IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 1 Cells and Cell Processes Nutrition Recommended Prior Knowledge Students can come to this Unit with very little prior knowledge. In order to understand diffusion and osmosis, they will need some understanding of particle theory. Some knowledge of catalysts will also be helpful, and they should know a little about simple chemical reactions and how to represent these by word equations. The concept of pH should also be understood at a simple level. Context This Unit covers some fundamental topics that will be drawn on in all the Units that follow, and therefore the majority of it is covered by both Core and Extension candidates. Outline The Unit first considers the special features that make living things different from non-living objects, and then looks at the structure and functions of animal and plant cells, which leads into the organisation of cells into tissues. Some particular examples of specialised cells are considered, which introduces the idea of structural adaptations for particular functions. Movement of substances within living organisms by diffusion, osmosis and active transport (the latter for extension candidates only) is considered. A simple treatment of enzyme function and some applications completes the Unit. Note that section I, parts 2 and 3, are not included here, but have been placed in Unit 9. However, some teachers may prefer to cover these topics in this unit. I1 II 1 II 1 Learning Outcomes List and describe the characteristics of living organisms Define the terms nutrition, excretion, respiration, sensitivity, reproduction, growth and movement Identify and describe the structure of a plant cell (palisade cell) and an animal cell (liver cell) as seen under a light microscope Describe the differences in structure between typical plant and animal cells Relate the structures seen under the light microscope in the plant cell and the animal cell to their functions. Suggested Teaching Activities Ask students to suggest characteristics that are shared by plants and themselves but not by non-living objects. Palisade cells can be seen using prepared slides or transparencies of leaf sections. Freshwater filamentous algae can be mounted in a drop of water on a slide and viewed with a microscope. Liver cells are difficult to observe, but it may be possible to make temporary mounts of stained cheek cells. Extension candidates should consider functions of features that are common to plant and animal cells, and those that are found in plant cells only. They should consider how the differences between animal and plant cells relate to their different methods of obtaining nutrients. Online Resources Illustrations of cells http://www.cellsalive.com/ Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 2 II 3 II 4.1 Learning Outcomes Define tissue and relate the structure of the following to their functions: Ciliated cells – in respiratory tract Root hair cells – absorption Xylem vessels – conduction and support Muscle cells – contraction Red blood cells – transport Define organs and organ systems as illustrated by examples covered in Sections II and III Calculate the magnification and size of biological specimens using millimetres as units Define diffusion as the movement of molecules from a region of their higher concentration to a region of their lower concentration down a concentration gradient. Describe the importance of gaseous and solute diffusion and of water as a solvent. Suggested Teaching Activities Examine a temporary mount of epidermal tissue peeled from the inner surface of an onion bulb. The coverage of these examples of cells and of organs and organ systems could come later when they can be dealt with in context. Online Resources Examples of differentiated cells: http://www.iacr.bbsrc.ac.uk/n otebook/courses/guide/organ .htm Use the temporary mount of epidermal tissue peeled from the inner surface of an onion bulb and appropriate scale to determine the size of cells. Microscope magnification specifications & field of view http://www.microscopemicroscope.org/advanced/m agnification-1.htm Use a simple demonstration of diffusion, for example a potassium manganate IV crystal in a gas jar of water (diffusion of a solute), or ammonia and hydrochloric acid placed at opposite ends of a long glass tube, or simply a perfume container opened in one corner of the room (gaseous diffusion) Diffusion and osmosis animation and text: http://www.bbc.co.uk/scotlan d/revision/biology/investigatin g_cells/cells_and_diffusion_r ev.shtml#diffusion Emphasise the random motion of particles. Consider the relevance of thjs to living organisms – for example, the diffusion of oxygen and carbon dioxide into and out of a plant leaf or across the surface of the alveoli in the human lungs. Diffusion and osmosis interactive animations: http://physioweb.med.uvm.ed u/bodyfluids/osmosis.htm Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 4.3 Learning Outcomes Define osmosis as the passage of water molecules from a region of their higher concentration to a region of their lower concentration, through a partially permeable membrane. Describe the importance of osmosis in the uptake of water by plants and its effects on plant and animal tissues. Suggested Teaching Activities Osmosis should be treated as a special case of diffusion, in which only water molecules are able to move from one side of a partially permeable membrane to another. Ensure that students understand what a solution is in terms of particles, so that they are able to imagine the water molecules and solute particles behaving independently of each other. Use visking tubing to demonstrate osmosis. Investigation of changes in mass or length of potato chips placed in a range of different sugar solutions provides good opportunity for quantitative treatment of results, as well as enhancing understanding of osmosis. Discuss differences in the effects of water uptake and loss on animal cells and plant cells in terms of the absence and presence of the plant cell wall. Turgor as an important mechanism of support in plants could be discussed. Relate water uptake by osmosis back to the structure of root hair cells covered earlier in this Unit. II 4.3 Understand the concept of a water potential gradient. Explain water potential as the tendency for water to leave a solution. The more water (that is them more dilute the solution) the higher the water potential. Water moves from a high water potential to a low water potential – that is, down a water potential gradient. Do not introduce the idea of negative water potentials at this level. Online Resources Visking tubing expt – interactive http://www.mhhe.com/biosci/ esp/2001_gbio/folder_structu re/ce/m3/s3/cem3s3_3.htm Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 4.2 II 5 Learning Outcomes Define active transport and discuss its importance as an energy-consuming process by which substances are transported against a concentration gradient, e.g. ion uptake by root hairs and uptake of glucose by epithelial cells of villi. Define enzymes as proteins which function as biological catalysts. Suggested Teaching Activities No detail of the molecular mechanism of active transport needs to be considered. Students should understand that energy for this process is provided by respiration. Describe the effect of changes in temperature and pH on enzyme activity. Revise the meaning of the term ‘catalyst’. Ensure that students understand that enzymes are simple molecules, not living organisms. They cannot, therefore, be ‘killed’. Simple experiments with catalase are an excellent introduction to enzymes. Investigate the effect of temperature on the effect of enzyme activity, for example using starch and amylase, or pepsin and milk powder. Explain the rise in activity with temperature in terms of kinetic theory, and the fall as temperature rises in terms of denaturation of the enzyme molecules. Consider the different optimum temperatures of different enzymes, not only those in humans. Online Resources Simple account of how enzymes work: http://www.activesciencegsk.com/miniweb/content/en zymes/how_do.htm Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 5 Learning Outcomes Describe the role of enzymes in the germination of seeds and their uses in biological washing products and in the food industry. Outline the use of microorganisms and fermenters to manufacture enzymes for use in biological washing powders. Suggested Teaching Activities The role of amylase in the breakdown of starch to maltose in seeds provides an example of enzymes in plants. Germinating barley seeds, dipped into a sterilising solution to destroy any micro-organisms on their surfaces, can be placed on sterile starch agar in a petri dish, which can later be tested for starch with iodine solution. Proteases, lipases and amylases, often with high optimum temperatures, are all used in biological washing powders. Investigations can be carried out into the effectiveness of these in removing different types of stains. Simple experiments on the effect of pectinase on the yield of juice from crushed apples can be carried out. Online Resources Downloadable booklet 'Practical Biotechnology', with practical investigations using a variety of enzymes http://www.ncbe.reading.ac.u k/NCBE/PROTOCOLS/pracb iotech.html Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 2: Animal Nutrition Recommended Prior Knowledge Students can come into this Unit with very little biological knowledge. However, they do need to understand the concepts of elements and compounds, and of atoms, molecules and ions, and should be familiar with simple chemical reactions. Context The molecules that make up the bodies of living things are introduced here, and will be referred to in all of the subsequent Units. Outline This Unit considers the molecules from which living organisms are made, and then looks in detail at how animals acquire the materials that they need to form the structure of their bodies, and also to supply energy. The way in which small molecules can be used to make larger ones is briefly considered, before thinking about how such large molecules need to be broken down again before they can be absorbed through the wall of the alimentary canal. The functions of the main digestive enzymes are considered, linking back to the work on enzymes in Unit 1. The use of food to supply energy will be covered in more detail in Unit 4, and the functions of the liver in glucose and amino acid metabolism, touched on very briefly here, will be treated in more depth in Units 5 and 6. II 6 II 6.1 Learning Outcomes Define nutrition as the obtaining of organic substances and mineral ions from which organisms obtain their energy and their raw materials for growth and tissue repair. Suggested Teaching Activities Discuss the need for materials to build bodies, and for energy to maintain their activities. A simple definition of an organic substance is one whose molecules contain carbon and hydrogen. List the chemical elements which make up: carbohydrates fats proteins Describe the synthesis of large molecules from smaller basic units, i.e. simple sugars to starch and glycogen amino acids to proteins fatty acids and glycerol to fats and oils. Ensure that students have some understanding of the terms element, atom and molecule. Beads that string together, or simple chemical modelling kits, can be used to illustrate the idea of small molecules joining together to make larger ones. They should understand that starch is found only in plants, never in animals. Online Resources Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK Learning Outcomes Describe tests for starch (iodine solution), reducing sugars (Benedict's solution), protein (biuret test) and fats (ethanol) Suggested Teaching Activities Students should have the opportunity to carry out each of these tests on a range of foods. This can also give useful practice in recording results and conclusions in a clearly presented results chart. Online Resources II 6.1 List the principal sources of, and describe the importance of: carbohydrates, fats, proteins, vitamins (C and D only), mineral salts (calcium and iron only), fibre (roughage) and water - Describe the deficiency symptoms for vitamins (C and D only) and mineral salts (calcium and iron only). Diets in most countries depend on a staple food such as bread or rice, which is usually the main source of carbohydrate. Students should be aware of the main sources of each type of nutrient in their own country, but also be prepared to consider how diets differ in other parts of the world. The Association for Science Education. College Lane, Hatfield, Herts, AL10 9AA, England, has a project called Science Across Europe, which includes a unit on diet, and which encourages schools in different parts of the world to share information. US Agency for International Development’s information on the nutritional contents of a wide variety of foods: http://www.usaid.gov/hum_re sponse/crg/fssfcor nmeal.htm II 6.3.1 Understand the concept of a balanced diet describe: a balanced diet related to age, sex and activity of an individual the effects of malnutrition in relation to starvation, coronary heart disease, constipation and obesity Students can keep a record of the food that they eat during one day, and then consider whether they are obtaining the nutrients that they need. The booklet 'Food Tables', Bender and Bender, published by Oxford University Press, is a good source of information about energy and nutrient contents of a very wide range of foods. Balanced diet http://www.sambal.co.uk/diet. html II 6.1 Malnutrition should be considered as the result of eating an unbalanced diet, not just the lack of a particular type of nutrient. Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK Learning Outcomes Discuss: the problems of world food supplies the problems which contribute to famine (unequal distribution of food, drought and flooding, increasing population) Suggested Teaching Activities Material to illustrate this topic, and to form the basis of discussion, can be collected from newspaper and television reports. Students may like to consider whether new technologies, such as the development of genetically modified varieties of crops, are likely to improve the situation or exacerbate it. Online Resources Technology to Feed the World http://www.nationalacademie s.org/webextra/crops/ A discussion of the problems of feeding the world's growing population, with excellent links to many other site II 6.1 Describe the use of micro-organisms in the food industry, with reference to yoghurt, bread and single cell protein. There is plenty of opportunity for practical work involving yoghurt production, and the use of yeast for bread-making. A good source of ideas for this is the booklet 'Practical Biotechnology'. downloadable booklet 'Practical Biotechnology', with practical investigations into yoghurt production and bread-making http://www.ncbe.reading.ac.u k/NCBE/PROTOC OLS/ II 6.1 Describe the uses, benefits and health hazards associated with food additives including colourings. The health benefits of preservatives, in terms of greatly reduced risk of food poisoning, should be emphasised. Antioxidants also increase storage times for many foods. Flavourings and flavour enhancers increase palatability. A few artificial colourings, such as tartrazine, have been associated with problems such as hyperactivity. II 6.3.1 Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 6.3.2 II 6.3.3 Learning Outcomes Identify the gross structure of the alimentary canal and associated organs (mouth, oesophagus, stomach, small intestine: duodenum and ileum, large intestine: colon and rectum, anus, pancreas, liver) Define ingestion, digestion, absorption, assimilation and egestion Describe the functions of the alimentary canal's various parts in relation to ingestion, digestion, absorption, assimilation and egestion of food Suggested Teaching Activities Students often do not understand that the alimentary canal is a long tube - albeit a coiled one - through which food passes. They also need to understand that food cannot be considered to have entered the body until it crosses the wall of the canal. Identify the types of human teeth and describe their functions. State the causes of dental decay and describe the proper care of teeth describe the processes of chewing and peristalsis. Students can think about the functions of the different types of teeth as they eat. Chewing increases the surface area of food, making it easier for enzymes to act on it during the later stages of digestion. Dental decay should be thought of as the result of bacteria producing acids, which damages enamel. It should be made clear that peristalsis happens all through the alimentary canal, not just in the oesophagus. The need for digestion before absorption can take place can be investigated using Visking tubing (to represent the alimentary canal) containing a mixture of glucose, starch and water. This is placed in a beaker of water (to represent the blood), and left for long enough for the glucose to diffuse across the tubing. The contents of the tubing and of the beaker can be tested for starch and for glucose Online Resources http://borg.com/~lubehawk/h digsys.htm Includes a quiz on the parts of the alimentary canal Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 6.3.3 II 6.3.4 II 6.3.5 II 6.3.5 II 6.3.6 Learning Outcomes Explain the probable action of fluoride in reducing tooth decay and present arguments for and against its addition to public water supplies. Suggested Teaching Activities Although most health professionals strongly support the addition of fluoride to water supplies, there are also some arguments against this. Describe: Digestion in the alimentary canal, the functions of a typical amylase, protease and lipase, listing the substrate and end-products. Identify the small intestine as the region for absorption of digested food. Describe the significance of villi in increasing the internal surface area. Describe the structure of a villus including the role of capillaries and lacteals. Indicate the role of the hepatic portal vein in the transport of absorbed food to the liver. Describe: the role of the liver in the metabolism of glucose and in the destruction of excess amino acids, the role of fat as a storage substance. This topic should be linked with earlier work on enzymes, in Unit 1 (section II.5). Students should also know in which parts of the alimentary canal these enzymes are found. Core students do not need any detail of the villus structure. The absorption of glucose should be linked with earlier work on active transport, in Unit 1 (section II.3). For Core students, no detail of the hormonal control of glucose levels is required. They should, however, know that the liver stores excess glucose as glycogen (link back to section II 6.1) and converts this back to glucose again if blood glucose levels fall. The conversion of excess amino acids to urea should be dealt with very simply; this will be covered again in Unit 5. Online Resources Fluorides and fluoridation http://www.ada.org The American Dental Association's site dealing with the fluoride issue. The Story of Fluoridation http://www.nidcr.nih.gov/Healthinforma tion/OralHealthInformationIndex/Fluori de/StoryFluoride.htm A history of the introduction of fluoride into water supplies in the USA, from the National Institute of Dental and Craniofacial Research. Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 3: Plant Nutrition and Transport Recommended Prior Knowledge Students should know something of carbohydrates and proteins, the structure of a plant cell, and osmosis, all of which were dealt with in Units 1 and 2. They should have an understanding of energy transfers from one form to another. Context This Unit builds on ideas from Units 1 and 2. Concepts from this Unit will be revisited in Units 9 and 10. Outline This Unit covers most of the plant physiology topics. There is a considerable range of practical work that can be carried out, much of which can be used to develop or to assess practical skills. Teachers working in countries where there are marked seasons will need to take this into consideration when planning the timing of this Unit. The Unit begins by looking at the way in which plants manufacture organic substances using sunlight and inorganic molecules as their raw materials. Extension candidates look a little more deeply into the way in which environmental factors affect the rate of photosynthesis, and how these factors can be controlled in glasshouse cultivation. Knowledge of cell structure, covered earlier in Unit 1, is extended to look more fully at the structure and function of cells and tissues in a leaf, and the idea of adaptation of structure to function is re-emphasised. The movement of water from soil to air in xylem, and of organic products of photosynthesis in phloem, is considered. Extension candidates should think about a range of examples of adaptations of plants to living in extreme conditions. Some wider issues relating to this Unit, such as the position of plants as producers in an ecosystem, and problems associated with the use of fertilisers and pesticides, will be considered in Unit 10. II 6.2.1 Learning Outcomes Define photosynthesis and state the equation for the production of simple sugars and oxygen in either words or symbols describe the intake of the raw materials, the trapping and storing of energy (conversion of light energy into chemical energy) and the formation of food substances and their subsequent storage. Suggested Teaching Activities Plants can be considered as 'food factories', in which all the food in the world is initially made. Students should compare the needs of animals for organic nutrients (covered in Unit 2) with those of plants, which only require inorganic ones such as carbon dioxide and water. Online Resources Photosynthesis http://eduref.org/cgibin/printlessons.cgi/Virtual/Less ons/Science/Botany/BOT0046.h tml Simple photosynthesis experiments The initial products of photosynthesis are sugars (such as glucose) which can then be converted to large, insoluble molecules such as starch for storage. Investigating the behaviour of leaf discs http://wwwsaps.plantsci.cam.ac.uk/worksh eets/activ/prac5.htm Instructions for a slightly different way of investigating the production of starch during photosynthesis, using leaf discs. The process of photosynthesis should be considered at a fairly basic level; there is no need to introduce the ideas of lightdependent and light-independent stages. The important point to get across is the Other Resources IGCSE BIOLOGY 0610 SCHEME OF WORK conversion of light energy to chemical energy. Chlorophyll absorbs light energy and enables it to be used to drive the reactions. (Ensure that students do not think that chlorophyll attracts light!) II 6.2.1 Define the term limiting factor, interpret (as limiting factors which affect photosynthesis) the effects of light intensity and carbon dioxide concentration explain the use of carbon dioxide enrichment, optimum light and optimum temperatures in greenhouse systems. There is a wide variety of practical work that can be carried out. Students should know how to test a leaf for starch, and carry out simple experiments into the need for light and chlorophyll for photosynthesis. Limiting factors should be dealt with relatively simply, as anything which limits the rate of photosynthesis if it is in short supply. Simple graphs can be sketched showing the effect of increasing light intensity or carbon dioxide concentration on the rate of photosynthesis, and students should be able to explain why such a graph initially rises and then flattens out. They can use Elodea or other water plants to investigate the effects of light intensity on the rate of oxygen production. Greenhouse systems are most widely used in temperate countries, and students living in countries where their use is not widespread should be prepared to consider the need for them in relatively cool climates. Various teacher and student resources on photosynthesis (register to use site) http://www.riverdeep.net (/science/biology_explorer/be_a ctivity_pages/catn.activityi_393.j html;$sessionid$1RXTXLJNJV MGACQFAGMCIIQKAUA ZOI5G) IGCSE BIOLOGY 0610 SCHEME OF WORK II 6.2.2 Learning Outcomes Identify the cellular and tissue structure of a dicotyledonous leaf, as seen in cross section, and demonstrate the significance of these features in terms of functions, i.e. distribution of chloroplasts – photosynthesis stomata and mesophyll cells – gaseous exchange vascular bundles (xylem and phloem) - transport Suggested Teaching Activities Before considering the appearance of a section through a leaf, students should look at entire leaves and