Ch. 17, Blood Exam due NLT Wed. July 15, 2015 Name___________________________________ MATCHING. Choose the item that best matches each item listed or in the illustrations. Figure 17.1 Using Figure 17.1, match the following: 1) Monocyte. 1) Answer: B 2) Lymphocyte. 2) Answer: D 3) Eosinophil. 3) Answer: C 4) Neutrophil. 4) Answer: A 5) Most common white blood cell found in whole blood. 5) Answer: A 6) Mounts an immune response by direct cell attack or via antibodies. 6) Answer: D 7) Kills parasitic worms. 7) Answer: C 8) Becomes a macrophage. 8) Answer: B 9) Main bacteria killer during acute infections. 9) Answer: A 1 MATCHING. Choose the item in column 2 that best matches each item in column 1. Match the following: 10) Nucleus has two lobes; contains granules of lysosomal enzymes; functions in attacking parasitic worms. Answer: B 11) Nucleus is multilobed; functions as a phagocyte; contains fine indistinct granules. Answer: A A) Neutrophil 10) B) Eosinophil C) Basophil D) Erythrocyte 11) E) Monocyte 12) Transports CO2 and oxygen. 12) Answer: D 13) Contains a U- or an S-shaped nucleus; granules stain very dark; releases histamine and heparin. 13) Answer: C 14) Largest of the WBCs; crucial in defense against viruses; associated with chronic infections. 14) Answer: E Match the following: 15) The major contributor to plasma osmotic pressure. Answer: B A) Fibrinogen 15) B) Albumin 16) Thrombin catalyzes the activation of these molecules present in plasma. 16) Answer: A 17) Forms the structural framework of a blood clot. 17) Answer: A 18) Makes up most of plasma protein. 18) Answer: B 2 Match the following: 19) Main contributor to osmotic pressure. Answer: A 20) Antibodies released by plasma cells during immune response. Answer: C A) Albumin 19) B) Alpha and beta globulins C) Gamma globulins 20) D) Fibrinogen 21) Forms fibrin thread of blood clot. 21) Answer: D 22) Transport proteins that bind to lipids, metal ions, and fat-soluble vitamins. 22) Answer: B Match the following: 23) Polymorphonuclear leukocyte. A) Hemoglobin 23) Answer: E B) Monocyte 24) White blood cell with dark-staining nucleus. 24) C) Factor VIII Answer: B 25) Protein capable of changing shape and color in the presence of O 2 . Answer: A D) Agglutination 25) E) Neutrophil 26) Adverse reaction of donor blood cells with recipient plasma. 26) Answer: D 27) Lacking in hemophilia type A. 27) Answer: C Match the following: 28) Produced by platelets. Answer: A 29) A fibrous protein that gives shape to an RBC plasma membrane. A) Prostaglandin derivates such as Thrombozane A2 28) B) Spectrin 29) Answer: B 3 30) Hormone that stimulates production of RBCs. Answer: B 31) Stimulates WBC production. A) Interleukins and CSFs 30) B) Erythropoietin 31) C) Heparin Answer: A 32) Natural anticoagulant found in basophils. 32) Answer: C MATCHING. Choose the item that best matches each item listed or in the illustrations. Figure 17.2 Using Figure 17.2, match the following: 33) Type O. 33) Answer: D 34) Type A. 34) Answer: B 35) Type AB. 35) Answer: A 36) Type B. 36) Answer: C 4 37) Universal donor. 37) Answer: D 38) Universal recipient. 38) Answer: A MATCHING. Choose the item in column 2 that best matches each item in column 1. Match the following: 39) Cancerous condition involving white blood cells. Answer: D A) Polycythemia 39) B) Embolism 40) Condition in which blood has abnormally low oxygen-carrying capacity. Answer: C C) Anemia 40) D) Leukemia 41) Abnormal excess of erythrocytes resulting in an increase in blood viscosity. 41) Answer: A 42) Free-floating thrombus in the bloodstream. 42) Answer: B TRUE/FALSE. Write 'T' if the statement is true and 'F' if the statement is false. 43) The primary source of RBCs in the adult human being is the bone marrow in the shafts of the long bones. Answer: True False 44) Leukemia refers to cancerous conditions of white blood cells. Answer: True True True True 46) False 47) The RBC "graveyard" is the liver. Answer: 45) False 46) The process of fibrinolysis disposes of bacteria when healing has occurred. Answer: 44) False 45) The immediate response to blood vessel injury is clotting. Answer: 43) 47) False 5 48) Hemorrhagic anemias result from blood loss. Answer: True 48) False 49) White blood cells are produced through the action of colony-stimulating factors. Answer: True False 50) Hemoglobin is made up of the protein heme and the red pigment globin. Answer: True True True True True True True True True True True True 60) False 61) All lymphocytes are leukocytes, but not all leukocytes are lymphocytes. Answer: 59) False 