Organic Chemistry Laboratory
CHM 216
Wright State University
Spring Quarter 2011
Course
Description
The purpose of this course is to introduce the student to fundamental
organic chemistry laboratory techniques and equipment used to
analyze and synthesize organic chemicals. Safety in the laboratory
will be stressed at all times. The student will also learn to have a
healthy respect for chemicals and laboratory equipment. In addition,
organizing and preparing for each experiment will require that the
student become familiar with the proper use of laboratory notebooks.
Location
064 Brehm (preceded by a recitation in different locations depending
on section number – see WINGS)
Instructor
Professor William A. Feld
Office hours: open door policy or by appointment (Rm 420 O)
(937) 775-2511, william.feld@wright.edu
Lab Director
Mr. Jonathan Grieb (O63 Brehm)
(937) 775-2790, jonathan.grieb@wright.edu
Please Note
Individual laboratories will be supervised by Mr. Jon Grieb, Organic
Chemistry Laboratory Director, and Graduate Teaching Assistants.
Most questions should be addressed initially to your GTA.
Textbooks
1) “Catalyst: The Prentice Hall Custom Laboratory Program for
Chemistry” compiled by David E. Portlock, Pearson Prentice Hall and
2) Student Lab Notebook, Hayden McNeil.
Course
Layout
Laboratory safety goggles and lab coats (available at the bookstore in
the Student Union) must be worn at all times in the laboratory. In
addition, you must have long pants (or skirt) and closed toe shoes.
Safety rules will be strictly enforced. Safety is no accident. The first
Organic Chemistry Laboratory and Recitations will meet during the
week of Monday, April 4, 2011.
Tentative Schedule
Week
Date
Scheduled Lab
Lab Book Pages
One
Apr. 4
Reaction of Iodoethane with Sodium Saccharin
97-102
Two
Apr. 11
Diels Alder Reaction Maleic Anhydride/Furan
247-248
Three
Apr. 18
Synthesis and Spectral Analysis of Aspirin
141-148
Four
Apr. 25
Nitration of Aromatic Ring (Handout)
249-250
Five
May 2
Friedel-Crafts Acylation of Anisole
149-157
Six
May 9
Haloform Oxidation: 4-Methoxyacetophenone
175-181
Seven
May 16
Borohydride Reduction of 4-Nitrobenzaldehyde
131-139
Eight
May 23
Wittig Synthesis: 1,4-Diphenyl-1,3-Butadiene
159-166
Nine
May 30
Laboratory Clean-up (mandatory)
Tues.
June 7
Comprehensive Final Exam (10:45 am-12:45 pm, 120 Med Sci)
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Recitation Each laboratory will be preceded by a 45-minute presentation of the
experiment as well as a quiz on the previous week’s lab. The presentation and quiz will
take place during the recitation component for your lab. section. Each student will be
expected to have read the pages tabulated above before lab. Attendance is mandatory!
Students will not be allowed to conduct the experiment without prior attendance at
recitation and their signatures on the sign-up sheet.
Format
Each lab should take about 2.5 hours and this should leave ample time
for clean-up and check-out with the lab instructor. The lab instructor
must sign and date your carbon copy after you have cleaned up your
work area and before you leave the lab. Reports with attached carbon
copies lacking such authentication will not be accepted. It is
imperative that you keep an organized lab notebook (see pages 463464) and write comprehensive lab reports (see pages 465-469). Lab
reports are due at the start of the following week’s recitation. Late
reports will be penalized at the rate of two points per day.
Grading
For each laboratory:
Laboratory participation
Lab report
Quiz
Clean-up and GTA checkout
Total points for each lab
Final Exam
10 points
10 points
10 points
5 points
35 points
100 points
Grading System There are eight experiments scheduled. The best seven labs will count
toward your final grade. Because you can drop one lab grade (lowest
quiz + lowest remaining lab grade), there will be no make-up labs or
lab switching. Your final grade will be based on a total possible score
of (7 x 35 points + 100 points) = 345 points. For example: A = 90%
of possible points.
