 Product Cyclopropyl Building Blocks Structure Product Name CAS Cyclopropylboronic acid 411235-57-9 Cyclopropylboranediol Cyclopropyl bromide Bromocyclopropane 4333-56-6 130561-87-4 Cyclopropyllithium 3002-94-6 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 126689-01-8 Cyclopropylboronic acid pinacol ester 28 Cyclopropylzinc bromide 126403-68-7 Potassium cyclopropyl-1-trifluoroborate 1065010-87-8 Product Indazoles Structure Product Name CAS 4-Amino-1H-indazole-1-carboxylic acid methyl ester 581812-76-2 6-Amino-1H-indazole 6967-12-0 1H-Indazol-6-amine 1H-Indazole-3-carboxylic acid 4498-67-3 1H-Indazole-4-carboxylic acid 677306-38-6 2-Methyl-2H-indazol-6-amine 50593-30-1 6-Amino-2-methyl-2H-indazole 6-Nitro-1H-indazole 7597-18-4 29 Product Indoles (1/4) Structure 30 Product Name CAS 5-(Benzyloxy)-1H-indole 1215-59-4 7-(Benzyloxy)-1H-indole 20289-27-4 5-Bromo-1H-indole-2-carboxylic acid 7254-19-5 5-Bromo-1H-indole-2-carboxylic acid ethyl ester 16732-70-0 4-Chloro-1H-indole 25235-85-2 5-Chloro-1H-indole-2-carboxylic acid 10517-21-2 5-Chloro-1H-indole-2-carboxylic acid ethyl ester 4792-67-0 6-Chloro-1H-indole 17422-33-2 Product Indoles (2/4) Structure Product Name CAS 6-Chloro-1H-indole-2-carboxylic acid 16732-75-5 6-Chloro-1H-indole-2-carboxylic acid methyl ester 98081-84-6 6-Fluoro-1H-indole 399-51-9 6-Fluoro-1H-indole-2-carboxylic acid methyl ester – 3-Formyl-1H-indole-5-carboxylic acid methyl ester 197506-83-5 1H-Indole-4-carboxylic acid methyl ester 39830-66-5 1H-Indole-5-carboxylic acid methyl ester 1011-65-0 1H-Indole-6-carboxylic acid methyl ester 50820-65-0 31 Product Indoles (3/4) Structure 32 Product Name CAS 1H-Indole-7-carboxylic acid methyl ester 93247-78-0 5-Methoxy-1H-indole 1006-94-6 5-Methoxy-1H-indole-3-carbaldehyde 10601-19-1 6-Methoxy-1H-indole 3189-13-7 6-Methoxy-1H-indole-2-carboxylic acid methyl ester 98081-83-5 4-Methyl-1H-indole 16096-32-5 6-Methyl-1H-indole 3420-02-8 1-Methyl-1H-indole-6-carboxylic acid methyl ester 1204-32-6 Product Indoles (4/4) Structure Product Name CAS 1-Methylindol-3-acetamide 150114-41-3 2-(1-Methyl-1H-indol-3-yl)acetamide 6-Nitro-1H-indole-2-carboxylic acid 10242-00-9 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid 327-20-8 33 Product N-Heterocycles (various) (1/2) Structure Product Name CAS 5-Aminoisoquinoline 1125-60-6 Isoquinolin-5-amine 5-(3-Bromophenyl)-1H-tetrazole 3440-99-1 5-(2-Hydroxyphenyl)-1H-tetrazole 51449-77-5 2-(1H-Tetrazol-5-yl)phenol 34 5-(2-Methylphenyl)-1H-tetrazole 51449-86-6 5-(3-Nitrophenyl)-1H-tetrazole 21871-44-3 4H-Furo[3,2-b]pyrrole-5-carboxylic acid methyl ester 77484-99-2 4-Methyl-1H,4H-pyrrolo[3,2-b]pyrrole-2-carboxylic acid methyl ester – 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid methyl ester 82782-85-2 Product N-Heterocycles (various) (2/2) Structure Product Name CAS 5,6-Dimethyl-1H-benzo[d][1,2,3]triazole hydrate 4184-79-6 (CAS number corresponds to the anhydrate) 5-Nitroisoquinoline 607-32-9 1,2,3,4-Tetrahydroquinoline 635-46-1 1,5-Diazabicyclo[4.3.0]non-5-ene 3001-72-7 DBN 6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione 28888-44-0 4-Nitro-1H-imidazole 3034-38-6 4-Nitroimidazole 2-Thiobarbituric acid 504-17-6 4,6-Dihydroxy-2-mercaptopyrimidine 35 Product Nitrate Esters Structure Product Name CAS Isosorbide dinitrate 87-33-2 ISDN 1,4:3,6-Dianhydro-D-sorbitol 2,5-dinitrate Isosorbide-5-mononitrate 16051-77-7 ISMN 