60) Granulocytes called neutrophils are phagocytic and are the most numerous of all white blood cell types. Answer: 58) False 59) Leukocytes move through the circulatory system by amoeboid motion. Answer: 57) False 58) A person with type B blood could receive blood from a person with either type B or type O blood. Answer: 56) False 57) Leukopenia is an abnormally low number of leukocytes. Answer: 55) False 56) Basophils increase in number when parasitic invasion occurs. Answer: 54) False 55) A condition of leukocytosis indicates over 11,000 white blood cells per cubic millimeter in the blood. Answer: 53) False 54) Positive chemotaxis is a feedback system that signals leukocyte migration into damaged areas. Answer: 52) False 53) Diapedesis is the process by which red blood cells move into tissue spaces from the interior of blood capillaries. Answer: 51) False 52) Each hemoglobin molecule can transport two molecules of oxygen. Answer: 50) False 51) Each heme contains an atom of iron and can transport one molecule of oxygen. Answer: 49) False 6 61) 62) Myelocytic leukemia involves a cancerous condition of lymphocytes. Answer: True 62) False MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. 63) Which of the following is a pivotal molecule associated with the external surfaces of aggregated platelets and is involved in the intrinsic and extrinsic mechanisms of blood clotting? A) Thrombin B) PGI2 63) C) Thromboplastin (prothrombin activator) D) PF3 Answer: D 64) What is the average normal pH range of blood? A) 4.65 4.75 B) 7.35 7.45 64) C) 8.35 8.45 D) 7.75 7.85 Answer: B 65) The special type of hemoglobin present in fetal red blood cells is ________. A) hemoglobin B B) hemoglobin F C) hemoglobin A D) hemoglobin S 65) Answer: B 66) Which of the choices below is the parent cell for all formed elements of blood? A) pluripotent stem cell (hemocytoblast) B) megakaryocyte C) polymorphonuclear cell D) NK cell 66) Answer: A 67) Which blood type is called the universal donor? A) B B) A B 67) C) A D) O Answer: D 68) Which of the following is a regulatory function of blood? A) prevention of blood loss B) maintenance of normal pH in body tissues C) transport of metabolic wastes from cells D) delivery of oxygen to body cells 68) Answer: B 69) Which of the following is a protective function of blood? A) maintenance of normal pH in body tissue B) maintenance of body temperature C) prevention of blood loss D) maintenance of adequate fluid volume Answer: B 7 69) 70) Which of the statements below is an incorrect or false statement? A) Unique to the ABO blood group is the presence in the plasma of preformed antibodies. B) Blood typing for the Kell, Lewis, and Duffy factors is always done before a blood transfusion. C) When a transfusion reaction occurs, the oxygen-carrying capacity of the transfused blood cells is disrupted and the clumping of RBCs in small vessels hinders blood flow to tissues beyond those points. D) Transfusion of incompatible blood can be fatal. 70) Answer: D 71) Which of the following might trigger erythropoiesis? A) hypoxia of EPO-producing cells B) moving to a lower altitude C) an increased number of RBCs D) decreased tissue demand for oxygen 71) Answer: A 72) As red blood cells age ________. A) membranes "wear out" and the cells become damaged B) they will eventually be excreted by the digestive system C) ATP production increases D) iron will be excreted by the kidneys 72) Answer: A 73) An individual who is blood type AB negative can ________. A) receive types A, B, and AB, but not type O B) donate to types A, B, and AB, but not to type O C) donate to all blood types in moderate amounts D) receive any blood type in moderate amounts except that with the Rh antigen 73) Answer: D 74) The most abundant plasma protein is ________. A) clotting protein B) albumin 74) C) bile D) globulin Answer: B 75) When neither anti-A sera nor anti-B sera clot on a blood plate with donor blood, the blood is type ________. A) A B) O C) A B D) B 75) Answer: B 76) Select the correct statement regarding blood cell formation. A) The main sites of blood cell production in adults are the spleen and the liver. B) Before the seventh month of fetal development, yellow marrow is the main site of blood cell formation. C) Yellow marrow is the main site of leukocyte formation. D) Red marrow is the main site of blood cell formation throughout adult life. 76) Answer: D 77) Blood volume restorers include all of the following except ________. A) saline solutions B) albumin C) packed cells Answer: C 8 77) D) dextran 78) James has a hemoglobin