BIOS 100 Fall 2015 Biology of Cells & Organisms MWF 11 AM Lecture Center A1 CRN #13580 Instructors: Robert Paul Malchow, Ph.D. paulmalc@uic.edu 413-­3614 4083 SEL Mike Muller mmuller@uic.edu 996-­3476 Office Hours: Dr. Malchow Wednesday 8:30-­10 am outside my lab, 4083 SEL, and Wednesday 1-­2 pm in the Commuter Center, 2nd floor, SCE. No appointment needed! (if these times don’t work, contact via email to set up a meeting) Mike Muller: Wednesday 10-­12 am and by appointment Course Description: Bios 100 and its companion course Bios 101 serve as introductions to critical ideas and issues in contemporary biology. They are designed to provide the student with the intellectual foundation to handle these topics at more advanced and detailed levels in upper division courses. Lectures in Bios 100 survey fundamental concepts related to the chemical basis of life, biological chemistry, the structure and function of cells and organisms, DNA and RNA, molecular genetics, cellular replication, organismal development and function, energy transformation, respiration and photosynthesis. Laboratory assignments are designed to provide an introductory hands-­on experience to deepen students’ understanding about the nature of biological inquiry. Topics include basic microscopy and quantitative analysis, examination of cell structure, characteristics of enzyme function, cellular respiration, photosynthesis, mitosis & meiosis, and DNA, and structural and functional characteristics of plants and animals. Animals will be used in the laboratory. The discussion section is designed to connect the lecture and lab topics to current issues and research in the Biological Sciences that are likely to affect students’ lives. Among the topics expected to be discussed are cloning, personal genomics, GM organisms, antibiotic resistance, the Green Revolution, and the nature of scientific knowledge. It will also allow time for review as well as group retakes of exams. There is a significant amount of biochemistry and chemistry-­related material in this course. Students are strongly advised to take a chemistry course prior to taking Bios 100. This course is designed for those planning to pursue Biology-­related topics in depth in the future. Bios 100 is not a course recommended for those who have little or no background in the sciences. Textbooks & Other Materials: Required: -­ Text: UIC Custom edition of BIOLOGICAL SCIENCE, 5th Ed, by Scott Freeman;; Pearson Press, 2013 and access to the website associated with the 5th edition of “Mastering Biology”. (NOTE: you DO NOT NEED to purchase the virtual labs) -­ BIO 100 lab manual by Michael Muller (lab manual, sold only at UIC bookstore) -­ iClicker, available at the UIC Bookstore. Register your iClicker through the course Blackboard web site (more below). We have worked with Pearson Press to providing all the information needed for the course while Saving Students Money by developing a specific version of the materials needed for Bios 100. The UIC book store carries this special version, which includes all the chapters we use in Bios 100 printed out, as well as a code for web access to Mastering Biology, which we will use extensively, through our Blackboard course site. The package also includes electronic access to the complete Freeman text available for 2 years from the date of purchase. We believe it is a price-­effective package. Alternatively, you can purchase a hard copy of the entire text by Scott Freeman (4th or 5th edition is fine), but then you MUST purchase access to Mastering Biology through our blackboard web link. Access to the Mastering Biology will be through a link on blackboard. If you want to purchase this item separately, you must purchase access to Mastering through our Blackboard link – you cannot purchase the correct version at “masteringbiology.com” or any other web site! Optional: -­ A Photographic Atlas for the Biology Laboratory, by Van de Graaff & Crawley, Morton Publishing. iClicker registration: iClicker is a response system that allows you to respond to questions posed in class. Students receive participation points for doing so. iClicker remotes need to be registered within the first 3 (three) weeks of class. To register your iClicker, log in to Blackboard, select the Bios 100 course, go to Tools, and click on the link that says “Register your iClicker”. Note: no other way of registering the iclicker will work;; you MUST register it through the Blackboard website. The remote ID is the series of numbers and letters on the back of the iClicker. If you cannot read the number on the clicker, the UIC Book store has a means to determine the number. iClickers will be used every day in class, and you are responsible for bringing your remote daily. No clicker, no points – if you forget your clicker, you lose that day’s point. Disabilities: Students with disabilities who require accommodations for access or participation in this course must be registered with the Disability Resource Center;; contact: 312-­413-­2183(voice) or 312-­413-­0123(TTY). The Disability Resource Center is located at the Student Services Building (SSB), 1200 W. Harrison St., Room 1190 SSB (MC 321) Chicago, IL 60607 Academic Dishonesty Policy: Any student caught copying others' work on an assignment or exam or cheating in any other way will receive a zero for that assignment or exam and will be referred to the Student Judicial Affairs Committee, the Department Chair and/or Dean. Be sure to give proper attribution when using others' work in laboratory assignments. Lecture Capture: We will be using a video/audio lecture capture