Faculty of Resource Science and Technology, UNIMAS
COURSE TITLE
MEDICAL BIOTECHNOLOGY
(Bioteknologi Perubatan)
COURSE CODE
STB3052
CREDIT
2
PREREQUISITE/S
N/A
SYNOPSIS
This is a multi- and interdisciplinary course that encompasses
subjects ranging from essential medical genetics, cancer
genetics, and gene therapy to DNA typing and fingerprinting.
Divided into 5 broad learning units, students will be taught on a
comprehensive learning package that commences with
introductory subjects to molecular and cellular medicine,
followed by the study of Molecular Parasitology and Cancer
Genetics, and concluding with discussion on application in
Biomedicine and Forensic DNA technology. The general aim of
this course is to produce students competent in the body of
knowledge that integrates molecular and cellular biology with
health and medical sciences. As biotechnological approaches are
becoming part of the prognostic and therapeutic regimes for
diseases, it is therefore necessary to have a course like
Biomedical Biotechnology that expose students to essential
information on the utilization of multi-and interdisciplinary
strategies to solve health, medical, and forensic problems.
(Ini adalah kursus multi dan antara displin yang merangkumi
subjek-subjek penting dari bidang genetik perubatan, genetik
kanser dan terapi gen sehinggalah kepada pencirian dan
pencapjarian DNA. Ia dibahagi kepada lima unit pembelajaran
umum dimana pelajar akan diajar dengan pakej pembelajaran
yang komprehensif yang mencakupi subjek pengenalan kepada
sains perubatan dari segi selular dan molekul, diikuti dengan
kajian parasitologi molekul dan genetik kanser dan akhirnya
diikuti dengan perbincangan mengenai aplikasi didalam
bioperubatan dan teknologi forensik DNA. Objektif umum kursus
ini adalah untuk menghasilkan pelajar yang kompeten didalam
bidang pengetahuan
STB3052 Medical Biotechnology
1/4
Faculty of Resource Science and Technology, UNIMAS
yang mengintegrasikan biologi sel dan molekul dengan sains
perubatan dan kesihatan. Pendekatan bioteknologi telah menjadi
sebahagian dari teknik diagnostik dan terapeutik penyakit. Oleh
yang demikian, adalah penting untuk mengadakan kursus seperti
bioteknologi bioperubatan ini yang akan mendedahkan pelajar
kepada maklumat penting didalam kepengunaan, teknik serta
stategi multi dan antara disiplin di dalam bioteknologi untuk
menyelesaikan masalah kesihatan, perubatan dan forensik. )
LEARNING
OUTCOMES
By the end of this course, students will be able to:
o Define all the technical terminology pertaining to
biomedical sciences and the various components of
biomedical sciences.
(C1)
o Explain the functions of biomolecules in the normal and
abnormal activities of human. (C2)
o Explain forensic DNA technology and its applications.
(C2)
o Analyze the relationship between biotechnological
approaches and biomedical sciences. (C4, CT)
o Apply biomedical biotechnological approaches in medical
and forensic studies. (C3, P4, ES)
STUDENT
LEARNING
HOURS
Lectures
Student-Centered Learning
Self-Study
Quizzes, Tests, & Examinations
Total
LEARNING
UNITS
1.
2.
STB3052 Medical Biotechnology
24
4
47
5
80
Hour/s
Hour/s
Hour/s
Hour/s
Hour/s
Supervised
Learning Hours
LU1: Biotechnology and Medicine.
4
Introduction to molecular and cellular medicine;
medical genetics(genetic disease, congenital
syndromes, and developmental abnormalities);
disease biomarkers; biomedical microbiology;
biomedical technology; medical genomics.
LU2: Molecular Parasitology.
Microbial genetics and disease; molecular virology
4
2/4
Faculty of Resource Science and Technology, UNIMAS
and disease; genetic basis of drug/antibiotic
resistance or tolerance; immunogenetics; molecular
vaccine and pharmacogenetics.
ASSESSMENT
REFERENCES
STB3052 Medical Biotechnology
3.
LU3: Cancer Genetics
Cancer biology (cellular growth and differentiation);
molecular organogenesis (developmental gene
markers functions/dysfunctions); molecular
oncogenesis and carcinogenesis (tumour suppressor
genes, oncogenes, DNA mismatch repair genes, cell
cycle and signal transduction factors); and cancer
genomics.
8
4.
LU4: Biomedical Biotechnological Application.
Principles of molecular biology techniques in disease
diagnostic, molecular epidemiology, cancer
detection, and surveillance of emerging infectious
diseases. Principles and approaches of gene therapy
and delivery technology.
6
5.
LU5: Forensic DNA in Biotechnology.
Human genetics and DNA fingerprinting; use of
DNA typing as a tool for solving crimes,
identification of disaster victims, determination of
ancestral lineage and parental relationship; and DNA
profiles as personnel ID.
6
Assignment 1
Assignment 2
Assignment 3
Mid semester Exam
Final exam
Total
10
10
10
30
40
100
%
%
%
%
%
%
1.
Mueller, R.F. , I. (eds.). (2001). Emery?s Elements of
Medical Genetics (Eleventh Edition). Churchill
Livingstone, UK.
2.
Macdonald, F. , C.H.J. (eds.). (1997). Molecular Biology
of Cancer. BIOS Scientific Publishers, UK.
3/4
Faculty of Resource Science and Technology, UNIMAS
3.
Templeton, N.S. , D.D. (eds.). (2000). Gene Therapy:
Therapeutic Mechanisms and Strategies. Marcel Dekker,
USA.
4.
Budowle, B., Smith, J., Moretti, T. , J. (eds.). (2000). DNA
Typing Protocol: Molecular Biology and Forensic
Analysis. Eaton Publishing, USA.
Last updated: August 22, 2011, Mon, 9:40 AM
STB3052 Medical Biotechnology
4/4