MIP 300: General Microbiology MIP 300: GENERAL MICROBIOLOGY SYLLABUS INSTRUCTOR Susan Deines, Associate Professor Office: B126 - Microbiology Building Telephone: (970) 491-2913 E-mail: susan.deines@colostate.edu Note: E-mail is the best way to contact me. I will generally respond within a 24-hour period. I am not always in the office, but my telephone calls are forwarded to my e-mail. TECHNICAL SUPPORT Need technical assistance with your RamCT course? Try the following: Visit the Help Desk web page to troubleshoot common browser and Java issues. Call 970-491-7276. Email Help Desk Support. TEXTBOOK Microbiology: An Introduction, Tortura, Funke and Case, 11th edition, Benjamin Cummings Publisher Purchase one of the following options: Hardbound Text with Access Code: Mastering Microbiology eText Access: Books a la Carte Edition (Loose Leaf): ISBN 0321767381 ISBN 0321802691 (e-text only, no bound book) ISBN 9780321796677 (no e-text option) Purchase at CSU Bookstore, directly from Pearson, or through other online outlets. The link to Pearson is http://www.pearsonhighered.com/educator/product/Microbiology-An-Introduction-Books-a-la-Carte-Edition-11E/9780321796677.page (scroll to the bottom to see all the options). MIP 300: General Microbiology COURSE WEB PAGE ADDRESS http://ramct.colostate.edu COURSE DESCRIPTION MIP300 is designed to present fundamental principles of microbiology, which will provide a foundation for other classes in the biological and physical sciences. Course topics include cell structure and function, microbial metabolism, microbial genetics, methods of controlling microbial growth, and disease transmission, treatment and prevention. Current societal issues related to microbiology will also be discussed. The hope is that students will come away from the course with an understanding of the profound impact, both positive and negative, that microbes have on everyday life. COURSE OBJECTIVES After successful completion of this course, the student will be able to ….. explain the differences between eukaryotic and prokaryotic organisms. identify characteristics used to differentiate microbes from plants and animals, as well as from one another. describe various metabolic processes used by microorganisms to generate ATP. describe how prokaryotes reproduce and viruses replicate. explain how microbes play beneficial roles in the environment. describe selected processes used to “harness” microbes to create foods, beverages, medicines, and agricultural products. explain how bacteria and viruses undergo genetic recombination. identify the pathogens that cause selected diseases and explain how these diseases are transmitted. describe physical and chemical methods for controlling microbial growth. explain how antimicrobial drugs work and why they are more toxic to the pathogen than to the host. explain how immunological principles are employed in the manufacture of vaccines and diagnostic tests. COURSE REQUIREMENTS Grades in the course are determined by the student’s performance on the exams, problems sets, online discussions, and participation questions. Responses to the problem sets, discussions, and participation questions will all be submitted electronically through RamCT. Assignment and exam due dates are listed on the Course Schedule (below). MIP 300: General Microbiology EXAM PROCTORING Exams will also be submitted through RamCT, but must be administered under the supervision of an approved proctor. Select a proctor from one of the following three options and submit a Proctor Identification Form at least two weeks prior to the first date the exam is available. Proctoring Options: 1. Use ProctorU, an online proctoring service, requiring a webcam and microphone. Schedule each exam with ProctorU at least four days before you need to take your exam. The cost for online proctoring is included in the cost of the course. 2. Take the exam at an OnlinePlus facility in Fort Collins or Denver, or at the University Testing Center (UTC) on-campus. Schedule an appointment at least three days before you need to take your exam. OnlinePlus offices do not charge for proctoring services, but the UTC does. Contact OnlinePlus at (970) 4924704 (Fort Collins) or (303) 573-6318 (Denver) or the UTC at (970) 491-6498 for more information. 