system to capture instructor presentations and make them available to students. These materials must NOT be put up on any other public venue by students (putting them on your personal computer or IPOD is fine). Laptops and Cell Phones: We ask that students NOT use laptops, tablets or phones for any other purpose than viewing course materials and taking notes. Please, no texting or cell phone use in the lecture, labs and discussion sections. Courtesy to other students: The lecture hall, A1, is very large and prone to noise, making it very difficult for students in the back to hear the lecture. PLEASE refrain from talking in class. If there is a need for a student to leave the class early, they should do so quietly. NOTE: We reserve the right to make changes in this syllabus. Any changes will be announced in lecture or posted on Blackboard. Coming to class will be important for keeping current on if and how the syllabus changes. Grading: The point levels below are guarantees -­ for example, if you earn 840 points, you are guaranteed a B. We will never raise the grading scale. However, at the end of the semester, we may lower it. Please don't pester us too much about this -­ we won't know if the scale will move or not until after the final exam is graded at the end of the semester -­ it usually doesn’t change at all! Point values: Maximal points that can be obtained are: 600 points on exams, 100 points for lab, 45 points for review questions & pre-­lab quizzes asked during the discussion section, 45 points for discussion of related articles in the discussion section, 10 points for leading a discussion section, 70 points for Group Projects and evaluation of those projects, 100 points for completing the assigned exercises in Mastering Biology and other associated assignments, and 30 points for iClicker use. There are thus a total of 1000 points. Grading scale: 900-­1000 A 800-­899 B 700-­799 C 600-­699 D 0-­599 F Grades for exams, labs, discussions and clicker points will be posted on the UIC Blackboard course site. Mastering Biology will have its own grade book. Make sure to check the accuracy of your grades in the grade book on a regular basis. Clicker points must be checked on the Blackboard grade book by the end of the third week of the semester to make sure they are being input correctly. Students failing to check their clicker grades have the potential to lose clicker points. Exams: Each hourly examination is comprised of either 40 or 50 multiple-­choice questions and is worth a total of 150 points. There are a total of 5 exams – 4 during the course, and the final exam. If an exam is not taken, the score for that exam will be counted as a zero. In calculating grades, the exam having the lowest score will be dropped. This policy is in place to allow students who must miss one exam due to circumstances beyond their control (for example, illness or an accident) to do so without penalty -­ the score for that exam will be dropped. If a student has taken the first 4 exams, the final examination is thus optional. If you choose to take the final exam and have taken the other four exams, we will drop the lowest exam score. Note that there is no penalty for taking the final examination even if you have taken all four other exams -­ if the final is your lowest score, we will drop the final examination score. If you miss one of the four hourly examinations, you must take the final examination. To be clear, there will be NO MAKE-­UP EXAMS – we simply drop one of the exam scores. The final exam is cumulative and will contain about half old and half new questions. Students will take each exam twice. Exams will first be taken as usual, in the classroom by the student working along without the aid of any ancillary material. This will count for 80% of the 150 points for the student’s exam grade. Students will then take the same exam (with the same questions) with a small group of other students, and may discuss potential answers together. Students may also consult any other ancillary materials that they chose. The exam “retake” will be worth a maximum of 20% of the 150 points possible for each exam. The first three exam retakes will take place during the Discussion period of the week of the exam. The retake for the fourth exam will be a “take-­home” retake, due at the beginning of the final exam during exam week. There will be a retake for the final exam as well on the day the final exam is given;; the “solo” exam will take the first hour of the exam period, then followed directly after by a one hour retake of the final exam. There will be a total of 600 possible points available for exams. Labs: There are 10 laboratory exercises, each worth 10 points;; the lowest laboratory grade will be dropped. In addition, in week 13, there will be a fetal pig mini-­practical worth an additional 10 points;; the practical CANNOT be dropped. All told, there are thus 100 possible lab associated points. No make-­ups for labs will be allowed – this is the reason we allow one of the labs to be dropped. All lab data (descriptions, drawings, etc.) are to be initialed by the lab instructor prior to leaving the laboratory. The lab assignments are to be submitted to the lab instructor at the beginning of discussion of the following week. Failure to obtain the initials of the instructor will result in receiving zero points for the lab. Some of the laboratories use stains and chemicals which can damage clothing, so please dress accordingly to laboratory. Neither UIC nor the Biology Department will assume any responsibility for damaged clothing. Also, there will be