1,4:3,6-Dianhydro-D-sorbitol 5-nitrate Pentaerythritol tetranitrate PETN Nitropenta 36 78-11-5 Product Nitroaromatic Compounds (1/2) Structure Product Name CAS 5-Bromo-2-methoxynitrobenzene 33696-00-3 4-Bromo-2-nitroanisole 2-Chloro-1,3-dimethyl-5-nitrobenzene 38560-96-2 2-Chloro-5-nitro-meta-xylene 4-Chloro-3-nitrobenzaldehyde 16588-34-4 1,5-Dichloro-2,4-dinitrobenzene 3698-83-7 1,5-Diisopropyl-2,4-dinitrobenzene 77256-78-1 1,3-Dimethyl-4-nitrobenzene 89-87-2 4-Nitro-meta-xylene Dodecylnitrobenzene 58353-63-2 (Isomeric mixture) 4-Methoxy-2-methyl-1-nitrobenzene 5367-32-8 3-Methyl-4-nitroanisole 3-Methoxy-6-nitrotoluene 37 Product Nitroaromatic Compounds (2/2) Structure Product Name CAS N-(2-Methyl-3-nitrophenyl)acetamide 56207-36-4 2-Methyl-3-nitroacetanilide 1-(4-Methyl-3-nitrophenyl)ethanone 5333-27-7 4-Methyl-3-nitroacetophenone 4-Acetyl-2-nitrotoluene 3-Nitrobenzonitrile 3-Cyanonitrobenzene 38 619-24-9 Product O-Heterocycles (various) Structure Product Name CAS 2,3-Dihydrobenzofuran 496-16-2 Coumaran 2-(2,3-Dihydro-1-benzofuran-5-yl)acetic acid 69999-16-2 Coumaranacetic acid Dottisol® 5306-85-4 Isosorbide dimethyl ether Dimethyl isosorbide (DMI) 1,4:3,6-Dianhydro-D-sorbitol dimethyl ether 4H-Furo[3,2-b]pyrrole-5-carboxylic acid methyl ester 77484-99-2 2-(Hydroxymethyl)benzofuran 55038-01-2 1-Benzofuran-2-ylmethanol Isosorbide 652-67-5 1,4:3,6-Dianhydro-D-sorbitol 39 Product Phenols and Anisoles (1/2) Structure Product Name CAS 4-Acetyl-2-nitrophenol 6322-56-1 4-Hydroxy-3-nitroacetophenone 2-Amino-5-methylphenol 2835-98-5 6-Amino-meta-cresol 2-Amino-3-nitrophenol 603-85-0 4-Amino-3-nitrophenol 610-81-1 4-Chloro-3-nitrophenol 610-78-6 2,6-Dimethyl-4-nitrophenol 2423-71-4 4-Nitro-2,6-xylenol 2-Ethylphenol 90-00-6 1-Ethynyl-3-methoxybenzene 768-70-7 3-Ethynylanisole 3-Methoxyphenylacetylene 40 Product Phenols and Anisoles (2/2) Structure Product Name CAS 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde 6635-20-7 5-Nitrovanillin 5-Hydroxy-2-nitrobenzaldehyde 42454-06-8 2-Methoxy-5-nitrophenol 636-93-1 5-Nitroguaiacol 2-Methyl-3-nitrophenol 5460-31-1 3-Nitro-ortho-cresol 2-Methyl-4-nitrophenol 99-53-6 4-Nitro-ortho-cresol 4-Methyl-3-nitrophenol 2042-14-0 3-Nitro-para-cresol 41 Product Pyridine Building Blocks (1/2) Structure Product Name CAS 6-Bromopyridine-2-carbaldehyde 34160-40-2 6-Bromo-2-formylpyridine 2-Chloro-3-iodopyridine 78607-36-0 2-Chloropyridine-3-boronic acid 381248-04-0 2-Chloropyridine-3-carbaldehyde 36404-88-3 2-Chloro-3-formylpyridine 5-Chloropyridine-2-carbaldehyde 31181-89-2 5-Chloro-2-formylpyridine 6-Chloropyridine-2-carbaldehyde 54087-03-5 6-Chloro-2-formylpyridine 2-Chloropyridine-3-carboxylic acid 2942-59-8 2-Chloronicotinic acid 2,5-Dichloro-4-iodopyridine 42 796851-03-1 Product Pyridine Building Blocks (2/2) Structure Product Name CAS 2-Fluoro-3-iodopyridine 113975-22-7 2-Fluoropyridine-3-carbaldehyde 36404-90-7 2-Fluoro-3-formylpyridine 2-Fluoropyridine-3-carboxylic acid 393-55-5 2-Fluoronicotinic acid (2-Fluoro-3-pyridinyl)boronic acid 174669-73-9 2-Fluoro-3-pyridineboronic acid 2-Iodo-6-(trifluoromethyl)pyridine 100366-74-3 43 Product Various Compounds (1/2) Structure Product Name CAS Acetamidomalonic acid diethyl ester 1068-90-2 Acetylaminomalonic acid diethyl ester Diethyl acetamidomalonate 5-Bromopentanoyl chloride 4509-90-4 5-Bromovaleryl chloride Butanoic acid 4-hydroxybutyl ester 55011-60-4 Butyl nitrite 544-16-1 