3. Work with an eligible proctor outside of Colorado State University. Your proctor selection is subject to approval. Any costs incurred due to using an outside proctor are your responsibility. Please review the eligibility guidelines found on OnlinePlus Proctoring when selecting an outside proctor. Make sure you select an eligible proctor, schedule exams with your proctor, and abide by all rules for bringing only appropriate materials into the testing area. Mobile or other electronic devices are strictly prohibited. You will need to provide photo identification to your proctor prior to taking any exam. Appropriate identification includes: driver's license, CSU Student ID, passport, or other government issued photo identification. Visit OnlinePlus Proctoring for more information about your proctoring options and eligible proctors. If you have any questions or concerns about proctoring, contact OnlinePlus at onlineplus_proctoring@colostate.edu. Grading Scheme Point Distribution: Exams Problem Sets Online Discussions Participation Questions 410 130 30 45 615 Grade Composite: Grade A B C D F Percent Total Points 89.50-100 79.50-89.49 69.50-79.49 59.50-69.49 59.49 and below MIP 300: General Microbiology EXAMS (410 POINTS) Students may take each exam between midnight on Thursday and midnight Monday (local Colorado time) in the week for which an exam is scheduled. Exam dates are listed on the Course Schedule. Three 100-point written (typed) tests will be given during the course. Many of the questions are multiple-choice for which you will choose the correct answer(s) and then provide a written explanation for choosing the answer(s). Final Exam (110 points). The final will be a comprehensive exam in a multiple-choice format for which you select the correct answer. All exams are closed book, closed notes, meaning that you are not to use any outside sources while taking the exam. PROBLEM SETS (130) There will be 10 problem sets. You are responsible for this material on exams. Many of the problem sets are intended to exemplify the positive contributions of microbes. The instructor will introduce items to the class that are created using microbes and will assign a question set for each item. You will use the information provided in the lecture material, and that which you will acquire searching the Internet, to formulate answers to the questions. You will be graded on the accuracy and thoroughness of your responses. Answers that are obviously plagiarized will not be graded. ONLINE DISCUSSIONS (30 POINTS) The instructor will post three online discussion questions. For each discussion, you will respond directly to the instructor’s question and will then also respond to at least one other student’s response within the assigned week period. These are controversial topics, and I hope there will be much class discussion online. The response to each of the instructor’s questions is worth 5 points and the related response to other student(s) in the class is worth an additional 5 points. I am not looking for a specific answer here, but I want to see intelligent discussion on the topics, ideally incorporating information relevant to what has been presented in the lecture material. Only substantive responses of 100-200 words will be graded. I expect all responses to be professional – no profanity, no demeaning statements, no personal attacks, etc. Participation Questions (45 points) Students will be prompted to respond to questions related to the material throughout the course. You must respond to these questions on RamCT within a given time period. Your responses will be graded electronically and you will receive partial credit for attempting to answer the question and full credit for an answer that is correct. MIP 300: General Microbiology INSTRUCTOR POLICIES Assignments will not be accepted late. Students who miss an exam due to illness must provide documentation to that effect before make-up of the exam will be considered. Special needs statement: Students with disability are encouraged to contact Resources for Disabled Students at 491-6385 to arrange for accommodations and support services. ACADEMIC INTEGRITY POLICY This course will adhere to the CSU Academic Integrity Policies and Guiding Principles as found in the General Catalog and the Student Conduct Code. At a minimum, violations will result in a grading penalty in this course and a report to the Office of Conflict Resolution and Student Conduct Services. CSU HONOR PLEDGE Academic integrity lies at the core of our common goal: to create an intellectually honest and rigorous community. Because academic integrity, and the personal and social integrity of which academic integrity is an integral part, is so central to our mission as students, teachers, scholars, and citizens, I will ask that you affirm the CSU Honor Pledge as part of completing your work in this course. You will be asked (but not required) to affirm the following statement at the start of your exams: "I have not given, received, or used any unauthorized assistance." Further information about Academic Integrity is available at CSU’s Practicing Academic Integrity. I reserve the right to modify this syllabus and schedule. 