consider how they are adapted for photosynthesis. A transparency of a section through a leaf can be projected and discussed, before a simplified diagram is made of a leaf section. Students should already be familiar with the structure of a palisade cell, and can now consider it as part of tissue that is specialised for photosynthesis. It can be helpful to think of a leaf as a food factory, and then to consider how the raw materials are brought to it, and how the products are removed for distribution. Drawings of leaves, and comparisons between two or more different kinds of leaves, make good practice or assessment material for the practical skills of observation and recording, and also for magnification calculations. It is probably best not to go into any detail at this point about xylem and phloem function; they will be dealt with a little later. II 6.2.3 Describe: the importance of nitrate ions for protein synthesis and magnesium ions for chlorophyll synthesis. Students should be reminded that carbohydrates contain carbon, hydrogen and oxygen only; plants can therefore make these from carbon dioxide and water. However, proteins also contain nitrogen, so a nitrogen source is necessary before some of the carbohydrate can be converted to protein. Nitrate ions from the soil are the main source of nitrogen for plants. For Online Resources Photomicrograph of Eleagnus leaf TS with vascular bundle http://images.botany.org/set13/13-063v.jpg Other Resources IGCSE BIOLOGY 0610 SCHEME OF WORK extension candidates, a link can be made back to the uptake of ions by root hairs (II.3). It may be best not to deal with the use of nitrogen fertilisers here, but rather to cover this fully in Unit 10 (IV.5.1). II 6.2.3 II 7.1.1 Explain the effects of nitrate ion and magnesium ion deficiency on plant growth. Identify root hair cells as seen under the light microscope and describe their functions describe the passage of water through root, stem and leaf. This should be dealt with simply, considering the effects on a growing plant of a shortage of proteins or chlorophyll. Root hair cells may already have been covered in Unit 1 (section II.2) as an example of a specialised cell, but here they are dealt with in the context of the whole plant. Osmosis should be revised, before discussing the uptake of water through the soil, across the root, and up through xylem. Xylem, also, may have already been discussed in Unit 1 (section II.2) and Unit 2 (II.6.2.2). Here it is considered in the context of water transport from root to leaves. If the structure of xylem vessels has not already been dealt with, then it should be simply covered here. No detail is required other than the idea that a xylem vessel is made of a long column of dead, empty cells with lignified walls, stacked end to end. Students will find the path taken by the water easier to understand if they have a simple knowledge of the position of the vascular bundles in the plant. Simple diagrams can be made of a TS of a root and of a stem, showing the xylem and phloem. Roots http://www.ffp.csiro.au/research/ mycorrhiza/root.html Diagrams & descriptions of root structures IGCSE BIOLOGY 0610 SCHEME OF WORK Large and semi-transparent stems, such as the leaf petioles of celery, can be placed with their bases in a solution of a watersoluble dye. After some time, the dye can be seen in the xylem vessels, spreading out into the veins in the leaves. If thin sections are cut, the positions of the xylem vessels show up clearly. II 7.1.2 Define transpiration Describe: How water vapour loss is related to cell surfaces, air spaces and stomata. The effects of variation of temperature, humidity and light intensity on transpiration rate. How wilting occurs. It is important to understand that transpiration involves the loss of water vapour from the leaf, mostly through open stomata. Water in the cell walls of mesophyll cells evaporates, and diffuses through the air spaces and out of the leaf. Experiments using potometers not only help students to understand the effects of environmental factors on the rate of transpiration, but also provide good opportunities to improve, or to be assessed on, all four experimental skills. It is important, however, that it is understood that a photometer measures water uptake, which is not absolutely the same as water loss. There is no need for elaborate potometers; all that is needed is a long piece of capillary tubing with a length of rubber tubing at one end into which the cut end of a shoot is pushed. Keep everything under water while assembling the apparatus, to avoid air locks. If students are shown a wilting plant, they can think about why it is only the leaves that wilt. This can introduce the idea of xylem vessels, present in vascular bundles Transpiration described & experiment to carry out http://www.mcgrawhill.ca/school /booksites/sciencefocus+8/stud ent+resources/by+resource+typ e/cool+stuff+to+see+and+do/uni t+2+topic+5+hands+on+activitie s.php IGCSE BIOLOGY 0610 SCHEME OF WORK II 7.1.2 Describe the mechanism of water uptake and movement in terms of 'pull' from above, creating a water potential gradient through the plant. II 7.1.2 Describe the adaptations of the leaf, stem and root to different environments, with emphasis on local examples. in leaves and stem, helping with support. Wilting is a good way for a plant to avoid further water loss, by reducing the leaf area from which evaporation can occur. Extension candidates will probably already have met the term 'water potential', in Unit 1 (section II.4). In normal conditions, the water potential in the air is lower than that in the soil solution. Thus water moves down a water potential gradient as it moves from soil to air, through the plant. The effect of transpiration in pulling water up xylem vessels can be compared to the effect of sucking a liquid up a straw. Although students should look at examples of plant adaptations using plants that grow locally, it is also very useful to think about plants that grow in especially wet or dry environments, such as rain forest or desert. Desert plant survival http://www.desertusa.com/du_pl antsurv.html Good descriptions of plant adaptations for survival in hot, dry regions. Plant adaptations http://www.microscopyuk.org.uk /mag/articles/anne1.html Microscope images of xerophytes and hydrophytes (plants that live in water), emphasising their adaptations. TS Marram grass photomicrograph http://www.microscopyuk.org.uk /schools/mainscol.html#plant II 7.1.3 Define translocation in terms of the movement of sucrose and amino acids from regions of production or of storage to regions of utilisation in respiration or This idea will probably already have been met earlier in this Unit, when discussing the functions of leaves. Here it should be reemphasised that carbohydrates are IGCSE BIOLOGY 0610 SCHEME OF WORK growth. II 7.1.3 Describe translocation, throughout the plant, of applied chemicals including systemic pesticides. transported through a plant in the form of sucrose, through phloem. No detail of phloem structure or function is required. It should be made clear that substances can be transported in any direction in phloem, for example from photosynthesising leaves down to roots, or from storage organs such as root tubers upwards to leaves and flowers. Consideration of the effects of 'ringing' a tree can help students to bring together their knowledge of stem structure and function. Ringing removes the phloem, which is near to the surface of a stem. If the ring is cut below the leaves, then all the cells beneath the ring are deprived of products of photosynthesis from the leaves, and eventually die. Students should understand that systemic pesticides are sprayed onto the plant, and then absorbed by it. They move through the plant in the phloem, and are taken in by any insect eating the plant or sucking up phloem sap. IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 4: Respiration and the human transport system Recommended Prior Knowledge: Students need to have some knowledge of energy transfer, and be able understand simple chemical equations. Context: Respiration is a fundamental process that will be referred to in most of the subsequent units. Outline: This Unit covers the important topic of respiration, which will be met again when the carbon cycle is dealt with in Unit 9. Gas exchange in humans, and the effects of cigarette smoke lead on from this. In animals, unlike plants, the transport system is involved in the carriage of gases between the gaseous exchange surface and the body tissues, and so coverage of this leads on naturally from a consideration of gas exchange. Some teachers, however, may prefer to deal with transport first, and then respiration; there are sound arguments for either sequence. There is considerable opportunity for practical work in the respiration topics, but it is much less easy to carry out much practical work in the transport sections. II 8 II 8.1 Learning Outcomes Define respiration as the release of energy from food substances in all living cells. Define aerobic respiration state the equation for aerobic respiration, using either words or symbols name and describe the uses of energy in the body of humans. Suggested Teaching Activities Ensure that, right from the start, students understand that respiration is a reaction (or series of reactions) that takes place inside living cells. A very common error is to confuse it with 'breathing', and to think that it takes place only in the lungs. They should also realise that every cell respires, even plant cells. Emphasise that the function of respiration is to release energy from food (usually glucose) in a form that the organism can use. Students should not state that respiration 'produces' energy! A class discussion will probably pick out a good range of uses of energy in the human body, such as muscle contraction, nerve impulses and keeping warm. It can be helpful to compare respiration with combustion - the overall equation is the same, but respiration occurs in a series of small reactions that do not suddenly release large amounts of heat energy. The energy content of a food, such as a nut, can be estimated by allowing it to heat a Online Resources Introduction to respiration http://wow.nrri.umn.edu/wow/ student/photo/cellintro.html Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK II 8.2 Define anaerobic respiration state the equation for anaerobic respiration in muscles and yeast using either words or symbols describe: its role in brewing and breadmaking the production of lactic acid in muscles during exercise compare aerobic respiration and anaerobic respiration in terms of relative amounts of energy released. II 8.3 List the features of gaseous exchange surfaces in animals. known volume of water as it burns in air. (This investigation is often done using peanuts, but teachers should be very aware that an increasing number of children are allergic to peanuts. A cube of bread makes a safer alternative food to be burnt.) Anaerobic respiration can be investigated using a suspension of yeast in boiled, cooled water. Boiling drives off all dissolved oxygen. The carbon dioxide released can be detected by passing it through lime water or hydrogencarbonate indicator solution. Extension students may already have investigated the use of yeast in breadmaking, in Unit 2 (section II 6.1). If not, this is a good opportunity for all students to investigate, for example, whether adding amylase or ascorbic acid, affects the rate at which dough rises. Anaerobic respiration in muscles will be revisited later in this Unit, when oxygen debt is considered. The idea of gaseous exchange may already have been thought about in Unit 3, in the context of the intake and loss of gases from leaves. A gaseous exchange surface can be defined as a surface across which gases pass as they enter or leave the body. For animals, oxygen enters as carbon dioxide leaves. Students should be reminded of what they know about diffusion, and then suggest features of a surface that would enable diffusion to take place as quickly as possible. IGCSE BIOLOGY 0610 SCHEME OF WORK II 8.3 State the differences in composition between inspired and expired air. Describe a test for carbon dioxide. II 8.3 Describe the effects of physical activity on rate and depth of breathing. II 8.3 Describe the effects of tobacco smoke and its major toxic components on the