Course outline
Code: MLS121
Title: Histology
Faculty of: Science, Health, Education and Engineering
Teaching Session: Semester 2
Year: 2015
Course Coordinator: Geoffrey Simon Email: gsimon@usc.edu.au
Course Moderator: Dr Ann Parkinson Email: aparkinson@usc.edu.au
1.
What is this course about?
1.1
Course description
Histology is the area of general pathology concerning cells, tissues and organs in the human body. Basic
tissue types – epithelium, connective tissue, muscle, nerves followed by the arrangement of tissues in
major organ systems, including the circulatory, lymphatic, integumentary, skeletal, nervous, respiratory,
digestive, urinary, endocrine, exocrine and reproductive systems will be covered. Development in
histological techniques used in pathology services, including light microscopy, fixation, staining, embedding,
sectioning and immunohistochemistry will also be assessed.
1.2
Course content
Microscopic cell and tissue structure
Histological features of major organ systems
• Circulatory and lymphatic systems
• Integumentary system
• Skeletal system
• Nervous system
• Respiratory system
• Digestive system
• Urinary system
• Endocrine and exocrine systems
• Reproductive system
Histological techniques – theory and practice
• Function and components of the compound light microscope
• Routine staining processes in pathology
• Fixation of tissues
• Embedding and cutting
• Frozen and cryostat sectioning of fresh tissues
• Immunohistochemistry
2.
Unit value
12 units
Version Semester 2 2015 (version 2)
Recfind File Number: F17565
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Course Outline: MLS121 Histology
3.
How does this course contribute to my learning?
On successful completion of this course you
should be able to:
Identify, describe and classify the microscopic
structure of human cells and the basic tissues
types through the compound light microscope
and virtual slides
Identify, describe and classify the morphological
features of major organ systems in the human
body
Show competency in histological techniques, for
routine preparation of cells and tissue for
compound light microscopy
4.
You will be assessed on
the learning outcome in
task/s:
Task 1, 2 and 3
Completing these tasks
successfully will contribute
to you becoming:
Knowledgeable.
Task 1, 2 and 3
Knowledgeable.
Task 2 and 3
Empowered.
Am I eligible to enrol in this course?
Refer to the Undergraduate Coursework Programs and Awards - Academic Policy for definitions of “prerequisites, co-requisites and anti-requisites”
4.1
Enrolment restrictions
Nil
4.2
Pre-requisites
LFS100
4.3
Co-requisites
LFS112 Human Physiology
4.4
Anti-requisites
Nil
4.5
Specific assumed prior knowledge and skills (optional)
N/A
5.
How am I going to be assessed?
5.1
Grading scale
Standard – High Distinction (HD), Distinction (DN), Credit (CR), Pass (PS), Fail (FL)
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Course Outline: MLS121 Histology
5.2
Task
No.
1
2
3
Assessment tasks
MLS121
Assessment
Tasks
Review Quizzes
Individual
or Group
Weighting
%
Individual
Practical
Histology Exam 1
Practical
Histology Exam 2
Individual
25% (5%
per quiz)
35%
Individual
40%
What is the
duration /
length?
20 mins per
quiz
2 hours + 10
mins perusal
2 hours + 10
mins perusal
When should I
submit?
Where should I
submit it?
Week 3, 5, 7, 9, 11
week 10
In class and
online
Practical class
Week 13
Practical Class
100%
Assessment Task 1: Review Quizzes
Goal:
To identify, describe and understand the compound light microscope, microscopic structure of
human cells, the 4 basic tissues types and organ systems of the human body.
Product:
Review Quizzes
Format:
Multiple choice/short answer questions
Criteria
You will be assessed on your ability to:
- recall factual information in the MLS121 Histology teaching materials
- solve problems based on theoretical material and information covered in lectures, laboratories
and tutorials
Generic skill assessed
Skill assessment level
Problem solving
Introductory
Assessment Task 2: Practical Histology Exam 1
Goal:
To develop satisfactory laboratory skills and competencies in Histology that would meet the
requirements of the QLD pathology industry for training medical science technicians. Students
must complete the training for this assessment in the preceding labs before attending the exam.
This is a health and safety requirement.
Product: Application of histology techniques to prepare tissue samples for morphological identification.
Format:
You will bring in records of the preceding lab training sessions to gain entrance into this exam.
Your tutor and lecturer will sign your lab book for each lab and associated lab work completed.
This is your evidence that you have been appropriately trained and can demonstrate appropriate
health and safety measures to undertake this exam.
Practical histology techniques at industry standard
Criteria
You will be assessed on safety in the laboratory and your ability to embed and section a paraffin
tissue sample, undertake staining processes used in pathology testing, identify and describe the
techniques for tissue fixation, processing and cryostat sectioning
Generic skill assessed
Skill assessment level
Applying technologies
Introductory
Problem solving
Introductory
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Course Outline: MLS121 Histology
Assessment Task 3: Practical Histology Exam 2
Goal:
To develop satisfactory laboratory skills and competencies in Histology that would meet the
requirements of the QLD pathology industry for training medical science technicians. Students
must complete the training for this assessment in the preceding labs before attending the exam.