measurement of 16 g/100 ml blood. This is ________. A) abnormally low B) normal only if James is an infant C) above normal D) within the normal range 78) Answer: D 79) Which of these is not a normal plasma protein? A) albumin C) fibrinogen 79) B) thromboplastin D) gamma globulin Answer: B 80) All of the following can be expected with polycythemia except ________. A) increased blood volume B) high hematocrit C) high blood pressure D) low blood viscosity 80) Answer: D 81) No visible cytoplasmic granules are present in ________. A) basophils B) eosinophils C) monocytes 81) D) neutrophils Answer: C 82) Which of the following is not a phase of hemostasis? A) vascular spasm B) coagulation C) platelet plug formation D) fibrinolysis 82) Answer: D 83) Place the following in correct developmental sequence: 1. 2. 3. 4. 83) reticulocyte proerythroblast normoblast late erythroblast A) 1, 2, 3, 4 B) 2, 4, 3, 1 C) 2, 1, 3, 4 D) 1, 3, 2, 4 Answer: B 84) A lack of intrinsic factor, leading to a deficiency of vitamin B12 and large pale cells called macrocytes, is characteristic of ________. A) polycythemia C) aplastic anemia 84) B) sickle-cell anemia D) pernicious anemia Answer: D 85) The slowest step in the clotting process is ________. A) binding fibrin strands B) production of fibrin strands C) release of PF3 D) formation of prothrombin activator Answer: D 9 85) 86) Thromboembolic disorders ________. A) include embolus formation, a clot moving within the circulatory system B) include thrombus formation, a clot in a broken blood vessel C) result in uncontrolled bleeding D) are caused by vitamin K deficiency 86) Answer: A 87) Which of the following is not a cause of bleeding disorders? A) vitamin K deficiency B) thrombocytopenia, a condition of decreased circulating platelets C) a defect in the clotting cascade D) excess secretion of platelet-derived growth factor (PDGF) 87) Answer: D 88) Which of the following is characteristic of all leukocytes? A) They are nucleated. B) They have cytoplasmic granules. C) They are the most numerous of the formed elements in blood. D) They are phagocytic. 88) Answer: A 89) Which of the following is true about blood plasma? A) It is about 90% water. B) The main protein component is hemoglobin. C) It contains about 20 dissolved components. D) It is the same as serum but without the clotting proteins. 89) Answer: A 90) Platelets ________. A) have a life span of about 120 days B) stick to the damaged area of a blood vessel and help seal the break C) are the precursors of leukocytes D) have multiple nuclei 90) Answer: B 91) Which sequence is correct for the following events? 1. 2. 3. 4. 91) fibrinogen fibrin clot retraction formation of thromboplastin prothrombin thrombin A) 1, 2, 3, 4 B) 3, 4, 1, 2 C) 3, 2, 1, 4 Answer: B 10 D) 4, 3, 1, 2 92) Fred's blood was determined to be AB positive. What does this mean? A) His blood lacks Rh factor. B) There are no antibodies to A, to B, or to Rh antigens in the plasma. C) Antibodies to A and B are present in the red cells. D) He can only receive blood from a donor who is AB positive. 92) Answer: B 93) Sickling of red blood cells can be produced in those with sickle-cell anemia by ________. A) vigorous exercise B) travel at high altitude and vigorous exercise C) travel at high altitude D) malaria and travel at high altitude 93) Answer: B 94) All of the following conditions impair coagulation except ________. A) vascular spasm B) severe hypocalcemia C) vitamin K deficiency D) liver disease 94) Answer: A 95) When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother? A) if the father is RhB) if the child is Rh+ C) if the child is type O positive D) if the father is Rh+ 95) Answer: A 96) Complications of aplastic anemia generally do not include ________. A) suppressed immunity B) bleeding disorders C) impaired formation of all formed elements D) increase of leukocytes as a result of erythrocyte loss 96) Answer: D 97) Blood is a ________. A) colloid C) heterogeneous compound 97) B) suspension D) homogeneous compound Answer: B 98) What organ in the body regulates erythrocyte production? A) pancreas B) kidney C) brain 98) D) liver Answer: B 99) Which of the following chemicals does not help regulate blood pressure? A) ADH B) nitric acid C) atrial natriuretic peptide D) angiotensin II Answer: B 11 99) 100) Which statement best describes arteries? A) All contain valves to prevent the backflow of blood. B) Only large arteries are lined with endothelium. C) All carry blood away from the heart. D) All carry oxygenated blood to the heart. Answer: C 12 100)