tert-Butyl nitrite 540-80-7 Nitrous acid tert-butyl ester (in-situ reagent, 90% in t-BuOH) Isoamyl nitrite 110-46-3 3-Methylbutyl nitrite 1,2-Dimethylbenzene 95-47-6 ortho-Xylene 1,3-Dimethylbenzene meta-Xylene 44 108-38-3 Product Various Compounds (2/2) Structure Product Name CAS 1,4-Dimethylbenzene 106-42-3 para-Xylene Ethyl 2-isocyanoacetate 2999-46-4 2-Isocyanoacetic acid ethyl ester 1-Fluoro-4-(2-nitropropyl)benzene 29865-52-9 1-(4-Fluorophenyl)-2-nitropropane 1-Methoxy-4-(2-nitropropyl)benzene 29865-49-4 1-(4-Methoxyphenyl)-2-nitropropane 4-(2-Nitropropyl)anisole 1,3,5-Trimethylbenzene 108-67-8 Mesitylene 45 Chemical Formula Index Formula Formula Page C3H3N3O2 35 C7H6N4O 34 C3H5BF3K 23, 28 C7H7NO3 17, 41 C3H5Br 28 C7H7NO4 41 C3H5BrZn 28 C7H7N3 C3H5Li 28 C7H7N3O 16, 29 Formula C8H14O C8H14O4 C8H16O Page Formula Page C10H10O3 39 C10H13ClN2O4 24 26 C10H13NO3 45 26 24, 39 C8H16O3 44 C10H13NO4 16 C8H17N 11 C10H15N 17 11, 12 23, 28 C7H8BFO3 23 C9H6BrNO2 30 C10H16N2 C4H4N2O2S 35 C7H8N2O2 13, 14, 21 C9H6ClNO2 30, 31 C10H16O4 25 C4H5BO3 23 C7H8N2O3 13 C9H6N2O2 35 C10H18O 25 C4H9BO2 44 C7H9ClN2O2 21 C9H6N2O4 33 C11H9NO3 31 C4H9NO2 44 C7H9NO 40 C9H7BrN2O2 15 C11H10BrNO2 30 13, 21 C3H7BO2 14 C5H2Cl2IN 42 C7H10N2 C9H7ClN2O2 15 C11H10ClNO2 30 C5H3ClIN 42 C7H11ClN2 21 C9H7NO6 20 C11H11NO2 32 C5H3FIN 43 C7H12N2 35 C9H8N2 34 C11H11NO3 32 23, 42 C7H12O 27 C9H8N2O2 15 C11H12N2O 33 C5H5BF3KO 23 C7H13Br 25 C9H8O 40 C11H16N2 10 C5H5BFNO2 23, 43 C5H5BClNO2 C7H14ClNO4 10 C9H8O2 39 C11H19ClN2 12 C5H7NO2 45 C7H15N 11 C9H9N 32 C11H20O 27 C5H8BrClO 44 C7H16Cl2N2 11 C9H9NO 32 C12H14O 27 C5H8N4O12 36 C7H16N2 10 C9H9NO3 38 C12H14O2 26 C5H11NO2 44 C8H5N4 34 C9H9NO4 19, 20 C12H16N2O4 37 C5H12N2 10 C8H6BrN 21 C9H9N3O2 29 C12H17N 11 C6H2Cl2N2O4 37 C8H6ClIO2 18 C9H10ClNO3 17 C12H18N2 10 C6H3F3IN 43 C8H6ClN 30 C9H10FNO2 45 C12H20N2 12 C6H4BrNO 42 C8H6ClNO4 19 C9H10N2 16 C13H10N2O2 15 C6H4ClNO 42 C8H6FN 31 C9H10N2O2 34 C13H11N3 16 C6H4ClNO2 42 C8H6N2O2 29 C9H10N2O3 38 C14H22O3 26 C6H4ClNO3 40 C8H6N2O6 19 C9H10N2O4 24 C15H13NO 30 C6H4FNO 43 C8H7NO2S 34 C9H10O3 19 C15H26O 27 C6H4FNO2 43 C8H7NO3 34, 39 C9H10O4 19 C18H29NO2 37 C6H6N2O3 40 C8H7NO4 19, 20, 40 C9H11N 35 C18H31N 13 C6H8N2O8 36 C8H7NO5 41 C9H11NO2 18 C6H9NO6 36 C8H7N3O2 16 C9H11NO3 11 C9H12 45 C6H10O4 46 Page 24, 39 C8H8ClNO2 17, 37 C6H14N2 10 C8H8N2 12 C9H12N2O 12 C6H15NO 10 C8H8O 39 C9H12O3 22 C7H4ClIO2 18 C8H8O7 24 C9H13N 14 C7H4ClNO3 37 C8H9NO 12 C9H14N2 12 C7H4ClNO4 18 C8H9NO2 12, 17, 18, 21, 37 C9H14O3 25 C7H4Cl2N2 16 C8H9NO3 17, 37, 40 C9H15NO5 44 C7H4N2O2 38 C8H9N3 29 C9H16N2O2 11 C7H5BrN4 34 C8H9N3O 16 C9H16O 26, 27 C7H5NO4 41 C8H10 45 C9H17BO2 23, 28 C7H5NO5 19 C8H10O 40 C10H6F3NO2 33 C7H5N3O2 29 C8H11ClN2O2 24 C10H8ClNO2 31 C7H5N5O2 34 C8H11N 13 C10H8FNO2 31 C7H6BrNO2 21 C8H11NO 13 C10H9NO2 31, 32 C7H6BrNO3 37 C8H11NO2 13 C10H9NO6 20 C7H6ClNO2 17 C8H11N3O 35 C10H10N2O4 35 Registry Number Index CAS Page CAS Page CAS Page CAS Page CAS Page 56-91-7 21 768-70-7 40 4403-70-7 21 22990-77-8 10 69999-16-2 78-11-5 36 775-06-4 11 4498-67-3 29 24078-21-5 20 77256-78-1 37 87-33-2 36 823-76-7 26 4509-90-4 44 25235-85-2 30 77484-99-2 34, 39 88-05-1 14 934-32-7 16 4792-67-0 30 26116-12-1 10 78495-63-3 23 89-77-0 17 949-99-5 24 4894-75-1 27 26177-43-5 21 78607-36-0 42 89-87-2 37 1004-77-9 26 5306-85-4 24, 39 26759-46-6 17 82782-85-2 34 90-00-6 40 1006-94-6 32 5333-27-7 38 28188-41-2 21 82832-73-3 27 93-03-8 22 1011-65-0 