This is a health and safety requirement.
Product:
Format:
Morphological identification of histology tissue sections.
You will bring in records of the preceding lab training sessions to gain entrance into this exam.
Your tutor and lecturer will sign your lab book for each lab and associated lab work completed.
This is your evidence that you have been appropriately trained and can demonstrate appropriate
health and safety measures to undertake this exam.
Practical histology techniques and morphological identification at industry standard
Criteria
You will be assessed on your ability to recognise, describe and understand the techniques used
to identify the morphological features of organ systems in the body using glass slides with the
light microscope and virtual slides on the computers.
Generic skill assessed
Skill assessment level
Problem solving
Introductory
Applying technologies
Introductory
5.3
Additional assessment requirements
Eligibility for Supplementary Assessment
Your eligibility for supplementary assessment in a course is dependent of the following conditions applying:
a) The final mark is in the percentage range 47% to 49.4%
b) The course is graded using the Standard Grading scale
c) You have not failed an assessment task in the course due to academic misconduct
Blackboard
As a student enrolled in this course you will have access to course information on the Blackboard site. You
are strongly recommended to log onto the course site on a regular basis. All course announcements,
course changes, posting of course materials and grades (via My Interim Results) will be accessed through
Blackboard. It is your responsibility to ensure you have adequate internet access (either off campus or oncampus) in order to access Blackboard regularly and to complete required assessment tasks.
Safe Assign
In order to minimise incidents of plagiarism and collusion, this course may require that some of its
assessment tasks are submitted electronically via Safe Assign. This software allows for text comparisons to
be made between the students submitted assessment item and all other work that Safe Assign has access
to. If required, details of how to submit via Safe Assign will be provided on the Blackboard site of the
course.
5.4
Submission penalties
Late submission of assessment tasks will be penalised.
To request an extension you must contact your course coordinator to negotiate an outcome.
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Course Outline: MLS121 Histology
6. How is the course offered?
6.1
Directed study hours
2-hours lecture each week
3-hours of compulsory laboratory each fortnight
1-hour tutorial each week
One day intensive practical (held in week 10)
6.2
Teaching semester/session(s) offered
Semester 2
6.3
Course activities
Teaching
Week /
Module
What key concepts/content will I
learn?
1
Introduction to Histology
• Cell structure in detail
• Overview of the basic tissue types
• Organ systems
• Overview of histological techniques
• Light and electron microscopy
2
Epithelial Tissues
• Squamous, cuboidal, columnar
• Simple and stratified
• Distinguishing cellular structures
Muscle Tissues
• Skeletal muscle fibre types
• Cardiac muscle fibres
• Smooth muscle cells Connective Tissues
Practical Histology: Fixation of tissues
3
4
5
6
Connective tissue proper
• Blood
• Cartilage and bone
Practical Histology: Routine stains & special
stains
Nervous System
• CNS & PNS
•The neuron and structural classification
• Neuroglia
Practical Histology: Dehydration, clearing,
embedding and sectioning
Respiratory System
• Upper respiratory passage and nasal cavity
• Respiratory epithelium
• Trachea
• The lungs, and pleural cavities and
membranes
What activities will I engage in to learn the
concepts/content?
Directed Study Activities
Independent Study
Activities
Practical 1:
• Laboratory induction
• Practical light microscopy
• Overview of the basic tissue types
Week 1 Tutorial
An introduction to virtual histology
images
Week 2 Tutorial:
• Epithelium
Recommended Text Chapter
1 (overview of Chapters 4, 5,
9 & 10)
Practical 2:
• Routine staining for cells and tissues
• Histology of epithelial and muscle
tissue
Week 3 Tutorial
Muscle
Assessment Task 1a: Review Quiz &
Feedback
Week 4 Tutorial:
• connective tissue
Chapter 10
Practical 3:
• Embedding and sectioning of tissue
• Histology of the nervous tissue
Week 5 Tutorial: Nervous system
Assessment Task 1b: Review Quiz &
Feedback
Chapter 9
Week 6 Tutorial:
• Virtual slides: Respiratory
Chapter 17
Chapter 4
Chapters 5 and 6 (overview
of Chapters 7, 8 & 12)
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Course Outline: MLS121 Histology
7
Circulatory and lymphatic Systems
• Sections of the heart
• Blood vessels
• Components of the lymphatic system
8
Urinary System
• Sections of the kidneys (nephron structure)
• Ureters, urinary bladder and urethra
9
10
11
12
Practical Histology: Cryostat sections
Digestive System and Accessory Organs
• The mucosa and submucosa
• Muscularis externa
• Serosa
• Pancreas
• Gallbladder
Integumentary System
• Epidermis, dermis, hypodermis
• Accessory structures (hair, nails, exocrine
glands)
Practical Histology:
• Practical Histology : Immunohistochemistry
Skin Research
Reproductive System 1
• Male – histology of the testes and
accessory glands
• Female – histology of the ovaries, cervix,
uterine tubes, uterus, vagina and mammary
glands
Reproductive System 2 & Skeletal System
• Bone cells and the matrix
• Compact bone structure
• Periosteum and endosteum
Practical 4:
• Embedding and sectioning of tissue
• Histology of respiratory & ,
Circulatory systems
Week 7 Tutorial: Circulatory &
Lymphatics Systems
Assessment Task 1c: Review Quiz &
Feedback
Week 8 Tutorial:
• Virtual slides: urinary
Chapters 11 & 14
Practical 5:
• Histology of Urinary and GIT
systems
Week 9 Tutorial
• Virtual slides: GIT
Assessment Task 1d: Review Quiz &
Feedback
Mid-Semester Break
Week 10 Tutorial:
• Virtual slides: Skin
Chapter 15 & 16
Chapter 19
Chapters 18
Assessment Task 2: Practical
Histology Examination 1
Tuesday 6th Oct 8-12pm
Practical 6:
• Histology of integumentary and
reproductive systems
• Practice morphology exam
Week 11 Tutorial:
• Virtual slides: Reproductive System
Assessment Task 1e: Review Quiz &
Feedback
Week 12 Tutorial:
• Virtual slides: skeletal systems &
review of endocrine/exocrine tissues
13
Endocrine and Exocrine Systems
Assessment Task 3: Practical
• Histology of selected endocrine and
histology examination 2
exocrine glands
NO Tutorial Week 13
Please note that the course activities may be subject to variation.
Chapters 21 & 22
Chapters 7 & 8
Chapter 20 (overview of
Chapter 16)
7. What resources do I need to undertake this course?
7.1
Prescribed text(s)
Please note that you need to have regular access to the resource(s) listed below:
Author
A.L. Mescher.
Year
2013
Title
Junqueira’s Basic Histology Text and Atlas
13th Ed
Publisher
McGraw Hill, New York
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Course Outline: MLS121 Histology
7.2
Required and recommended readings
Lists of required and recommended readings may be found for this course on its Blackboard site. These
materials/readings will assist you in preparing for tutorials and assignments, and will provide further
information regarding particular aspects of your course.
1. Netter’s Essential Histology (2013, 2nd Edn.). W. Ovalle, P Nahirney. Saunders Elsevier, USA (ISBN: 1929007-86-8)
7.3
Specific requirements
MLS121 is structured to provide you with knowledge and practical skills necessary to meet industry
established proficiency standards for your subsequent MLS131 Pathology Placement 1. It is therefore an
expectation of both the University and our industry partners that you will participate in all of the
directed study activities (lectures, laboratories, tutorials) and demonstrate satisfactory proficiency in the
practical assessment in order to evidence your preparedness for the placement. You are required to
complete the WHS laboratory induction and successfully complete the quiz before the first practical
session, wear appropriate personal protective equipment (PPE) during the practical component, including
covered, non-slip shoes, laboratory coat/gown and safety glasses, long hair should be tied back.
7.4
Risk management
There is minimal health and safety risk in the laboratory components of this course. However, once you are
on placement or working following graduation, you may handle infectious and other samples and be
exposed to other risks. Development and demonstration of competencies through participation in
laboratory practicals are critical to prepare you for working in industry. It is your responsibility to familiarise
yourself with the Health and Safety policies and procedures. The practical manual provides information
regarding safety in the laboratory, information for handling or working with equipment and consumables in
a safe manner. The laboratories are used for practicals involving human tissues and fluids, and there is to
be no eating or drinking in the laboratories. It is your responsibility to be safety conscious for yourself and
those around you. Be aware of the safety precautions when handling equipment, chemical solutions, glass
and tissues/fluid.
8.
How can I obtain help with my studies?
In the first instance you should contact your tutor, then the Course Coordinator. Student Life and Learning
provides additional assistance to all students through Peer Advisors and Academic Skills Advisors. You can
drop in or book an appointment. To book: Tel: +61 7 5430 1226 or Email:
studentlifeandlearning@usc.edu.au
9.
Links to relevant University policies and procedures
For more information on Academic Learning & Teaching categories including:
•
Assessment: Courses and Coursework Programs
•
Review of Assessment and Final Grades
•
Supplementary Assessment
•
Administration of Central Examinations
•
Deferred Examinations
•
Student Academic Misconduct
•
Students with a Disability
http://www.usc.edu.au/university/governance-and-executive/policies-and-procedures#academic-learningand-teaching
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Course Outline: MLS121 Histology
10. Faculty specific information
General enquiries and student support
Faculty Student Support Office
Tel: +61 7 5430 2869
Fax: +61 7 5456 5010
Email: SHEinfo@usc.edu.au