Advanced Care Paramedic Pocket Reference Guide 2011 v. 1.1 CEPCP 2 This pocket reference guide is to be used for reference only. Refer to the current medical directives for all treatment decisions. If there are inconsistencies between this reference guide and the current directives always refer to the medical directives. For questions, comments, or suggestions for improvements, please contact us at: Website (follow ‘contact us’ link): www.cepcp.ca Administration Office: 95A Simcoe St. S. Oshawa, ON Mailing Address: Central East Prehospital Care Program Lakeridge Health Oshawa 1 Hospital Court Oshawa, ON L1G 2B9 Phone: (905) 433-4370 Fax: (905) 721-4737 Toll free: 1-866-423-8820 3 Table of Contents: Mandatory Patches and BHP names............................!4 - 5 Adult Cardiac Arrest......................................................!6 - 7 Pediatric Cardiac Arrest................................................!8 - 9 Trauma Cardiac Arrest..................................................!10 Tension Pneumothorax.................................................!11 Neonatal Resuscitation.................................................!12 - 13 Hypothermia Cardiac Arrest..........................................!14 Foreign Body Airway Obstruction..................................15 Return of Spontaneous Circulation...............................!16 IV and Fluid Therapy.....................................................!17 Pediatric / Adult IO........................................................!18 Central Venous Access.................................................!19 Endotracheal Intubation................................................!20 Supraglottic Airway........................................................!21 Moderate to Severe Allergic Reaction..........................!22 - 23 Croup............................................................................!24 Bronchoconstriction......................................................!25 CPAP.............................................................................!26 Acute Cardiogenic Pulmonary Edema..........................!27 Cardiac Ischemia..........................................................!28 - 29 STEMI Bypass..............................................................!30 - 31 Cardiogenic Shock........................................................!32 - 33 Bradycardia...................................................................!34 - 35 Procedural Sedation.....................................................!36 Combative Patient........................................................!37 Tachydysrhythmia.........................................................!38 - 39 Seizure..........................................................................!40 - 41 Opioid Toxicity...............................................................!42 Electronic Control Device Probe Removal....................!43 Hypoglycemia................................................................44 - 45 Nausea / Vomiting.........................................................46 - 47 Pain...............................................................................48 Special Events...............................................................49 - 53 Reference Materials 4 Advanced Care Paramedics will now be required to patch for the following • Medical Cardiac Arrest Directive patch after 3 rounds of epinephrine or unable to get a drug route after 3 analyses • Trauma Cardiac Arrest Directive patch for authorization to apply the TOR if applicable • Symptomatic Bradycardia Directive patch for authorization to proceed with transcutaneous pacing and/or a dopamine infusion • Tachydysrhythmia Directive patch for authorization to proceed with lidocaine or monomorphic wide complex regular rhythm for adenosine • Tachydysrhythmia Directive patch for authorization to proceed with synchronized cardioversion • Intravenous and Fluid Therapy Directive patch for authorization to administer IV NaCl bolus to patients <12 years with suspected Diabetes Ketoacidosis (DKA) • Opioid Toxicity Directive patch for authorization to proceed with naloxone • Tension pneumothorax Directive patch for authorization to perform needle thoracostomy AUXILIARY DIRECTIVES • Combative Patient Directive patch for authorization to proceed with midazolam if unable to assess the patient for normotension or reversible causes • Nausea and Vomiting Directive patch for authorization to proceed with dimenhydrinate for patient weighing <25kg IV or IM Central East Prehospital Care Program Markham: For reference only 5 6 Central East Prehospital Care Program For reference only Adult Cardiac Arrest Indications Adult Cardiac Arrest Non-traumatic cardiac arrest CPR ongoing throughout call Minimize Interruptions 100 - 120 per minute At least 2 inches depth 30:2 Adult > 8 years only (if 8-12 years old use DRUG dosages from pediatric arrest page) Defibrillate VF/VT every 2 mins Zoll LP12 / LP15 200 joules (all shocks) 200, 300, 360 joules Adult > 12 years only Drug Dose Epinephrine every 4 mins patch after 3rd dose IO/CVAD/IV (preferred) 1.0 mg ETT (if above delayed > 5 mins) 2.0 mg IM (if suspected anaphylaxis) 0.01 mg/kg 1:1,000 (max 0.5 mg) single dose Lidocaine for recurrent V-fib/VT (typically after 3rd shock) repeat after 4 mins 2 doses max Bolus for PEA or any other rhythm where hypovolemia is suspected IO/IV/CVAD 1.5 mg/kg typically supplied 20 mg/ml ETT 3.0 mg/kg 20 ml/kg to 2,000 max re-assess every 250 ml ETT or King LT should be inserted where more than OPA/BVM is required, without interrupting CPR. Once inserted, begin continuous compressions and ventilate asynchronously at 6-8 breaths / min. monitor ETCO2: 10 - 15 mmHg - poor prognosis, confirm compressions are adequate 20 - 30 mmHg - improved prognosis, indicates good CPR quality > 35 mmHg - excellent CPR / prognosis, check for palpable pulse large spike to above normal values - probable ROSC, check for pulse For reference only 7 Central East Prehospital Care Program Lidocaine Volume per weight based on 100 mg/5 ml 40 kg = 3.0 ml 105 kg = 7.88 ml 45 kg = 3.34 ml 110 kg = 8.25 ml 50 kg = 3.75 ml 115 kg = 8.62 ml 55 kg = 4.13 ml 120 kg = 9.0 ml 60 kg = 4.5 ml 125 kg = 9.38 ml 65 kg = 4.88 ml 130 kg = 9.75 ml 70 kg = 5.25 ml 135 kg = 10.13 ml 75 kg = 5.63 ml 140 kg = 10.5 ml 80 kg = 6.0 ml 145 kg = 10.88 ml 85 kg = 6.36 ml 150 kg = 11.25 ml 90 kg = 6.75 ml 155 kg = 11.63 ml 95 kg = 7.13 ml 160 kg = 12.00 ml 100 kg = 7.5 ml 165 kg = 12.37 ml King LT Reference Notes: Size Colour Patient Amt of air in cuff #3 Yellow 4-5 ft tall 45 - 60 ml #4 #5 Red Purple 5-6 ft tall ≥ 6 ft tall Confirmation Methods 60 - 80 ml 70 - 90 ml Primary • Auscultation Confirm supraglottic airway placement. • Chest rise Secondary • ETCO2 • Other 8 Central East Prehospital Care Program For reference only Pediatric Cardiac Arrest Pediatric Cardiac Arrest Indications Non-traumatic cardiac arrest CPR ongoing throughout call Minimize Interruptions 100 - 120 per minute 1/3 to 1/2 of chest diameter for children and infants 30:2 if single rescuer 15:2 for infants and children if two rescuer Pediatric ≥ 30 days - < 8 years only (if 8-< 12 years old use adult joule settings, but drug dosages below) Drug Dose Defibrillate VF/VT 2 joules / kg ( 1st shock) 4 joules / kg (subsequent shocks) every 2 mins (pediatric pads if < 15 kg) Pediatric ≥ 30 days - < 12 