respiratory system. The differences between expired and inspired air, in terms of carbon dioxide content and water vapour content, should be investigated experimentally. Lime water or hydrogencarbonate indicator may be used to test for carbon dioxide. Students should be able to use their knowledge of gas exchange and respiration to explain these differences. This should be investigated experimentally. A simple, repeatable form of exercise, such as step-ups, is the most useful for generating quantitative results. Students should use their knowledge of aerobic and anaerobic respiration to explain why breathing rate does not drop immediately to normal when exercise stops. Students will need some basic knowledge of the structure of the breathing system trachea, bronchus, bronchioles and alveoli, and of ciliated and goblet cells, before thinking about how these structures are affected by tobacco smoke. They should understand that cilia become less active, and goblet cells more active, when exposed to cigarette smoke, so that mucus collects in the lungs. Bacteria are likely to breed in it, leading to bronchitis and other infections. Alveoli lose their elasticity, and coughing may damage their walls, leading to emphysema. Cancer can be triggered by exposure to many of the chemicals in tar. The lungs - an overview of how they work http://www.lungnet.org.au/fra me_learnhealth.htm Emphysema http://www.lungusa.org/site/a pps/s/content.asp?c=dvLUK9 O0E&B=34706&ct=67284 IGCSE BIOLOGY 0610 SCHEME OF WORK II 8.3 Describe the role of ribs, internal and external intercostals muscles and diaphragm in ventilation of the lungs. II 7.2.1 Describe: The gross structure and function of the heart. The double circulatory system The effect of exercise on heart beat II 7.2.1 List the likely causes of hear attack (diet, smoking, stress), and preventative measures. II 7.2.2 Describe the structure and functions of arteries, veins and capillaries. Explain how structure & function are related in arteries, veins and capillaries. Students often find this topic difficult, and it is a good idea to use a model of some kind to illustrate how increasing the volume of the thorax leads to a reduction in pressure. The 'balloons in a bell jar' model shows this effectively. Diagrams of the heart, showing both external and internal structure, need to be known. Ensure that students realise that both sides of the heart beat together. The direction of blood flow through the heart, the separation of oxygenated and deoxygenated blood, and the functions of the valves should be understood. It is recommended that the idea of a double circulatory system, in which blood passes twice through the heart during one complete circuit of the body, is covered here, as this helps to make sense of the structure and function of the heart. The effect of exercise on heart beat relates closely to the effects of physical activity on rate and depth of breathing, dealt with earlier in this Unit. Students may already have some ideas about factors that increase the likelihood of suffering from heart disease, and class discussion will probably bring out most of the major influences. A person's genes are also thought to play a major role in this. Transparencies or microscope slides of sections through an artery and a vein can be used to help students to understand the differences between them. They should be able to explain the differences in terms of the high, pulsing blood pressure in arteries, and the much lower pressure and smoother flow in veins. Emphasise that arteries do not pump blood. Structure of your heart http://www.wehealnewyork.or g/services/cardiology/structur e.html Animation of heart beat http://web.ukonline.co.uk/we bwise/spinneret/circuln/anca d.htm IGCSE BIOLOGY 0610 SCHEME OF WORK II 7.2.3 Identify blood cells as seen under a light microscope, describe: the components of blood the functions of blood, including clotting (no details of clotting required) the transfer of materials between capillaries and tissue fluid Again, students should see transparencies or microscope slides of stained blood samples, and be able to distinguish red cells, white cells and platelets. They should understand that red cells transport oxygen and also carbon dioxide, and know that they contain haemoglobin. Links can be made back to Unit 2, and the need for iron in the diet. This is a good place to discuss the adaptations of red blood cells to their functions, if this has not already been covered in Unit 1. White cells, on the other hand, protect the body from invading pathogens. No detail of this is required by Core students. Clotting should be mentioned, as a mechanism to prevent loss of blood and entry of pathogens, but Core students need no detail at all of how it takes place, other than that platelets are involved. II 7.2.3 Describe the process of clotting (fibrinogen to fibrin only). II 7.2.3 Describe the immune system in terms of antibody production, tissue rejection and phagocytosis. Tissue fluid can be thought of simply as plasma that has leaked out of capillaries. Diffusion can be revised, and students should be able to use their knowledge of respiration to suggest substances that move from blood to tissues and vice versa. Extension students need to understand that fibrinogen is a soluble protein, which is converted to the insoluble fibrin when a blood vessel is damaged. Calcium is required for this, so links can be made back to Unit 2. A relatively simple approach to this complex topic is required. Some white blood cells are phagocytes, and the process of phagocytosis should be understood. Lymphocytes, however, IGCSE BIOLOGY 0610 SCHEME OF WORK II 7.2.3 Describe the function of the lymphatic system in circulation of body fluids and the production of lymphocytes. secrete antibodies (which are proteins) in response to contact with their particular antigen, which may be an invading pathogen or a foreign tissue that has been transplanted. Students may be interested to learn how immunity to a disease can be conferred by vaccination. This topic also links with kidney transplants, covered in Unit 5. This is another potentially difficult topic, which should be dealt with simply. Tissue fluid (dealt with earlier in this Unit) drains into lymph vessels, which carry it slowly back to the main circulatory system through vessels with valves. It is worth pointing out that lacteals, dealt with in Unit 2, are part of the lymphatic system. IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 5: Coordination, Response and Homeostasis Recommended Prior Knowledge: Knowledge of cell structure, osmosis, respiration and enzyme activity will help students to understand why homeostasis is important in mammals. It will also be helpful if they have some understanding of the behaviour of light, lenses, and how to draw simple ray diagrams before beginning work on the human eye. Extension candidates need a simple knowledge of the immune response in order to discuss the difficulties associated with kidney transplants. Context: This Unit provides numerous opportunities to revisit ideas and facts covered in earlier Units. Outline: The theme running throughout this unit is communication within the body, both through chemicals and the nervous system. Both plants and animals are dealt with, and students encouraged to see how similar are the mechanisms by which they achieve responses to stimuli. Once the basic function of the nervous system has been covered, the effects on it of drugs such as alcohol and heroin are considered. Homeostasis is illustrated for all candidates by temperature regulation in humans, while extension candidates take these ideas further, looking at the control of blood glucose concentration and taking an overview of how negative feedback is involved in control mechanisms. A simple treatment of excretion in humans completes the Unit. II 10.1 Learning Outcomes Define hormone. Describe the chemical control of metabolic activity by adrenaline. II 10.1 Discuss the use of hormones in food production. Suggested Teaching Activities Adrenaline makes a good introduction to the idea of hormones, as everyone is aware of its effects. Discussion will bring out most of these, and students should be able to suggest how they help to prepare the body for 'fight or flight'. A hormone can be defined as a chemical that is secreted from ductless (endocrine) glands, and that is transported in the blood system all around the body, where it has an effect on its target organs. This is also a suitable point at which to discuss the general need for communication systems in the body, and the ideas of receptors and effectors. The use of BST in milk and meat production can be discussed. Online Resources Bovine Somatotropin http://project.bio.iastate.edu/course s/Gen308SS99/BIOTECH_INFO/n cr488.html A balanced description of the use and effects of BST Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK Posilac - an introduction http://www.monsantodairy.com/abo ut/index.html A view from the firm that makes and sells BST II 10.2 Define geotropism and phototropism. II 10.2 Describe geotropism and phototropism in terms of auxins regulating differential growth describe the chemical control of plant growth by auxins and the effects of synthetic plant hormones used as weedkillers. II 10.2 Describe simple behaviour in terms of the taxic responses of invertebrates. Having dealt with the idea of how animals may respond to stimuli (with respect to adrenaline), students can now think about how plants do this. Geotropism and phototropism should be investigated with simple experiments. It should be made clear that these are growth responses, in which the direction of growth is related to the direction of the stimulus. Once again, as in animals, receptors and effectors can be identified. There is still some controversy over just how geotropism and phototropism are regulated. A relatively simple possible mechanism, involving unequal distribution of auxin, should be considered. If it is possible to obtain IAA, then simple investigations can be carried out into its effects. Students should also consider the similarities and differences between animal hormones such as adrenaline, and plant hormones such as auxins. It is quite a jump from thinking about plant hormones to looking at simple behavioural responses in animals, but again the common factors of receptors and effectors, stimulus and response, can be Investigating plant growth regulators http://wwwsaps.plantsci.cam.ac.uk/worksheet s/activ/prac4.htm An experiment involving the use of IAA on mustard seedlings. IGCSE BIOLOGY 0610 SCHEME OF WORK II 10.3 Describe the human nervous system in terms of the central nervous system (brain and spinal cord as areas of coordination) and the peripheral nervous system. II 10.3 Define sense organs as groups of receptor cells responding to specific stimuli: light, sound, touch, temperature and chemicals. emphasised. A taxic response in an animal is in many ways like a tropic response in plants, in that the direction of the response is related to the direction of the stimulus. The main difference is that in plants the response is growth, while in animals it is movement. Maggots (fly larvae) can be used for simple experiments investigating their directional response to light. (Note that the responses by woodlice, for example in choice chambers, do not illustrate taxis but kinesis; the response is the rate of movement or rate of turning, not a directional response.) Students need to be encouraged to think about these responses as automatic ones, that do not involve any 'thinking' by the animals. Diagrams or models can be used to illustrate the positions of brain, spinal cord and peripheral nerves in the human body. Ensure that there is no confusion between spinal cord and vertebral column. Lamb chops often have a small piece of spinal cord on them, lying in the groove of a vertebra, and this can be used to show students what the cord looks like, and also how it is protected by the surrounding vertebrae. The idea of receptor and effector is returned to now, with a detailed look at what receptors do, and one example of a receptor in humans. Models of the eye are helpful in aiding understanding of its Neuroscience for kids http://faculty.washington.edu/chudl er/neurok.html Despite the title, some of the material at this site is a little advanced for IGCSE students. IGCSE BIOLOGY 0610 SCHEME