085/20/2013 MIP 300: General Microbiology MIP 300: GENERAL MICROBIOLOGY FALL 2013 SCHEDULE UNIT 1: What Is a Microbe? WEEK DATES Week 1 Aug 26Sept 1 LECTURE TOPICS TEXT READINGS ASSIGNMENTS DUE DATES Section 1: Prokaryotic and Eukaryotic Cell Structure and Microbial Taxonomy Ch 4: 76-106 Ch 10: 273-281 Participation Question 1 Thurs, Aug 29 Section 2: The Fungi Ergot Poisoning Ch 12: 330-336 Ch 25: 445;735 Section 3: The Protists Malaria Ch 12: 343-354 Ch 23: 351-352;668-672 Problem Set 1 Sun, Sept 1 Ch 11: 300;303; 326 Ch 23: 650-652 Problem Set 2 Sun , Sept 8 Ch 13: 370-375;381-383; 385-386 Ch 21: 600-601 Ch 22: 636-637 Participation Question 2 Discussion 1 1st Response 2nd Response Thurs, Sept 5 Section 4: The Prokaryotes Anthrax Week 2 Sept 2Sept 8 Section 5: Viruses and Prions Smallpox Variant Creutzfeldt-Jakob Disease Fri, Sept 6 Sun, Sept 8 MIP 300: General Microbiology UNIT 2: Microbial Growth WEEK Week 3 Week 4 DATES Sept 9Sept 15 Sept 16Sept 22 LECTURE TOPICS TEXT READINGS Section 6: Environmental Factors Affecting Growth Botulism Staphylococcus aureus Diseases Listeriosis Ch 6: 154-160 Ch 22: 622-625 Ch 22: 591-594;717-718 Ch 22: 617-618; 619-621 Section 7: Microbial Metabolism Ch 5: 119-143 ASSIGNMENTS Participation Question 3 DUE DATES Thurs, Sept 12 Participation Question 4 Problem Set 3 Sun, Sept 15 Sun, Sept 15 Section 8: Microbes in the Environment Ch 12: 342 Ch 14: 402-406 Ch 27: 773-780 Problem Set 4 Thurs, Sept 20 Section 9: Foods and Beverages Made Using Microbes Ch 28: 805-807 EXAM #1 (Sections 1-9) Mon, Sept 23 UNIT 3: MICROBIAL GENETICS WEEK Week 5-6 Week 7-8 DATES Sept 23Oct 6 Oct 7Oct 20 LECTURE TOPICS TEXT READINGS ASSIGNMENTS Section 10: DNA Replication & Protein Synthesis Ch 8: 208-218 Participation Question 5 Thurs, Sept 26 Problem Set 5 Sun, Sept 29 Section 11: Viral Multiplication Herpesvirus infections Hepatitis A Rabies HIV/AIDS Ch 13: 386-392 Ch 21: 601-603 Ch 25: 729 Ch 22: 628-630 Ch 19: 545-554 Participation Question 6 Sun, Oct 6 Section 12: Mutation and Genetic Recombination E. coli O157:H7 gastroenteritis Influenza Ch 8: 223-228 Ch 25: 723-724 Ch 24: 699-701 Participation Question 7 Thurs, Oct 10 Problem Set 6 Sun, Oct 13 Ch 9: 245-252 Participation Question 8 Thurs, Oct 17 Problem Set 7 Thurs, Oct 17 EXAM #2 (Sect. 10-13) Mon, Oct 21 Section 13: Recombinant DNA Technology DUE DATES MIP 300: General Microbiology Unit 4: Infection and Disease WEEK Week 9-10 DATES Oct 21Nov 3 LECTURE TOPICS TEXT READINGS ASSIGNMENTS DUE DATES Section 14: The Etiology of Disease and Disease Transmission Syphilis Hepatitis B Legionnaires’ Disease Salmonellae Infections Plague Toxoplasmosis Ch 1: 8-12; Ch 14: 406-414 Participation Question 9 Participation Quest. 10 Ch 26: 758-762 Discussion Topic 2: Ch 25: 729-732 Ch 24: 694 First Response Ch 25: 719-722 Second Response Ch 23: 655-658 Ch 23: 668-669 Sun, Oct 27 Thurs, Oct 31 LECTURE TOPICS TEXT READINGS ASSIGNMENTS DUE DATES Section 15: Physical and Chemical Methods of Control Ch 7: 185-202 Participation Quest. 11 Sun, Nov 10 Ch 20: 559-577 Participation Quest. 12 Problem Set 8 EXAM #3 (Sect 14-16) Thurs, Nov 14 Thurs, Nov 14 Mon, Nov 18 TEXT READINGS ASSIGNMENTS DUE DATES Ch 16: 452-466 Ch 17: 479-500 Participation Quest. 13 Participation Quest. 14 Problem Set 9 Thurs, Nov 21 Sun, Dec 1 Sun, Dec 1 Fri, Nov 1 Sun, Nov 3 Unit 5: Controlling Microbial Growth WEEK Week 11 -12 DATES Nov 4Nov 17 Section 16: Antimicrobial Drugs Unit 6: Immunology WEEK DATES Week 13-14 Nov 18Section 17: The Immune Response Dec 1 Week 15-16 Dec 2Dec 15 LECTURE TOPICS Section 18: Practical Applications of Immunology Syphilis Tuberculosis Polio Meningococcal Disease Tetanus Participation Quest 15 Ch 18: 551-511; 518-521 Problem Set 10 Ch 22: 617-619; 621-622; Discussion 3: 626-628 1st Response Ch 24: 688-692 2nd Response FINAL EXAM Thurs, Dec 5 Sun, Dec 8 Fri, Dec 13 Sun, Dec 15 Mon, Dec 16 MIP 300: General Microbiology