Bios 325 ‐ Vertebrate Embryology Lecture Syllabus Spring 2015 Lecture: Tues, Thurs 11:00am – 12:15pm, Lecture Center C, Room C1 Instructors: Jennifer Schmidt, MBRB 4202, 312‐996‐5655, jvs@uic.edu Andrea McGinley, SELE 3083, 312‐995‐6284, amario3@uic.edu Website: All course materials will be available on Blackboard! The Blackboard site will be an important resource for class and exam schedules, reading assignments from the lecture and lab texts, and supplementary readings we will post from the Gilbert text as PDF files. Texts and Additional Resources: Lecture text: Human Embryology & Developmental Biology by Bruce M. Carlson (5th edition) ‐ Recommended Used copies of the 4th edition are available online, and will contain much of the same material. Supplemental lecture text: Developmental Biology by Scott Gilbert (9th edition or earlier) ‐ Optional Laboratory text: A Photographic Atlas of Developmental Biology by Shirley J. Wright ‐ Required (Note that this "text" is sold as loose pages intended to be put in a binder.) Used copies are available online. **NOTE: This course will rely heavily on lecture notes, class attendance is STRONGLY encouraged! Assigned readings from the Carlson and Gilbert texts are meant ONLY to supplement the lecture notes. Exams will be based on material covered in lecture, and you will be responsible for all lecture material. Class Date Topic Instructor Week 1 1‐13‐15 Mitosis/meiosis, cell cycle, mol bio review Schmidt 1‐15‐15 Spermatogenesis Schmidt Week 2 1‐20‐15 Reproductive hormones, menstrual cycle Schmidt 1‐22‐15 Oogenesis Schmidt Week 3 1‐27‐15 Contraception and fertilization Schmidt 1‐29‐15 Early frog development Schmidt Week 4 2‐3‐15 Early chick development Schmidt 2‐5‐15 Lab techniques McGinley Week 5 2‐10‐15 Early mammalian development Schmidt 2‐12‐15 Early mammalian development Schmidt (End of material for Exam 1) Week 6 2‐17‐15 Neurulation & somitogenesis Schmidt 2‐19‐15 Exam 1 Schmidt Week 7 2‐24‐15 Development of extraembryonic tissues Schmidt 2‐26‐15 X inactivation and genomic imprinting Schmidt Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 3‐3‐15 3‐5‐15 3‐10‐15 3‐12‐15 Human development video Stem cells and cloning Schmidt Schmidt McGinley McGinley 3‐17‐15 3‐19‐15 Development of the nervous system Development of the respiratory system (End of material for Exam 2) McGinley McGinley 3‐24‐15 3‐26‐15 Spring break Spring break 3‐31‐15 4‐2‐15 Development of the circulatory system Exam 2 McGinley McGinley 4‐7‐15 4‐9‐15 Development of the circulatory system Abnormal heart development McGinley McGinley 4‐14‐15 4‐16‐15 Development of the urinary system Development of the urinary system McGinley McGinley 4‐21‐15 4‐23‐15 Development of the reproductive system Development of the reproductive system McGinley McGinley 4‐28‐15 4‐30‐15 Development of the digestive system Development of the digestive system McGinley McGinley Embryonic folding Development of the nervous system 5‐4‐15** Final Exam McGinley **Final exam dates are set by the college, and therefore this date is tentative. The last few years the exam has been on Monday, but we cannot guarantee it will be again. We will let you know the official date as soon as exam schedules are announced. Bios 325 ‐ Vertebrate Embryology Lab Syllabus ‐ Spring 2015 Lab Room ‐ 3060 SEL LAB 2 3 4 5 6 7 DATE (1‐12‐15 and 1‐13‐15) (1‐14‐15 and 1‐15‐15) (1‐19‐15 and 1‐20‐15) (1‐21‐15 and 1‐22‐15) (1‐26‐15 and 