TRINITY WESTERN UNIVERSITY BIOL333 INTRODUCTION TO MEDICAL MICRBIOLOGY (3 SEM. HRS.) SUMMER 2014 Instructor: Office: Office Hours Anthony Siame NEU 105B F 10:00 AM -2:00 PM Lectures: MTWR 8:30-11:30 Labs: MTWR 13:00-16:00 NEU 114 PREREQUISITES: BIOL 113/114 or BIOL 241/242 COURSE DESCRIPTION A study of pathogenic microorganisms and the control of infectious diseases. Topics include (i) the biology of bacteria, viruses, fungi, protozoa, and helminths; (ii) infectious diseases of temperate and tropical climates; (iii) immunity, immunology, and immunization; (iv) sterilization, disinfection, chemotherapeutic agents; and (v) epidemiology and public health microbiology. COURSE OBJECTIVES The course consists of lectures and laboratories. The laboratory component focuses on the biology of the medically-important microorganisms and clinical (diagnostic) microbiology using traditional cultivation methods, serology (ELISA,) and molecular biology. Students will: 1. 2. 3. 4. 5. 6. Develop an understanding of the major subject areas within medical microbiology Develop a vocabulary of microbiology terms and concepts with accuracy in their expression. Know the major infectious diseases of temperate and tropical climates. Know how to approach the study of infectious diseases in individuals and populations, know the signs and symptoms of major infectious diseases, the biology of causative agents, and methods of prevention and treatment. Understand major challenges in contemporary medical microbiology including emergence of new infectious diseases, development of antibiotic resistance, and bioterrorism. Get a hands-on approach to laboratory medical microbiology techniques for the safe handling, isolation, observation, identification, and disposal of pathogenic microorganisms. REQUIRED TEXTBOOKS 1. Microbiology: An Introduction, 11th Edition. 2013. Tortora, G. J., Funke, B. R., and Chase, C. R. THE BENJAMIN/CUMMINS PUBLISHING COMPANY. (The 10th Edition is still good) 2. Introduction to Laboratory Microbiology: Theory, Techniques, & Experiments. 2011. TRINITY WESTERN UNIVERSITY. RECOMMENDED: 1. Study Guide: Microbiology: An Introduction, 11th Edition. 2013. Funke, B. R. THE BENJAMIN/CUMMINS PUBLISHING COMPANY. (10th Edition is still good) COURSE MATERIAL Lecture outlines will be posted on MyCourses prior to each lecture. Follow the links under MyBIOL333 Notes. Outlines can be printed and brought to class and should be viewed as a starting point for the day's material. Students are responsible for material presented orally in class and for other in-class activities. The text book gives a more complete coverage of each topic. Note that we will be covering a lot of material each day (at least three chapters per day). Read the chapters before coming to class. We will work on some of the questions at the end of each chapter in class; come prepared. The study guide will be especially useful! 1 COMPONENTS OF FINAL GRADE Laboratory* and In-Class Exercises Attendance, Laboratory Reports, Mystery Guests, What is bugging you? (15%) One Final Laboratory Examination; Thursday, May 15th (25%) In-Class Exercises One Mid-Term Examination; Friday, May 9th (20%) Final Examination; Friday, May 16th TOTAL 40% 10% 20% 30% 100% *A student needs 50% in the laboratory component in order to pass the course. In accordance with FNAS laboratory policy, a student who misses one laboratory period, without an acceptable reason, loses credit for that laboratory. A student who misses two laboratory periods without acceptable reasons fails the laboratory component and the course. GRADING PROCEDURE This course employs the official TWU grading system; the percentage equivalents for letter grades are as follows: A+ A A- 90 -100% 85 - 89% 80 - 84% B+ B B- 77 - 79% 73 - 76% 70 - 72% COURSE TOPICS We will cover the following topics: Topics Introduction to Pathogenic Microorganisms Study of Pathogenic Microorganism Microbial Growth Physical and Chemical Control Introduction to Bacteria Introduction to Eukaryotes Viruses Epidemiology Infection and Disease Non-specific Host defence Specific Host Defence-Humoral & Cellular Immunity Applications of Immunology & Immune Disorders Immune Disorders Antimicrobial Agents Skin Infections Nervous System Infections Cardiovascular & Lymphatic Systems Infections Respiratory System Infections Digestive System Infections Reproductive & Urinary Systems Infections C+ C C- 67 - 69% 63 - 66% 60 - 62% D+ D DF 57 - 59% 53 - 56% 50 - 52% Below 50% Required Reading (Tortora) 1 3,4, 10 6 7 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 LATE ASSIGNMENTS POLICY Late assignments will be docked 5% per day until submitted. ACADEMIC INTEGRITY AND AVOIDING PLAGIARISM AT TWU As Christian scholars pursuing higher education, academic integrity is a core value of the entire TWU community. Students are invited into this scholarly culture and required to abide by the principles of sound academic scholarship at TWU. This includes, but is not limited to, avoiding all forms of plagiarism and cheating in scholarly work. TWU has a strict policy on plagiarism (see academic calendar, pp. 37-38). Learning what constitutes plagiarism and avoiding it is the student's responsibility. An excellent resource describing plagiarism and how to avoid it has been prepared by TWU Librarian William Badke and is freely available for download 2 (PPT file) or used as flash (self running) tutorials of varying lengths from: http://www.acts.twu.ca/lbr/plagiarism.ppt http://www.acts.twu.ca/lbr/Plagiarism.swf (14 minute flash tutorial) http://www.acts.twu.ca/lbr/Plagiarism_Short.swf (8 minute flash tutorial) STUDENTS WITH DISABILITIES Students with disabilities need to provide documentation to the Equity of Access Office, arrange specific accommodations with the Academic Disability Liaison, and identify themselves to professors. These steps should be taken in the first two weeks of classes. Students who neglect these actions may reduce the University’s ability to provide the accommodations in a timely manner. Please contact the Equity of Access Office (ext. 3404). 3