31 5367-32-8 37 28888-44-0 35 91215-79-1 12 93-07-2 19 1068-90-2 44 5441-51-0 26 29865-49-4 45 93247-78-0 32 94-60-0 25 1073-62-7 21 5460-31-1 41 29865-52-9 45 98081-83-5 32 95-23-8 16 1125-60-6 34 5900-58-3 17 30273-11-1 12 98081-84-6 31 95-47-6 44 1193-81-3 26 6283-74-5 24 31181-89-2 42 100366-74-3 43 96-98-0 20 1204-32-6 32 6315-89-5 13 31252-42-3 11 105640-07-1 26 98-53-3 25 1215-59-4 30 6322-56-1 40 33696-00-3 37 108282-38-8 17 99-53-6 41 1728-46-7 25 6478-73-5 16 34160-40-2 42 113975-22-7 43 99-92-3 12 1792-40-1 16 6635-20-7 41 35794-11-7 11 126403-68-7 28 102-50-1 13 1955-46-0 20 6705-03-9 17 36404-88-3 42 126689-01-8 23, 28 106-42-3 45 1975-50-4 19 6967-12-0 29 36404-90-7 43 130561-87-4 28 108-38-3 44 2042-14-0 41 7254-19-5 30 38560-96-2 37 132873-57-5 24 108-67-8 45 2213-43-6 10 7356-11-8 20 39830-66-5 31 150114-41-3 33 110-46-3 44 2408-37-9 27 7409-18-9 21 40649-36-3 27 150208-70-1 11 327-20-8 33 2423-71-4 40 7597-18-4 29 42087-80-9 19 151831-21-9 15 393-55-5 43 2458-12-0 18 10242-00-9 33 42195-92-6 11 174669-73-9 23, 43 394-31-0 17 2516-96-3 18 10517-21-2 30 42454-06-8 41 197506-83-5 31 399-51-9 31 2550-36-9 25 10601-19-1 32 50541-93-0 10 351003-10-6 12 496-16-2 39 2687-25-4 13 13290-96-5 20 50593-30-1 29 381248-04-0 23, 42 504-17-6 35 2759-28-6 10 13331-23-2 23 50820-65-0 31 394223-19-9 15 540-80-7 44 2816-57-1 26 13433-00-6 10 51449-77-5 34 411235-57-9 23, 28 544-16-1 44 2835-98-5 40 13506-76-8 19 51449-86-6 34 581812-76-2 29 570-24-1 14 2941-78-8 17 14765-30-1 25 52130-17-3 18 620621-48-9 18 577-72-0 13 2942-59-8 42 16051-77-7 36 54087-03-5 42 677306-38-6 29 578-54-1 13 2999-46-4 45 16096-32-5 32 55011-60-4 44 688357-19-9 15 582-60-5 16 3001-72-7 35 16533-71-4 19 55038-01-2 39 796851-03-1 42 583-60-8 27 3002-94-6 28 16588-34-4 37 55289-06-0 19 871583-23-2 589-16-2 13 3034-38-6 35 16732-70-0 30 56043-01-7 12 1065010-87-8 23, 28 589-92-4 27 3102-70-3 12 16732-75-5 31 56207-36-4 38 1111213-54-7 23 591-24-2 27 3102-71-4 12 17159-79-4 25 56309-94-5 26 1222709-26-3 15 603-83-8 13 3102-87-2 14 17193-40-7 24 57233-86-0 24 603-85-0 40 3189-13-7 32 17422-33-2 30 58353-63-2 37 607-32-9 35 3420-02-8 32 18583-89-6 18 59382-59-1 19 610-78-6 40 3440-99-1 34 18595-14-7 18 61147-58-8 10 610-81-1 40 3698-83-7 37 18595-18-1 18 61203-82-5 25 619-14-7 19 3958-57-4 21 19094-56-5 18 61203-83-6 27 619-24-9 38 4048-33-3 10 20289-27-4 30 62638-06-6 25 635-46-1 35 4184-79-6 35 21578-58-5 16 63074-07-7 11 636-93-1 41 4255-62-3 26 21871-44-3 34 65999-76-0 12 652-67-5 24, 39 4333-56-6 28 22115-41-9 21 67014-36-2 16 766-17-6 11 4389-50-8 17 22374-89-6 11 68411-48-3 13 39 15 47 Parent Name Index Product Group Name Page Acetamide Page 3-(Aminomethyl)aniline 21 N-(3-Amino-2-methylphenyl)acetamide 12 4-sec-Butylaniline 12 1-Methylindol-3-acetamide 33 2-Ethylaniline 13 2-(1-Methyl-1H-indol-3-yl)acetamide 33 3,4-Dimethoxyaniline 13 N-(2-Methyl-3-nitrophenyl)acetamide 38 Dodecylaniline 13 Acetanilide 4-Ethylaniline 13 3-Amino-2-methylacetanilide 12 4-Methoxy-2-methylaniline 13 2-Methyl-3-nitroacetanilide 38 4-Methoxy-3-nitroaniline 13 2-Methyl-3-nitroaniline 13 2-Methyl-6-nitroaniline 14 2,4,6-Trimethylaniline 14 Acetic acid Coumaranacetic acid 39 2-(2,3-Dihydro-1-benzofuran-5-yl)acetic acid 39 Acetophenone Anisidine 4-Aminoacetophenone 12 4-Hydroxy-3-nitroacetophenone 40 4-Methyl-3-nitroacetophenone 38 Alanine 2-Methyl-para-anisidine 13 3-Nitro-para-anisidine 13 