Psychosis: descriptive psychopathology Descriptive Psychopathology of Psychosis Adrian Lloyd • • • • • Language/speech Thought Perception Movement Disorders of self Language & Speech Language & Speech • Revise Thought/Language from psychopathology covered in affective disorders • Relationship of thought & language • Disorders of language & speech • Psychotic language & speech disorders Relationship of thought & language Thought Language 1 Thought & language disturbance e.g. Flight of ideas Derailment Loose associations Clang associations Retardation Circumstantiality Overinclusiveness Fusion Thought block Rhymes Perseveration Concrete thinking Thought Language Speech disturbance • Mutism (all major s, organic disorders) • Prosody & volume changes • Unintelligible speech – Paragrammatism / incoherent syntax (>>> ‘word salad’) – Neoligisms – Stock words/phrases private symbolism – Cryptolalia/graphia Speech/language disorders of localising value • Sensory dysphasias Speech/language disorders of localising value • Motor dysphasias – Pure word deafness – Pure word blindness – 1º sensory dysphasia – (Nominal dysphasia) – Jargon aphasia – Pure word dumbness – Pure agraphia – 1º motor dysphasia – Alexia with agraphia – Isolated speech area Generation of language/speech Speech areas • Language development (phonemes - categorisation) Organic speech disorders further reading: Strub RL & Black WF, The mental status Examination in neurology; FA Davis AF B BA 44 W BA 22 Lishman WA, Organic psychiatry; Blackwell • Memory stores (verbs: frontal; nouns: temporal) • Word generation (syllable production & connection: posterior parietal) • • • • • • Grammar / syntax (revolves around verbs; ?frontal) Prosody (largely R hemisphere) Short term memory (for understanding of discourse) Semantic processing (largely R hemisphere) Phonation (motor) Articulation (motor) 2 Assessment of speech • • • • • • • • • • • • Phonation Articulation Quantity Rate Fluency Spontaneity Prososdy Volume Vocabulary Syntax Cohesive ties Proposition Language in affective psychoses Mania – Pressured ( quantity, rate & spontaneity), loud, cohesive links, clang associations (terminal syllable) Depression – quantity, rate, volume, spontaneity, prosody, retardation Language in schizophrenia •Thought disorder as expressed in language – Akataphasia – Loss of continuity of associations – Asyndesis – Metonyms – Over-inclusive thinking – Concrete thinking – Poverty of speech (thought) – – – – – – – Neologism Block Derailment Loss of goal Tangentiality Illogicality defect of deductive reasoning • empty speech • alogia • verbigeration Language in schizophrenia •Altered / misused words, phrases & grammar – – – – Stock words/phrases Semantic halo neoligism intrusion of dominant meanings – Clang associations (initial syllable) – Repetitive speech (intrusion of associations) – – – – – – – – Alogia Paralogia Paraphasia Literal paraphasia Verbal paraphasia Agrammatism Telegramese (loss of adverbs) Paragrammatism • Syntax preserved long after word use disturbance occurs • Sz speech is less predictable than normal speech Assessment of thought • Form – Quantity/rate – Fluency/associations – Judgement/reasoning Thought • • • • Delusion Overvalued Obsessional Normal – Possession • Passivity – Themes • • • • • Self-referent Depressive/nihilistic Grandiose Persecutory Religious • Content – Specific ideas of the subject • eg – – – – – Al Qaeda are after me I am God I receive radio waves The world is in ruin Trees speak to me – Mood congruence? – Ideas of harm to others? 3 Form: Normal thought Form: Flight of ideas •Rate •Loss of determining tendency Initial thought Goal •Individual associations can be recognised (but may be unusual) Determining tendency After Sims Form: Retardation After Sims Form: Circumstantiality Goal Goal •Rate slowed •Determining T. intact •Fewer associations •Rate normal •Determining T. intact •lots of unnecessary detail After Sims Form: Derailment / knight’s move / entgleisen •Loss of understandable associations After Sims Form: Derailment / knight’s move / entgleisen •Loss of understandable associations After Sims After Sims 4 Form: Thought block / entgleiten Fusion / verschmelzung Unexpected breaking off of chain of thought Bringing together of various themes – conversation difficult to follow After Sims After Sims Judgement / reasoning Form: Thought block / entgleiten • Delusion – Unshakeable false belief out of keeping with social/cultural background • Primary: un-understandable • Secondary: evolve to explain other experiences (voices, thought block etc) • Overvalued idea (“as if” quality) – Challengeable; open to reasoning but cannot be ignored • Obsessional thought – Own, recognised as illogical, resisted, intrusive Unexpected breaking off of chain of thought After Sims Other aspects of