years only Drug Dose Epinephrine every 4 mins patch after 3rd dose IO/IV (preferred) 0.01 mg/kg 1:10,000 (min 0.1 mg) 0.1 ml / kg ETT (if above delayed > 5 mins) 0.1 mg/kg 1:1,000 (min 1 mg) 0.1 ml / kg (max 2 mg) IM (if suspected anaphylaxis) 0.01 mg/kg 1:1,000 (max 0.5 mg) single dose Lidocaine < 40kg for recurrent VF/VT (typically after 3rd shock) repeat after 4 mins 2 doses max Bolus for PEA or any other rhythm where hypovolemia is suspected IO/IV 1.0 mg/kg typically supplied 20 mg/ml ETT 2.0 mg/kg 20 ml/kg to 2,000 max re-assess every 100 ml ETT should be inserted where more than OPA/BVM is required, without interrupting CPR. Tube size = 4 + (age / 4) Depth = 3 x ETT diameter Once inserted, begin continuous compressions and ventilate asynchronously at 6-8 breaths / min. monitor ETCO2: 10 - 15 mmHg - poor prognosis, confirm compressions are adequate 20 - 30 mmHg - improved prognosis, indicates good CPR quality > 35 mmHg - excellent CPR / prognosis, check for palpable pulse large spike to above normal values - probable ROSC, check for pulse Central East Prehospital Care Program For reference only 9 10 Central East Prehospital Care Program For reference only Trauma Cardiac Arrest Trauma Cardiac Arrest Indications Cardiac arrest secondary to severe blunt or penetrating trauma. Protect C-spine Begin chest compressions Attach SAED pads Begin PPV with BVM After 2 minutes interpret rhythm If in VF/VT Defibrillate once ≥ 30 days - < 8 years - 2 joules / kg ≥ 8 yr - 200 joules Yes If in PEA determine drive-time to nearest hospital Less than 30 minutes drive-time to nearest ER? No ASYSTOLE No 16 years or older? Yes Continue CPR Immobilize Patient Transport to Hospital Continue CPR Patch to BHP for possible trauma TOR For reference only 11 Central East Prehospital Care Program Tension Pneumothorax Suspected tension pneumothorax and critically ill or VSA and absent or severely diminished breath sounds on the affected side(s). Clinical Parameters Vital Sign Parameters SBP < 90 or VSA N/A PATCH - for needle thoracostomy Notes: Needle thoracostomy may only be performed at the second intercostal space in the midclavicular line. • Using three finger widths (average adult fingers) from the centre of the sternum provides an accurate, easily remembered landmarking method. • The rib adjacent to the angle of louis is the second rib, the space below this rib is the second intercostal space. • Chest-wall thickness may be as much as 2 3/4" Tension Pneumothorax Indications Neonatal Resuscitation 12 Central East Prehospital Care Program For reference only Central East Prehospital Care Program For reference only 13 Hypothermic Arrest 14 Central East Prehospital Care Program For reference only Hypothermia Cardiac Arrest Indications Cardiac arrest secondary to severe hypothermia. Clinical Parameters Not obviously dead as per BLS standard No DNR Interventions Defibrillate once if the patient is in VF/VT ≥ 30 days to < 8 years old - 2 joules / kg ≥ 8 years old - 200 joules Transport to the closest appropriate facility without delay following the first rhythm interpretation. Central East Prehospital Care Program For reference only 15 Foreign body airway obstruction Cardiac arrest secondary to an airway obstruction. Clinical Parameters Not obviously dead as per BLS standard No DNR Interventions Attempt to clear airway with BLS maneuvers and /or laryngoscope Magill forceps Defibrillate once if the patient is in VF/VT ≥ 30 days to < 8 years old - 2 joules / kg ≥ 8 years old - 200 joules If the obstruction cannot be removed, transport to the closest appropriate facility without delay following the first rhythm interpretation. If the patient is in cardiac arrest following removal of the obstruction, initiate management as a medical cardiac arrest. Foreign Body Airway Obstr. Indications 16 Central East Prehospital Care Program For reference only Return of Spontaneous Circulation (ROSC) Indications ROSC ROSC after resuscitation was initiated Clinical Parameters SBP < 90 mmHg Bolus: • Clear chest / no fluid overload Dopamine: • No Allergy/Sensitivity • No Pheochromocytoma • No Tachydysrhythmias (excl. sinus tach) • No Mechanical shock states (i.e: tension pneumothorax, pulmonary embolism, pericardial tamponade) • No Hypovolemia Adult Doses (≥12 years) Drug Initial Dose Reassess Q 10 ml/kg 250 ml Bolus IV only Drug Initial Dopamine IV only 5 mcg/kg/min Increase by 5 mcg/kg/min Max 1,000 ml every to max. 5 mins 20 mcg/kg/min Pediatric Doses Drug Initital Dose Bolus IV only 10 ml/kg Drug Initial Dopamine IV only 5 mcg/kg/min Reassess Q 100 ml Increase by 5 mcg/kg/min Max 1,000 ml every 5 mins to max. 20 mcg/kg/min Notes: Titrate oxygenation to ≥ 94% Avoid hyperventilation and target an ETCO2 of 35-40 mmHg with continuous capnography. Consider 12 lead ECG. For reference only 17 Central East Prehospital Care Program IV and Fluid Therapy Indications Actual or potential need for IV medication or fluid therapy Actual or potential need for intravenous medication or fluid therapy Clinical Parameters IV and Fluid IV Start: No fracture proximal to IV site Bolus: No signs of fluid overload SBP < 90 Adult Doses ≥ 12 years Drug Initital Dose TKVO IV/IO/CVAD Bolus IV/IO/CVAD Q Repeat Max 30 - 60 ml/hr 20 ml/Kg Reassess q 250 ml N/A 2,000 ml Repeat Dose Max N/A 2,000 ml Pediatric Doses < 12 years, Use micro drip or Buretrol Drug Initital Dose TKVO IV/IO 15 ml/hr Bolus IV/IO 20 ml/Kg Q Reassess q 100 ml Notes: PATCH to BHP for authorization to administer IV bolus to patients < 12 years with suspected Diabetic Ketoacidosis (DKA). 18 Central East Prehospital Care Program For reference only Pediatric / Adult Intraosseous Medical Directive Indications: Pediatric / Adult IO Actual or potential need for intravenous medication or fluid therapy AND Intravenous access is unobtainable AND Patient is in cardiac arrest or near-arrest state Clinical Parameters Vital Sign Parameters IO Start: No fracture or crush injuries or known replacement / prosthesis proximal to the access site. N/A Notes: Jamshidi Cook : ≥ 1 year use 15/16 gauge needle < 1 year use 18 gauge needle EZ IO: Pink 15 mm 3-39 kg Blue 25 mm ≥ 40 kg Yellow 45 mm ≥ 40 kg with excessive tissue over targeted insertion site For reference only 19 Central East Prehospital Care Program Central Venous Access Device Indications: Clinical Parameters Vital Sign Parameters CVAD Access: Patient has pre-existing, accessible central venous catheter in place N/A Notes: CVAD Procedure : two 10 cc syringes, one empty and one with 10 cc saline drawn up several alcohol swabs a primed AIR FREE IV set clean, preferably sterile, gloves Prepare equipment Close clamps Wipe med-port and luer lock with alcohol swab. Remove med-port from luer lock Attach the empty syringe, Open the clamp (if present) Withdraw whatever fluid is within the catheter until approximately 2cc of blood is in the syringe Close clamp Attach the syringe with saline Open the clamp, and slowly inject the saline using a push/pull technique. If resistance is met discontinue attempt Close clamp Attach the IV line Open clamp Run the IV as per normal, administering IV drugs through the medication ports on the IV set Central Venous Access Actual or potential need for intravenous medication or fluid therapy AND Intravenous access is unobtainable AND Patient is in cardiac arrest or near-arrest state 20 Central East Prehospital Care Program For reference only