Lab Reports
Lab reports are due at the start of the following week’s recitation.
Late reports will be penalized at the rate of two points per day.
With the proliferation of personal computers, it is tempting for two
students to submit virtually the same report with only minor
variations. This is plagiarism, covered by the University's Policies on
Academic Dishonesty and will be dealt with severely!
Lab Final
The comprehensive laboratory final exam will be held on Tuesday,
June 7 from 10:45 am-12:45 pm in 120 Med Sci.
Exam schedules can be found on the Registrar's website http://www.wright.edu/registrar/classinformation/examschedules/index.html
Suggestions
It is strongly suggested that students read the sections of the lab
manual for the week’s experiment before each lab. If you have
questions, ask for help during recitation or lab. Failure to
participate in lab clean-up during the week of May 30 will result
in a grade of X for this course.
Laboratory Notebook (Pre-Laboratory Material)
Before entering the laboratory, students are required to write the
requisite information needed to begin the experiment. This Pre-Lab
assignment will include a title and reference to the experiment, a
general scheme of the reaction that will be performed (if
appropriate), a table of physical constants relating to the
reactants/products to be used (chemical name, molecular weight, MP,
BP, density, solubility, etc). Finally, a general Advance Procedure for
the experiment that will be performed should also be written out with
using the approximate quantities/times given. Below that (under
Actual Procedure) the student will note actual masses/volumes of
reagents used when performing the experiment. This Pre-Laboratory
write-up will be worth 5 points each week. This is being done to
ensure that the notes which have been posted online are actually being
read prior to recitation, and that the students are prepared to begin the
experiment in a safe and timely fashion upon entering the lab.
Safety
Laboratory safety goggles and lab coats (available at the bookstore)
must be worn at all times when in the laboratory. These items may be
rented on a daily basis ($0.50/goggles, $1.00/lab coat). In addition,
the following safety rules will be strictly enforced.
1. Goggles are required at all times
2. Lab coats are required while working
3. No food or drink permitted
4. Long pants or full length skirts are required
5. Closed toed shoes are required
6. No gum
7. The use of cell phones, pagers, or headphones is prohibited in the
lab
8. No horseplay
9. No visitors
10. Gloves should never be worn outside of the laboratory
All of your attention should be directed to the experiment in progress!
Pregnancy in Academic Settings
Any student for whom this might be an issue should consult WSU's Wright Way
policy at: http://www.wright.edu/wrightway/6030.html
Organic Laboratory Cleanup Guidelines
1. Before beginning lab, check equipment station for supplies. Stock as necessary.
2. Last group to finish cleans up around balance area, IR Press and IR area.
3. Do not leave anything in the hoods and make sure they are clean before leaving.
4. If anything is left under the central hood or lab is left in an unclean state, entire
section(s) lose 5 points.
5. Do not leave glassware in or around sink. If any found, entire section(s) lose 5
points.
6. TA’ s will check drawers before signing notebook. If locker is found to be
incomplete or the glassware dirty the lab partners will lose 5 points.
7. Do not place paper towels, gloves or other trash in broken glass box. Lose 5
points.
8. Do not leave the lab or touch the door handle while wearing gloves. Lose 5 points.
9. Turn off and unplug melting point apparatus when done. Lose 5 points.
Cancellations and Closures at Wright State
Severe weather conditions may result in any of the following actions:
1) delay opening of the Dayton and/or Lake campus;
2) cancellation of non-academic activities; or
3) closing the university.
A delayed opening or a campus closure will be announced through WSU Alert,
Wright State University’s emergency notification system. Information/Alerts will be
provided via official listserv email, WSU Dayton and/or Lake campus home page,
text message (only for delay or closure of Dayton campus), campus information
lines (Dayton: 775-3333), local radio and television, and other methods. For more
information about cancellations and closures, visit
http://www.wright.edu/admin/bpra/em/closures.html.