thought form • Passivity: Thoughts are not my own / are controlled by something other than me • Can also apply to interpretation of actions/behaviour • • • • Self referent ideas (= ‘paranoid’) Grandiosity Nihilism etc Can be delusional or overvalued 5 Perception Perception Perception • Revise Perception from psychopathology covered in affective disorders Normal •Sensory perception •Imagery •Eidetic Imagery • Perception in psychosis False Perceptions Illusions Sensory Distortions in Psychosis • intensity • mania, drug-induced, epilepsy • intensity • depression • micropsia/macropsia/dysmaegalopsia /metamporphopsia(paraprosipia: faces) Pseudohallucinations Abnormal Sensory Distortions •Intensity •Size •Colour Hallucinations False Perceptions in Psychosis • Hallucinations • normal perception, can percieve > 1 at once • may not have corroborative evidence, may be explained delusionally (as may the fact that others do not have access to the experience) • Organic states, epilepsy, Sz (rare), drug-induced • Split perception • organic states, Sz 6 Hallucinations • Auditory Hallucinations • Visual • Can be difficult to differentiate from other visual abnormalities • Organic rather than ‘functional’ psychoses – elementary • noises: usually in organic states » TLE, delerium, dementias, encephalopthies etc. – complex • Drug-induced • Voices » mescaline, LSD, solvents, mushrooms. – organic states (including alcohol-inuced): simple words – Affective psychoses & Sz - simple words, complex speech (2nd &/or 3rd* pers. Gedenkenlautwerden*, running commentary*) – behaviour observed 2º to hallucination » distraction, verbal responses, actions ?vocalisation (* = 1st rank) • may have affective associations - e.g. DTs • Association with other visual abnormalities » e.g. cortical blindness, hemianopias, dyslexia etc. • Sz: rare » cf vis. pseudohallucinations related to auditory hallns. » Scenic vis. hallns. in oneroid states. • Charles Bonnet syndrome • Autoscopic visual hallucination. Hallucinations • Bodily sensation – Superficial • Thermic • Haptic • Hygric – Kinaesthetic • Joint / muscle sensation – Visceral Hallucinations • Olfactory / gustatory Frequently delusionally interpreted • Often as passivity • Common in Sz – With both hallucinatory & delusional components •Affective psychoses •Drug-induced / withdrawal states • Inner organs False Perceptions in Psychosis – Epilpsy (esp TLE) – Sz – Other organic pathology – Affective psychoses • (mood congruence) Hallucinations • Pseudohallucinations – Nature • • • • • Visual, auditory, tactile Involuntary Figurative Not as real as normal perception Internal subjective space (Kandinsky/Jaspers) – Occur in many psychiatric (psychotic & nonpsychotic) disorders and in non-pathological states • No diagnostic significance May self-referentially interpreted – Strong link with memory v • Persecutory • Mood congruent Distinguish from other factors relating to smell/tatse • Medication • Overvalued normal odours • Delusion without hallucination PseudoHallucin’ns v Fantasy External space Internal space Internal space Unwilled Unwilled Willed Vivid/well defined Vivid/well defd. indef/incomplete Concrete/real Not completely real; “inner eye” Pictorial quality ? Could not do so Could exist in other sens. Modality Independent of observer Dependent Dependent 7 Other specific sensory experiences • Autoscopy – Visual halln or pseudohalln • Extracampine hallucination – a perception outside normal sensory field • Hypnagogic/Hypnopompic hallucinations – falling asleep / waking respectively – in narcolepsy, cataplexy & sleep paralysis • Functional hallucination – halln provoked by an external stimulus • Reflex hallucination – hallucinatory synaesthesia • Abnormal imagery – reduced or abnormally vivid • Abnormal perception in sensory deprivation Movement disorders • Classification » none is all-encompassing » none are mutually exclusive Movement Disorders – MSE – Disorder-based – Aetiological – Form of movement • Checklists Classification - MSE • Appearance – facial expression – posture • Behaviour – reflective of mood state – independent of mood – ‘bizarre’ Classification - disorder-based • Motor symptoms characteristic of – – – – – – – – depression mania schizophrenia Huntington’s OCD Hysteria Dementias etc etc etc Huge overlap, v non-specific as regards description of movement 8 Classification - aetiological Classification - form agitation organic cerebellar EPS 2 º to Sx of disorder myoclonus Drugs 1º Sx of disorder /motor retardation catatonia tics Response to hall’ns /dell’ns fear & distress chorea conversion EPSE • Adaptive movements • Non-adaptive movements – spontaneous – induced • Speech • Posture • Complex behavioural patterns » From Sims (sx in the mind) + Hamilton M (Ed.) Fish’s Clinical psychopathology 2nd edition 1985. Wright » For