a fetal pig dissection that encompasses two of the lab sessions. If you have religious or ethical objections to this, please contact Michael Muller as soon as possible. An alternate exercise may be assigned. Discussions & Prelabs: The Discussion hour portion that precedes each lab is required and will include two components -­ a lecture review and prelab quiz, followed by a discussion on several required readings (note: during weeks when there are group retakes of exams, these will be given during discussion and there will be no lecture review, prelab quizzes or articles to read). The lecture review and prelab quiz will consist of 10 questions relating to the upcoming lab as well as material covered in lecture. There will be 10 lecture review / prelab quizzes each worth 5 points and the lowest score will be dropped, for a total of 45 points. Additionally, there will be 10 discussion sessions with required articles. Your TA will grade you based on participation -­ each session will be worth 5 points and the scores from the lowest one will be dropped;; thus a total of 45 points are possible for the discussions. Finally, each student (acting in a group of 4) will be required to lead one discussion;; students will be given 10 additional points for leading one discussion. The discussion topics can be found in the “Discussion Topics” folder in Blackboard. Note that there will be no Discussion points for the “retake” of exams – rather, students earn points on the exam score by doing the exam retake. Group Presentations: There is a group project that you and your lab group will present to the class, worth a total of 70 points. The presentation will focus on research being done in a laboratory here at UIC or somewhere in the Chicago area. Students will be expected to describe the overall nature of the research projects being done in a given lab, and to go over the results of one paper recently published from that lab. Point structure for group presentation: 10 points -­ paragraph-­length summary of the research paper in week 3. 10 points -­ initial version of a power point file focusing on the research week 6 10 points -­ for visit to lab – lab guide signs sheet indicating attendance by week 8 40 points – power point presentation about paper & lab weeks 9/10 Attendance to the other groups’ presentations is mandatory as you will be assessing their presentations. If you fail to attend and perform peer evaluations, you will lose 10 points from your project score. Mastering Biology exercises: There will be a number of Mastering Biology exercises to perform, as well as several assignments whose point value will be added in with the Mastering Biology scores. The Mastering Biology assignments will be done on the Mastering Biology web site. A score for each Mastering Biology assignment will be given (you get two chances to answer the question correctly before it is marked as incorrect), which will be stored on the Mastering Biology website and not on blackboard and will likely show a much larger total score. Your Mastering Biology total for the semester will be scaled down to a total score out of 100 points at the end of the semester. Mastering Biology assignments will have specific due dates throughout the semester, listed on Blackboard and on the Mastering Biology web site;; assignments not completed by the due dates can still be submitted until the final day of class (that is, 11:59 pm on the Friday before final exam week), but students will only receive ½ credit for their responses. A number of these exercises will be “reading quizzes”, designed to ensure that students read the appropriate material prior to attending the class lectures on these topics. Thus, you will be expected to read some material from the textbook and answer some basic questions about the material before it is covered in depth in class. Mastering Biology assignments will be structured so that students have two chances to get an answer correct during the session. iClickers: There will be points associated with using iClickers during the lectures. A total of 30 points for their use during lecture are possible. We anticipate using the clickers almost every class. Students will need to answer 75% of the clicker questions asked in class in order to receive clicker credit for the session (the actual number of clicker questions asked per session will vary from one session to another). There may be more or less than 30 clicker sessions, but we will normalize the number of points to 30 when calculating grades. The score from two clicker sessions will be dropped when calculating the grades. If you are in class but have forgotten to bring your clicker, you miss picking up that day’s clicker point – remember to bring your clicker with you. Check your clicker points on a regular basis – they will be posted on the Blackboard grade book. If there seem to be problems, come to office hours to straighten them out. Clicker points must be checked on the Blackboard grade-­book by the end of the third week of the semester to make sure they are being input correctly. Students failing to check their clicker grades have the potential to lose clicker points. You may only use one clicker in class (yours) – please do not bring clickers for friends who are not in the class or discussion. A student seen with multiple clickers will be asked to leave the lecture/ discussion section and may be referred to the Student Judicial Affairs Committee. Remember that you MUST register your iclicker through our Blackboard course site to have points automatically uploaded to the grade book. Registering over the