Endotracheal Intubation Indications Need for ventilatory assistance or A/W control and other A/W management is inadequate or ineffective. Clinical Parameters Endotracheal Intubation • No allergy or sensitivity to drugs administered. • If < 50 years old and having asthma exacerbation, do not intubate unless in or near cardiac arrest. Nasal ETT: • ≥ 8 years old • No suspected basal skull or mid-face fracture • No uncontrolled epistaxis • Not under anticoagulant therapy (ASA excluded) • No bleeding disorders • Not apneic Lidocaine Topical Spray: • For nasal/oral ETT • Not used if patient is unresponsive Drug Dose Lidocaine up to 20 sprays 10 mg/spray 5 mg/kg max Topical Xylometazoline • Use for nasal ETT only Max Drug Dose 1 dose Xylometazoline 2 sprays / nare Confirmation Methods At least two primary and one secondary ETT placement confirmation methods must be used. Primary • Visualization • Auscultation • Chest rise Max 1 dose Secondary • ETCO2 • EDD • Other Notes: An intubation attempt is defined as insertion of the laryngoscope blade into the mouth. The maximum number of ETT and SGA attempt are two. If the patient has a pulse, an ETCO2 device (quantitative or qualitative) must be used for ETT placement confirmation. ETT placement must be reconfirmed immediately after every patient movement. Central East Prehospital Care Program For reference only 21 Supraglottic Airway Indications Need for ventilatory assistance OR airway control AND Other airway management is inadequate OR ineffective OR unsuccessful Clinical Parameters GCS 3 No gag reflex Able to clear the airway (with suctioning etc.) No active vomiting No airway edema No stridor No caustic ingestion Supraglottic Airway • • • • • • • Two attempts maximum. An 'attempt' is defined as the insertion of the supraglottic airway into the mouth. Confirmation Methods Primary • Auscultation Confirm supraglottic airway placement. • Chest rise Notes: Size Colour Patient Amt of air in cuff #3 Yellow 4-5 ft tall 45 - 60 ml #4 #5 Red Purple 5-6 ft tall ≥ 6 ft tall 60 - 80 ml 70 - 90 ml Secondary • ETCO2 • Other 22 Central East Prehospital Care Program For reference only Moderate to SevereAllergic Reaction Indications Exposure to a probable allergen and signs and/or symptoms of a moderate to severe allergic reaction (including anaphylaxis). Clinical Parameters No allergy or sensitivity to any drug administered. Allergic Reaction Epinephrine: Use for anaphylaxis only Adult Doses ( > 50 Kg) Drug Initial Dose Epinephrine IM 0.5 mg Diphenhydramine IV/IM 50 mg > 50 kg Q > 50 kg Repeat Max N/A N/A 1 dose N/A N/A 1 dose Pediatric Doses Drug Epinephrine IM Diphenhydramine IV/IM Initital Dose 0.01 mg/kg Max 0.5 mg 25 mg > 25 - < 50 kg (if < 25 kg Patch) Q Repeat Dose Max N/A N/A 1 dose N/A N/A 1 dose Notes: Epinephrine should be the first drug administered in anaphylaxis. The epinephrine dose may be rounded to the nearest 0.05 mg. Central East Prehospital Care Program For reference only 23 Epinephrine 1:1,000 0.01 mg/kg Rounded to the nearest 0.05 ml 24 Central East Prehospital Care Program For reference only Croup Indications Severe respiratory distress and stridor at rest and current history of URTI and barking cough or recent history of a barking cough. Croup Clinical Parameters • < 8 years old • No allergy or sensitivity to epinephrine • Heart rate less than 200 / min Pediatric Doses Drug Epinephrine ≥ 1 year old Epinephrine < 1 year old > 5 kg or more Epinephrine < 1 year < 5 kg Dose Max 5.0 mg 1 dose (5 ml) 2.5 mg (2.5 ml) 0.5 mg (mix with 2 ml of saline to make 2.5 ml) Notes: The minimum initial volume for nebulization is 2.5 ml. 1 dose 1 dose For reference only 25 Central East Prehospital Care Program Bronchoconstriction Indications Respiratory distress and suspected bronchoconstriction. Clinical Parameters No allergy or sensitivity to any drug administered. Epinephrine: • BVM ventilation is required • Must have a history of asthma Drug Salbutamol MDI ≥ 25 kg Salbutamol Nebulized ≥ 25 kg Epinephrine IM ≥ 50 kg Initital Dose Q Repeat Max 800 mcg 5-15 min 800 mcg 3 doses 5 mg 5-15 min 5 mg 3 doses 0.5 mg N/A N/A 1 dose Pediatric Doses Drug Salbutamol MDI < 25 kg Salbutamol Nebulized < 25 kg Epinephrine IM < 50 kg Initital Dose Q Repeat Dose Max 600 mcg 5-15 min 600 mcg 3 doses 2.5 mg 5-15 min 2.5 mg 3 doses N/A 1 dose 0.01 mg/kg Max 0.5 mg Notes: Epinephrine should be the first drug administered if the patient is apneic. Salbutamol MDI may be administered subsequently using a BVM MDI adapter (if available). Nebulization is contraindicated in patients with a known or suspected fever or in the setting of a declared febrile respiratory illness outbreak by the local medical officer of health. When administering salbutamol MDI, the rate of administration should be 100 mcg approximately every 4 breaths. A spacer should be used when administering salbutamol MDI (if available). Bronchoconstriction Adult Doses 26 Central East Prehospital Care Program For reference only CPAP Indications Severe respiratory distress AND; Signs and/or symptoms of acute pulmonary edema OR COPD CPAP Clinical Parameters • • • • • ≥18 years old Able to sit upright and cooperate Respiratory rate ≥ 28 / minute SpO2 < 90% OR accessory muscle use SBP ≥ 100 • • • • • Not asthma exacerbation No unprotected or unstable airway Not suspected pneumothorax No major trauma or burns to the head or torso No Tracheostomy Adult Doses ≥18 years Start at Increase by 5 cmH20 2.5 cmH20 or 15 lpm if Boussignac 5 or lpm if Boussignac Q 5 mins Max 15 cmH20 or 25 lpm if Boussignac If device has adjustable FiO2, begin at lower setting and only increase if SpO2 remains < 92% despite treatment and/or CPAP pressure of 10 cmH2O. Notes: Confirm CPAP by manometer if available For reference only 27 Central East Prehospital Care Program Acute Cardiogenic Pulmonary Edema Indications Moderate to severe respiratory distress from suspected acute cardiogenic pulmonary edema Clinical Parameters Vital Sign Parameters No allergy or sensitivity HR: 60 - 159 No phosphodiesterase inhibitors* in past 48 hrs SBP ≥ 100 If SBP < 140 patient must have prior nitroglycerin use or IV established SBP drops no more than 1/3 of initial value Drug Initial Dose Nitroglycerin BP 100 - 140 Nitroglycerin BP ≥ 140 Q Repeat Dose Max 0.4 mg S/L 5 min 0.4 mg 6 doses 0.4 mg S/L 5 min 0.4 mg 6 doses 0.8 mg S/L 5 min 0.8 mg 6 doses NO History or IV Nitroglycerin BP ≥ 140 WITH History or IV Notes: Perform 12 / 15 lead * Phosphodiesterase inhibitors: - Sidenafil: Viagra, Revatio (for pulmonary hypertension) - Tadalafil: Cialis, Adcirca (for pulmonary hypertension) - Vardenafil: Levitra, Staxyn Acute Pulmonary Edema Adult Dose ≥18 years only 28 Central East Prehospital Care Program For reference only Cardiac Ischemia Medical Directive Indications Suspected Cardiac Ischemia Clinical Parameters No allergies or sensitivity to given drug. ≥18 years Unaltered LOA Cardiac Ischemia Nitroglycerin: Prior nitroglycerin use and/or IV established HR 60 - 159 SBP ≥100. D/C if BP drops more than 1/3 of initial No phosphodiesterase inhibitor* in past 48 hrs No right ventricular MI ASA: Able to chew and swallow Prior use of ASA if asthmatic No allergy to ASA or NSAIDs No Current, active bleed No CVA / TBI in past 24 hrs Morphine: (after 3rd nitroglycerin or if nitroglycerin is contraindicated) No injury to Head / Torso / Pelvis SBP ≥100. D/C if BP drops more than 1/3 of initial