INTRODUCTION Vitamins and minerals are essential nutrients required in very small amounts and serve as facilitators for normal metabolism, growth and physical health. Most vitamins and minerals are not manufactured in the body so they must be obtained from the diet. Each have different functions in the body and are essential for the biochemical processes within the cells and tissues. Vitamins are either fat soluble (Vitamins A, D, E & K) or water soluble (Vitamins B & C). Fat soluble vitamins can be stored in the body, whereas water soluble vitamins dissolve in water and cannot be stored in the body—thus regular supplementation is required. Minerals are inorganic compounds that originate from the earth and cannot be synthesized by living systems. They are divided into macro minerals (bulk elements) and micro minerals (trace elements). Vitaminico Mineral supplies the essential vitamins and trace minerals that could be lacking in the diet, thus enhancing optimal condition of livestock and companion animals. Properties Vitaminico Mineral contains the following: Vitamin A (150000 I.U) Vitamin D3 Vitamin E (45mg) Vitamin A (retinol) is a fat soluble vitamin and is important for healthy vision, bone growth, reproduction, cell division and cell differentiation. Vitamin A helps regulate the immune system and enhances the function of white blood cells that destroy harmful pathogens. Vitamin A promotes healthy linings of the eyes, respiratory, urinary and intestinal tracts. When those linings breakdown, it becomes easier for infectious agents to enter the body and cause disease. Vitamin A also promotes a healthy skin, mucous membranes and helps prevent growth disorders in young animals and has a protective function against the body’s epithelial cells in older animals. Vitamin D3 is essential for promoting calcium absorption from the gut and maintaining adequate serum calcium and phosphate concentrations to enable normal mineralization of bone and prevent hypoglycemia. It is also needed for bone growth and bone remodeling and therefore called the antirachitic vitamin (prevents rickets). It is important for neuromuscular and immune function and the reduction of inflammation. From a nutritional point of view Vitamin D3 becomes critical if the absolute supply of Ca and P or the ratio of Ca:P is not optimum Vitamin E is the most important lipid-soluble antioxidant, and it protects cell membranes from oxidation by reacting with the lipid radicals. It is important for keeping cell membranes in good condition and maintaining healthy nerves, skin, muscles, red blood cells, heart and circulation. It also enhances the utilization of Vitamin A and is involved in carbohydrate metabolism. It is very important in the regulation and protection of pregnancy. Deficiency Symptoms Deficiency Symptoms Deficiency Symptoms Growth and skin disorders Night blindness Pathological changes in skin and mucosa Reproductive Disorders can also occur Rickets Osteodystrophy Disorders related to Ca and P metabolism Bone, joint and teeth disorders In calves, lambs and pigs muscular dystrophy with lightening of the skeletal musculature (myoglobin loss) and denerative changes in the heart musculature (mulberry heart disease) which can lead to sudden heart failure. Vitamin B1 (140mg) Vitamin B2 (160mg) Vitamin B6 (20mg) 1 Vitamin B is needed to metabolize carbohydrates, fats and protein. Every cell of the body requires vitamin B1 , to form the fuel the body runs on— ATP. Nerve cells and heart muscle require vitamin B1 , in order to function normally, so vitamin B1 is important for normal brain function. Vitamin B1 assists in blood formation and enhances blood circulation. 2 Vitamin B is essential for metabolizing amino acids, carbohydrates and fats to provide energy. Riboflavin is further needed to activate vitamin B6 , helps to create niacin and assists the adrenal gland. Vitamin B2 is required for healthy mucous membranes and in the digestive tract it helps with the absorption of iron and Vitamin B6. It is essential for healthy skin, hair/wool and hooves/claws. Vitamin B6 is needed for the many enzymes involved in protein metabolism. Vitamin B6 through its involvement in protein metabolism and cellular growth, is important to the immune system. It also helps maintain the health of the lymphoid organs. It is essential for red blood cell metabolism and Vitamin B6 is vital in the manufacture of hemoglobin. Vitamin B6 also helps the amount of oxygen carried by hemoglobin. The nervous system requires Vitamin B6 to function efficiently. Vitamin B6 also helps maintain blood glucose