OF WORK Describe the structure and function of the eye including accommodation. II 10.3 II 10.3 Distinguish between rods and cones in terms of function and distribution. Describe effectors in terms of muscles and glands describe the action of antagonistic muscles in terms of biceps and triceps and associated bones. II 10.3 Identify motor and sensory neurones from diagrams. Describe a simple reflex arc in terms of sensory, relay and motor neurones and a reflex action as a means of integrating and coordinating stimuli with responses. Describe the pupil reflex. II 10.3 Distinguish between voluntary and involuntary actions. structure and function. A round flask of fluorescein with a convex lens at the front can be used to show how light is focussed on to the retina (the back of the flask). It may be possible to dissect an eye, for example from a sheep. Students can also draw and interpret views of their own eyes, using a mirror. Rods and cones should be considered as examples of receptor cells. As for receptors, one example of effectors is considered in detail. They can feel the biceps and triceps muscles in their own arm, and think about what each of them is doing as the arm is bent and straightened. It is important to understand that muscles can contract and relax, but cannot make themselves shorter - hence the need for two antagonistic muscles to work together. Having looked at receptors and effectors, the way in which communication is achieved between them through the nervous system is now considered. Students can think about examples of reflex actions, in each case identifying the stimulus and response, and the receptor and effector that are involved. The pupil reflex is a good example of a reflex action, and students can see this in their own eyes, by covering one or both eyes with something dark and then allowing light to fall on them. By now, a number of simple responses have been covered, and extension candidates should begin to realise that many of these are involuntary. They should be able to suggest a number of voluntary IGCSE BIOLOGY 0610 SCHEME OF WORK II 10.3 Compare nervous and hormonal control systems. II 10.5 Describe the effects of alcohol and heroin and the dangers of their misuse. and involuntary actions, listing stimulus and response in each case. Students can now be asked to think back over the work covered so far in this Unit, and to identify similarities and differences between the examples they have dealt with involving communication by hormones, and by them nervous system. A table summarising these can be built up. Most of the effects of alcohol and heroin involve the nervous system, although they do both affect other body organs. Describe the personal and social problems arising from drug abuse, by reference to alcohol and heroin. Alcohol http://www.health.org/features/kids area/funstuf/brain/default.aspx Despite the title, some of the material at this site is a little advanced for IGCSE students. FAQs on alcohol abuse http://www.niaaa.nih.gov/faq/faq.ht m II 10.4 Define homeostasis as the maintenance of a constant internal environment. II 10.4 Describe temperature regulation and explain the effects of sweating, vasodilation and vasoconstriction only. For most cells in the human body, their immediate environment is the tissue fluid that surrounds them. Students should think about why it is important to keep this environment relatively constant, and what features of it are controlled. Thinking back to earlier work on osmosis, enzyme activity and respiration will help with this. This can be introduced as an example of homeostasis, in which communication is achieved through the nervous system. A simple diagram of the skin can be drawn, showing the responses of sweat glands, arterioles and capillaries when the body temperature is too high and too low. Make sure that students do not think that the blood capillaries move up and down in the skin! Emphasise that the cooling effect of sweating is due to the evaporation of water. Homeostasis http://www.bbc.co.uk/schools/gcse bitesize/biology/humansasorganis ms/6homeostasisrev1.shtml IGCSE BIOLOGY 0610 SCHEME OF WORK II 10.4 Describe the control of the glucose content of the blood by the liver and by insulin and glucagon from the pancreas. II 10.4 Discuss the general role of negative feedback in homeostasis. II 9 Define excretion as the removal of toxic materials, the waste products of metabolism and substances in excess requirements from organisms. II 6.3.6 Define deamination as removal of the nitrogen containing part of amino acids as urea, followed by release of energy from the remainder of the amino acid Describe the formation of urea and the breakdown of alcohol, drugs and hormones in the liver. Describe the function of the kidney simply in terms of removal of urea and excess water and reabsorption of II 9 II 9 Extension candidates now look at another example of homeostasis, in this case with hormones achieving coordination between receptor and effector. They may also like to know something of diabetes, a relatively common disorder in many countries. They should consider why it is important to control blood glucose content, thinking back to what they know about osmosis and respiration. Correct spelling is essential to distinguish between glycogen and glucagon. Negative feedback will have featured in both temperature regulation and control of glucose content. Teachers could explain the role of negative feedback in one of these, drawing a flow diagram to show how it is achieved. Students can then draw a similar flow diagram to illustrate negative feedback in the second example. Excretion can be considered as another way in which the environment of cells is controlled, by removing waste products of metabolism. Ensure that they understand the difference between egestion (the removal of substances from the alimentary canal, that have never been part of the body at all) and excretion. Only a simple understanding of the formation of urea from excess amino acids is required. The role of the liver in breaking down alcohol and drugs may already have been touched on earlier in this Unit. This, too, should be dealt with very simply as even extension students will find details of nephron structure and function Understanding diabetes http://www.diabetes.org.uk/diabete s/index.html IGCSE BIOLOGY 0610 SCHEME OF WORK glucose and some salts (details of kidney structure and nephron not required) confusing. The relative positions of ureters, bladder and urethra in the body. II 9 II 9 Describe the function of the kidney as the filtration of water, glucose and salts out of the blood, followed by reabsorption of glucose, most of the water and some of the salts back in to the blood, leading to the concentration of urea in the urine, and loss of excess water. Explain dialysis and discuss its application in kidney machines. Discuss the advantages and disadvantages of kidney transplants, compared with dialysis. The importance of retaining glucose must be emphasised and it is excess water and salts which are excreted in urine. This will link back to section II 10.4 earlier in the unit which considers diabetes. Extension students will need to remember what they know about osmosis and diffusion in order to understand how dialysis works. They will also need to think back to their earlier work on the immune system and tissue rejection, when considering kidney transplants. About kidney disease and dialysis http://www.kdf.org.sg/health.htm The treatment of kidney failure http://www.kidneypatientguide.org. uk/site/dialysis.html IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 6: Reproduction in plants Recommended Prior Knowledge: A basic knowledge of cell structure will be helpful, but otherwise the Unit requires very little previous knowledge. Context: This Unit introduces the concept of reproduction that will be developed further in Unit 7. Outline: In this Unit, general features of both asexual and sexual reproduction are considered, before looking in detail at sexual reproduction in plants. The Unit should therefore be covered at a time of year when suitable flowers are likely to be available. It is suggested that mitosis and meiosis are briefly dealt with here, as they help with the interpretation of the distinction between asexual and sexual reproduction, although some teachers may prefer to leave this until genetics is covered. This Unit could be combined with Unit 7, Reproduction in humans. III 1.1 Learning Outcomes Define asexual reproduction Describe asexual reproduction in bacteria, spore production in fungi and tuber formation in potatoes. III 3.2 Describe mitosis simply, in terms of the exact duplication chromosomes resulting in identical daughter nuclei (details of stages are not required). Suggested Teaching Activities Ensure that students understand that 'asexual' means 'not sexual'. Asexual reproduction involves only one parent, which produces new organisms by mitosis. Fungal spores can be easily seen on bread moulds or mushroom gills, if these are allowed to develop well past the edible stage. Forethought is required to demonstrate asexual reproduction in potatoes, but apart from the time factor it is easy to demonstrate that planting one potato results in the production of many more. Although students have no knowledge of genetics yet, they will probably be aware that the nucleus of a cell contains chromosomes, and that these carry genes. Mitosis is a type of cell division that produces cells with identical chromosomes and genes to the parent cell. A simple series of diagrams showing how chromosomes behave during mitosis, with no names of stages, or details of spindles and so on, is all that is required. Online Resources Mitosis http://www.iacr.bbsrc.ac.uk/n otebook/courses/guide/mitosi s.htm Rather more detailed than is required at this level, but nevertheless students may enjoy visiting this site. Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK III 1.2 Define sexual reproduction. III 3.3 Describe the production of gametes by meiosis simply, in terms of halving of chromosome number leading to variation (details of stages not required). III 1.2.1 Describe the structure and functions of the flower of a named dicotyledonous plant. Define pollination and name the agents of pollination. Compare the different structural adaptations of insect-pollinated and wind-pollinated flowers. Sexual reproduction should be described as a process in which gametes fuse together in a process called fertilisation, producing a zygote. Make sure that students understand that this need not always involve two parents – selffertilisation, which is not uncommon in plants, is still sexual reproduction. Unlike asexual reproduction, sexual reproduction introduces genetic variation amongst the offspring. Students should think about how chromosome number can be kept constant during sexual reproduction, and discussion will probably bring out the idea that gametes must have only half the normal number of chromosomes if the zygote is to end up with the right number. The description of meiosis should be kept as simple as possible, concentrating on its results rather than any details of the process itself. It is probably best for extension candidates not to attempt to compare sexual and asexual reproduction until they know a little more about the latter process. Students should look closely at the structure of a simple, radically symmetrical insect-pollinated flower. They can dissect it to find all the different parts, and think about their functions. This is a good opportunity to develop or assess the practical skills of observation and recording. Samples of insect-pollinated and windpollinated flowers (grasses and cereals are What is a flower? Pollination http://www.thinkquest.org/libr ary/lib/site_sum_outside.html ?tname=3715&cid=2&url=37 15/flower.html%3ftqskip1=1& tqtime=0812 IGCSE BIOLOGY 0610 SCHEME OF WORK III 1.2.1 Describe the growth of the pollen tube and the process of fertilisation. Describe the formation of seed and fruit and the structure of a non-endospermic seed. good examples of the latter) can be studied and compared. Students could try growing pollen tubes. Fertilisation should be dealt with simply, There is no need for details of embyrosacs or all the different nuclei involved. However, do try to avoid the common misconception that the entire pollen grain moves down the style, or that the pollen