Adult Dose ≥18 years only Drug Initital Dose Q Repeat Dose Max Nitroglycerin 0.4 mg S/L 5 min 0.4 mg 6 doses ASA 160 mg PO N/A N/A 160 mg Morphine 2 mg IV 5 min 2 mg 5 doses Notes: Perform 12 / 15 lead * Phosphodiesterase inhibitors: - Sidenafil: Viagra, Revatio (for pulmonary hypertension) - Tadalafil: Cialis, Adcirca (for pulmonary hypertension) - Vardenafil: Levitra, Staxyn For reference only 29 Central East Prehospital Care Program Notes: A 15 lead ECG should be obtained; • When a 12 lead shows an inferior wall MI • When there is ST depression in V1-V4 • When the 12 lead is normal but the patient is exhibiting signs or symptoms of cardiac ischemia V4R • • • The V4R lead is obtained by moving V4 to the same location but on the right chest wall. (5th intercostal space, mid clavicular line). V4R is considered anatomically contigous with II, III and AVF ST elevation in V4R indicates an infarct of the right ventricle. V8 and V9 • The V8 lead is obtained by moving V5 around to the posterior, left chest wall and placing it on the mid-scapular line just below the scapula. • The V9 lead is obtained by moving V6 around to the back and placing it between V5 and the vertebral column. • ST elevation in V8 and V9 indicates an infarct in the posterior wall of the left ventricle. • Infarcts in the posterior wall often show up as ST depression in leads V1-V4 12 lead versus anatomical region Lateral Left Septal Anterior Left Inferior Left Lateral Left Septal Lateral Left Inferior Left Inferior Left Anterior Left Lateral Left 30 Central East Prehospital Care Program For reference only STEMI Bypass Policy Indications Patient who is experiencing continuous cardiac ischemic "chest pain" or chest discomfort. STEMI Bypass Clinical Parameters • • • • • • • • ≥18 yrs Unaltered LOA SBP≥ 80 mmHg (with intervention if required) Secure airway, and able to ventilate Current episode is < 12 hours in duration 12 lead indicative of ST elevation MI, NO LBBB or ventricular paced rhythms No advanced directives indicating a restriction in care • • Call location is in York or Durham Region Patient contact to arrive the designated cath lab is < 60 min. If the pick up is in York and transporting to SRHC - call 905-895-4521 ext. 7777 If the pick up is in Durham and transporting to RVHS-C - call 416-287-8364 Central East Prehospital Care Program For reference only 31 COMMON IMITATORS OF MI’S INTERPRETING ST SEGMENT ’S IS NOT POSSIBLE IN THE FOLLOWING RYTHYMS (NOT A COMPLETE LIST – OTHER IMITATORS EXIST) LBBB Characterised by a supraventricular rhythm (identified by the presence of P waves) & a wide QRS complex. A LBBB will have a -ve terminal deflection in V1 and typically a secondary R wave in V6 (seen as a notched complex seen as RsR’ below). RBBB will have a +ve terminal deflection in V1 typically with a notched complex & a slurred or prolonged S wave in V6. VENTRICULAR PACED RHYTHM A pacer spike is typically seen immediately preceding the QRS complex which will be wide. LVH Look at the RS complex in either V1 or V2 and count the small boxes of the -ve deflection Then do the same with either V5 or V6, counting the small boxes of the +ve deflection Add the two numbers together, if they equal 35 mm’s then it’s likely LVH 32 Central East Prehospital Care Program For reference only Cardiogenic Shock Indications STEMI and Cardiogenic Shock. Clinical Parameters SBP < 90 Bolus: Clear Chest Dopamine: No allergy or sensitivity No tachydysrhythmias (excluding sinus tach) No mechanical shock state (i.e. Tension Pneumothorax, Pulmonary Embolism, Pericardial Tamponade) Cardiogenic Shock No pheochromocytoma Adult Doses (≥ 18 Years) Drug Initial Dose Q Repeat Dose Bolus IV/IO 10 ml/Kg Reassess q 250 ml N/A Dopamine IV 5 mcg/Kg/min 5 min Increase by 5 mcg/Kg/min Max 20 mcg/ Kg/min Pediatric Doses (< 18 years) Drug Initial Dose Q Repeat Dose Bolus IV/IO 10 ml/Kg Reassess q 100 ml N/A Dopamine IV 5 mcg/Kg/min 5 min Increase by 5 mcg/Kg/min Notes: Titrate Dopamine to SBP 90 - 110 mmHg. If discontinuing Dopamine electively, do so gradually over 5-10 minutes. Contact BHP if patient is bradycardic with respect to age. If bolus is contraindicated due to crackles, consider Dopamine. Max 20 mcg/ Kg/min Central East Prehospital Care Program For reference only 33 Dopamine Administration Buretrol Set-up: • • • • • Close both roller clamps Spike bag Open top roller clamp (between bag and Buretrol) Fill chamber with 100 cc Close top roller clamp OSCAR O-open bottom roller clamp S-squeeze drip chamber C-close bottom roller clamp And R-release drip chamber Prime the line as usual 34 Central East Prehospital Care Program For reference only Symptomatic Bradycardia Indications Bradycardia with Hemodynamic Instability Clinical Parameters Vital Sign Parameters Allergy or sensitivity to given drug HR < 50 with hemodynamic instability Atropine: No hypothermia No heart transplant Dopamine: No pheochromocytoma TCP: No hypothermia SBP < 90 Adult Doses ≥18 Years Bradycardia Drug Initital Dose Q Repeat Dose Max Atropine IV 0.5 mg 5 min 0.5 mg 2 doses Dopamine IV (patch) 5 mcg/Kg/min 5 min Increase by 5 mcg/Kg/min 20 mcg/Kg/ min Transcutaneous Pacing (patch) Notes: Atropine may be beneficial in the setting of sinus bradycardia, atrial fibrillation, first degree AV block, or second degree type I AV block. A single dose of Atropine should be considered for second degree type II or third degree blocks with fluid bolus while preparing for TCP or if there is a delay in implementing TCP or if TCP is unsuccessful. Titrate dopamine to achieve a SBP of 90-110 mmHg. For reference only 35 Central East Prehospital Care Program Dopamine Administration Buretrol Set-up: • • • • • Close both roller clamps Spike bag Open top roller clamp (between bag and Buretrol) Fill chamber with 100 cc Close top roller clamp OSCAR O-open bottom roller clamp S-squeeze drip chamber C-close bottom roller clamp And R-release drip chamber Prime the line as usual PACING • Attach limb leads • Attach large pads • Activate pacing function • Increase CURRENT (mA) until electrical capture is evident • Check output (BP) • Reduce RATE to 60 if BP adequate • Re-assess BP • Consider Midazolam / Morphine 36 Central East Prehospital Care Program For reference only Procedural Sedation Indications Post-intubation OR Transcutaneous Pacing Clinical Parameters • • • • ≥18 years old No allergies or sensitivity to midazolam SBP ≥ 100 Respiratory rate ≥ 8/min (unless intubated) Procedural Sedation Adult Doses Drug Initial Dose Midazolam IV 2.5 - 5.0 mg 0.5 - 1.0 ml Q 5 min Repeat 2.5 - 5.0 mg 0.5 - 1.0 ml Max 10 mg or 2 doses For reference only 37 Central East Prehospital Care Program Combative patient Indications Combative patient Clinical Parameters • • • • ≥ 18 years old No allergies or sensitivity to midazolam SBP ≥ 100 No reversible causes (i.e. Hypoglycemia, Hypoxia, Hypotension) Adult Doses Drug Initial Dose Midazolam IV/IM 2.5 - 5.0 mg 0.5 - 1.0 ml Q 5 min Repeat 2.5 - 5.0 mg 0.5 - 1.0 ml Max 10 mg 2 doses or Combative Patient PATCH to BHP to proceed with Midazolam if unable to assess the patient for normotension or reversible causes. 