Anisole 4-Bromo-2-nitroanisole 37 3-(3-Hydroxyphenyl)-DL-alanine 11 3-Ethynylanisole 40 (S)-4-Nitrophenylalanine 24 3-Methyl-4-nitroanisole 37 (S)-4-Nitrophenylalanine methyl ester hydrochloride 24 4-(2-Nitropropyl)anisole 45 Alcohol Anthranilic acid 3,4-Dimethoxybenzyl alcohol 22 6-Amino-meta-anthranilic acid 17 Veratryl alcohol 22 4-Chloroanthranilic acid 17 4-Chloroanthranilic acid methyl ester 17 Amine 3-Aminobenzylamine 21 4,5-Dimethoxyanthranilic acid methyl ester 17 1H-Benzo[d]imidazol-2-amine 16 5-Hydroxyanthranilic acid 17 1-Benzyl-4-piperidinamine 10 4,6-Bis-(1-methylethyl)-1,3-benzenediamine 12 4-Azaindole-2-carboxylic acid methyl ester 15 2,3-Dimethylcyclohexanamine 11 4-Chloro-5-azaindole-2-carboxylic acid methyl ester 15 Isoquinolin-5-amine 34 4-Chloro-7-azaindole-2-carboxylic acid methyl ester 15 3-Methyl-1,2-benzenediamine 13 (R)-(−)-α-Methyl-4-nitrobenzylamine hydrochloride 24 3-Amino-4-methoxybenzaldehyde 12 (S)-(+)-α-Methyl-4-nitrobenzylamine hydrochloride 24 4-Chloro-3-nitrobenzaldehyde 37 1-Methyl-3-phenylpropylamine 11 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde 41 3-Nitrobenzylamine 21 5-Hydroxy-2-nitrobenzaldehyde 41 (R)-1-(4-Nitrophenyl)ethylamine hydrochloride 24 (S)-1-(4-Nitrophenyl)ethylamine hydrochloride 24 3-(Aminomethyl)nitrobenzene 21 4-Phenyl-2-butylamine 11 5-Bromo-2-methoxynitrobenzene 37 1-Piperidinamine 10 1-(Bromomethyl)-3-nitrobenzene 21 2-Piperidinemethylamine 10 2-Chloro-1,3-dimethyl-5-nitrobenzene 37 2,3,5,6-Tetramethyl-1,4-benzenediamine 14 3-Cyanonitrobenzene 38 2,4,6-Trimethyl-meta-phenylenediamine 12 1,3-Diamino-4,6-diisopropylbenzene 12 (S)-2-Amino-3-(4-nitrophenyl)propanoic acid 24 2,4-Diamino-1,3,5-trimethylbenzene 12 6-Amino-1-hexanol 10 1,5-Dichloro-2,4-dinitrobenzene 37 1,5-Diisopropyl-2,4-dinitrobenzene 37 1,2-Dimethylbenzene 44 Aniline 4-Acetylaniline 48 Product Group Name 12 Azaindole Benzaldehyde Benzene Parent Name Index Product Group Name Page Product Group Name Page 1,3-Dimethylbenzene 44 3-Hydroxy-4-nitrobenzoic acid 19 1,4-Dimethylbenzene 45 3-Methoxy-2-methylbenzoic acid 19 Dodecylnitrobenzene 37 2-Methyl-3-nitrobenzoic acid 19 1-Ethynyl-3-methoxybenzene 40 2-Methyl-3-nitrobenzoic acid methyl ester 19 1-Fluoro-4-(2-nitropropyl)benzene 45 2-Methyl-6-nitrobenzoic acid 19 4-Methoxy-2-methyl-1-nitrobenzene 37 3-Methyl-4-nitrobenzoic acid methyl ester 20 1-Methoxy-4-(2-nitropropyl)benzene 45 4-Methyl-3-nitrobenzoic acid 20 1,3,5-Trimethylbenzene 45 4-Methyl-3-nitrobenzoic acid methyl ester 20 Benzonitrile 1H-Benzimidazole 2-Amino-1H-benzimidazole 16 2-Amino-6-methylbenzonitrile 12 2-Anilino-1H-benzimidazole 16 2-(Bromomethyl)benzonitrile 21 5,6-Dichloro-1H-benzimidazole 16 3-(Bromomethyl)benzonitrile 21 5,6-Dimethyl-1H-benzimidazole 16 3-Nitrobenzonitrile 38 2-Methyl-5-nitro-1H-benzimidazole 16 2-Phenylamino-1H-benzimidazole 16 2H-Benzimidazole Boronic acid 2-Chloro-3-pyridineboronic acid 23 2-Chloropyridine-3-boronic acid 42 5-Amino-1,3-dihydro-2H-benzimidazol-2-one 16 (2-Chloro-3-pyridinyl)boronic acid 23 5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one 16 Cyclopropylboronic acid 23, 28 Cyclopropylboronic acid pinacol ester 23, 28 Benzimidazolinone 5-Amino-2-benzimidazolinone 16 2-Fluoro-6-methoxybenzeneboronic acid 23 5-Amino-6-methyl-2-benzimidazolinone 16 2-Fluoro-6-methoxyphenylboronic acid 23 2,3-Dihydrobenzofuran 39 2-Furanboronic acid 2-(Hydroxymethyl)benzofuran 