is the male gamete. If possible, students should be able to watch a flowering plant through all the stages from flowering through to fruit and seed development. This helps them to understand how fruits and seeds develop after fertilisation. III 1.2.1 Define dispersal of seeds and fruits. Describe seed and fruit dispersal by wind and by animals. III 1.2.1 Discuss the advantages and disadvantages to the species of asexual reproduction. Discuss the advantages and disadvantages of sexual reproduction. The structure of seeds should be investigated practically. Soaked bean seeds are large and easy to see. A range of fruits should be looked at and the ways in which they are dispersed considered. A very common error is to confuse pollination with seed or fruit dispersal and care should be taken to avoid this. Now that they have looked at examples of both asexual and sexual reproduction, extension candidates should be able to consider the advantages and disadvantages of each process. Pollen tube growth http://wwwsaps.plantsci.cam.ac.uk/work sheets/ssheets/ssheet4.htm A method for investigating the growth of pollen tubes. IGCSE BIOLOGY 0610 SCHEME OF WORK III 1.2.1 Discuss the implications to a species of self pollination and cross pollination. III 2 Describe the environmental conditions affecting germination. III 2 Define growth in terms of increase in dry mass. Define development in terms of increase in complexity. This topic is difficult to deal with at this level, especially as genetics and evolution are yet to be covered. However, extension candidates should be able to consider them in terms of the degree of variation amongst offspring, and begin to think about the effects this might have on populations. Ensure that the emphasis is on the species itself, not on advantages or disadvantages to farmers or gardeners who grow the plants. This is an excellent opportunity for candidates to design a simple investigation for themselves. Note that most of the seeds that are used in laboratories are derived from crop plants, and these do not normally require light for germination. However, light is commonly required for the germination of the seeds of other plants. The germination and subsequent growth of seedlings can be used as an illustration of growth and development, and students could carry out simple investigations into this. Investigating seed germination http://wwwsaps.plantsci.cam.ac.uk/work sheets/ssheets/ssheet5.htm Morphology and growth of the rice plant http://www.riceweb.org/Plant. htm IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 7: Human Reproduction Recommended Prior Knowledge: Students should have knowledge of the basic principles of sexual reproduction, which has been covered in Unit 6. They should also understand the nature of hormones, dealt with in Unit 5. Context: this Unit builds on the work on sexual reproduction covered in the early part of Unit 6. This Unit and Unit 6 lay the foundations for the study of genetics, to be covered in Unit 8. Outline: This Unit considers the biological aspects of human reproduction, and also provides the opportunity to discuss some of the social and ethical issues associated with birth control, artificial insemination and fertility drugs. It is a relatively short Unit, with no real opportunities for practical work. Some teachers may therefore like to combine it with Unit 6, or with Unit 8. III 1.2 .2 III 1.3 III 1.3 III 1.2 .2 Learning Outcomes Describe the structure and function of human male and female reproductive systems, including the menstrual cycle. Describe the roles of testosterone and oestrogen in the development and regulation of secondary sexual characteristics at puberty. Describe the sites of production and the roles of oestrogen and progesterone in the menstrual cycle. Describe sexual intercourse, fertilisation and implantation. Suggested Teaching Activities Diagrams and models can be used to illustrate the structure of the male and female reproductive systems. Students should be able to interpret either front or side views. For Core students, there is no need to know anything about the hormonal control of the menstrual cycle. The general characteristics of hormones will already have been covered, and here two others are introduced. Extension candidates should be aware of the cyclical secretion of oestrogen and progesterone from the ovary. They do not need to know any detail of the development of follicles within the ovary, nor the roles of FSH and LH. Students will already have met the idea of gametes and fertilisation, and these ideas should be revisited here before considering how they occur in humans. Online Resources Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK III 1.2 .1 Describe the development of the foetus in terms of placenta, maternal and foetal blood supplies and exchange of materials. Describe ante-natal care in terms of dietary requirements and maintaining good health birth. III 1.2 .2 Indicate the functions of the amniotic sac and amniotic fluid. III 1.3 Describe the sites of production and the roles of oestrogen and progesterone in pregnancy. Describe the advantages of breast feeding compared with bottle feeding. III 1.2 .2 III 1.4 Discuss the social aspects of artificial insemination and the use of hormones in fertility drugs. Diagrams should be drawn to show the relationship between the foetus, umbilical cord and placenta. The large surface area of the placenta villi can be compared to that of the lungs or small intestine; in each case, the large surface area helps to maximise the rate of exchange across it. Make sure that students understand that maternal and foetal blood do not mix. They should be precise in naming materials that cross the placenta, for example mentioning glucose and amino acids rather than 'nutrients', and also understand that they may cross by diffusion. The effects of smoking on health, first met in Unit 4, can be looked at again here in relation to pregnancy. The idea of protection of the embryo must be emphasised. The amniotic fluid produces a cushioning effect from physical damage. The amniotic sac provides protection against infection. (Details of the composition of the fluid are not required) This can be linked with the roles of these hormones in the menstrual cycle. This topic can be dealt with through discussion, perhaps after students have done a little research of their own. The biological advantages of breast-feeding are incontrovertible, but students should also be aware of social or other reasons why some mothers find this difficult and prefer to use formula milk. A simple factual treatment of what artificial insemination is, and the use of fertility drugs, will be required before students can discuss the social and ethical issues Benefits of breast feeding http://www.cyberparent.com/ bfeed2/ IGCSE BIOLOGY 0610 SCHEME OF WORK III 1.4 Name and describe the following methods of birth control: natural, chemical, mechanical and surgical III 1.5 Describe the symptoms, signs, effects and treatment of gonorrhoea. Describe the methods of transmission of human immunodeficiency virus (HIV) and the ways in which it can be prevented from spreading. associated with it. These issues regularly find their way into the news, and it would be useful to collect a range of articles from newspapers and magazines that could form the basis for discussion. A simple description of the biological basis of the different types of birth control is required. Students should also understand the relative effectiveness of each, and may want to discuss the ways in which religious or cultural beliefs can affect their use. The advantages of condoms in reducing the risk of transmitting diseases should also be considered. Gonorrhoea is used as an example of a relatively common sexually-transmitted disease caused by a bacterium, readily treated with antibiotics. HIV, on the other hand, is caused by a virus, and as yet no cure is available. Although no detail is expected of the symptoms of AIDS, it could be useful to deal with these briefly, with reference back to the functions of white blood cells in Unit 4. IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 8: Inheritance and Evolution Recommended Prior Knowledge: Knowledge Basic knowledge of cell structure is required, and also an understanding of the processes involved in sexual reproduction. Context: This Unit builds on the topic of sexual reproduction, covered in Units 6 and 7. Outline: The Unit begins with the introduction of several new terms, before moving on to genetics and inheritance. Variation, affected by both genotype and phenotype, is investigated, before considering the ideas of natural selection and evolution. III 3.1 III Learning Outcomes Define the following terms: chromosome; gene; allele; haploid and diploid nuclei Define the following terms: genotype; Suggested Teaching Activities Students should know that a chromosome is a length of DNA, and that each chromosome carries a large number of genes. They may be interested to discuss the human genome project, which is mapping all the genes on the human chromosomes. They may already have met the terms haploid and diploid when considering the processes involved in sexual reproduction. A haploid cell is one with a single set of chromosomes (for example a gamete) while a diploid cell has two complete sets. Meiosis produces haploid cells from diploid. It is important to use the terms 'gene' and 'allele' correctly right from the start. If this is done, students find them easy to use, and there is no reason for confusion! At IGCSE level, it is enough to define a gene as a length of DNA giving instructions for a certain characteristic. However, you may prefer to say that a gene carries instructions for making a particular protein. An allele is a variety of a gene, and many genes have many different alleles. Online Resources The Human Genome Project http://www.genome.gov/page .cfm?pageID=10001694 It is best to consider the meanings of these Genotype and phenotype Introduction to chromosomes http://gslc.genetics.utah.edu/ units/basics/tour/ Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK 3.4 phenotype; homozygous; heterozygous; dominant; recessive terms before thinking about inheritance. They can best be illustrated and explained with reference to a particular characteristic. Choose something simple, and that is likely to appeal to students, such as coat colour of an animal. The example does not have to be real. It should involve a gene with two alleles, one dominant and one recessive. Students should learn that one letter is used to represent these alleles, with an upper case letter for the dominant allele and a lower case letter for the recessive allele. They will already know that most cells are diploid, so should be able to understand that they therefore carry two copies of each gene. They can work out for themselves the three possible combinations of alleles, and think about what colours will result from them. Hence the terms genotype, phenotype, homozygous and heterozygous can be introduced and defined. It is a good idea to spend some time with such examples, and ensure that students are thoroughly confident using the terminology, before beginning to think about how inheritance occurs. http://www.brooklyn.cuny.edu /bc/ahp/BioInfo/GP/Definition .html III 3.4 Calculate and predict the results of monohybrid crosses involving 1 : 1 and 3 One or more of the examples used to illustrate the meanings of the above terms The genetics of PKU http://www.ess.sunysb.edu/tr IGCSE BIOLOGY 0610 SCHEME OF WORK : 1 ratios can now be taken further. Use correctly drawn genetic diagrams right from the start, and do not let students take short cuts! The correct way to set out a genetic cross is shown on page 20 of the syllabus. Students should be reminded that gametes are haploid cells, and therefore carry only one copy of each gene. They can be asked to work out what kind of gametes will be produced by organisms with a range of different genotypes. It is good practice, and avoids confusion, if a circle is drawn around each gamete genotype when writing out a genetic cross. Discourage students from automatically writing down two gametes from each parent. This is only necessary if the parent is heterozygous and producing two different kinds of gamete. If it is homozygous, then only one kind of gamete is made, and only one needs to be written down. Next, they