38 Central East Prehospital Care Program For reference only Tachydysrhythmia Indications Symptomatic Tachydysrhythmia Clinical Parameters No allergy or sensitivity to given drug Tachydysrhythmia Valsalva / Adenosine: • SBP ≥ 100, Unaltered LOA • Use for narrow complex, regular tachycardias ≥ 150 / minute. • Not for sinus tachycardia, a-fib or a-flutter Adenosine specific: • Not on dipyridamole (Persantine, Aggrenox) or carbamazepine (Tegretol) • No bronchoconstriction on exam Lidocaine (PATCH): • SBP ≥ 100, Unaltered LOA • Use for wide complex regular tachycardias ≥ 120 / minute Cardioversion (PATCH): • SBP < 90, altered LOA, ongoing chest pain, other signs of shock • Unstable tachycardia ≥ 120 (wide) ≥ 150 (narrow) Valsalva 2 x 10-20 seconds Adult Doses ≥ 18 years Drug Initital Dose Adenosine IV Q Repeat Dose Max PATCH if suspected SVT with aberrancy (wide complex) 6 mg 2 min 12 mg 2 doses Lidocaine IV (PATCH) 1.5 mg/Kg 10 min 0.75 mg/Kg 3 doses Cardioversion (PATCH) 100j, 200j, Max possible Notes: Administer cardioversion in accordance with patch orders. Above joule settings apply to patch failures. Central East Prehospital Care Program For reference only 39 Cardioversion: • Attach limb leads • Attach large pads • Cycle through leads and select the lead that shows the largest 'R' wave • Activate 'Synch' and ensure synch markers appear on the "R" waves (if visible) • Select ordered joule setting • Begin running printer (run lots of strip before and after cardioversion) • Double check resuscitation equipment is prepared • Clear patient and press-and-hold 'SHOCK' after cardioversion monitor will automatically default out of synch mode. 40 Central East Prehospital Care Program For reference only Seizure Indications Active generalized motor seizure Clinical Parameters • • • Unresponsive No allergy or sensitivity to Midazolam Not hypoglycemic Adult Doses ≥ 50 kg Seizure Drug Initital Dose Q Repeat Max Midazolam IV 5 mg 5 min 5 mg 2 doses Midazolam IM/IN/Buccal 10 mg 5 min 10 mg 2 doses Pediatric Doses Drug Initital Dose Midazolam IV Midazolam IM / IN / Buccal Q Repeat Dose Max 0.1 mg/kg 5.0 mg Max 5 min 0.1 mg/kg 5.0 mg Max 2 doses 0.2 mg/kg 10 mg Max 5 min 0.2 mg/kg 10 mg Max 2 doses Notes: Conditions such as cardiac arrest and hypoglycemia often present as seizure and should be considered by a paramedic. Central East Prehospital Care Program For reference only 41 Midazolam Reference IV Dosages Weights are based on: (Age x 2) + 10 for 1-10 years 11-14 years based on CDC data All volumes based on 5 mg/ml concentration IM / IN / Buccal Dosages (IN has 0.12 ml added) 42 Central East Prehospital Care Program For reference only Opioid Toxicity Indications Altered LOC and respiratory depression and suspected opioid overdose. Clinical Parameters • • • Respiratory rate < 10 No allergy or sensitivity to naloxone. No uncorrected hypoglycemia Adult Doses ≥ 18 years Drug Initital Dose Q Repeat Max Patch - Naloxone IV* up to 0.4 mg N/A N/A 1 dose Patch - Naloxone 0.8 mg N/A N/A 1 dose Opioid Toxicity IM/IN/SC Notes: *For IV route, titrate naloxone only to restore the patient's respiratory status. Reference Notes: Opioid Toxicity typically present with: - Decreased LOA - Slow Respirations - Pinpoint pupils Some Common Opioids: Morphine, MS contin, Statex, Hydromorphone Fentanyl Percocet, Percodan Oxycocet, Oxycontin Tylenol III Heroin Codeine Central East Prehospital Care Program For reference only 43 Electronic Control Device Probe Removal Indications Electronic control device probe(s) embedded in patient Clinical Parameters • • • ≥18 years old Unaltered LOA Probes not embedded; Above clavicles, In the nipple(s) or in the Genital area Remove probes Police may require preservation of the probe(s) for evidentiary purposes. This directive is for removal of ECD only and in no way constitute treat and release, normal principles of patient assessment and care apply. ECD Probe Removal Notes: 44 Central East Prehospital Care Program For reference only Hypoglycemia Indications Agitation or altered LOA or seizure or symptoms of stroke Clinical Parameters Vital Sign Parameters No allergy or sensitivity to given drug Hypoglycemia ≥ 2 yrs < 4.0 mmol < 2 yrs < 3.0 mmol Glucagon: No Pheochromocytoma Adult Doses Drug Initital Dose Q Repeat Max Dextrose IV ≥ 50 kg 25 g 10 min 25 g 2 doses Glucagon IM ≥ 25 kg 1 mg 20 min 1 mg 2 doses Q Repeat Max Pediatric Doses Drug Initial Dose Hypoglycemia < 30 Days Dextrose IV D10W ≥ 30 Days to < 2 years Dextrose IV D25W ≥ 2 years to < 50 Kg 2 ml/Kg 0.2 g/kg Max 5 g (50 ml) 2 ml/Kg 1 ml/Kg Dextrose IV Glucagon IM 0.5 mg < 25 Kg 2 ml/Kg 2 doses 0.2 g/kg Max 5 g (50 ml) 10 min 0.5 g/kg Max 10 g (40 ml) 0.5 g/kg Max 25 g (50 ml) D50W 10 min 2 ml/Kg 2 doses 0.5 g/kg Max 10 g (40 ml) 10 min 1 ml/Kg 2 doses 0.5 g/kg Max 25 g (50 ml) 20 min 0.5 mg 2 doses Notes: If the patient responds to dextrose or glucagon, he/she may receive oral glucose or other simple carbohydrates. If only mild signs or symptoms are exhibited, the patient may receive oral glucose or other simple carbohydrates instead of dextrose or glucagon. If a patient initiates an informed refusal of transport, a final set of vital signs including blood glucometry must be attempted. Central East Prehospital Care Program For reference only 45 Dextrose Reference 46 Central East Prehospital Care Program For reference only Nausea / Vomiting Indications Nausea OR Vomiting Clinical Parameters • • • Unaltered LOA No allergies or sensitivity to dimenhydrinate or other antihistamines Not overdosed on antihistamines, anticholinergics or tricyclic antidepressants Adult Doses Drug Dimenhydrinate IV/IM Initial Dose Q 50 mg ≥ 50 Kg Repeat N/A N/A Max 1 dose Nausea / Vomiting Pediatric Doses Drug Initital Dose Dimenhydrinate IV/IM 25 mg ≥ 25 - < 50 Kg (if < 25 Kg Patch) Q Repeat Dose N/A N/A Max 1 dose Notes: If giving IV dilute dimenhydrinate with 9 ml normal saline to a 50 mg in 10 ml solution. Central East Prehospital Care Program Antihistamines Actifed Astemazole (Hismanal) Azatdine (Zadine) Cetirizine (Zyrtec, Reactine) Chlorpheniramine (Chlor-Trimeton, chlortripalon) Clemastine Cyproheptadine (Periactin) Dexchlorpheniramine Desloratadine (Clarinex) Dimenhydrinate (Dramamine) Diphenhydramine (Benadryl) Fexofenadine (Allegra) Hydroxyzine (Atarax, Vistaril) Loratadine (Claritin, Alavert) Phenothiazines Promethazine (Phenergan) Piperzanes Terfenadine (Seldane) Tricyclic antidepressants (TCA) Amitriptyline (Elavil, Ednep, Vanatrip) Clomipramine (Anafranil) Desipramine (Norpramin), Doxepin (Sinequan, Adapin, Silenor) Nortriptyline (Aventyl, Pamelor), Protriptyline (Vivactil) Trimipramine (Surmontil) Anticholinergics Atropine Hyoscine Glycopyrrolate (Robinul) ipratropium bromide (Atrovent) oxybutinin (Ditropan, Lyrinel XL) oxitropium bromide (Oxivent) tiotropium (Spiriva) For reference only 47 48 Central East Prehospital Care Program For reference only Pain Indications Severe pain and; • Isolated hip or extremity fractures or dislocation or; • Major burns or; • Current history of cancer related pain or; • Renal colic with prior history or; • Acute musculoskeletal back strain or; • Ongoing transcutaneous pacing. Clinical Parameters No allergy or sensitivity to drug administered. ≥18 years SBP ≥ 100 No injury to the head or chest or abdomen or pelvis. No SBP drop by 1/3 or more of the initial reading Pain • • • • • Drug Initial Dose Morphine IV 2 - 5 mg Q Repeat 5 min 2 - 5 mg Max 4 doses Notes: For ease of administration and control, when using 10 mg/ml morphine, draw up the morphine with 9 ml of saline to achieve a 10 mg in 10 ml solution. Central East Prehospital Care Program For reference only 49 Special Events Directives Special