39 Benzofuran 2-Fluoro-3-pyridineboronic acid Benzoic acid 23, 43 23 Bromide 2-Cyanobenzyl bromide 21 2-Amino-4-chlorobenzoic acid 17 3-Cyanobenzyl bromide 21 2-Amino-4-chlorobenzoic acid methyl ester 17 Cyclohexylmethyl bromide 25 4-Amino-5-chloro-2-methoxybenzoic acid methyl ester 17 Cyclopropyl bromide 28 2-Amino-4,5-dimethoxybenzoic acid methyl ester 17 Cyclopropylzinc bromide 28 2-Amino-5-hydroxybenzoic acid 17 3-Nitrobenzyl bromide 21 2-Amino-5-methoxybenzoic acid 17 2-Amino-5-methylbenzoic acid 17 Butanoic acid 4-hydroxybutyl ester 44 2-Amino-6-methylbenzoic acid 17 Nitrous acid tert-butyl ester 44 3-Amino-2-methylbenzoic acid 18 3-Amino-2-methylbenzoic acid methyl ester 18 6-Bromopyridine-2-carbaldehyde 42 3-Amino-4-methylbenzoic acid 18 2-Chloropyridine-3-carbaldehyde 42 3-Amino-4-methylbenzoic acid methyl ester 18 5-Chloropyridine-2-carbaldehyde 42 4-(Aminomethyl)benzoic acid 21 6-Chloropyridine-2-carbaldehyde 42 4-Amino-3-methylbenzoic acid methyl ester 18 2-Fluoropyridine-3-carbaldehyde 43 2-Chloro-5-iodobenzoic acid 18 5-Methoxy-1H-indole-3-carbaldehyde 32 2-Chloro-5-iodobenzoic acid methyl ester 18 2-Chloro-5-nitrobenzoic acid 18 4-Amino-1H-indazole-1-carboxylic acid methyl ester 29 4-Chloro-2-nitrobenzoic acid methyl ester 19 2-Chloropyridine-3-carboxylic acid 42 3,4-Dimethoxybenzoic acid 19 1,3-Cyclohexanedicarboxylic acid dimethyl ester 25 3,5-Dinitro-4-methylbenzoic acid 19 1,4-Cyclohexanedicarboxylic acid dimethyl ester 25 Butyl ester Carbaldehyde Carboxylic acid 49 Parent Name Index Product Group Name Page Page 4-Cyclohexanonecarboxylic acid ethyl ester 25 Cyclopropylboranediol 23, 28 2-Fluoropyridine-3-carboxylic acid 43 Cyclopropylboronic acid 23, 28 31 Cyclopropylboronic acid pinacol ester 23, 28 3-Formyl-1H-indole-5-carboxylic acid methyl ester 4H-Furo[3,2-b]pyrrole-5-carboxylic acid methyl ester 34, 39 Cyclopropyl bromide 28 Cyclopropyllithium 28 1H-Indole-4-carboxylic acid methyl ester 31 1H-Indole-5-carboxylic acid methyl ester 31 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1H-Indole-6-carboxylic acid methyl ester 31 Cyclopropylzinc bromide 1H-Indole-7-carboxylic acid methyl ester 32 Potassium cyclopropyl-1-trifluoroborate 5-Methoxy-1H-indole-3-carbaldehyde 32 DBN 35 1-Methyl-1H-indole-6-carboxylic acid methyl ester 32 (+)-Diacetyl-L-tartaric acid anhydride 24 4-Methyl-1H,4H-pyrrolo[3,2-b]pyrrole-2-carboxylic acid methyl ester 34 3,6-Diaminodurene Pyrazolo[1,5-a]quinoline-2-carboxylic acid methyl ester 15 1,4:3,6-Dianhydro-D-sorbitol 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid methyl ester 34 23, 28 28 23, 28 14 24, 39 1,4:3,6-Dianhydro-D-sorbitol dimethyl ether 24 1,5-Diazabicyclo[4.3.0]non-5-ene Chloride 35 Diketone 5-Bromopentanoyl chloride 44 5-Bromovaleryl chloride 44 (3R,4R)-3,4-Diacetoxytetrahydrofuran-2,5-dione 24 39 6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione 35 Coumaran 5,6-Dimethyl-1H-benzo[d][1,2,3]triazole hydrate Cresol 35 Dimethyl ether 6-Amino-meta-cresol 40 3-Nitro-ortho-cresol 41 4-Aminocatechol dimethyl ether 13 3-Nitro-para-cresol 41 1,4:3,6-Dianhydro-D-sorbitol dimethyl ether 39 4-Nitro-ortho-cresol 41 Cyclohexanone Isosorbide dimethyl ether 24, 39 Dottisol® 24, 39 Ethanone (Bromomethyl)cyclohexane 25 2-sec-Butylcyclohexanone 25 1-(4-Aminophenyl)ethanone 12 2-tert-Butylcyclohexanone 25 1-Cyclohexyl-1-ethanone 26 4-Butylcyclohexanone 25 1-(4-Methyl-3-nitrophenyl)ethanone 