TRACKS _____________________________________________________________________ INFECTIOUS DISEASE EPIDEMIOLOGY Dr. Shruti Mehta, Director The development of antibiotics, improved access to safe food, clean water, sewage disposal and vaccines has led to dramatic progress in controlling infectious diseases. Despite these remarkable achievements, infectious diseases remain the leading causes of death in many parts of the world. Emerging diseases, such as antibiotic-resistant bacteria, SARS coronavirus, and avian and swine influenza viruses have been identified and some have become established in both the developed and developing world. The aim of the infectious disease track is to build upon the core epidemiology curriculum to provide students with the requisite knowledge of the epidemiology, analytical and laboratory methodology, immunology and pathogen biology necessary to understand the dynamic interactions of infectious agents and their hosts, vectors and environment. Capitalizing on the wide range of infectious disease interests at the school, students in this track take a range of courses offered in the Department of Epidemiology and other departments to obtain a broad and thorough understanding of infectious disease epidemiology. A strength of Infectious Disease Epidemiology is the substantial involvement of faculty with preeminent national and international studies of infectious diseases. The Department is particularly strong in the area of HIV/AIDS, where faculty established vanguard studies, including the Multicenter AIDS Cohort Study (MACS) and AIDS Linked to the Intravenous Experience (ALIVE) that have made fundamental contributions to the epidemiology of HIV/AIDS in the United States. Other areas of focus include other chronic infections such as hepatitis infections and tuberculosis as well as acute infections including dengue, cholera, malaria, influenza. Research studies within the program range from the molecular to behavioral, from population-based surveys to long-term observational studies to large scale cluster-randomized trials to test behavioral and pharmacologic interventions. Through seminars and discussions with faculty, students become familiar with ongoing projects within the Infectious Disease Epidemiology concentration. These projects afford unique opportunities to gain research experience not obtained through coursework, as well as valuable settings for masters and doctoral thesis projects. In the Infectious Disease Epidemiology track, masters and doctoral students are required to complete a minimum number of credit hours in required and elective courses in four broad categories as listed below. These four categories are 1) required core courses in infectious disease epidemiology; 2) biology and pathogenesis of infectious diseases; 3) advanced analytical and statistical methods (for PhD and ScD students); and 4) electives in infectious disease epidemiology. Students should meet with their academic advisors to plan an enriching program that will meet their individual academic goals. Required and elective courses may be revised periodically. INFECTIOUS DISEASE EPIDEMIOLOGY ACADEMIC GUIDE 2013-2014 TRACKS _____________________________________________________________________ Required Core Courses in Infectious Disease Epidemiology All students are required to take the courses listed below: Course 340.627 340.609 340.653 Title (credits)(term) Epidemiology of Infectious Diseases (4)* (2nd) Concepts and Methods in Infectious Disease Epidemiology (3) (3rd) Epidemiologic Inference in Outbreak Investigation (3) (4th) 260.611 Principles of Immunology I (4) (1st)(suggested 2nd year) AND Principles of Immunology II (4) (2nd) OR Immunology, Infection and Disease (3) (2nd)(suggested 2nd year) 260.612 260.631 340.660 340.717 183.631 Practical Skills in Conducting Research in Clinical Epidemiology & Investigation (3) (1st) (suggested 2nd year) OR Health Survey Research Methods (4) (2nd) (suggested 2nd year) Fundamentals of Human Physiology (for non-MD doctoral students) (4) (2nd) (suggested 2nd year) Biology and Pathogenesis of Infectious Diseases All students are required to take at least one of the courses listed below: Course 340.654 260.622 260.623 260.627 260.636 260.650 Title (credits)(term) Epidemiology and Natural History of Human Viral Infections (6) (3rd in class, 1st online) Principles of Bacterial Infection (3) (4th) Fundamental Virology (4) (1st, suggested 2nd year) Pathogenesis of Bacterial Infection (4) (2nd) Evolution of Infectious Disease (3) (1st) Vector Biology and Vector Borne Diseases (3) (3rd) Advanced Analytical and Statistical Methods for PhD and ScD Students in Infectious Disease Epidemiology PhD and ScD students are required to take at least one of the courses listed below: Course Title (credits)(term) 340.677 Infectious Disease Dynamics: Theoretical and Computational Approaches (3) (4th) 340.728 Advanced Methods in the Design and Analysis of Cohort Studies (4) (1st) 140.641 Survival Analysis (3) (1st) 140.655 Analysis of Longitudinal Data (4) (3rd) 140.656 Multilevel Statistical Models in Public Health (4) (4th) 140.658 Statistics for Psycho-social Research: Structural Models (4) (2nd) 140.662 Spatial Analysis and GIS I (3) (3rd) 140.663 Spatial Analysis and GIS II (4) (4th) INFECTIOUS DISEASE EPIDEMIOLOGY ACADEMIC GUIDE 2013-2014 TRACKS _____________________________________________________________________ General