event: a preplanned gathering with potentially large numbers and the Special Event Medical Directives have been preauthorized for use by the Medical Director 50 Central East Prehospital Care Program For reference only Headache (Special Events Only) Indications Uncomplicated headache conforming to the patient's usual pattern. Clinical Parameters • • > 18 years old Unaltered LOA • • • No allergy or sensitivity to acetaminophen No acetaminophen in the last 4 hours No signs or symptoms of intoxication Adult Doses Drug Acetaminophen PO Initial Dose 325 - 650 mg Q Repeat N/A None Max 1 dose Notes: Headache Release from care. Advise patient that if the problem persists or worsens that they should seek further medical attention. Central East Prehospital Care Program For reference only 51 Minor Abrasion (Special Events ONLY) Indications Minor abrasions Clinical Parameters • • Unaltered LOA No allergies or sensitivity to topical antiobiotics Notes: Advise patient that if the problem persists or worsens that they should seek further medical attention. Minor Abrasion 52 Central East Prehospital Care Program For reference only Minor Allergic Reaction (Special Events Only) Indications Signs consistent with minor allergic reaction. Clinical Parameters • • • ≥18 years old Unaltered LOA SBP ≥100 (and other vitals within normal limits) • • • • • No allergy or sensitivity to diphenhydramine No antihistamine or sedative use in the previous 4 hours No signs or symptoms of a moderate to severe allergic reaction No signs or symptoms of intoxication No wheezing Adult Doses Drug Minor Allergic Reaction Diphenhydramine PO Notes: Release from care. Initial Dose 50 mg Q Repeat N/A N/A Max 1 dose For reference only 53 Central East Prehospital Care Program Musculoskeletal Pain (Special Events Only) Indications Minor musculoskeletal pain. Clinical Parameters • • ≥18 years old Unaltered LOA • • • No allergy or sensitivity to acetaminophen No acetaminophen use in the last 4 hours No signs or symptoms of intoxication Adult Doses Drug Acetaminophen PO Initial Dose 325 - 650 mg Q Repeat N/A None Max 1 dose Notes: Advise patient that if the problem persists or worsens that they should seek further medical attention. Musculoskeletal Pain Release from care. 54 Central East Prehospital Care Program For reference only Central East Prehospital Care Program For reference only 55 ReferenceMaterials Stroke Prompt Card.............................! Rule of nines charts.............................! Field Trauma Triage.............................! ECG Basics.........................................! IM Injections........................................! End Tidal CO2.....................................! Overdose Levels.................................! Toxidromes..........................................! Phone Numbers..................................! Codes of Entry....................................! Pediatric References..........................! Medication References.......................! PCP Scope of Practice........................! ACP Scope of Practice........................! VSA Special Circumstances...............! 3 4 5 6 7 8-9 10 11 12 - 13 14 15 16 - 32 33 34 - 35 36 2 3 4 Burn Chart 'Rule of nines' 5 Field Trauma Triage Guidelines • spinal cord injury with paraplegia or quadriplegia; • penetrating injury to head, neck, trunk or groin; • amputation above wrist or ankle; • adult patients with a Glasgow Coma Scale less than or equal to 10; • If adult GCS is greater than 10, any two of the following: (1) any alteration in level of consciousness; (2) pulse rate less than 50 or greater than 120; (3) blood pressure less than 80 systolic (or absent radial pulse); (4) respiratory rate less than 10 or greater than 24. • Pediatric Trauma Score of less than or equal to 8; • paramedic’s judgement that the patient requires assessment and treatment at a lead trauma centre. 6 ECG BASICS NORMAL ECG PARAMETERS P wave Typically +ve QRS Complex <0.12 sec T wave May be –ve in V1 PR Interval 0.12 – 0.2 seconds ST Segment Compared to TP QT Interval < ½ the preceding RR interval RATE CALCULATION Choose a QRS complex that falls on the thick line and count to your right until you reach the next complex. Q WAVES Pathological: Sign of MI (new or old) > ¼ of accompanying R wave and/or > 0.04 sec (1 sm box) 2. Physiological Q waves: Normal Less then criteria above QRS Nomenclature 1. 1 2 7 Intra Muscular Injection Landmarking and Needle Selection Needle length: 1 - 1.5" for school-age children and older Do not use this site in children < 2 years old. Base of pictured triangle is 2 - 3 finger widths below the acromium process. The insertion site is in the middle of the triangle. ! Needle length: 5/8" for small infants 1" for young children 1.5" for school-age children and older The insertion site is in the middle of the depicted rectangle, anterolateral aspect of the middle of the thigh. ! 8 9 10 OVERDOSE LEVELS THIS CHART IS INTENDNED ONLY AS A GUIDE. NUMEROUS VARIABLES INFLUENCE TOXIC / LETHAL LEVELS. ASA Acetaminophen Amphetamines Atropine Benadryl (diphenhydramine) Barbiturates Benzodiazepines Cocaine (As most sreet drugs, impurities, etc make predicting toxic levels difficult) Codeine Demerol Digitalis Glycosides Dilantin GHB Ibuprofen Methadone Methamphetamine Morhpine Methanol Monoamine Oxidase Inhbitors (MAOI’s) Tricyclic Anti depressants (TCA’s) Valium (Diazepam) Adults & children: 300 – 500 mg/kg is a severe ingestion >500 mg/kg may be fatal Adults: 70 – 140 mg /kg may be toxic 140 mg/kg can be fatal Children: < 5 yr’s old 100 200 mg/kg may be toxic >200 mg/kg may be fatal 100 mg (40 mg in children) 100 mg 20 40 mg/kg may be fatal 1 – 3 gm Toxicity ranges from 500 – 1500 mg’s A rock is usually 100 – 200 mg A typical ‘line’ is usually 20 – 30 mg A spoon is usually 5 – 10 mg 2 – 25 mg/kg can cause toxic effects 500 – 1000 mg can be fatal 1 gm may be fatal Digitalis: 2 gm may be fatal Digitoxin: 3 mg may be fatal Digoxin: 10 mg may be fatal 20 mg/kg may be toxic 30 – 60 mg may be toxic Adults: 6 54 mg may be toxic Children: 200 – 400 mg/kg may be severe ingestion >400 mg/kg may be fatal 50 mg can be fatal 1 mg/kg may be fatal 200 – 250 mg ingestion can be fatal 30 – 240 ml may be fatal 2 – 3 mg/kg is life threatening 4 – 6 mg/kg is typically fatal 20 – 35 mg/kg may be severe 35 – 40 mg/kg may be fatal 1 gm may be fatal (TCA’S/BENADRYL /GRAVOL/ANTIHIST) Anticholinergic MARIJUANA INHALANTS (Depressant) GHB (Anaesthetic) KETAMINE (Opiate Narcotic) HEROIN (STIMULANT) COCAINE / CRACK (STIMULANT) METH (STIMULANT) ECSTASY TOXIDROME/ INFO Pills Plant material Alter + Alter + Alter Alter PO, SC, Alter Ø + + + LOA RR HR BP Smoked, Mixed Alter food, Tea Inhaled Snorted, IV, smoked, PO Drank (often mixed ETOH) Snorted, IV, smoked, SC Snorted, IV, smoked Snorted, IV, smoked, PO Diff coloured powder, Rock, Crystal Diff coloured powders, Rock, Crystal Light-Dark Powders or Black tarry substance Clear liquid, White powder Looks like water Glue, paint, petro, Aerosols PO HOW USED Looks like pills/candy APPEARANCE Arrhythmias Poss dilated Arrhythmias Arrhythmias TachyArrhythmias TachyArrhythmias Irregular Dilated Norm/Dilat Slugg MISC N, Warm, Wet, Possible seizures Sweaty, Tº, Nausea Nausea, Seizures, Slurred speech, Dizzy, Hallucinations Bloodshot eyes, ‘Munchies’ N/V, Restless, Seizures, CP, Prone to MI/CVA, Violent Tremors , Poss CVA, Seizures, Tº, Sweaty TachyTº, Teeth Arrhythmias grinding, Irrational EC G Norm/Dilat Slugg Const Dilated Poss dilated Dilated PUPILS 11 12 Phone Numbers ! 