38 4-tert-Butylcyclohexanone 25 Ethyl 2-isocyanoacetate 2,6-Dimethylcyclohexanone 26 Hydrochloride 4,4-Dimethylcyclohexanone 26 4-Amino-N-ethyl-N-isopropylaniline hydrochloride 12 4-(1,4-Dioxaspiro[4.5]dec-8-yl)cyclohexanone 26 Aminomalonic acid diethyl ester hydrochloride 10 4-Ethylcyclohexanone 26 3-(Aminomethyl)nitrobenzene hydrochloride 21 4-(4-Hydroxyphenyl)cyclohexanone 26 (S)-2-Amino-3-(4-nitrophenyl)propanoic acid methyl ester hydrochloride 24 2-Isopropylcyclohexanone 26 Benzylhydrazine hydrochloride 21 2-Methylcyclohexanone 27 1,4-Diazabicyclo[3.2.2]nonane dihydrochloride 11 3-Methylcyclohexanone 27 N-Ethyl-N-isopropyl-para-phenylenediamine hydrochloride 12 4-Methylcyclohexanone 27 3-Nitrobenzylamine hydrochloride 21 4-Pentylcyclohexanone 27 4-Nitro-1H-imidazole 4-Phenylcyclohexanone 27 1H-Indazole 4-Propylcyclohexanone 27 6-Amino-1H-indazole 29 trans-4-(4'-Propylcyclohexyl)cyclohexanone 27 1H-Indazole-3-carboxylic acid 29 2,2,6-Trimethylcyclohexanone 45 35 27 1H-Indazole-4-carboxylic acid 29 1-Cyclohexylethanol 26 6-Nitro-1H-indazole 29 Cyclohexyl methyl ketone 26 Cyclopropyl 50 Product Group Name 2H-Indazole 2-Methyl-2H-indazol-6-amine 29 Parent Name Index Product Group Name 6-Amino-2-methyl-2H-indazole Page 29 Product Group Name 3,4-Dimethoxybenzenemethanol 3-Methoxyphenylacetylene 1H-Indole Page 22 40 Nicotinic acid 5-(Benzyloxy)-1H-indole 30 7-(Benzyloxy)-1H-indole 30 2-Chloronicotinic acid 42 5-Bromo-1H-indole-2-carboxylic acid 30 2-Fluoronicotinic acid 43 5-Bromo-1H-indole-2-carboxylic acid ethyl ester 30 4-Chloro-1H-indole 30 1,4:3,6-Dianhydro-D-sorbitol 2,5-dinitrate 36 5-Chloro-1H-indole-2-carboxylic acid 30 1,4:3,6-Dianhydro-D-sorbitol 5-nitrate 36 5-Chloro-1H-indole-2-carboxylic acid ethyl ester 30 Isosorbide dinitrate 36 6-Chloro-1H-indole 30 Isosorbide-5-mononitrate 36 6-Chloro-1H-indole-2-carboxylic acid 31 Pentaerythritol tetranitrate 36 6-Chloro-1H-indole-2-carboxylic acid methyl ester 31 6-Fluoro-1H-indole 31 Butyl nitrite 44 6-Fluoro-1H-indole-2-carboxylic acid methyl ester 31 tert-Butyl nitrite 44 3-Formyl-1H-indole-5-carboxylic acid methyl ester 31 Isoamyl nitrite 44 1H-Indole-4-carboxylic acid methyl ester 31 3-Methylbutyl nitrite 44 1H-Indole-5-carboxylic acid methyl ester 31 5-Nitroguaiacol 41 1H-Indole-6-carboxylic acid methyl ester 31 Nitropenta 36 1H-Indole-7-carboxylic acid methyl ester 32 5-Nitrovanillin 41 5-Methoxy-1H-indole 32 4-Nitro-2,6-xylenol 40 5-Methoxy-1H-indole-3-carbaldehyde 32 PETN 36 6-Methoxy-1H-indole 32 Phenol 6-Methoxy-1H-indole-2-carboxylic acid methyl ester 32 4-Acetyl-2-nitrophenol 40 1-Methyl-1H-indole-6-carboxylic acid methyl ester 32 2-Amino-5-methylphenol 40 4-Methyl-1H-indole 32 2-Amino-3-nitrophenol 40 6-Methyl-1H-indole 32 4-Amino-3-nitrophenol 40 6-Nitro-1H-indole-2-carboxylic acid 33 4-Chloro-3-nitrophenol 40 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid 33 2,6-Dimethyl-4-nitrophenol 40 ISMN 36 2-Ethylphenol 40 2-Isocyanoacetic acid ethyl ester 45 2-Methoxy-5-nitrophenol 41 24, 39 2-Methyl-3-nitrophenol 41 Isosorbide Nitrate Nitrite 24, 39 2-Methyl-4-nitrophenol 41 Ketoketal 26 4-Methyl-3-nitrophenol 41 3,5-Lupetidine 11 2-(1H-Tetrazol-5-yl)phenol 34 Dimethyl isosorbide Isophthalic acid Malonate Diethyl acetamidomalonate 44 Diethyl aminomalonate hydrochloride 10 5-Nitroisophthalic acid dimethyl ester 20 5-Nitroisophthalic acid monomethyl ester 20 Piperazine