1‐27‐15) (1‐28‐15 and 1‐29‐15) (2‐2‐15 and 2‐3‐15) (2‐4‐15 and 2‐5‐15) (2‐9‐15 and 2‐10‐15) (2‐11‐15 and 2‐12‐15) 8 9 10 11 12 13 14 15 16 (2‐16‐15 and 2‐17‐15) (2‐18‐15 and 2‐19‐15) (2‐23‐15 and 2‐24‐15) (2‐25‐15 and 2‐26‐15) (3‐2‐15 and 3‐3‐15) (3‐4‐15 and 3‐5‐15) (3‐9‐15 and 3‐10‐15) (3‐11‐15 and 3‐12‐15) (3‐16‐15 and 3‐17‐15) (3‐18‐15 and 3‐19‐15) 17 18 19 20 21 22 23 24 25 (3‐23‐15 thru 3‐26‐15) (3‐30‐15 and 3‐31‐15) (4‐1‐15 and 4‐2‐15) (4‐6‐15 and 4‐7‐15) (4‐8‐15 and 4‐9‐15) (4‐13‐15 and 4‐14‐15) (4‐15‐15 and 4‐16‐15) (4‐20‐15 and 4‐21‐15) (4‐22‐14 and 4‐23‐15) (4‐27‐15 and 4‐28‐15) (4‐29‐15 and 4‐30‐15) 1 TOPIC TEXT PAGES No Lab Introduction and Spermatogenesis p. 9‐16, 17‐21, 28‐38 No Lab ‐ Martin Luther King Holiday Spermatogenesis/Oogenesis p. 39‐41, 46‐52 Oogenesis/Early frog development p. 67‐71, 77‐80, 87‐88, 95‐96 Early frog development p. 105‐106, 109‐115 33 hour chick p. 129‐142, 171‐183, 186‐191 33 hour chick p. 129‐142, 171‐183, 186‐191 33 hour chick and review p. 129‐142, 171‐183, 186‐191 Exam 1 (W 11:00 section exam will be at 12:00) (Th 9:00 section exam will be at 10:00) 24 hour chick p. 116‐123, 129‐142, 171‐183 24 hour chick p. 116‐123, 129‐142, 171‐183 48 hour chick p. 129‐142, 171‐183, 194‐199 48 hour chick p. 129‐142, 171‐183, 194‐199 48 hour chick p. 129‐142, 171‐183, 194‐199 48 hour chick p. 129‐142, 171‐183, 194‐199 72 hour chick p. 129‐142, 171‐183, 201‐209 72 hour chick p. 129‐142, 171‐183, 201‐209 72 hour chick and review p. 129‐142, 171‐183, 201‐209 Exam 2 (W 11:00 section exam will be at 12:00) (Th 9:00 section exam will be at 10:00) Spring Break 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 10‐mm pig p. 227‐241, 251‐265 Review Exam 3 (W 11:00 section exam will be at 12:00) (Th 9:00 section exam will be at 10:00) Laboratory text: Laboratory text: Photographic Atlas of Developmental Biology by Shirley J. Wright (This text comes as loose pages for you to put in your own binder. I would suggest doing so from the beginning of class; we do not have extra pages to give out if they get lost.) Student responsibilities: There are many slides to look at and many terms to learn for this course. On Blackboard you will find term lists that list all the structures you should know and be able to identify. These sheets will help you focus on the most relevant material. A wise student would go beyond the limited material, and be familiar with all of the major terms in the assigned sections of the lab manual. Please DO NOT underestimate the amount of lab time required to become proficient with the course material. There is no substitute for time spent looking through the microscope, if you neglect the lab material early in the semester it will be nearly impossible to catch up. Lab Grading: The total value of laboratory credit is 150 points out of a course total of 450 points, or 33% of your final course grade. You MUST do well in lab to do well in the course. There are three laboratory exams in which you will be asked to identify a series of structures under the microscope. Each lab exam will be worth 50 points, and will consist of 25 identifications for 2 points each. Note: If you are having trouble in lab, please see the instructor or your TA as early as possible. Everyone associated with this course wants to help you succeed. We cannot help if you don’t ask, however, and waiting until AFTER you have failed exams makes it very difficult to pull your grade up.