web through the iclicker web site will NOT work. Counting up the points: Do NOT rely on Blackboard to give you an accurate total for the sum of all your points. As noted above, we drop one exam, one lab, one discussion, one prelab, and two clicker sessions. Blackboard does not consider these drops when it calculates the scores. Thus, the column of “Total Points” in Blackboard will never give a correct account of what your final points for the course will be! Late Registration Policy: Student who register after the first day of class will be required to view the lectures they have missed using lecture capture and to prepare a one page written summary for each of the lectures missed. The summary pages Must be handed to your teaching assistant no later than Friday’s class of the third week. Once handed in, students will receive one clicker point for each summary sheet turned in. The first exam is on Monday of the 4th week of class. The purpose of the late registration policy is to ensure that students are familiar with all the material that will be covered on the first exam and increase the likelihood that students will perform well on this exam. Additional Notes: • In discussion and laboratory, students frequently work in groups. However, all assignments are individual efforts, not group efforts. We encourage students to discuss answers before hand, but all work submitted must be the student’s own. If lab exercises are copied, all parties involved will receive zero credit. • All discussion and laboratory assignments must be initialed by your TA before you leave. Assignments submitted without TA initials will receive zero credit. • No lab make-­ups are allowed. This is why students get to drop a prelab, discussion, and a lab grade. • We are not responsible for lost exam scantrons -­ if a student’s scantron is lost, the student will not receive a grade for that exam and must take the final. • Blackboard is meant to be a place where students can find out their scores on labs and exams. However, it does not drop the lowest exam or labs. Keep this in mind when determining your grades. • Students are ultimately responsible for keeping track of their grades. Students are encouraged to keep track of clicker points and point out any problems in a timely fashion. Lab schedule Week Topic 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Discussion will meet;; HOWEVER, – no lab this week Techniques in Microscopy Quantitative Techniques and Statistics Cell Structure Reflects Function *** Determination of Properties of the Enzyme Turnip Peroxidase Cellular Respiration Photosynthesis *** Paternity Testing in Whooping Cranes Group Presentations & Evaluations Group Presentations & Evaluations Mitosis and Meiosis *** Comparative Anatomy of Animal System *** Animal Anatomy Mini-­Practical Thanksgiving – NO LAB or DISCUSSION Plant Reproduction *** Chapter in Muller 2 1 3 5 Blackboard 11 9 8 10 10 13 *** Laboratories in which the book A Photographic Atlas for the Biology Laboratory, by Van de Graaff & Crawley will be useful. Discussion schedule (topics of articles subject to change!!!) Week Discussion Activities 1 Meet;; description of expectations;; how to find a scientific paper;; no quiz 2 Advice to an undergrad, Bloom’s and the nature of learning;; review quiz 3 Group project discussion & group formation;; review quiz 4 Retake of exam 1 during discussion;; no quiz 5 Antibiotic resistance articles;; review quiz 6 Toxicity of sugar articles;; review quiz 7 Plants are important articles;; review quiz 8 Retake of exam 2 during discussion;; no quiz 9 Personal Genome articles & review quiz 10 Mitochondrial replacement articles;; review quiz 11 Stem cell articles;; review quiz 12 Retake of exam 3 during discussion;; no quiz 13 GMO articles;; review quiz 14 No Discussion;; Thanksgiving 15 Testing articles & evaluation of course and students;; review quiz Week Date 1 Aug 24 26 28 31 Sept 2 4 7 9 11 14 16 18 21 23 25 28 30 Oct 2 5 7 9 12 14 16 19 21 23 26 28 30 Nov 2 4 6 9 11 13 16 18 20 23 25 27 30 Dec 2 Cell theory, cell structure Cell structure, cell function Cells & proteins Proteins-­ structure and examples Proteins, chemical bonds, & water Chemical evolution, Carbohydrates LABOR DAY – NO CLASS Carbohydrates & lipids Lipids Exam 1 – covers weeks 1-­3 Cellular Respiration Cellular Respiration Cellular Respiration Photosynthesis Photosynthesis Photosynthesis DNA, RNA, protein: central dogma How genes work Transcription Translation Control of Gene expression in prokaryotes I Exam 2 – covers weeks 4-­7 Control of Gene expression in prokaryotes II Gene expression in eukaryotes Cell cycle, Mitosis DNA synthesis Meiosis Development I Stem Cells, Cloning, IVF Development II Cell-­cell interactions Intro to physiological principles Power of water in physiological systems Exam 3 – covers weeks 8-­11 Intro to osmotic regulation I Intro to osmotic regulation II Gas exchange & circulation I Gas exchange & circulation II Intro to Nerve & Muscle function Plant Anatomy & Physiology I Plant Anatomy & Physiology II THANKSGIVING – NO CLASS Plant Diversity & Reproduction I Plant Diversity & Reproduction II 4 10 Exam 4 Covers weeks 12-­15 Final Exam exact time To Be Determined 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Topic Chapter 5th ed. Freeman 7 7 7, 3 3, 8 3, 2 3, 2 Lecturer Malchow Malchow Malchow 5, 6 6 9 9 9 10 10 10 4 16 17 17 18 Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow 18 19 12 15 13 22 22 23 11 42 2, 43 43 43 45 45 46, 48 37 37 Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Malchow Muller Muller 31, 41 31, 41 Muller Muller