can be introduced to the idea of random fertilisation, in which any kind of gamete from the male parent can fuse with any kind of gamete from the female parent. The offspring now have two copies of each gene again. Drawing lines from gamete to gamete often causes errors to be introduced, and a simple diamond or square, with gametes along the sides and offspring genotypes in the boxes, is more likely to avoid errors. Ensure that students understand that what they have worked out is the probability of particular genotypes being produced. The fact that, for example, four different genotypes are present amongst the offspring does not mean that the parents acy/genetics.html Inheritance patterns in monogenic disorders http://www.gig.org.uk/educati on2.htm IGCSE BIOLOGY 0610 SCHEME OF WORK III 3.4 Explain codominance and inheritance of A, B, AB, O blood groups (IA, IB and 1O). III 3.1 Describe the inheritance of sex in humans (XX, XY). III 3.5 Describe continuous and discontinuous variation as influenced by the environment and genes, illustrated by height and A, B, AB and 0 blood groups in humans. will have four children! Codominance is, in many ways, easier to deal with than dominance. It is easy for students to imagine that a combination of two different alleles will produce an effect that is a mixture of both of them. The correct use of symbols should be encouraged; where codominance exists, the gene is shown with an upper case letter, with superscripts to represent the different alleles. The genetics of the A, B, AB and O blood groups is a good example of codominance, but it is also more complex than what has gone before because there are now three different alleles of the gene to consider, rather than just two. It is therefore helpful to write down a list of all the possible genotypes and the resulting phenotypes before attempting to deal with any crosses. Ensure that the correct symbols, as used in the syllabus, are automatically used by students. They should not take the easy way out by writing A and B instead of IA and IB. The inheritance of sex can be dealt with in the same way as the inheritance of genes, but this time the symbols X and Y are used to indicate whole chromosomes, not alleles of a gene. Students should be able to draw genetic crosses to show that you would expect equal numbers of males and females to be born. Extension students will already be familiar with the A, B, AB and O blood groups, but these will need introducing for Core students. They are a good example of discontinuous variation. Students can draw bar charts to show the relative proportions Coat colour in Great Danes http://www.greatdanerescuei nc.com/PrimaryColor.html ABO genetics http://www.people.virginia.ed u/~rjh9u/abo.html Variation – continuous and discontinuous http://www.bbc.co.uk/scotlan d/revision/biology/inheritance /variation_and_genetics_and _society_rev.shtml IGCSE BIOLOGY 0610 SCHEME OF WORK of people with these four blood groups. They will not find it difficult to understand that everyone fits into one of these four categories, with no in-betweens, and this is therefore an example of discontinuous variation. They could then be asked to think of other examples of discontinuous variation, and may think of gender. Continuous variation can be illustrated by almost anything that is measurable on a human - height, length of middle finger or wrist circumference will each give a good range of results and not cause any embarrassment! Leaves or other plant material can also be used to generate a range of results. Students will realise that they are dealing with something that behaves differently from blood groups; now there are no clear-cut categories, but a whole range of values. To show them graphically, they will need to decide on 6 or 7 ranges and then draw up a tally chart to show how many values fit into each range. These can then be plotted on a histogram. A common misconception is that 'continuous variation' means something that changes through your life. Although this is true of the measurements students are likely to have made to illustrate this, it is not the correct meaning of the term. Use other features, such as hair or eye colour, to emphasise the real meaning of continuous variation. Students should be able to work out for themselves that, while discontinuous variation is caused purely by genes, continuous variation often involves influence by the environment as well. IGCSE BIOLOGY 0610 SCHEME OF WORK III 3.5 Define mutation. Describe mutation as a source of variation, as shown by Down's syndrome. Outline the effects of radiation and chemicals on the rate of mutation. III 3.5 Describe sickle cell anaemia and explain its incidence in relation to that of malaria. Mutation can be defined as an unpredictable change in the DNA content of a cell. It can affect a single gene, or whole chromosomes, and can happen at any stage, not only during cell division. Ionising radiation and mustard gas can be given as examples of factors that may cause mutations. Down's syndrome is used to illustrate a mutation that occurs during cell division, and that affects the number of chromosomes in a cell. Students could look at karyotypes of people with Down's syndrome, and compare them with karyotypes of males and females with the normal number of chromosomes. Sickle cell anaemia can be explained as the result of a mutation in the gene that codes for the production of haemoglobin. The effects of this on the carriage of oxygen, and the consequences for respiring cells in body tissues, can be discussed. Its inheritance can also be considered. Students will need to know a little about malaria. They can then look at maps showing the distribution of malaria and of sickle cell anaemia, and begin to think of why these should be so similar. The story is not a simple one, and will give plenty of food for thought for Extension students. It is a good way to introduce the ideas of selection pressures, and natural selection. Down’s syndrome as an example of mutation http://www.bbc.co.uk/scotlan d/revision/biology/inheritance /variation_and_genetics_and _society_rev.shtml Sickle cell disease http://www.cuhk.edu.hk/med/ paf/slides/hematolo/xv19.htm Inheritance of sickle cell anaemia http://www.sicklecellsociety.o rg/education.htm IGCSE BIOLOGY 0610 SCHEME OF WORK III 3.6 Describe the role of artificial selection in the production of varieties of animals and plants with increased economic importance. III 3.6 Define natural selection as the passing on of genes by the best adapted organisms Assess the importance of natural selection as a possible mechanism for evolution Describe variation and state that competition leads to differential survival of, and reproduction by, those organisms best fitted to the environment Students are already aware that variation occurs within populations of organisms, and they will not find it difficult to think how humans may choose a particular variety of an animal or plant, and use this to breed from. Real or imaginary examples can be used to illustrate this. It should be made clear that this selection needs to continue for many generations, and does not produce immediate results. If students have already considered the sickle cell anaemia story, they will already have thought about the ideas of differential survival and selection. Here, they can think a little more widely, perhaps using imaginary examples to think about how competition for scarce resources could lead to some individuals being more likely to survive and breed than others. These will pass on their alleles to their offspring, so that the alleles that confer the advantageous characteristics gradually become more common. Over time, this could lead to a change in the overall characteristics of the species. Simulated evolution http://home.pacbell.net/smax/scott/simevol.html III 3.6 Describe the development of strains of antibiotic resistant bacteria as an example of natural selection The development of antibiotic-resistant strains of bacteria makes a good example to illustrate the ideas in the previous section. Antibiotic resistance http://www.hpa.org.uk/infecti ons/topics_az/wfhfactsheets/ WFHantib.htm III 3.7 Define genetic engineering as taking a gene from one species and putting it into another species Use simple diagrams of bacteria containing circular DNA to show how a section of human DNA can be inserted into the bacterial DNA. Explain that DNA can be cut in certain places using different restriction enzymes to select the correct gene. If the same Description of human insulin production http://www.tiscali.co.uk/refere nce/encyclopaedia/hutchinso n/m0007839.html Explain why, and outline how, human insulin genes were put in to bacteria using genetic engineering IGCSE BIOLOGY 0610 SCHEME OF WORK restriction enzyme is used to cut the bacterial DNA then the ends of the human and bacterial DNA will stick together. IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 9: Organisms and Environment Recommended Prior Knowledge: Students should have knowledge of photosynthesis and respiration, and understand something of energy transfers. They should know the elements from which biological molecules are made, in order to understand nutrient cycles. Context: This Unit brings together ideas from several earlier Units and lays the foundations for Unit 10. Outline: It is hoped that students will be able to visit a local habitat, even if only in the school grounds, during this Unit. The Unit begins with the naming and classification of living organisms, with some thought being given to their adaptations to their environment. Keys are used to help to identify them. The flow of energy and cycling of nutrients through ecosystems is covered. This Unit sets the scene for a consideration of how human activities can affect ecosystems, in Unit 10. I2 Learning Outcomes Define and describe the binomial system of naming species. I2 Classify the five main classes of vertebrates using visible, external characteristic features only. I2 List the main features used in the classification of the following groups: flowering plants (monocotyledons and dicotyledons), arthropods (insects, crustaceans, arachnids and myriapods), annelids, nematodes and molluscs, using visible, external characteristic features only. Suggested Teaching Activities Students will probably already know a few binomials, such as Homo sapiens, and this makes a good starting point for discussing why Latin names are used and how they are constructed. Take care that the name of the genus is always given a capital letter, and that of the species a lower case letter. Photographs or specimens of the five groups of vertebrates can be used to illustrate their external features. Students could be given a blank chart to complete, observing and recording for themselves relevant features for each group, such as body covering. A definitive table can then be built up from their observations. A similar approach can be taken here. All of these organisms, with the exception of nematodes, can be easily observed in almost any habitat. It is excellent if students can observe them within an ecosystem, and not just as pictures or preserved specimens. Students should be able to describe features that are characteristic of all arthropods, and also those that distinguish each of the four arthropod Online Resources Species diversity http://www.seaworld.org/infoboo ks/Biodiversity/speciesbio.html Photographs and descriptions of a range of mammals, reptiles, amphibians and fish. Monocots vs.dicots http://www.csdl.tamu.edu/FLOR A/201Manhart/mono.vs.di/mono svsdi.html Understanding arthropod classification and identification http://members.aol.com/YESed u/arthrocl.html Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK I2 List the main features used in the classification of the following groups: viruses, bacteria, fungi, and their adaptation to the environment, as appropriate. I3 Use simple dichotomous keys based on easily identifiable features. IV 1 State that the Sun is the principal source of energy input to biological systems. Describe the non-cyclical nature of energy flow. groups listed. This is also an excellent opportunity to consider how particular animals are adapted to their environment. Adaptations of plants to different environments have already been considered in Unit 3, so it would be sensible to concentrate on animal adaptations here. Viruses and bacteria