AP BIOLOGY
(Secondary)
ESSENTIAL UNIT 5 (E05)
(Genetic Basis of Life)
(July 2013)
Unit Statement: In this unit the student will examine the cell life cycle, mitosis, meiosis,
animal development, and Mendelian genetics through the development, analysis, and
interpretation of genetic crosses, pedigrees, Chi-square problems and laboratory
experiments. Genetic disorders and chromosomal mutations will also be addressed.
Overview – Genetic Basis of Life (3 weeks)
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Cell Cycle
Mitosis and Meiosis
Reproduction
Animal Development
Mendelian Genetics
Non-Mendelian Genetics
Genetic Disorders
Essential Outcomes: (must be assessed for mastery)
1. The Student Will describe and make predictions about the events and natural
phenomena occurring during the cell cycle.
2. TSW describe representations and models that illustrate how genetic information
is copied for transmission between generations.
3. TSW construct a representation that connects the process of meiosis to the passage
of traits from parent to offspring and increased genetic diversity necessary
for evolution.
4. TSW evaluate evidence and construct an explanation, using visual representations
or narratives, as to how heritable information in the form of DNA in
chromosomes is transmitted to the next generation via mitosis, or meiosis
followed by fertilization.
5. TSW apply mathematical routines to determine Mendelian patterns of inheritance
provided by data sets.
6. TSW explain deviations from Mendel’s model of the inheritance of traits.
7. TSW describe representations of appropriate examples to explain how the
inheritance patterns of many traits cannot be accounted for by Mendelian
genetics.
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8. TSW predict the effects of changes in environmental factors on the variation of
genotypic expression and the phenotypic variations in populations.
9. TSW create a visual representation to illustrate how changes in a DNA nucleotide
sequence can result in a change in the polypeptide produced.
10. TSW pose questions about ethical, social or medical issues surrounding human
genetic disorders.
Suggested Chapters (Campbell):
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12 - The Cell Cycle
13 - Genetics
14 - Mendel and the Gene Idea
15 - The Chromosomal Basis of Inheritance
46 - Animal Reproduction
47 - Animal Development
Suggested Chapters (Starr):
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9 – How Cells Reproduce
10 – Meiosis and Sexual Reproduction
11 – Observing Patterns in Inherited Traits
12 – Chromosome and Human Inheritance
42 – Animal Reproductive Systems
43 – Animal Development
Suggested Overview of Lecture and Discussion Topics:
1.
2.
3.
4.
5.
6.
7.
8.
9.
Cell cycle and control points
Meiosis and possible errors
Animal development from fertilization of the egg
Control of developmental process: hox and homeobox genes
Mutations and changes in animal form
Mendel’s background, research and laws of inheritance
Monohybrid and dihybrid crosses
Non-Mendelian Genetics
Probability and Law of addition and law of multiplication
Suggested Activities:
1. Chi-Square M & M Lab and practice problems.
2. Cell Division: Mitosis and Meiosis: AP Investigation 7. (Smartscience Labs:
Mitosis, Effects of Environment on Mitosis, Meiosis Activity
3. Students will perform research on the connection between cell division and cancer.
They will use at least two scientific journals for their research. They will write and
present a 5-page paper.
4. On-Line Fruit Fly Crosses (Drosophila Virtual
Labs: http://sciencecourseware.org/vcise/drosophila/)
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5. Smartscience Lab Activities: Corn Genetics – Monohybrid, Corn Genetics –
Dihybrid, Sordaria Crossing Over
6. Case Study of the Death of Baby Pierre: A Genetic Mystery.
Technology Links:
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Drag and Drop Genetics: This site will give you practice with monohybrid, blood
type, sex linked and pedigree genetics problems. Useful for students struggling
with genetics or for those of you who simply want more problems.
More Genetics Problems: These problems are from a university genetics class, so
they will be more challenging.
More Drag and Drop Genetics: Another drag and drop site with more challenging
problems. This one includes:testcross, dihybrid, trihybrid, sex-linked, sexinfluenced, epistasis.
30 Genetics Problems: Great variety of 30 genetic practice problems from basic to
advanced. Be aware that there are no answers given here.
Links to the Genetic World: This site contains many valuable links. A useful
reference site for genetics projects.
BioChem Net; Molecular Genetics: A collection of web links about molecular
genetics, biotechnology, sequencing databases, problem sets, and more.
Morgan: A Genetics Tutorial: This site offers an excellent online tutorial to help
students work genetics problems.
Suggested Rubric:
The students will be evaluated for each unit according to the following rubric:
Above Mastery (A)
Mastery (B)
In Progress (P)
Multiple Choice Unit
Exam (s)
93% or better
86% - 92.9%
85.9% or lower
Free Response
Question
8 or better on the
unique rubric written
for each question
5 – 7 on the unique
rubric written for
each question
4 or below on the
unique rubric
written for each
question
Laboratory
Experiment (s)
Laboratory
experiments were
performed, data
collected and
analyzed, and written
in a concise, clear,
and accurate manner
with
graphics/diagrams
neat and complete
and appropriate
Laboratory
experiments were
performed, data
collected and
analyzed, and
written in a
concise, clear, and
accurate manner
with
graphics/diagrams
relatively neat and
Laboratory
experiments were
performed and
written in a
concise, clear, and
accurate manner
with
graphics/diagrams
lacking in
neatness and
completeness and
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QSI AP BIOLOGY E05 SEC
Copyright © 1988-2013
Study Guide,
Worksheets,
Homework, and
Notebook
terminology
according to
teacher’s instructions.
If formal lab is
requested – use Lab
Report Rubric
complete and
generally
appropriate
terminology
according to
teacher’s
instructions. If
formal lab is
requested – use Lab
Report Rubric
some appropriate
terminology
according to
teacher’s
instructions. If
formal lab is
requested – use
Lab Report
Rubric.
Study Guides,
Worksheets, and
Notebooks are
consistently up to
date, neat, and
accurate.
Study Guides,
Worksheets, and
Notebooks are
relatively up to
date, neat, and
accurate
Study Guides,
Worksheets, and
Notebooks are not
up to date, neat,
and accurate.
Information can be
easily accessed.
Information can be
somewhat easily
accessed.
It is difficult to
access
information.
If a student falls within the “P” range the following steps will be taken to complete the
outstanding unit:
1. The student will be automatically be assigned to the after-school homework
tutorial for the duration of the next unit or until mastery of the outstanding unit,
whichever comes first. In the after school homework tutorial, the following steps
should be taken:
a. First, the student must complete all unfinished work for the outstanding
unit.
b. Second, the student will use his/her time to study the necessary material
and ask for additional help if necessary.
c. Third, student will retest if necessary. If the student masters the subject
matter the second time around with an 86% or better and finished all past
work with at least a ‘B’ according to the rubric, he/she will earn a ‘B’.
2. If the student doesn’t master the outstanding unit according to the rubric during
current unit, the unit will be assessed with an H, W, or D. If a W is awarded then
no credit for that unit may be obtained in the current calendar school year, but the
student still may participate in the AP exam in May.
32
QSI AP BIOLOGY E05 SEC
Copyright © 1988-2013