Electives in Infectious Disease Epidemiology All students are required to take one of the courses listed below: Course 340.646 340.651 340.612 340.641 340.744 340.769 340.770 182.640 223.662 223.663 223.665 223.682 223.687 223.689 260.652 260.656 380.761 380.762 Title (credits)(term) Epidemiology and Public Health Impact of HIV and AIDS (4) (1st, in class; 2nd online) Emerging Infections (2) (4th) Epidemiologic Basis for Tuberculosis Control (2) (3rd) Healthcare Epidemiology (4) (2nd) Advanced Topics on Control and Prevention of HIV/AIDS (4) (2nd) Professional Epidemiology Methods (4) (3rd) Public Health Surveillance (3) (4th) Food and Water-Borne Diseases (4) (3rd) Vaccine Development and Application (4) (2nd) Infectious Diseases and Child Survival (3) (3rd) Infection, Immunity and Undernutrition: Interactions and Effects (4) (3rd) Clinical and Epidemiological Aspects of Tropical Diseases (3) (4th) Vaccine Policy Issues (3) (3rd) Biologic Basis of Vaccine Development (3) (4th) Principles of Public Health Ecology (4) (2nd) Malariology (4) (4th) Sexually Transmitted Infections in Public Health Practice (4) (4th) HIV Infection in Women, Children, and Adolescents (4) (4th) ACADEMIC GUIDE 2013-2014 TRACKS _____________________________________________________________________ INFECTIOUS DISEASE EPIDEMIOLOGY Required Courses by Term First Term: Course 340.751 Title (credits) Epidemiologic Methods 1 (5) 140.621 140.651 Statistical Methods in Public Health I (4)* OR Methods in Biostatistics 1 (4) 340.863 340.728 Doctoral Seminars Epidemiology (3) (2nd yr doctoral students only) Advanced Methods for Design and Analysis of Cohort Studies (4) 340.717 340.660 Health Survey Research Methods (4) (2nd yr doctoral students) (offered 2nd term) OR Practical Skills in Conducting Research in Clinical Epidemiology & Investigation (3) 260.611 260.623 260.636 340.728 330.657 140.641 340.646 340.845 Principles of Immunology I (4) Fundamental Virology (4) Evolution of Infectious Disease (3) Advanced Methods for Design and Analysis of Cohort Studies (4) Statistics for Psycho-social Research: Measurement (4) Survival Analysis (3) Epidemiology and Public Health Impact of HIV and AIDS (4) (also offered online in 2nd term) Applied Aspects of Cohort Studies (4) Second Term: Course 340.752 Title (credits) Epidemiologic Methods 2 (5) 140.622 140.652 Statistical Methods in Public Health II (4) OR Methods in Biostatistics II (4) 140.658 340.863 550.865 340.627 Statistics for Psycho-social Research: Structural Models (4) Doctoral Seminars in Epidemiology (3) (2nd year doctoral students only) Public Health Perspectives on Research (2) Epidemiology of Infectious Diseases (4) 260.631 Immunology, Infection and Disease (3) OR Principles of Immunology II (4) 260.612 ACADEMIC GUIDE 2013-2014 TRACKS _____________________________________________________________________ INFECTIOUS DISEASE EPIDEMIOLOGY Course 183.631 260.627 340.744 223.662 Title (credits) Fundamentals of Human Physiology (4) (non-MD, 2nd year doctoral students) Pathogenesis of Bacterial Infections (4) Advanced Topics on Control and Prevention of HIV/AIDS (4) Vaccine Development and Application (4) Third Term: Course 340.753 Title (credits) Epidemiologic Methods 3 (5) 140.623 Statistical Methods in Public Health III (4) OR Methods in Biostatistics III (4) 140.653 340.863 340.609 340.654 260.650 140.662 140.655 340.612 340.769 182.640 223.663 223.665 223.687 260.650 Doctoral Seminars (3) (2nd yr doctoral students only) Concepts and Methods in Infectious Disease Epidemiology (3) Epidemiology and Natural History of Human Viral Infections (6) (also offered online 1st term) Vector Biology and Vector-Borne Diseases (3) Spatial Analysis and GIS I (3) Analysis of Longitudinal Data (4) Epidemiology Basis of Tuberculosis Control (2) Professional Epidemiology Methods (4) Food and Water-Borne Diseases (3) Infectious Diseases and Child Survival (3) Infection, Immunity and Undernutrition (4) Vaccine Policy Issues (3) Vector Biology and Vector-Borne Diseases (3) ACADEMIC GUIDE 2013-2014 TRACKS _____________________________________________________________________ INFECTIOUS DISEASE EPIDEMIOLOGY Fourth Term: Course 340.754** Title (credits) Methodologic Challenges in Epidemiologic Research (5) 140.624 140.654 Statistical Methods in Public Health IV (4) OR Methods in Biostatistics IV* (4) 340.715 340.653 340.677 140.663 140.656 260.622 340.651 340.764 223.682 223.689 260.656 380.761 380.762 Problems in the Design of Epidemiologic Studies (4) (2nd year doctoral students) Epidemiologic Inference in Outbreak Investigations (3) Infectious Disease Dynamics (3) Spatial Analysis and GIS II (4) Multilevel Models in Public Health (4) Principles of Bacterial Infection (3) Emerging Infections (2) Public Health Surveillance (3) Clinical and Epidemiological Aspects of Tropical Diseases (3) Biologic Basis of Vaccine Development (3) Malariology (4) Sexually Transmitted Infections in Public Health Practice (4) HIV in Women, Children, and Adolescents (4) 550.860 Research Ethics (1 )++ course is offered each term. This course meets the School requirements. Students may also take 306.665 or 360.670 to satisfy the ethics requirement. ** Required for doctoral students only Black=department/school wide requirements Red=ID EPI required courses Blue=ID EPI requirement – one biology and one advanced analytical course Purple=ID EPI electives ACADEMIC GUIDE 2013-2014