13 Phone Numbers ! 14 NOTES: 15 Pediatric Reference Age Respiratory Rate Heart Rate 0-3 months 3-6 months 6-12 months 1-3 years 6 years 10 years 30-60 30-60 25-45 20-30 16-24 14-20 90-180 80-160 80-140 75-130 70-110 60-90 < 2 Year Spontaneous To Speech To Pain None EYE OPENING 4 3 2 1 > 2 Year Spontaneous To Speech To Pain None BEST RESPONSE TO AUDITORY / VISUAL STIMULUS (0-2 years) BEST VERBAL RESPONSE (2-5 Years) Orients to sounds, follows objects, 5 smiles, coos, babbles Cries appropriately; when upset 4 Inappropriate, persistent cry / Scream Agitated / restless; grunts, Moans No Response < 2 Year 3 2 1 Oriented, appropriate words Confused, inappropriate words Inappropriate, persistent cry / scream Incomprehensible sounds; grunts No Response BEST MOTOR RESPONSE > 2 Year Spontaneous movements 6 Spontaneous movements Localizes pain 5 Localizes pain Withdraws from pain 4 Withdraws from pain Abnormal flexion (decorticate) 3 Abnormal flexion (decorticate) Abnormal extension (decerebrate) 2 Abnormal extension (decerebrate) No response 1 No response 16 ACETAMINOPHEN CLASS Analgesic ACTION Although not fully elucidated, believed to inhibit the synthesis of prostaglandins in the central nervous system and work peripherally to block pain impulse generation; produces antipyresis from inhibition of hypothalamic heatregulating center. ONSET < 1 hour HALF-LIFE ELIMINATION 2 hours (adults) METABOLISM PEAK EFFECT 10-60 minutes At normal therapeutic dosages, primarily hepatic metabolism to sulfate and glucuronide conjugates, while a small amount is metabolized by CYP2E1 to a highly reactive intermediate, N-acetyl-p-benzoquinone imine (NAPQI), which is conjugated rapidly with glutathione and inactivated to nontoxic cysteine and mercapturic acid conjugates. At toxic doses (as little as 4 g daily) glutathione conjugation becomes insufficient to meet the metabolic demand causing an increase in NAPQI concentrations, which may cause hepatic cell necrosis. Oral administration is subject to first pass metabolism. 17 ADENOSINE CLASS Antiarrhythmic ACTION Slows conduction time through the AV node, interrupting the re-entry pathways through the AV node, restoring normal sinus rhythm. Adenosine also causes coronary vasodilation and increases blood flow in normal coronary arteries with little to no increase in stenotic coronary arteries; thallium-201 uptake into the stenotic coronary arteries will be less than that of normal coronary arteries revealing areas of insufficient blood flow. ONSET Rapid HALF-LIFE ELIMINATION < 10 seconds METABOLISM DURATION Very brief Blood and tissue to inosine then to adenosine monophosphate (AMP) and hypoxanthine 18 ASPIRIN (ACETYLSALICYLIC ACID) CLASS Platelet aggregation inhibitor, analgesic, antipyretic and anti-inflammatory. ACTION Decreases clotting by inactivating cycloxygenase, interfering with Thromboxane A2 production within the platelets. Thromboxane A2 also causes arteries to constrict. Reduces morbidity/mortality in adult patients with CP from MI. ABSORPTION TIME TO PEAK Rapid 1-2 hours METABOLISM DURATION 4-6 hours Hydrolyzed to salicylate (active) by esterases in GI mucosa, red blood cells, synovial fluid, and blood; metabolism of salicylate occurs primarily by hepatic conjugation; metabolic pathways are saturable. COMMON NSAIDS (Not a complete list) OVER-THE-COUNTER PRESCRIPTION ¬ Aspirin ¬ Ibuprofen (Motrin) ¬ Ibuprofen (Motrin IB, Advil, Nuprin, Rufen) ¬ Indomethacin (Indocin) ¬ Tolmetin (Tolectin) ¬ Ketoprofen (Actron, Orudis KT) ¬ Ketoprofen (Orudis, Oruvail) ¬ Naproxen (Aleve) ¬ Naproxen (Naprosyn, Anaprox) ¬ Diclofenac (Voltaren, Cataflam, Solaraze) 19 ATROPINE CLASS Parasympatholytic, anticholinergic ACTION Blocks the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the CNS; increases cardiac output, dries secretions. Atropine reverses the muscarinic effects of cholinergic poisoning. The primary goal in cholinergic poisonings is reversal of bronchorrhea and bronchoconstriction. Atropine has no effect on the nicotinic receptors responsible for muscle weakness, fasciculations, and paralysis. ONSET Rapid HALF-LIFE ELIMINATION 2-3 hours METABOLISM Hepatic DISTRIBUTION Widely throughout the body; crosses placenta; trace amounts enter breast milk; crosses blood-brain barrier. 20 DEXTROSE 50% IN WATER CLASS Carbohydrate (Caloric Supplement) ACTION Replenishes blood glucose levels reversing hypoglycemia. METABOLISM Metabolized to carbon dioxide and water. 21 DIMENHYDRINATE (GRAVOL®) CLASS Antiemetic, Antihistamine ACTION Competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract; blocks chemoreceptor trigger zone, diminishes vestibular stimulation, and depresses labyrinthine function through its central anticholinergic activity. ONSET 1-5 minutes (IV) 15-30 minutes (oral) PEAK EFFECT 1-2 Hours DURATION 3-6 hour 22 DIPHENHYDRAMINE (BENADRYL®) CLASS Antihistamine ACTION Competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract; anticholinergic and sedative effects are also seen. ONSET PEAK EFFECT DURATION 1-5 minutes (IV) 1-2 hours (IV) 4-8 hours 1-3 hours (oral) 2-4 hours (oral) HALF-LIFE ELIMINATION 2-10 hours 23 DOPAMINE CLASS Sympathomimetic agent ACTION Stimulates both adrenergic and dopaminergic receptors, lower doses are mainly dopaminergic stimulating and produce renal and mesenteric vasodilation, higher doses also are both dopaminergic and beta1-adrenergic stimulating and produce cardiac stimulation and renal vasodilation; large doses stimulate alpha-adrenergic receptors. ONSET 5 minutes HALF-LIFE ELIMINATION 2 minutes METABOLISM DURATION <10 minutes Renal, hepatic and plasma, 75% to inactive metabolites by monoamine oxidase and 25% to norepinephrine. 24 EPINEPHRINE CLASS Sympathomimetic agent ACTION Stimulates alpha-, beta1-, and beta2-adrenergic receptors resulting in relaxation of smooth muscle of the bronchial tree, cardiac stimulation (increasing myocardial oxygen consumption), and dilation of skeletal muscle vasculature; small doses can cause vasodilation via beta2-vascular receptors; large doses may produce constriction of skeletal and vascular smooth muscle. ONSET 5-10 minutes (bronchodilation) METABOLISM Taken up into the adrenergic neuron and metabolized by monoamine oxidase and catechol-o-methyltransferase; circulating drug hepatically metabolized. 25 GLUCAGON CLASS Hyperglycemic agent ACTION Stimulates adenylate cyclase to produce increased cyclic AMP, which promotes hepatic glycogenolysis and gluconeogenesis, causing a raise in blood glucose levels. ONSET HALF-LIFE ELIMINATION 30 minutes (IM) 8-18 minutes DURATION 60-90 minutes (SQ) METABOLISM Primarily hepatic, some inactivation occurring renally and I the plasma. 26 LIDOCAINE (XYLOCAINE) CLASS Class Ib antiarrhythmic ACTION Suppresses automaticity of conduction tissue, by increasing electrical stimulation threshold of ventricle, HisPurkinje system, and spontaneous depolarization of the ventricles during diastole by a direct action on the tissues; blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions, which results in inhibition of depolarization with resultant blockade of conduction. ONSET DURATION 45-90 seconds 10-20 minutes METABOLISM 90% Hepatic 27 Xylometazoline (Baliminil) CLASS Sympathomimetic agent ACTION Xylometazoline nasal is a decongestant. A vasoconstrictor. The nasal formulation acts directly on the blood vessels in the nasal tissues. Constriction of the blood vessels in the nose and sinuses leads to a decrease in congestion. ONSET DURATION Rapid 10-20 minutes METABOLISM 90% Hepatic 28 MIDAZOLAM (VERSED) CLASS Benzodiazepine, CNS depressant, Sedative and Amnesic ACTION Binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron at several sites within the central nervous system, including the limbic system, reticular formation. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. This shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization. ONSET PEAK EFFECT DURATION 15 minutes (IM) 0.5 – 1 hour 6 hours (IM) 3-5 minutes (IV) 4-8 minutes (IN) 18-41 minutes (IN) METABOLISM Extensively hepatic HALF-LIFE ELIMINATION 2-6 hours 29 MORPHINE CLASS Opioid analgesic ACTION Binds to opiate receptors in the CNS, causing inhibition of ascending pain pathways, altering the perception of and response to pain; produces generalized CNS depression. ONSET PEAK EFFECT DURATION 2-5 minutes (IV) 20 minutes (IV) HALF-LIFE ELIMINATION 2-4 hours METABOLISM Hepatic 1 hour 30 NALOXONE (NARCAN) CLASS Narcotic Antagonist ACTION Competitive narcotic antagonist. Displaces any narcotics bound to opiate receptor sites reversing their effects. ONSET HALF-LIFE ELIMINATION 2-5 minutes (IM) 3-4 hours (neonates) 8-13 minutes (IN) 0.5-1.5 hours (adult) 2 minutes (IV) METABOLISM Primarily hepatic DISTRIBUTION Crosses placenta DURATION 30-120 minutes 31 NITROGLYCERIN CLASS Coronary vasodilator, smooth muscle relaxant and an anti-anginal. ACTION Produces a vasodilator effect on the peripheral veins and arteries with more prominent effects on the veins. Primarily reduces cardiac oxygen demand by decreasing preload (left ventricular end-diastolic pressure); may modestly reduce afterload; dilates coronary arteries and improves collateral flow to ischemic regions. In smooth muscle, nitric oxide activates guanylate cyclase which increases guanosine 3’5’ monophosphate (cGMP) leading to dephosphorylation of myosin light chains and smooth muscle relaxation. ONSET PEAK EFFECTS 1-3 min.(sl sprays and sl tablet) 15-30 min. (topical) 30 min.(transdermal) 5 min.(tablet) 4-10 min.(sl spray) 60 min.(topical) 120 min. (transdermal) DURATION 25 min. (sl spray and sl tablet) 7 hours (topical) 10-12 hours (transdermal) HALF-LIFE 1-4 minutes METABOLISM Extensive first-pass effect; metabolized hepatically to glycerol di- and mononitrate metabolites via liver reductase enzyme; subsequent metabolism to glycerol and organic nitrate; nonhepatic metabolism via red blood cells and vascular walls also occurs. 32 SALBUTAMOL (VENTOLIN) CLASS Sympathomimetic, Beta 2 agonist ACTION Relaxes bronchial smooth muscle by action on beta2receptors with little effect on heart rate. ONSET 10 minutes (nebulized/oral inhalation) HALF-LIFE ELIMINATION 3-8 hours (inhalation) METABOLISM Hepatic to an inactive sulfate DURATION 3-4 hours (nebulized/oral inhalation) 33 PCP Scope of Practice Perform the following skills: Ø Semi-Automated External Defibrillation Ø Manual defibrillation (when working with an ACP who has indicated that a shock and its energy setting is to be delivered) Ø Intravenous monitoring Ø Intravenous Access/Therapy for patients ≥ 2 years of age (if certified / authorized in autonomous IV) Ø Volume (crystalloid) Replacement Therapy for patients ≥ 2 years of age (if certified / authorized in autonomous IV) Ø Basic Airway management Ø Advanced Airway management with the King LT Ø Oro-pharyngeal Suctioning Ø Current CPR standards for Health-Care Providers Ø 3 lead monitoring and interpretation Ø 12 and 15 lead acquisition and interpretation Ø Administration of CPAP Ø Preparation of ACP pre-loaded medications Ø Assessments and Interpretation of findings ie chest sounds & tx Ø Capillary Blood Sampling & glucometer use Ø Utilization/interpretation of SpO2 Administer the following medications: Ø Ø Ø Ø Ø Ø Ø Ø ASA (PO) Dextrose: 50% solution (IV) (if certified / authorized in autonomous IV) Dimenhydrinate (IV/IM) (IV only if certified / authorized in autonomous IV) Diphenhydramine (IV/IM) (IV only if certified / authorized in autonomous IV) Epinephrine 1:1000 (IM/Inhalation) Glucagon (IM) Nitroglycerin spray (SL) Salbutamol MDI and nebulization (Inhalation) By the following routes: Ø Ø Ø Ø Ø ! Oral (PO) Sublingual (SL) Inhalation (nebulized or MDI) Intramuscular (IM) Intravenous (IV) (if certified / authorized in autonomous IV) 34 ACP Scope of Practice Perform the following skills: Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Ø Manual Defibrillation Synchronized Cardioversion Transcutaneous Pacing Intravenous Access/Therapy Intraosseous Access/Therapy Volume (crystalloid) Replacement Therapy Advanced Airway management with the King LT Oral Endotracheal Intubation Nasal Tracheal Intubation Difficult Airway with lighted stylet / Bougie Laryngoscopy ETT (Deep) Suctioning FBAO Removal (Magill Forceps) Needle Chest Decompression 3 lead monitoring and interpretation 12 and 15 lead acquisition and interpretation Assessments and Interpretation of findings ie chest sounds & tx Venous and Capillary Blood Sampling & glucometer use Utilization/interpretation of SpO2 and Endtidal CO2 monitoring Application of Continuous Positive Airway Pressure (CPAP) Administer the following medications: Ø Atropine (IV/ETT) Ø ASA (PO) Ø Dextrose: 50%, 25% or 10% solutions (IV/IO) Ø Dimenhydrinate (IV/IM) Ø Diphenhydramine (IV/IM) Ø Dopamine (IV drip) Ø Epinephrine 1:1000 (IV/IM/IO/ETT/Inhalation) Ø Epinephrine 1:10,000 (IV/ETT) Ø Glucagon (IM) Ø Lidocaine injectable (IV/ETT) Ø Lidocaine topical (Inhalation) Ø Midazolam (IV/IM/IN/Buccal) Ø Morphine (IV) Ø Naloxone (IV/IM/IN/SC) Ø Nitroglycerin spray (SL) Ø Xylometazoline (Inhalation) Ø Salbutamol MDI (Inhalation) ! 35 By the following routes: Ø Intravenous (IV) Ø Endotracheal (ETT) Ø Oral (PO) Ø Sublingual (SL) Ø Subcutaneous (SC) Ø Buccal (BU) Ø Inhalation (nebulized or MDI) Ø Intraosseous (IO) Ø Intramuscular (IM) Ø Intranasal (IN) Ø Topical 36 Vital Signs Absent Patient Here are some guidelines to help with the determination of the recognition of death and/or the termination of resuscitation when presented with a VSA: 1. Patient presenting as “Obviously Dead” a. Decapitation, transection, visible decomposition, putrefaction; or b. Absence of vital signs and: A grossly charred body; or • An open head or torso wounds with gross outpouring of cranial or visceral contents; or • Gross rigor mortis; or • Lividity • 2. Patient without vital signs and the subject of a Ministry of Health and Long-Term Care Do Not Resuscitate Confirmation Form. Consider honoring the DNR Confirmation Form. 3. Patient without vital signs and the subject of a “legal looking’ document or the old DNR Medical Directive and Funeral Home Transfer Form, consider calling the BHP to receive termination of resuscitation order. 4. Patient without vital signs and the subject of the possible application of the TOR Medical Directive (Medical or Trauma). Consider calling the BHP for termination of resuscitation order. In the event that a physician on scene is willing to assume care and responsibility of the patient, provide assistance as possible within your scope of practice. *Paramedics must carefully consider matters such as scene integrity, investigative issues, family concerns and disposition of body.