within a normal range. Deficiency Symptoms Deficiency Symptoms Deficiency Symptoms Growth depression Disorders of the nervous system Cerebrocortical necrosis (CCN) in calves and cattle Also anorexia and inadequate energy metabolism Growth retardation Poor food utilization Diarrhoea Growth retardation Skin inflammation Nervous disorders Liver and heart damage Nicotinamide (350 mg) Vitamin B12 (25mcg) Calcium Pantothenate (90mg) 5 Nicotinamide via its major metabolite NAD (nicotinamide adenine dinucleotide), is involved in a wide range of biological processes, including the production of energy, the synthesis of fatty acids, cholesterol and steroids. Due to its role as a precursor of NAD, it is an important molecule involved in energy metabolism. This is important in promoting a healthy nervous sytem, skin and healthy gastrointestinal functioning. It also has antioxidant and anti-inflammatory effects Calcium pantothenate (calpan), also know as B , is an antioxidant water soluble vitamin which is needed to break down carbohydrates, proteins and fats. Pantothenic acid is metabolized to coenzyme A via a sequence of steps. Coenzyme A (CoA) is involved in the metabolic release of energy from macronutrients—especially lipids. Vitamin B5 helps metabolize nutrients. Manufacture antibodies and produce vitamin D. It also stimulates the healing of wounds. Vitamin B5 is critical to the manufacture of the red blood cells as well as sex and stressrelated hormones produced in the adrenal glands. Vitamin B12 plays a vital role in the formation and maintenance of the myelin sheath, a protective layer around each nerve, which allows for the quick transmission of nerve impulses. It assists in the production of red blood cells. Vitamin B12 also plays a role in the manufacture if DNS & is involved in fatty acid synthesis and energy production. With an adequate supply of Cobalt, the ruminant can supply its requirements of B12 through microbial synthesis in the rumen. Deficiency Symptoms Deficiency Symptoms Deficiency Symptoms Skin changes Gastrointestinal disorders In dogs: “black Tongue Disease” is typical The deficiency symptoms are not the same in all species. In pigs: “Goose stepping”, higher stress sensitivity, fertility disorders, incomplete genital formation, absence of lactation, decreased suckling reflex in piglets, brown exudates around the eyes. Hair loss, rough hair, hair pigment loss, fatty liver syndrome in all mammals. Rough coat Skin inflammations Growth disorders Anaemia Trace Mineral Mix (10mg) Trace minerals include: Glucose (c.s) Trace minerals are necessary for oxygen transport, energy metabolism, growth, cell and nerve protection. They are essential in the assimilation and utilization of vitamins and other nutrients. They aid in the digestion process and provide the catalyst for many hormones, enzymes and essential body functions and reactions. They aid in replacing electrolytes lost through heavy perspiration or diarrhea. Sodium Iodide Cobalt Cholride Iron Chloride Copper sulphate Magnesium Cholride Sodium selenite Zinc Sulphate Tricalcium Phosphate Sodium Cholride Glucose is an easily available form of energy and the first required sugar in the energy generating process of Glycolysis. Treatment: Recommended daily dosage : assume 1 measure = 12 grams May be administrated in feed or drinking water. In dry mixes the product is very stable but it is preferable that mixes are consumed by animals within 7 days. Preparations in water must be replaced on a daily basis. Horses Cattle Sheep: Pregnant mares in second or third trimester & during Calves: 1/2 measure daily (6gp/dy) Lambs: 1/4 measure p/day (3g p/day) Lactation: 2-4 measures daily (24-48 g p/day) Heifers, cows & bulls: 1/2 to 1 measure Ewes & rams: 1/2 measure daily (6g p/day) Foals recently weaned: 1 measure daily (12g p/day) daily (6-12g p/day) Breeding ewes: during pregnancy and lactation: 1/2 Young horses, stallions & horses in training : 1—2 Pregnant & lactating cattle: 2-4 measures -1 measure daily (6-12 gr) Measures daily (12-24g p/day) daily (24-48g p/day) Ponies: 1/2—1 measure daily (6-12g p/day) Swine Dogs & Cats Breeding sows: during pregnancy & lactation: 1/2-1 1/4-1/2 measure daily (3-6gr p/day) measure daily 96-12g p/day) Boars & younger growers: 1/2 measure daily (6g p/day) Vitaminico™ is a complete vitamin and mineral supplement that can be administered in feed or drinking water . Bedson Africa (Pty) Ltd “Always by your side” Cnr Axle and Battery Str Willows Business Park Silverton Ext 53 Office: 012 803 4376 E-mail: pharma@bedson.co.za Website: www.bedson.co.za