summary see Buckley/Bird & Harrison; Examination notes in psychiatry. Butterworth-Heinemann intoxication akathisia tremor Form – adaptive movements • Expressive behaviour Form – non-adaptive movements • Spontaneous – Facial expression, gesturing • Reactive behaviour – e.g. startle ( in PTSD/anx; in depn, Sz –ve Sx) • Goal directed movements – e.g. tics, tremor, EPS, conversion, choreo-athetosis, dyskinesias, dystonias, stereotypies (Can increase in anxiety) • Induced – Mannerisms – e.g. in catatonia – Abnormal, repetitive goal directed movements – Obstruction (in catatonia) – automatic obedience, mitgehen, echopraxia, echolalia, negativism, perseveration, etc. – Stopping in mid-goal directed movement » ? Motor equivalent of thought block Form – motor speech disturbances • Attitude – negativism, responding to voices, etc. • Flow – Mutism, slowed, staccato, pressure Tic v stereotypy v mannerism • Mannerisms – Stress, inflection, rhythm, pronunciation etc • Stereotypies – Words & phrases used repeatedly • Perseveration – of words or themes • Echolalia – Speech equivalent of echopraxia 9 Form - patterns of complex behaviour Form – posture Abnormal psychic events • Catatonic posturing Subjective • including waxy flexibility Consequent behaviour experience • Postural mannerisms • ‘Sagging’ in depression • ‘Upright/tense’ in anxiety = Phenomenology = Observation Assumption Goal directed OCD – rituals hebephrenic ‘silliness’ mania response to psychotic Sx Make sure you know these!! • Agitation • Retardation (psychomotor) • Hyperactivity • Hyperkinesis • Mannerism • Stereotypy • Dystonia • Dyskinesia • Chorea • Perseveration • • • • • • • • • • • Athetosis Myoclonus Ataxia EPS / EPSE Tremors Conversion (Dissociation) Tics Stupor Akinesis Akathisia Non-goal directed Stupor catatonia hysteria organic etc. excitement catatonia anxiety mania etc. Make sure you know these!! – Excessive opposition • Catatonia • • • • – Psychological pillow – Posturing – Excessive compliance • • • • • • • Mitmachen Mitgehen Automatic obedience Echopraxia Echolalia Forced grasping Advertance – – – – – Gegenhalten Negativism Aversion mutism Ambitendency Schnauzkrampf Stupor/akinetic mutism Waxy flexibility Obstruction ‘Self’ Social setting Body Schema Disorders of Self Perceived body Self-concept 1 Body concept Self-concept 2 Body image 10 Self awareness/experience • Awareness of existence & activity of the self • Mental • Physical Disorders of self • Existence & activity: (possession of activity, perception, movement, mental functions, cognition, emotions etc) • changed experience of activity: depersonalization (this is not psychotic) • Awareness of being a unity at any given point of time • Awareness of continuity of identity over time • Awareness of the boundaries of self Jaspers. Disorders of self • Unity/singleness • Autoscopy (=haeutoscopy, =phantom mirror image) » seeing oneself (haeutoscopic hallucination) » loss of feeling of familiarity » Sz (rare), parietal lobe disorders • Doppelganger (? “haeutoscopic depersonalization”) » “being outside, alongside & inside oneself” » ideational (form of depersonalization), delusional, &/or perceptual • Haeutoscopic delusion (rare) • Multiple personality » Hysterical dissociative states • Lability in awareness of personality » In Sz: believing one has become someone/something else & simultaneously believing self to be separate from it (?) – – – – – – – feel as if unreal internal &/or external change unpleasant affect always involved insight preserved often assoc. with derealization also desomatization/de-affectualization • not existing: nihilistic delusions • passivity phenomena Disorders of self • Identity • Belief of having not always been the same person » Exclusively psychotic » Sz » Characteristically a passivity experience: “been changed” • Non-psychotic feeling: as if no longer truly self » ie thoughts/feelings differ from previously accepted self » no loss of contact with reality that is in fact the same person • Loss of continuity of self over time » Sz: changed person » Depression: will not continue into future » Role in insight • Possession state » Temporary, Cultural v Pathological, Conscious level • Near death experiences » Depersonaliz’n, autoscopy, alert, trancendental exp’nces Disorders of self Psychosis Environment • Boundaries • Losing differentiation between I & not I – Sz » » » » » common feature of 1st rank Sx blurred boundaries less apparent to patient than to observers passivity hallucinosis (esp. 3rd person & hearing own thoughts out loud) delusional percept – Ecstasy states » » » » Affectively mediated: ‘as if’ Normal Personality disorders Psychotic states Movement/behaviour Self Perception s i n g l Thought /language e n e s s Time: flow / direction / uniqueness / quality Loss of distinction of ‘I’ v ‘not I’ 11