are too small for students to be able to examine real specimens, so they will need to use photographs and diagrams. Fungi, however, are easily visible. Note that here all features that enable the classification of these groups are required, not just externally visible ones. Teachers will need to devise or select simple keys that can be used to identify a range of specimens available to students. It is strongly recommended that this is done with living specimens within a habitat that the students can visit - for example, identifying trees in the school grounds, using keys to their leaves. Extension students could also try devising dichotomous keys of their own. Having looked at the range of different types of organisms that live in a habitat, students now consider the relationships between them. The concept of energy is not an easy one, and students who have not met with it in either physics or chemistry courses will need an opportunity to think about what it means. Photosynthesis and respiration have already been dealt with, so what is needed here is a link to be made between the two, Introduction to the annelida http://www.ucmp.berkeley.edu/a nnelida/annelida.html The Virtual Virus Experience http://library.thinkquest.org/1337 3/intro/intro.htm IGCSE BIOLOGY 0610 SCHEME OF WORK IV 2 Define the following: food chain; food web; producer; consumer, herbivore, carnivore, decomposer; ecosystem, trophic level IV 2 Describe energy losses between trophic levels and the advantages of short food chains. Describe and interpret pyramids of biomass, numbers and energy. IV 2 Recognise that there is an increased plus the idea that animals obtain energyrich nutrients from plants. If students have an opportunity to visit a habitat, even if only in the school grounds, then they should be able to construct food chains and food webs for themselves. Emphasise that the arrows in a food chain represent the direction of energy flow. Definitions of each of these terms can be built up once students are comfortable with the concept of food chains. Students who have studied physics may already understand that energy transfers are never 100% efficient, and that some energy is always lost as heat when energy is transferred from one form to another. They will best understand the concept if encouraged to think about a particular example, such as energy transfer from grass in a field and cattle that are eating it. Once energy losses are understood, it should become apparent that food chains cannot go on for ever. Pyramids of numbers, biomass and energy can be drawn for particular food chains or webs. Students can think of them as a kind of graph, in which the areas of the boxes represent values for whatever is being plotted. The concepts being dealt with here are not easy for most students to comprehend, and adequate time should be allocated to ensure that they are not rushed in absorbing these ideas. Extension students can now take the ideas Trophic pyramids and food webs http://www.geog.ouc.bc.ca/phys geog/contents/9o.html IGCSE BIOLOGY 0610 SCHEME OF WORK efficiency in supplying green plants as human food and that there is relative inefficiency, in terms of energy loss, of feeding crop plants to animals. IV 3 Describe the water cycle. IV 3 Describe the carbon cycle. IV 3 Discuss the effects of combustion of fossil fuels and cutting down of forests on the balance between oxygen and carbon dioxide. IV 3 Describe the nitrogen cycle in terms of the role of micro-organisms in providing usable nitrogen-containing substances by decomposition and by nitrogen fixation in roots; the absorption of these substances by plants and their conversion to protein, followed by passage through food chains, death, decay and the return of nitrogen to the soil or the atmosphere (Names of of energy flow and losses between trophic levels a little further, and think of their implications for human populations. They may also like to consider why, if it is inefficient in terms of energy, so many human populations use animals for food. This is likely to be revision for many students. The roles of trees and other plants in returning water vapour to the air, through transpiration, should be emphasised. Rather than simply presenting students with a complete diagram of a carbon cycle, it can be very useful to build it up together. They will know enough of photosynthesis, respiration and combustion to be able to think of most of the steps that should be included. Human influences on the carbon cycle are now considered. Fossil fuels and trees contain huge amounts of carbon, and when burnt this is released into the air. Students will probably already be aware that increased amounts of carbon dioxide in the atmosphere are likely to lead to global warming. Take care to avoid confusion between this and the damage to the ozone layer - a common source of confusion. The nitrogen cycle is considerably more difficult for students to understand than the carbon cycle. It is important that they understand the different forms in which nitrogen occurs – as nitrogen gas in the air, nitrate ions in the soil and proteins in animals and plants. They also need to realise that nitrogen gas is unreactive, and must be converted to something more reactive before plants can make use of it. The water cycle http://wwwk12.atmos.washingto n.edu/k12/pilot/water_cycle/grab ber2.html IGCSE BIOLOGY 0610 SCHEME OF WORK individual bacteria are not required). Avoid using the term 'nitrogen' alone, always specifying the particular compound that is being discussed. IGCSE BIOLOGY 0610 SCHEME OF WORK UNIT 10: Human influences on the environment. Recommended Prior Knowledge: Students should have covered Unit 9 before beginning this Unit. Context: This Unit builds on ideas studies in Unit 9, and brings together knowledge from many other areas of the syllabus. Outline: General features of population growth are first considered, before looking in particular at problems associated with human population growth. A number of different effects of the growing human population on the environment are then considered. Some of these are complex issues, with no straightforward answers, and students should be encouraged to discuss and debate them. IV 4 Learning Outcomes State the factors affecting the rate of population growth, and describe their importance (e.g. food, supply, predation and disease) Identify the phases of a sigmoid curve of population growth resulting from the action of a limiting factor. Explain the factors that lead to the lag phase, exponential phase and stationary phase in the sigmoid curve of population growth. IV 4 Describe the increase in population size in the absence of limiting factors (human population growth) and the social implications of current human survival rate interpret graphs and diagrams of human population growth. Suggested Teaching Activities The term 'population' will need to be defined before thinking about how populations grow. Ideas about how populations grow can be built up by discussion, concentrating on examples that are likely to be familiar to students – for example they could imagine what might happen if a few rabbits were introduced onto an island where none have previously existed. Simple sketch graphs should be drawn to illustrate population growth, and possible factors that might cause a levelling off in population growth can be considered. The ideas developed in the previous section are now applied to human population growth. Graphs showing how the human population has changed in the past, and predictions for the future should be drawn. Students could also be introduced to population pyramids and their interpretation. They should discuss the possible implications of continued growth of the world human population, if possible with reference to particular examples, collected from newspapers and other sources of up-to-date information and data. Online Resources Other resources IGCSE BIOLOGY 0610 SCHEME OF WORK IV 5.1 Discuss, using suitable examples, ways in which the use of modern technology has resulted in increased food production. IV 5.1 Describe the undesirable effects of deforestation. IV 5.1 Describe the over-use of fertilisers on the land. IV 5.2 Describe the undesirable effects of water pollution by sewage and chemical waste, air pollution by sulphur dioxide and pollution due to pesticides and herbicides and nuclear fall-out. Where possible, this should be related both to the students' own country, and also to other countries in the world. Ideas to consider are the introduction of machinery (tractors to replace draught animals, for example), and the increasing use of pesticides and fertilisers, as well as the breeding of new high-yielding crop varieties. At least one specific example should be looked at in some detail. Deforestation may already have been considered in relation to the carbon cycle, and now more wide-ranging effects can be considered, such as loss of habitat and increased soil erosion and flooding. Again, it is a good idea to try to introduce at least one specific example, as well as discussing the problems in general. The use of fertilisers containing nitrate can be concentrated on here, and related back to the nitrogen cycle (dealt with in Unit 9). Ensure that students realise that both organic (for example manure) and inorganic fertilisers can cause problems, but do avoid creating a completely negative attitude towards farmers. Leaching into waterways, and subsequent eutrophication, should be described and explained. Pollution of waterways by raw (untreated) sewage can be considered to cause the same problems as fertilisers, plus the risks to health from water-borne pathogens (e.g. cholera). Problems caused by pesticides could be dealt with by considering a particular example, e.g. DDT, and the Two sites explaining what is being done in the UK to reduce pollution from fertilisers: Nitrate Vulnerable Zones http://www.environmentagenc y.gov.uk/yourenv/eff/water/210 440/ Nitrate Sensitive Areas http://www.defra.gov.uk/news/ newsrel/1998/980122a.htm DDT a banned insecticide http://www.chem.ox.ac.uk/it_le ctures/chemistry/mom/ddt/ddt. html DDT - a replacement is necessary before a ban IGCSE BIOLOGY 0610 SCHEME OF WORK debate for and against its continued use in countries where malaria is a major problem. This example demonstrates that these issues are not simply matters of right and wrong, but involve complex evaluation and careful decision making. Make sure that students realise that not all pesticides are long-lasting and accumulate up food chains. Non-biodegradable materials will be detrimental to the environment if they are put in land fill sites. They will produce air pollution if they are burnt in an incinerator. The environmentally friendly option is to recycle materials such as paper, glass, metal etc. This reduces environmental pollution and saves energy in production costs. Students should understand that acid rain is caused by sulphur dioxide (released from the burning of oil and coal, for example in power stations) and nitrogen oxides (present, for example, in car exhausts. They should know something of the biological effects of acid rain. http://www.malaria.org/teachin gmodules/ddt.html IV 5.2 Assess the significance of nonbiodegradable plastics and other materials used in the manufacturing industry. IV 5.2 Discuss the causes and apparent effects on the environment of acid rain and the measures which might be taken to reduce its incidence. IV 5.3 Describe the need for conservation of species and their habitats and of natural resources. It is best to look at some specific examples here, either relating to the students' home country, or of international importance (such as tigers in India, elephants in Africa or orang-utans in Borneo). Tigers in the wild http://www.panda.org/about_w wf/what_we_do/species/show species.cfm?SID=25&LID=1& FH=E IV 5.3 Describe the principle of recycling of materials including sewage (water) and paper. Students should learn how sewage is dealt with in their own local area, and there may be an opportunity to visit a sewage treatment plant, or at the very least to obtain information from the water company responsible for this. Plastics recycling http://www.plasticsresource.co m/ http://www.alupro.org.uk/ Facts and information about recycling and environmental projects or schools. FAQ's on acid rain http://www.ns.ec.gc.ca/aeb/ss d/acid/acidfaq.html