Malonic acid Acetamidomalonic acid diethyl ester 44 1-Benzylpiperazine 10 Acetylaminomalonic acid diethyl ester 44 1-(Tetrahydro-2-furoyl)piperazine 11 Mesidine 14 THF-Piperazine 11 Mesitylene 45 2,4-Diaminomesitylene 12 Methanol 1-Benzofuran-2-ylmethanol 39 Piperidine 4-Amino-1-benzylpiperidine 10 cis-1-Amino-2,6-dimethylpiperidine 10 2-(Aminomethyl)piperidine 10 51 Parent Name Index Product Group Name Page 3-Methoxy-6-nitrotoluene Page 37 1-Aminopiperidine 10 4-Benzylpiperidine 11 cis-2,6-Dimethylpiperidine 11 4-Amino-meta-toluic acid methyl ester 18 3,5-Dimethylpiperidine 11 6-Amino-meta-toluic acid 17 3-Amino-ortho-toluic acid 18 3-Amino-ortho-toluic acid methyl ester 18 6-Amino-ortho-toluic acid 17 3-Amino-para-toluic acid 18 Potassium trifluoroborate Potassium cyclopropyl-1-trifluoroborate Potassium 5-methylfuran-2-trifluoroborate 23, 28 23 Propane Toluic acid Bromocyclopropane 28 3-Amino-para-toluic acid methyl ester 18 1-(4-Fluorophenyl)-2-nitropropane 45 3,5-Dinitro-para-toluic acid 19 1-(4-Methoxyphenyl)-2-nitropropane 45 3-Methoxy-ortho-toluic acid 19 trans-4'-Propylbi(cyclohexan)-4-one 27 4-Nitro-meta-toluic acid methyl ester 20 3-Nitro-ortho-toluic acid 19 Pyridine 6-Bromo-2-formylpyridine 42 3-Nitro-ortho-toluic acid methyl ester 19 7-Bromopyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester 15 6-Nitro-ortho-toluic acid 19 2-Chloro-3-formylpyridine 42 3-Nitro-para-toluic acid 20 5-Chloro-2-formylpyridine 42 3-Nitro-para-toluic acid methyl ester 20 6-Chloro-2-formylpyridine 42 2-Chloro-3-iodopyridine 42 3-Nitro-ortho-toluidine 13 6-Chloropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester 15 6-Nitro-ortho-toluidine 14 4-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester 15 DL-m-Tyrosine 11 4-Chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester 15 Veratric acid 19 2,5-Dichloro-4-iodopyridine 42 2-Fluoro-3-formylpyridine 43 2-Fluoro-3-iodopyridine 43 2-Chloro-5-nitro-meta-xylene 37 2-Iodo-6-(trifluoromethyl)pyridine 43 4-Nitro-meta-xylene 37 Pyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester 15 meta-Xylene 44 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester 15 ortho-Xylene 44 35 para-Xylene 44 4,6-Dihydroxy-2-mercaptopyrimidine Pyrrolidine 2-(Aminomethyl)-1-ethylpyrrolidine 10 N-Ethyl-2-aminomethylpyrrolidine 10 Quinoline 5-Aminoisoquinoline 34 5-Nitroisoquinoline 35 1,2,3,4-Tetrahydroquinoline 35 1H-Tetrazole 5-(3-Bromophenyl)-1H-tetrazole 34 5-(2-Hydroxyphenyl)-1H-tetrazole 34 5-(2-Methylphenyl)-1H-tetrazole 34 5-(3-Nitrophenyl)-1H-tetrazole 34 2-Thiobarbituric acid 35 Toluene 52 Product Group Name 4-Acetyl-2-nitrotoluene 38 2,3-Diaminotoluene 13 Toluidine 6-Aminoveratric acid methyl ester 17 Xylene Notes 53 Notes 54 Contact Switzerland Dottikon Exclusive Synthesis AG P.O. Box, 5605 Dottikon Switzerland Tel +41 56 616 81 11 Fax +41 56 616 81 20 info@dottikon.com www.dottikon.com United States of America Dottikon Exclusive Synthesis AG US Rep-Office 803 W. Trenton Avenue, Suite 1 Morrisville, PA 19067 USA Tel +1 215 295 2295 Fax +1 215 295 2577 info.us@dottikon.com www.dottikon.com 55 D F Zurich A SWITZERLAND F I Zurich Exit Birr (from Basle) Basle A3 N Exit Mägenwil (from Berne) A1 Mägenwil Luzern Berne Exit Mägenwil (from Zurich) Dottikon village Lu ze rn Othmarsingen nstr. brun Hem Red building Train station Your Specialist for Hazardous Reactions. 010611 Dottikon/Dintikon